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Cited by 561

The DOI matches its Crossref record; 223 of the 223 references it cites were found in a registry or an index.

Role of adaptive plasticity in recovery of function after damage to motor cortex

Nudo, Randolph J., Plautz, Erik J., Frost, Shawn B.·2001·Muscle & Nerve
DOI 10.1002/mus.1104
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Abstract

Based upon neurophysiologic, neuroanatomic, and neuroimaging studies conducted over the past two decades, the cerebral cortex can now be viewed as functionally and structurally dynamic. More specifically, the functional topography of the motor cortex (commonly called the motor homunculus or motor map), can be modified by a variety of experimental manipulations, including peripheral or central injury, electrical stimulation, pharmacologic treatment, and behavioral experience. The specific types of behavioral experiences that induce long‐term plasticity in motor maps appear to be limited to those that entail the development of new motor skills. Moreover, recent evidence demonstrates that functional alterations in motor cortex organization are accompanied by changes in dendritic and synaptic structure, as well as alterations in the regulation of cortical neurotransmitter systems. These findings have strong clinical relevance as it has recently been shown that after injury to the motor cortex, as might occur in stroke, post‐injury behavioral experience may play an adaptive role in modifying the functional organization of the remaining, intact cortical tissue. © 2001 John Wiley & Sons, Inc. Muscle Nerve 24: 1000–1019, 2001

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Metadata

Authors
Nudo, R. J., Plautz, E. J., & Frost, S. B.
Venue
Muscle & Nerve
Publisher
Wiley
Published
2001-06-29
Volume
24
Issue
8
Pages
1000-1019
ISSN
  • 0148-639X (ISSN-L)
  • 1097-4598
DOI
10.1002/mus.1104
OpenAlex
W2023760861
Cited by
561
References
223
FWCI
28.20
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Role of adaptive plasticity in recovery of function after damage to motor cortex. https://app.cochat.ai/papers/10.1002/mus.1104
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Nudo, R. J., Plautz, E. J., & Frost, S. B. (2001). Role of adaptive plasticity in recovery of function after damage to motor cortex. Muscle & Nerve. https://doi.org/10.1002/mus.1104

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