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Cited by 411

The DOI matches its Crossref record; 110 of the 110 references it cites were found in a registry or an index.

Neuromuscular manifestations of critical illness

Bolton, Charles F.·2005·Muscle & Nerve

Abstract

Critical illness, more precisely defined as the systemic inflammatory response syndrome (SIRS), occurs in 20%–50% of patients who have been on mechanical ventilation for more than 1 week in an intensive care unit. Critical illness polyneuropathy (CIP) and myopathy (CIM), singly or in combination, occur commonly in these patients and present as limb weakness and difficulty in weaning from the ventilator. Critical illness myopathy can be subdivided into thick‐filament (myosin) loss, cachectic myopathy, acute rhabdomyolysis, and acute necrotizing myopathy of intensive care. SIRS is the predominant underlying factor in CIP and is likely a factor in CIM even though the effects of neuromuscular blocking agents and steroids predominate in CIM. Identification and characterization of the polyneuropathy and myopathy depend upon neurological examination, electrophysiological studies, measurement of serum creatine kinase, and, if features suggest a myopathy, muscle biopsy. The information is valuable in deciding treatment and prognosis. Muscle Nerve, 2005

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Metadata

Authors
Bolton, C. F.
Venue
Muscle & Nerve
Publisher
Wiley
Published
2005-04-11
Volume
32
Issue
2
Pages
140-163
ISSN
  • 0148-639X (ISSN-L)
  • 1097-4598
OpenAlex
W1977493330
Cited by
411
References
110
FWCI
18.21
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Neuromuscular manifestations of critical illness. https://app.cochat.ai/papers/10.1002/mus.20304
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Bolton, C. F. (2005). Neuromuscular manifestations of critical illness. Muscle & Nerve. https://doi.org/10.1002/mus.20304

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