The DOI matches its Crossref record; 22 of the 22 references it cites were found in a registry or an index.
Body mass index, not dyslipidemia, is an independent predictor of survival in amyotrophic lateral sclerosis
Open accessAbstract
Introduction: Recent studies have provided conflicting data regarding the role of dyslipidemia in amyotrophic lateral sclerosis (ALS). The aim of this study was to determine whether cholesterol level are an independent predictor of survival in ALS. Methods: Cholesterol levels were measured in 427 ALS subjects from three clinical trial databases. Results: The LDL/HDL ratio did not decrease over time, despite significant declines in body mass index (BMI), forced vital capacity (FVC), and ALSFRS‐R. After adjusting for BMI, FVC, and age, the lipid ratio was not associated with survival. There was a “U”‐shaped association between BMI and mortality, with the highest survival at 30–35 kg/m 2. The adjusted hazard ratio for the linear association between BMI and survival was 0.860 (95% CI 0.80–0.93, P = 0.0001). Conclusions: We found that dyslipidemia is not an independent predictor of survival in ALS. BMI is an independent prognostic factor for survival after adjusting for markers of disease severity. Muscle Nerve, 2011
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El Escorial revisited: revised criteria for the diagnosis of amyotrophic lateral sclerosis
Brooks, B. R., Miller, R. G., Swash, M., & Munsat, T. L. (2000) · Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders · doi:10.1080/146608200300079536 · Cited by 5,433
Dyslipidemia is a protective factor in amyotrophic lateral sclerosis
Dupuis, L., Corcia, P., Fergani, A., Gonzalez De Aguilar, J. L., Bonnefont-Rousselot, D., Bittar, R., Seilhean, D., Hauw, J. J., Lacomblez, L., Loeffler, J. P., et al. (2008) · Neurology · doi:10.1212/01.wnl.0000285080.70324.27 · Cited by 552
Energy metabolism in amyotrophic lateral sclerosis
Dupuis, L., Pradat, P.-F., Ludolph, A. C., & Loeffler, J.-P. (2011) · The Lancet Neurology · doi:10.1016/s1474-4422(10)70224-6 · Cited by 537
Nutritional status is a prognostic factor for survival in ALS patients
Desport, J. C., Preux, P. M., Truong, T. C., Vallat, J. M., Sautereau, D., & Couratier, P. (1999) · Neurology · doi:10.1212/wnl.53.5.1059 · Cited by 486
Factors correlated with hypermetabolism in patients with amyotrophic lateral sclerosis
Desport, J. C., Preux, P. M., Magy, L., Boirie, Y., Vallat, J. M., Beaufrère, B., & Couratier, P. (2001) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/74.3.328 · Cited by 351
Hypermetabolism in ALS patients: an early and persistent phenomenon
Bouteloup, C., Desport, J.-C., Clavelou, P., Guy, N., Derumeaux-Burel, H., Ferrier, A., & Couratier, P. (2009) · Journal of Neurology · doi:10.1007/s00415-009-5100-z · Cited by 344
Trial of celecoxib in amyotrophic lateral sclerosis
Cudkowicz, M. E., Shefner, J. M., Schoenfeld, D. A., Zhang, H., Andreasson, K. I., Rothstein, J. D., Drachman, D. B., & Northeast ALS Consortium (2006) · Annals of Neurology · doi:10.1002/ana.20903 · Cited by 301
Self-citationKasarskis, E., Berryman, S., Vanderleest, J., Schneider, A., & McClain, C. (1996) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/63.1.130 · Cited by 293
A ketogenic diet as a potential novel therapeutic intervention in amyotrophic lateral sclerosis
Zhao, Z., Lange, D. J., Voustianiouk, A., MacGrogan, D., Ho, L., Suh, J., Humala, N., Thiyagarajan, M., Wang, J., & Pasinetti, G. M. (2006) · BMC Neuroscience · doi:10.1186/1471-2202-7-29 · Cited by 286
Dorst, J., Kühnlein, P., Hendrich, C., Kassubek, J., Sperfeld, A. D., & Ludolph, A. C. (2011) · Journal of Neurology · doi:10.1007/s00415-010-5805-z · Cited by 263
Cited by
ESPEN guideline clinical nutrition in neurology
Burgos, R., Bretón, I., Cereda, E., Desport, J. C., Dziewas, R., Genton, L., Gomes, F., Jésus, P., Leischker, A., Muscaritoli, M., et al. (2018) · Clinical Nutrition · doi:10.1016/j.clnu.2017.09.003 · Cited by 571
Wang, M.-D., Little, J., Gomes, J., Cashman, N. R., & Krewski, D. (2017) · NeuroToxicology · doi:10.1016/j.neuro.2016.06.015 · Cited by 233
Vercruysse, P., Vieau, D., Blum, D., Petersén, Å., & Dupuis, L. (2018) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2018.00002 · Cited by 172
Diabetes Mellitus, Obesity, and Diagnosis of Amyotrophic Lateral Sclerosis: A Population-Based Study
Kioumourtzoglou, M.-A., Rotem, R. S., Seals, R. M., Gredal, O., Hansen, J., & Weisskopf, M. G. (2015) · JAMA Neurology · doi:10.1001/jamaneurol.2015.0910 · Cited by 145
Causal effects of blood lipids on amyotrophic lateral sclerosis: a Mendelian randomization study
Zeng, P., & Zhou, X. (2019) · Human Molecular Genetics · doi:10.1093/hmg/ddy384 · Cited by 130
Metadata
- Authors
- Paganoni, S., Deng, J., Jaffa, M., Cudkowicz, M. E., & Wills, A.
- Venue
- Muscle & Nerve
- Publisher
- Wiley
- Published
- 2011-05-23
- Volume
- 44
- Issue
- 1
- Pages
- 20-24
- ISSN
- 0148-639X (ISSN-L)
- 1097-4598
- OpenAlex
- W2131177410
- Cited by
- 293
- References
- 22
- FWCI
- 8.96
- Type
- journal article
- Language
- en
- Open access
- green
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