The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Gestational weight loss and perinatal outcomes in overweight and obese women subsequent to diagnosis of gestational diabetes mellitus
Open accessAbstract
Objective: To investigate whether gestational weight loss (GWL) after the diagnosis of gestational diabetes mellitus (GDM) in overweight and obese women is associated with improved perinatal outcomes. Obesity and GDM are risk factors for adverse perinatal outcomes, but few studies have investigated weight loss during pregnancy in women with these comorbidities. Design and Methods: Retrospective cohort study of 26,205 overweight and obese gestational diabetic women enrolled in the California Diabetes and Pregnancy Program. Women with GWL during program enrollment were compared to those with weight gain. Perinatal outcomes were assessed using chi‐square test and multivariable logistic regression analysis. Results: About 5.2% of women experienced GWL. GWL was associated with decreased odds of macrosomia (aOR 0.63, 95% CI 0.52‐0.77), NICU admission (aOR 0.51, 95% CI 0.27‐0.95), and cesarean delivery (aOR 0.81, 95% CI 0.68‐0.97). Odds of SGA status (aOR 1.69, 95% CI 1.32‐2.17) and preterm delivery <34 weeks (aOR 1.71, 95% CI 1.23‐2.37) were increased. Conclusions: In overweight and obese women with GDM, third trimester weight loss is associated with some improved maternal and neonatal outcomes, although this effect is lessened by increased odds of SGA status and preterm delivery. Further research on weight loss and interventions to improve adherence to weight guidelines in this population is recommended.
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Modest energy restriction in women with GDM does not increase adverse outcomes or SGA rates compared to the baseline population.
“Emerging evidence suggests that modest energy restriction in women with GDM does not increase adverse outcomes or SGA rates compared to the baseline population [60,61,62].”
From Medical Nutrition Therapy for Women with Gestational Diabetes: Current Practice and Future Perspectives (2025) · cites this paper as [62]
The Results report increased SGA status and preterm delivery before 34 weeks among women who lost weight after a GDM diagnosis, compared with women who did not lose weight. This contradicts the claim that SGA rates and adverse outcomes did not increase. The study examined observed weight loss in overweight and obese women with GDM, not an intervention imposing modest energy restriction. (LLM, conf=0.91)
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Cites
Weight gain as a risk factor for clinical diabetes mellitus in women
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Effect of BMI on Lifetime Risk for Diabetes in the U.S.
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Gestational Weight Gain and Pregnancy Outcomes in Obese Women: How Much Is Enough?
Kiel, D. W., Dodson, E. A., Artal, R., Boehmer, T. K., & Leet, T. L. (2007) · Obstetrics & Gynecology · doi:10.1097/01.aog.0000278819.17190.87 · Cited by 498 · cited 11×
“While we observed that the frequency of preterm delivery and SGA status were increased in the weight loss group, the overall incidences of these adverse outcomes were low.”
BackgroundInfluentialThe effect of gestational weight gain by body mass index on maternal and neonatal outcomes
Crane, J. M. G., White, J., Murphy, P., Burrage, L., & Hutchens, D. (2009) · Journal of Obstetrics and Gynaecology Canada · doi:10.1016/s1701-2163(16)34050-6 · Cited by 363 · cited 1×
“These guidelines include more specific, narrower ranges of recommended weight gain for obese women, as excessive gestational weight gain has been clearly associated with multiple types of neonatal and maternal morbidity and mortality (7,8,10-13).”
BackgroundBlomberg, M. (2011) · Obstetrics & Gynecology · doi:10.1097/aog.0b013e318214f1d1 · Cited by 174
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Cheong, L., Law, L. S.-C., Tan, L. Y. L., Amal, A. A.-A., Khoo, C. M., & Eng, P. C. (2025) · Nutrients · doi:10.3390/nu17071210 · Cited by 14
Metadata
- Authors
- Yee, L. M., Cheng, Y. W., Inturrisi, M., & Caughey, A. B.
- Affiliations
- Northwestern University (US)
- University of California, San Francisco (US)
- Oregon Health & Science University (US)
- Venue
- Obesity
- Publisher
- Wiley
- Published
- 2013-07-05
- Volume
- 21
- Issue
- 12
- Pages
- E770-4
- ISSN
- 1930-7381 (ISSN-L)
- 1930-739X
- PMC
- PMC3758809
- OpenAlex
- W2148928677
- Cited by
- 27
- References
- 6
- Citations by year
- 2026: 2 · 2025: 2 · 2022: 3 · 2021: 3 · 2020: 2 · 2019: 2 · 2018: 3 · 2017: 1 · 2016: 2 · 2015: 2 · 2014: 3 · 2013: 2
- FWCI
- 3.36
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Obesity (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- World Health Organization
- University of California, San Francisco
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (K12HD001262)
- Topics
- Health Sciences › Medicine › Obstetrics and Gynecology › Gestational Diabetes Research and Management
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Maternal and Neonatal Healthcare
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Keywords
- gestational diabetes mellitus, maternal obesity, overweight women, perinatal outcomes, macrosomia, small for gestational age, preterm birth, cesarean section, neonatal intensive care admission
- MeSH terms
- Adult, California, Cesarean Section, Female, Fetal Macrosomia, Humans, Obesity, Pregnancy, Pregnancy Complications, Pregnancy Outcome, Pregnancy Trimester, Third, Retrospective Studies, Weight Loss, Body Mass Index, Multivariate Analysis, Logistic Models, Diabetes, Gestational, Overweight
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