The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Energetic adaptations persist after bariatric surgery in severely obese adolescents
Abstract
Objective: Energetic adaptations induced by bariatric surgery have not been studied in adolescents or for extended periods postsurgery. Energetic, metabolic, and neuroendocrine responses to Roux‐en‐Y gastric bypass (RYGB) surgery were investigated in extremely obese adolescents. Methods: At baseline and at 1.5, 6, and 12 months post‐baseline, 24‐h room calorimetry, body composition, and fasting blood biochemistries were measured in 11 obese adolescents relative to five matched controls. Results: In the RYGB group, mean weight loss was 44 ± 19 kg at 12 months. Total energy expenditure (TEE), activity EE, basal metabolic rate (BMR), sleep EE, and walking EE significantly declined by 1.5 months (P= 0.001) and remained suppressed at 6 and 12 months. Adjusted for age, sex, fat‐free mass, and fat mass, EE was still lower than baseline (P= 0.001). Decreases in serum insulin, leptin, and triiodothyronine (T3), gut hormones, and urinary norepinephrine (NE) paralleled the decline in EE. Adjusted changes in TEE, BMR, and/or sleep EE were associated with decreases in insulin, homeostatic model assessment, leptin, thyroid stimulating hormone, total T3, peptide YY3‐36, glucagon‐like peptide‐2, and urinary NE and epinephrine (P= 0.001‐0.05). Conclusions: Energetic adaptations in response to RYGB‐induced weight loss are associated with changes in insulin, adipokines, thyroid hormones, gut hormones, and sympathetic nervous system activity and persists 12 months postsurgery.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The check wasn’t confident either way, so it gives no verdict — never disputed.
In the citing paper
“AT was independent of macronutrient composition of the diet [44–47].”
From Changes in energy expenditure with weight gain and weight loss in humans (2016) · cites this paper as [47]
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Matthews, D. R., Hosker, J. P., Rudenski, A. S., Naylor, B. A., Treacher, D. F., & Turner, R. C. (1985) · Diabetologia · doi:10.1007/bf00280883 · Cited by 31,502
The Biology of Human Starvation: Volume I
KEYS, A., BROŽEK, J., HENSCHEL, A., MICKELSEN, O., & TAYLOR, H. L. (1950) · doi:10.5749/j.ctv9b2tqv · Cited by 2,039
Changes in Energy Expenditure Resulting from Altered Body Weight
Leibel, R. L., Rosenbaum, M., & Hirsch, J. (1995) · New England Journal of Medicine · doi:10.1056/nejm199503093321001 · Cited by 2,012
Rosenbaum, M. (2005) · Journal of Clinical Investigation · doi:10.1172/jci25977 · Cited by 575
Changes in fat-free mass during significant weight loss: a systematic review
Chaston, T. B., Dixon, J. B., & O'Brien, P. E. (2007) · International Journal of Obesity · doi:10.1038/sj.ijo.0803483 · Cited by 493
Adaptive thermogenesis in humans
Rosenbaum, M., & Leibel, R. L. (2010) · International Journal of Obesity · doi:10.1038/ijo.2010.184 · Cited by 349
Effects of experimental weight perturbation on skeletal muscle work efficiency in human subjects
Rosenbaum, M., Vandenborne, K., Goldsmith, R., Simoneau, J.-A., Heymsfield, S., Joanisse, D. R., Hirsch, J., Murphy, E., Matthews, D., Segal, K. R., et al. (2003) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00474.2002 · Cited by 255 · cited 1×
“A series of studies explored whether energetic adaptations were a result of caloric restriction during active weight loss or maintenance of a reduced weight after conventional weight loss (6,23,30,36,37).”
Background
Research works printed but not linked: 32
- 10.1016/j.tem.2010.01.006 · DOI
- 10.1016/j.jada.2009.12.023 · DOI
- 10.1542/peds.2008-0522 · DOI
- 10.1016/j.ghir.2006.03.013 · DOI
- 10.1016/j.mcna.2007.02.004 · DOI
- 10.1093/ajcn/88.4.906 · DOI · Paper page
- 10.1007/s11695-012-0839-1 · DOI
- 10.1038/oby.2010.89 · DOI
- 10.1038/sj.ijo.0801230 · DOI
- 10.1038/oby.2012.34 · DOI
- 10.1093/ajcn/72.4.946 · DOI
- 10.1210/jcem.85.3.6447 · DOI · Paper page
- Astrup A, 1992, 24‐Hour energy expenditure and sympathetic activity in postobese women consuming a high‐carbohydrate diet, Am J Physiol, 262, E282
- 10.1093/ajcn/71.5.1138 · DOI
- 10.1042/cs0820687 · DOI
- 10.1093/ajcn/45.5.905 · DOI
- Wong WW, 1992, A new zinc product for the reduction of water in physiological fluids to hydrogen gas for 2H/1H isotope ratio measurements, Eur J Clin Nutr, 46, 69
- 10.1021/ac60252a045 · DOI · Paper page
- Moon JK, 1995, Closed‐loop control of carbon dioxide concentration and pressure improves response of room respiration calorimeters, J Nutr, 125, 220, 10.1093/jn/125.2.220 · DOI
- 10.1093/ajcn/47.4.608 · DOI
- 10.1126/science.177.4045.222 · DOI
- 10.1016/j.jpeds.2005.03.021 · DOI
- 10.1161/01.CIR.103.4.513 · DOI
- 10.1016/j.neuropharm.2011.12.010 · DOI
- 10.1016/j.mce.2009.06.005 · DOI
- 10.1093/ajcn/71.6.1421 · DOI · Paper page
- 10.1111/nyas.12374 · DOI
- 10.1001/jama.295.13.1539 · DOI · Paper page
- 10.1152/ajpendo.00171.2011 · DOI
- 10.1038/oby.2006.180 · DOI
- 10.1152/ajpendo.00450.2006 · DOI
- 10.1007/s11695-009-9842-6 · DOI
Cited by
Sorted by citations
Changes in energy expenditure with weight gain and weight loss in humans
Müller, M. J., Enderle, J., & Bosy-Westphal, A. (2016) · Current Obesity Reports · doi:10.1007/s13679-016-0237-4 · Cited by 267
Busetto, L., Bettini, S., Makaronidis, J., Roberts, C. A., Halford, J. C. G., & Batterham, R. L. (2021) · European Journal of Internal Medicine · doi:10.1016/j.ejim.2021.01.002 · Cited by 159
Guan, B., Chen, Y., Yang, J., Yang, W., & Wang, C. (2017) · Obesity Surgery · doi:10.1007/s11695-017-2965-2 · Cited by 79
Exercise and bariatric surgery: an effective therapeutic strategy
Coen, P. M., Carnero, E. A., & Goodpaster, B. H. (2018) · Exercise and Sport Sciences Reviews · doi:10.1249/jes.0000000000000168 · Cited by 71
Bariatric Surgery in Adults with Obesity: the Impact on Performance, Metabolism, and Health Indices
Jabbour, G., & Salman, A. (2021) · Obesity Surgery · doi:10.1007/s11695-020-05182-z · Cited by 60
Metadata
- Authors
- Butte, N. F., Brandt, M. L., Wong, W. W., Liu, Y., Mehta, N. R., Wilson, T. A., Adolph, A. L., Puyau, M. R., Vohra, F. A., Shypailo, R. J., & Zakeri, I. F.
- Affiliations
- USDA/ARS Children's Nutrition Research Center, Department of Pediatrics Baylor College of Medicine Houston Texas USA
- Department of Surgery Baylor College of Medicine Houston Texas USA
- Department of Epidemiology and Biostatistics Drexel University Philadelphia Pennsylvania USA.
- Venue
- Obesity
- Publisher
- Wiley
- Published
- 2015-02-24
- Volume
- 23
- Issue
- 3
- Pages
- 591-601
- ISSN
- 1930-7381
- 1930-739X
- PMC
- PMC4340087
- Cited by
- 55
- References
- 7
- Language
- en
- Funders
- Office of Extramural Research, National Institutes of Health (U01DK072493/ UM1 DK072493/UM1DK095710)
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Energetic adaptations persist after bariatric surgery in severely obese adolescents. https://app.cochat.ai/papers/10.1002/oby.20994
- The paper
- Butte, N. F., Brandt, M. L., Wong, W. W., Liu, Y., Mehta, N. R., Wilson, T. A., Adolph, A. L., Puyau, M. R., Vohra, F. A., Shypailo, R. J., & Zakeri, I. F. (2015). Energetic adaptations persist after bariatric surgery in severely obese adolescents. Obesity. https://doi.org/10.1002/oby.20994
