HER2 overexpression and amplification as a potential therapeutic target in colorectal cancer: analysis of 3256 patients enrolled in the QUASAR , FOCUS and PICCOLO colorectal cancer trials

Richman, Susan D, Southward, Katie, Chambers, Philip, Cross, Debra, Barrett, Jennifer, Hemmings, Gemma, Taylor, Morag, Wood, Henry +11 more·2016·The Journal of Pathology

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  5. The diagnostic molecular pathology of colorectal carcinoma using automated PCR
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  8. Study on Prognostic Implications of HER2/Neu Expression in Colorectal Cancer in Eastern India
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  9. Development of HER2 -targeted Therapies for Gastrointestinal Cancer
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  10. ISH-basierte HER2-Diagnostik
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  11. An Introduction to the Current Management of Colorectal Cancer in the Era of Personalized Oncology
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  12. Actualización de la recomendación para la determinación de biomarcadores en el carcinoma colorrectal. Consenso Nacional de la Sociedad Española de Oncología Médica y de la Sociedad Española de Anatomía Patológica
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  14. Evolving Role of Circulating Tumor DNA and Emerging Targeted Therapy in Colorectal Cancer
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  15. Role of dual anti-HER2 therapy before liver resection for rectal metastases
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  16. Indications of Genomic Abnormalities for Molecular Targeted Therapy in Colorectal Cancer
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  17. Treatment Refractory Metastatic Colorectal Cancer
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  18. HER2 ‘neu’ promise for mCRC
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  19. Molecular Testing of Gastrointestinal Neoplasms
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  21. Additional file 1 of Development and clinical validation of a novel six-gene signature for accurately predicting the recurrence risk of patients with stage II/III colorectal cancer
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  22. Current treatment options of HER2+ metastatic colorectal carcinoma
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  23. Novel Therapies for Colorectal Cancers
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  24. Efficacy of disitamab vedotin-containing therapy in metastatic colorectal cancer: A case report
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  25. A case report of HER2-positive descending colon cancer with peritoneal metastasis and literature review
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  26. Endoscopic features of deficient mismatch repair/microsatellite instability‐high and BRAF‐mutated colorectal cancer
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  27. Radical treatment for metastasis of HER2‑positive rectal adenocarcinoma to the liver: A case report and literature review
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  28. Characterization of the Tumor Immune Microenvironment in HER2-Positive Colorectal Cancer: Association With Prognostic and Therapeutic Implications
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  29. Molecular Targets in Metastatic Colorectal Cancer: A Review
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  30. Survival outcomes of ERBB2-amplified metastatic colorectal cancer treated with first-line chemotherapy
    Yuki Matsubara, Hideaki Bando, Yoshiaki Nakamura, Toshihiro Misumi, Dionne Ng, Eri Tajima, Harlan Pittell, Atsushi Ohtsu, Takayuki Yoshino · 2025 · British Journal of Cancer
  31. Additional file 2 of Development and clinical validation of a novel six-gene signature for accurately predicting the recurrence risk of patients with stage II/III colorectal cancer
    Liu, Zaoqu, Lu, Taoyuan, Li, Jing, Wang, Libo, Kaihao Xu, Dang, Qin, Guo, Chunguang, Liu, Long, 焦德超, Sun, Zhenqiang et al. · 2021 · Figshare
  32. Additional file 1 of Temporal and spatial heterogeneity of HER2 status in metastatic colorectal cancer
    Flavia D’Angelo, Franck Monnien, Alexis Overs, Irvin Pem, Fanny Dor, Marine Abad, Felix, Sophie, Zohair Selmani, Zaher Lakkis, Christophe Borg et al. · 2024 · Figshare
  33. Actionable subgroups (II): HER2+, NTRK/RET/ALK and MSI-H/TMB high
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  34. Prognostic and Treatment-Specific Predictive Implications of HER2 Expression in RAS Wild-Type Metastatic Colorectal Cancer: A Multicenter Retrospective Real-World Study
    Özlem Özdemir, Damla Günenç, Halil Taşkaynatan, Pınar Peker, Emir Gökhan Kahraman, Sedat Biter, Semra Paydaş, Tuğba Önder, Öztürk Ateş, Muhammed Muhiddin Er et al. · 2026 · Journal of Clinical Medicine
  35. HER2 overexpression/amplification in colorectal cancer: spatial intratumoral heterogeneity as a key determinant of detection discordance and therapy response
    Xiaoding Liu, Si Su, Xuqing Shi, Junyi Pang, Xinyi Teng, Longyun Chen, Hangqi Liu, Zijuan Zhang, Yaxuan Miao, Xicheng Wang et al. · 2026 · Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin
  36. Rechallenge With Anti-Human Epidermal Growth Factor Receptor 2 Therapy Guided by Liquid Biopsy in HER2 -Amplified Metastatic Colorectal Cancer
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  37. Integrative Profiling of Tumor and Blood Microenvironments to Uncover Molecular and Immune Determinants of Prognosis and Treatment Efficacy in Metastatic Colorectal Cancer
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  38. Unlocking HER2 as a target in KRAS-mutated rectal cancer: a case of significant response to zanidatamab-based regimen
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  39. Clinical significance of WES-defined ERBB2 amplification in resectable colorectal cancer
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  40. Clinicopathological Characteristics and Prognostic Significance of High, Low, and Absent HER2 Expression Status in Colorectal Cancer
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  41. Translating Biology into Biomarker-Driven Surgical Practice in Localized Colorectal Cancer
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