The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Prenatal screening and diagnosis of neural tube defects
Abstract
This review article discusses prenatal screening and diagnosis of neural tube defects (NTD). High detection rates occur in countries operating ultrasound screening programmes because classical two‐dimensional ultrasound cranial signs (lemon shaped head, banana cerebellum, ventriculomegaly) are important diagnostic clues to the presence of spina bifida. Careful evaluation of both the spine and a search for other abnormalities is warranted. Important prognostic information for spina bifida relates to the lesion level, with a “watershed” between L3 and L4 marking a very high chance of being wheelchair bound with the higher lesions. Three‐dimensional ultrasound using multiplanar views can achieve diagnostic accuracy within one vertebral body in around 80% of patients. There are high rates of pregnancy termination for spina bifida in many European countries, but the use of new imagining techniques allow better prediction of outcome, and consequently a refinement of prenatal counselling. Copyright © 2009 John Wiley & Sons, Ltd.
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Cites
Boyd, P., DeVigan, C., Khoshnood, B., Loane, M., Garne, E., Dolk, H., & EUROCAT working group (2008) · BJOG: An International Journal of Obstetrics & Gynaecology · doi:10.1111/j.1471-0528.2008.01700.x · Cited by 335
Evaluation of the lemon and banana signs in one hundred thirty fetuses with open spina bifida
Van den Hof, M. C., Nicolaides, K. H., Campbell, J., & Campbell, S. (1990) · American Journal of Obstetrics and Gynecology · doi:10.1016/0002-9378(90)90378-k · Cited by 207
Cited by
Greene, N. D. E., & Copp, A. J. (2014) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-062012-170354 · Cited by 629
Neural tube defects—disorders of neurulation and related embryonic processes
Copp, A. J., & Greene, N. D. E. (2013) · WIREs Developmental Biology · doi:10.1002/wdev.71 · Cited by 268
Neural Tube Defects: A Review of Global Prevalence, Causes, and Primary Prevention
Kancherla, V. (2023) · Child's Nervous System · doi:10.1007/s00381-023-05910-7 · Cited by 145
An, D., Wei, X., Li, H., Gu, H., Huang, T., Zhao, G., Liu, B., Wang, W., Chen, L., Ma, W., et al. (2015) · Scientific Reports · doi:10.1038/srep17559 · Cited by 67
Harnessing Artificial Intelligence for Health Message Generation: The Folic Acid Message Engine
Schmälzle, R., & Wilcox, S. (2022) · Journal of Medical Internet Research · doi:10.2196/28858 · Cited by 43
Metadata
- Authors
- Cameron, M., & Moran, P.
- Venue
- Prenatal Diagnosis
- Publisher
- Wiley
- Published
- 2009-03-19
- Volume
- 29
- Issue
- 4
- Pages
- 402-411
- ISSN
- 0197-3851 (ISSN-L)
- 1097-0223
- OpenAlex
- W1971788694
- Cited by
- 196
- References
- 2
- FWCI
- 13.59
- Type
- journal article
- Language
- en
- Open access
- closed
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