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Trends in potentially inappropriate medication prescribing to nursing home patients: comparison of three cross-sectional studies: Inappropriate Medication Prescribing in Norwegian Nursing Homes
Abstract
PURPOSE: The aim of this study was to examine trends in potentially inappropriate medication (PIM) prescribing in Norwegian nursing homes. METHODS: Patients aged ≥70 years were included from three cross-sectional studies conducted in 1997, 2005 and 2011. PIMs were analyzed according to the Norwegian General Practice-Nursing Home criteria (NORGEP-NH), use of single substances to avoid, combinations to avoid, and deprescribing items. Associations between sample and use of PIMs were examined by logistic regression, adjusted for age, gender, and ward. We established Pearsons r for correlations between numbers of drugs and PIMs. RESULTS: Altogether, 4373 patients (mean age 85.7 years, 73.5% women) were included. The mean overall number of drugs per patient increased from 4.7 in 1997 to 6.9 in 2011 (p < 0.001). Use of any single substances to avoid increased from 36.8% in 1997 to 39.5% in 2011 (p = 0.002), use of any combinations to avoid from 16.3% to 27.0% (p < 0.001), and use of any deprescribing items from 46.0% to 55.3% (p < 0.001). Use of codeine-analgesics, nonsteroidal anti-inflammatory drugs, tricyclic antidepressants, long-acting benzodiazepines, and first generation antihistamines decreased significantly, while use of short-acting benzodiazepines, z-hypnotics, statins, and anti-dementia drugs increased significantly. A moderate strong correlation was detected between number of drugs and the three above-mentioned PIM categories, r = 0.34, r = 0.43, r = 0.37, respectively (all p < 0.001). CONCLUSIONS: Although several PIMs were less commonly prescribed in recent years, increased overall use of PIMs may suggests worsening of prescribing quality for nursing home patients in Norway. Copyright © 2016 John Wiley & Sons, Ltd.
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Many of our findings are also consistent with general themes relating to medication use in older people found in previous studies.
“Many of our findings are also consistent with general themes relating to medication use in older people found in previous studies. They include negative self-perceptions of ageing with declining health, more perceived barriers to care [88–90] and high levels of general inappropriate prescribing in residential homes [91].”
From Stakeholders' views on the use of psychotropic medication in older people: a systematic review (2022) · cites this paper as [91]
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Stakeholders' views on the use of psychotropic medication in older people: a systematic review
Bednarczyk, E., Cook, S., Brauer, R., & Garfield, S. (2022) · Age and Ageing · doi:10.1093/ageing/afac060 · Cited by 22
Metadata
- Authors
- Halvorsen, K. H., Selbaek, G., & Ruths, S.
- Affiliations
- UiT The Arctic University of Norway (NO)
- Norwegian National Advisory Unit on Ageing and Health, Vestfold Hospital Trust; Tønsberg Norway
- Uni Research (Norway) (NO)
- Corresponding author
- Halvorsen, Kjell H.
- Venue
- Pharmacoepidemiology and Drug Safety
- Publisher
- Wiley
- Published
- 2016-12-09
- Volume
- 26
- Issue
- 2
- Pages
- 192-200
- ISSN
- 1053-8569 (ISSN-L)
- OpenAlex
- W2560012329
- Cited by
- 41
- References
- 37
- Citations by year
- 2025: 2 · 2024: 2 · 2023: 4 · 2022: 7 · 2021: 10 · 2020: 5 · 2019: 6 · 2018: 3 · 2017: 2
- FWCI
- 2.11
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Pharmacoepidemiology and Drug Safety (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Geriatrics and Gerontology › Pharmaceutical Practices and Patient Outcomes
- Health Sciences › Medicine › Geriatrics and Gerontology › Geriatric Care and Nursing Homes
- Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Opioid Use
- Keywords
- potentially inappropriate medications, nursing home residents, older adults, prescribing trends, polypharmacy, deprescribing, benzodiazepines, antihistamines, analgesics, antidepressants, anti-dementia drugs, prescribing quality, Norwegian nursing homes
- MeSH terms
- Potentially Inappropriate Medication List, Aged, Aged, 80 and over, Cross-Sectional Studies, Female, Homes for the Aged, Humans, Male, Norway, Nursing Homes, Practice Patterns, Physicians', Quality of Health Care, Prescription Drugs, Inappropriate Prescribing
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