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Synthesis and characterization of poly(ethylene glycol) derivatives
Open accessAbstract
Five general routes for the preparation of polyoxyethylene [generally referred to as poly(ethylene glycol) or PEG] derivatives are described. These routes are (1) nucleophilic displacements with the alkoxide of PEG, (2) nucleophilic displacement on PEG–tosylate, –mesylate, or –bromide, (3) reductive amination of PEG–aldehyde, (4) reductive amination of PEG–amine, and (5) nucleophilic displacements on the s‐triazine derivatives prepared from s‐triazine trichloride (cyanuric chloride) and PEG. Eighteen derivatives are prepared and potential applications to catalysis, cell purifications, and other areas are discussed briefly.
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Citations
Cited by
Main properties and current applications of some polysaccharides as biomaterials
Rinaudo, M. (2008) · Polymer International · doi:10.1002/pi.2378 · Cited by 1,028
PEG-grafted chitosan as an injectable thermosensitive hydrogel for sustained protein release
Bhattarai, N., Ramay, H. R., Gunn, J., Matsen, F. A., & Zhang, M. (2005) · Journal of Controlled Release · doi:10.1016/j.jconrel.2004.12.019 · Cited by 656
Water-soluble dendritic unimolecular micelles:
Liu, M., Kono, K., & Fréchet, J. M. J. (2000) · Journal of Controlled Release · doi:10.1016/s0168-3659(99)00245-x · Cited by 477
Effect of Chain Density on Inhibition of Protein Adsorption by Poly(ethylene glycol) Based Coatings
Malmsten, M., Emoto, K., & Van Alstine, J. M. (1998) · Journal of Colloid and Interface Science · doi:10.1006/jcis.1998.5513 · Cited by 342
Self-citationSynthesis of protein–polymer conjugates
Heredia, K. L., & Maynard, H. D. (2007) · Org. Biomol. Chem. · doi:10.1039/b612355d · Cited by 324
Metadata
- Authors
- Harris, J. M., Struck, E. C., Case, M. G., Paley, M. S., Yalpani, M., Van Alstine, J. M., & Brooks, D. E.
- Venue
- Journal of Polymer Science: Polymer Chemistry Edition
- Publisher
- Wiley
- Published
- 1984-02
- Volume
- 22
- Issue
- 2
- Pages
- 341-352
- ISSN
- 0360-6376 (ISSN-L)
- 1542-9369
- OpenAlex
- W2140395383
- Cited by
- 307
- References
- 0
- FWCI
- 10.00
- Type
- journal article
- Language
- en
- Open access
- bronze
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- The paper
- Harris, J. M., Struck, E. C., Case, M. G., Paley, M. S., Yalpani, M., Van Alstine, J. M., & Brooks, D. E. (1984). Synthesis and characterization of poly(ethylene glycol) derivatives. Journal of Polymer Science: Polymer Chemistry Edition. https://doi.org/10.1002/pol.1984.170220207
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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