Cited by 1,028Polysaccharides Composition and ApplicationsHydrogels: synthesis, properties, applicationsAdvanced Drug Delivery Systems

Main properties and current applications of some polysaccharides as biomaterials

Rinaudo, Marguerite·2008·Polymer International

Abstract

This review concerns the applications of some polysaccharides in the domain of biomaterials and bioactive polymers. Natural polysaccharides from different sources have been studied for a long time, and their main properties are summarized in this paper; some of their derivatives obtained by chemical modification are also described. The main polysaccharides currently used in the biomedical and pharmaceutical domains are chitin and its derivative chitosan, hyaluronan and alginates. Alginates are well known for their property of forming a physical gel in the presence of divalent counterions (Ca, Ba, Sr) whereas carrageenans form a thermoreversible gel; these seaweed polysaccharides are mainly used to encapsulate different materials (cells, bacteria, fungi). Other promising systems are the electrostatic complexes formed when an anionic polysaccharide is mixed with a cationic polysaccharide (e.g. alginate/chitosan or hyaluronan/chitosan). An important development of the applications of polysaccharides can be predicted for the next few years in relation to their intrinsic properties such as biocompatibility and biodegradability in the human body for some of them; they are also renewable and have interesting physical properties (film‐forming, gelling and thickening properties). In addition, they are easily processed in different forms such as beads, films, capsules and fibres. Copyright © 2007 Society of Chemical Industry

Integrity signals

Registry

Crossref · 10.1002/pi.2378

Cites

521 of 521 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Cites

Flagged first, then by citations

6 of the 527 references couldn’t be matched to a known paper.

Cited by

Sorted by citations

Authors
Rinaudo, M.
Affiliations
Centre National de la Recherche Scientifique (FR)
Corresponding author
Rinaudo, Marguerite
Venue
Polymer International
Publisher
Wiley
Published
2007-10-09
Volume
57
Issue
3
Pages
397-430
ISSN
  • 0959-8103 (ISSN-L)
  • 1097-0126
OpenAlex
W2021252942
Cited by
1,028
References
527
Citations by year
2026: 45 · 2025: 51 · 2024: 50 · 2023: 64 · 2022: 63 · 2021: 67 · 2020: 87 · 2019: 58 · 2018: 55 · 2017: 68 · 2016: 62 · 2015: 59 · 2014: 70 · 2013: 58 · 2012: 51
FWCI
39.52
Type
journal article
Language
en
Open access
closed
Locations
  • Polymer International (publishedVersion)
  • HAL (submittedVersion)
Topics
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Polysaccharides Composition and Applications
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Medicine › Hydrogels: synthesis, properties, applications
  • Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmaceutical Science › Advanced Drug Delivery Systems
Keywords
polysaccharides, biomaterials, chitin, chitosan, hyaluronic acid, alginate, carrageenan, seaweed polysaccharides, physical gels, thermoreversible gels, electrostatic complexes, chitosan-alginate, encapsulation, biocompatibility, biodegradability, polysaccharide modification, film-forming properties, thickening properties, bio-based polymers

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review