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A revised set of potentials for β‐turn formation in proteins

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Hutchinson, E. Gail, Thornton, Janet M.·1994·Protein Science

Abstract

Three thousand eight hundred ninety‐nine β‐turns have been identified and classified using a nonhomologous data set of 205 protein chains. These were used to derive β‐turn positional potentials for turn types I' and II' for the first time and to provide updated potentials for formation of the more common types I, II, and VIII. Many of the sequence preferences for each of the 4 positions in turns can be rationalized in terms of the formation of stabilizing hydrogen bonds, preferences for amino acids to adopt a particular conformation in ϕ, ψ space, and the involvement of turn types I' and II' in β‐hairpins. Only 1,632 (42%) of the turns occur in isolation; the remainder have at least 1 residue in common with another turn and have hence been classified as multiple turns. Several types of multiple turn have been identified and analyzed.

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Metadata

Authors
Hutchinson, E. G., & Thornton, J. M.
Venue
Protein Science
Publisher
Wiley
Published
1994-12
Volume
3
Issue
12
Pages
2207-2216
ISSN
  • 0961-8368 (ISSN-L)
  • 1469-896X
OpenAlex
W2074655761
Cited by
937
References
3
FWCI
5.88
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: A revised set of potentials for β‐turn formation in proteins. https://app.cochat.ai/papers/10.1002/pro.5560031206
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Hutchinson, E. G., & Thornton, J. M. (1994). A revised set of potentials for β‐turn formation in proteins. Protein Science. https://doi.org/10.1002/pro.5560031206

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.