High level PSMA expression is associated with early PSA recurrence in surgically treated prostate cancer

Minner, Sarah, Wittmer, Corinna, Graefen, Markus, Salomon, Georg, Steuber, Thomas, Haese, Alexander, Huland, Hartwig, Bokemeyer, Carsten +8 more·2011·The Prostate

DOI 10.1002/pros.21241

Cited by (285)

Items 201–285 of 285

Immunohistochemical Prostate-specific Membrane Antigen (PSMA) Expression Patterns of Primary Prostate Cancer Tissue as a Determining Factor for Prostate Cancer Staging with PSMA Positron Emission Tomography/Computed Tomography
Francesca Ambrosini, Nataniele Piol, Matteo Bauckneht, Giovanni Drocchi, Benedetta Col, Marco Martiriggiano, Enrico Vecchio, Calogero Paola, Bruno Spina, Luca Sofia et al. · 2025 · European Urology Oncology
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Angela Y. Jia, Ana P. Kiess, Qiubai Li, Emmanuel S. Antonarakis · 2023 · Prostate Cancer and Prostatic Diseases
Prostate-Specific Membrane Antigen (PSMA) Expression Predicts Need for Early Treatment in Prostate Cancer Patients Managed with Active Surveillance
Elham Ahmadi, Simon Wang, Mohammad Gouran‐Savadkoohi, Georgia Douvi, Naghmeh Isfahanian, Nicole Tsakiridis, Brent E. Faught, Jean‐Claude Cutz, Monalisa Sur, Satish Chawla et al. · 2023 · International Journal of Molecular Sciences
Determining the optimal pharmacokinetic modelling and simplified quantification method of [18F]AlF-P16-093 for patients with primary prostate cancer (PPCa)
Ruiyue Zhao, Zeheng Xia, Ke Miao, Jie Lv, Huizhen Zhong, Yulu He, Di Gu, Yongda Liu, Guohua Zeng, Lin Zhu et al. · 2024 · European Journal of Nuclear Medicine and Molecular Imaging
Diagnostic Performance of 68Ga-PSMA-11 Positron-emission-tomography/Computed-tomography in a Large Cohort of Patients with Biochemical Recurrence of Prostate Carcinoma
Manuela A. Hoffmann, Hans‐Georg Buchholz, Helmut J. Wieler, Jonas Müller-Hübenthal, Ludwin Trampert, Ines Richardsen, Mathias Schreckenberger · 2020 · Health Physics
Prostate specific membrane antigen positron emission tomography/computed tomography and staging high risk prostate cancer: a non-systematic review of high clinical impact literature
Joshua James Morigi, Jack ANDERSON, Cosimo De Nunzio, Stefano Fanti · 2021 · Minerva Urology and Nephrology
Organ and tumour dosimetry of 177Lu-rhPSMA-10.1, a novel PSMA-targeted therapy: results from a Phase I trial
James Nagarajah, Hyun Kim, Luke T. Nordquist, Vikas Prasad, Nathaniel Scott, Daniel J. Stevens, Benjamin Fongenie, Joseph R. Osborne · 2025 · European Journal of Nuclear Medicine and Molecular Imaging
Adverse events associated with Lutetium-177-PSMA-617 (Pluvicto®) in advanced prostate cancer: a disproportionality analysis based on the fda’s adverse event reporting system (FAERS)
Yongchen Jin, Yishan Zhang, Mingshuai Wang, Xiaoxuan Bai, Hao Ping, Nianzeng Xing · 2025 · BMC Cancer
The use of advanced imaging in guiding the further investigation and treatment of primary prostate cancer
Heying Duan, Andrei H. Iagaru · 2022 · Cancer Imaging
Radiopharmaceuticals in Oncology
Jeroen A. C. M. Goos, Outi M. Keinänen, Brian M. Zeglis, Jason Stuart Lewis · 2020 · Wiley eBooks
Whole-body tumour burden on [18F]DCFPyL PET/CT in biochemical recurrence of prostate cancer: association with tumour biology and PSA kinetics
Laura García Zoghby, Mariano Amo‐Salas, Á.M. Soriano Castrejón, Ana María García Vicente · 2024 · European Journal of Nuclear Medicine and Molecular Imaging
Tropism and transduction of oncolytic adenovirus vectors in prostate cancer therapy
Chuang Wu, Fukun Wei, Ziyang Xu, Ru-min Wen, Jiacun Chen, Junqi Wang, Lijun Mao · 2021 · Frontiers in Bioscience-Landmark
[ 177 Lu]-PSMA-617 radionuclide therapy in patients with metastatic castration-resistant prostate cancer
Thorsten Derlin, Sebastian Schmuck · 2018 · The Lancet Oncology
The Performance and Role of PSMA PET Scans in Localised Prostate Cancer
Jianliang Liu, Jack Dunne, Karim A. Touijer, Marlon Perera, Nathan Lawrentschuk · 2025 · Société Internationale d’Urologie Journal
Navigating discordant findings in multimodality imaging of prostate cancer in the MRI and PSMA-PET era
Sungmin Woo, Benedetta Masci, Anton S. Becker, Angela Y. Tong, Kent P Friedman, Felipe de Galiza Barbosa, Damiano Caruso, Andrea Laghi, Hebert Alberto Vargas · 2025 · La radiologia medica
An Analysis of the Diagnostic Performance of Tc-99m PSMA SSPECT/CT in Biochemically Recurrent Prostate Cancer Compared with Ga-68 PSMA PET/CT: A Single-center, Prospective Study
Manish Ora, Vivek Kumar Saini, Manish Dixit, Uday Pratap Singh, Sanjay Gambhir · 2024 · Indian Journal of Nuclear Medicine
[18F]FDG and [68Ga]Ga-PSMA dual-tracer total-body PET/CT and PET/MR in patients with prostate cancer
Yu Lin, Huaping Gao, Yunze Xie, Hongcheng Shi · 2025 · The Quarterly Journal of Nuclear Medicine and Molecular Imaging
Time point-independent tumor positivity of 68Ga-PSMA-PET/CT pre- and post-biopsy in high-risk prostate cancer
Sijuan Zou, Shuang Song, Jianyuan Zhou, Bo Yu, Dong Kuang, Zhihua Wang, Xiaohua Zhu · 2022 · Annals of Nuclear Medicine
Confirmation of PSMA expression measured on [68Ga]Ga-PSMA PET/CT by immunohistochemistry in prostate adenocarcinoma
Tarık Şengöz, Nilay Şen Türk, Yusuf Özlülerden, Sinan Çelen, Aziz Gültekin, Olga Yaylalı, Doğangün Yüksel · 2023 · Nuclear Medicine Review
Effect of 18F-DCFPyL PET on changes in management of patients with prostate cancer: a systematic review and meta-analysis
Hui Wang, HongMei Zhu, GuanNan Li, JiaoNa Dai, HeXiao Huang, Qiong Jia · 2024 · Frontiers in Medicine
Microparticle Encapsulation of a Prostate-targeted Biologic for the Treatment of Liver Metastases in a Preclinical Model of Castration-resistant Prostate Cancer
Oliver C. Rogers, Lizamma Antony, Oren Levy, Nitin Joshi, Brian Wesley Simons, Susan L. Dalrymple, D. Marc Rosen, Andrew J. Pickering, Haoyue Lan, Heidi Kuang et al. · 2020 · Molecular Cancer Therapeutics
How prostate-specific membrane antigen level may be correlated with stemness in prostate cancer stem cell-like cell populations?
Ioannis Papasotiriou, Maria Toloudi, Panagiotis Apostolou, Marina Chatziioannou, Eleni Kourtidou, Ioanna Vlachou, Mimikakou Georgia · 2014 · Journal of Cancer Research and Therapeutics
Synthesis and Binding of a Novel PSMA-specific Conjugate
A. Holmberg, Marcela Márquez, Lena Lennartsson, Lennart Meurling, Sten F. Nilsson · 2018 · Anticancer Research
Comparison of staging using [68Ga]Ga-PSMA-11 PET/CT and histopathological results in intermediate- and high-risk prostate cancer patients treated with radical prostatectomy and pelvic lymph node dissection
Juan José Rosales, Vicky Betech-Antar, Fernando Mínguez, Félix Pareja, Fernando Guillén, Elena Prieto, Gemma Quincoces, Fernando Caballero, Bernardino Miñana López, José Luis Perez‐Gracia et al. · 2024 · Revista Española de Medicina Nuclear e Imagen Molecular (English Edition)
A Novel PSMA/FAP-Specific Radiotracer 99mTc-HFaPSMA for Diagnosis of PSMA-Negative Prostate Cancer: From Preclinical Validation to Clinical Translation
Yuchen Wang, Xinru Li, Chenzhen Li, Huiyuan Xing, Rui Gao, Bing Jia · 2025 · Journal of Medicinal Chemistry
Eficacia de la imagen precoz con 68Ga-PSMA-I&T para la discriminación de lesiones en los pacientes con cáncer de próstata
Filiz Özülker · 2018 · Revista Española de Medicina Nuclear e Imagen Molecular
Nieuwe beeldvormende technieken bij de diagnostiek van het prostaatcarcinoom
Daniela E. Oprea‐Lager, Emile F.I. Comans · 2019 · Tijdschrift voor Urologie
Medicinal (Radio) Chemistry: Building Radiopharmaceuticals for the Future
Martha Sahylí Ortega Pijeira, Paulo Sérgio Gonçalves Nunes, Samila Leon Chaviano, Aida Mary Abreu Diaz, Jean N. DaSilva, Eduardo Ricci‐Júnior, Luciana Magalhães Rebêlo Alencar, Xiaoyuan Shawn Chen, Ralph Santos‐Oliveira · 2023 · Current Medicinal Chemistry
PSMA-Ligand Imaging in the Diagnosis of Prostate Cancer
Ali Afshar‐Oromieh · 2020 · Springer eBooks
Qualitative and Quantitative Requirements for Assessing Prognostic Markers in Prostate Cancer
Christoph M. Burdelski, Aleksandra Matuszewska‐Janica, Martina Kluth, Christina Koop, Katharina Grupp, Stefan A. Steurer, Corinna Wittmer, Sarah Jane Pauline Minner, Maria Tsourlakis, Guido Sauter et al. · 2014 · Microarrays
[68Ga]PSMA-PET/CT-imaging bij de diagnostiek van prostaatkanker
André N. Vis, Bernard H. E. Jansen, Daniela E. Oprea‐Lager · 2017 · Tijdschrift voor Urologie
Theranostics in prostate cancer
Rainer W. Lipp · 2022 · memo - Magazine of European Medical Oncology
Near Complete Response to 177Lu-PSMA-DKFZ-617 Therapy in a Patient with Metastatic Castration Resistant Prostate Cancer
Madhav Prasad Yadav, Sanjana Ballal, Chandrasekhar Bal · 2017 · Journal of Radiology and Oncology
Does total lesion prostate‐specific membrane antigen (PSMA) activity on 68Ga‐PSMA PET/CT correlate with PSA and prostatectomy histopathological/clinical outcomes in patients with localised primary prostate cancer?
Jeremy Cheng, Mohammadmehdi Adhami, Tho Pham, David P. Nadebaum, Ashley Baring, Eldho Mathew Paul, Martin H. Cherk, Jeremy Grummet · 2025 · BJUI Compass
From conventional therapy to novel nano-based approaches. A focus on prostate cancer
Lorenzo Chiaverini, Giarita Ferraro, Riccardo Di Leo, Elisabetta Barresi, Diego La Mendola, Francesco Bartoli, Luca Famlonga, Cristina Satriano, Pinuccia Faviana, Alessandro Zucchi et al. · 2025 · Nanomedicine
Prognostic role of high MTAP expression is reversed by the ERG status in prostate cancer treated by radical prostatectomy
Natalia Gorbokon, Şeyma Büyücek, Henning Plage, Neele Heckmann, Ronald Simon, Maximilian Lennartz, Martina Kluth, Katharina Teljuk, Claudia Hube‐Magg, Sarah Jane Pauline Minner et al. · 2025 · Neoplasia
Diagnosis and Staging of Patients with Prostate Cancer: Report from the 2025 Advanced Prostate Cancer Consensus Conference (APCCC) Diagnostics
Stefano Fanti, Fabio Turco, Bertrand F. TOMBAL, Jochen Christoph Walz, Michael S. Hofman, Boris Alexander Hadaschik, Louise Emmett, Derya Tilki A, Giovanna Pecoraro, Giuseppe Salfi et al. · 2026 · European Urology
Adipose triglyceride lipase driven lipolysis as a targetable metabolic vulnerability in prostate cancer with intrinsic metabolic inflexibility
Andreas Tiefenbacher, Madeleine Gudenus, Daniel Valcanover, Barbara Neudert, Raheleh Sheibani‐Tezerji, Theresa Mendrina, Jessica Kalla, Laura Pajed, Kristina Draganić, Andrea Haitel et al. · 2026 · British Journal of Cancer
Verbesserte Diagnostik beim Prostatakarzinom: PSMA-PET
Benedikt Kranzbühler, Irene Andrea Burger, DANIEL MAX SCHMID, Tullio Sulser, Philipp Antonio Kaufmann, Daniel Eberli · 2016 · Swiss Medical Forum ‒ Schweizerisches Medizin-Forum
Efficacy of early imaging with 68Ga-PSMA I&T in the discrimination of pelvic lesions in prostate cancer patients
Filiz Özülker · 2018 · Revista Española de Medicina Nuclear e Imagen Molecular (English Edition)
Study of Immunohistochemical Marker Psma and Ki 67 Expression and Its Relation with Grading in Prostate Carcinoma
Amit V. Varma, Seema Jindal, Bela Sharda, Kamal Kumar Malukani, Shilpi Dosi, Pooja Kesharwani · 2022 · annals of urologic oncology
Predictors of Metastasis in 68GA-Prostate Specific Membrane Antigen Pet-CT in the Primary Staging of Prostate Cancer
Erkin Karaca, Erdem Kısa, Mehmet Çağlar Çakıcı, Taha Çetin, Mehmet Yiğit Yalçın, Mert Hamza Özbilen, Çağdaş Bildirici, Gökhan Koç · 2024 · Journal of Clinical Medicine
Physikalisch-technische Grundlagen und Tracerentwicklung in der Positronenemissionstomografie
Gerhard Glatting, Carmen Wängler, Björn Wängler · 2016 · Springer eBooks
Preoperative PSMA‐targeted PET imaging: more than just a tool for prostate cancer staging?
Alexa R. Meyer, Steven P. Rowe, Michael A. Gorin · 2019 · British Journal of Urology
Befundbericht zu Prostatastanzbiopsien – was Pathologen liefern und Urologen wollen
Anne Offermann, Marie Christine Hupe, Vincent Joerg, Verena Wilbeth Sailer, Mario W. Kramer, Axel S. Merseburger, Lars Tharun, Sven Perner · 2020 · Der Urologe
Precise Detection and Transcriptomic Concordant Analysis of Circulating Tumor Cells from Prostate Cancer
Hyungseok Cho, Ki-Ho Han, Jae‐Seung Chung, Seok‐Soo Byun, Jae Il Chung, Won Ik Seo, Chan Ho Lee · 2023 · Preprints.org
PSMAx-Guided PROTAC Degraders for Tumor-Specific Protein Degradation in Prostate Cancer
Xiao-Lei Meng, Xiaolin Hu, Siqi Zhang, Sai Zhang, Xiao Wang, Shumin Ma, Chong Qin · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
Transcription-Based Molecular Imaging and Gene Therapy for Castration-resistant and Metastatic Prostate Cancer in Translational Models
Ziyue Karen Jiang · 2013 · eScholarship (California Digital Library)
177Lu-PSMA-Radioligandentherapie beim fortgeschrittenen Prostatakarzinom
Thorsten Derlin · 2017 · Der Radiologe
Prostate Cancer Microparticles in Men Undergoing Radical Prostatectomy
Malcolm Dewar · 2017 · Scholarship@Western (Western University)
Radiothérapie interne vectorisée par 177Lu-PSMA-617 de l’adénocarcinome prostatique métastatique résistant à la castration : à propos d’un cas et revue de la littérature
Léa Turpin, Marie Calzada-Nocaudie, Jules Tianyu Zhang-Yin, Timofei Rusu, A. Dumont Bruzek, Cyrielle Aveline, B. Sgard, V. Nataf, Olivier Cussenot, Françoise Montravers et al. · 2019 · Médecine Nucléaire
Targets, Tracers and Translation – Novel Radiopharmaceuticals Boost Nuclear Medicine
Gerald Reischl · 2019 · MDPI eBooks
99MTc-PSMA – radionuclide imaging of prostate cancer: an innovative diagnostic direction in nuclear medicine
P.O. Korol, Mikhail N. Tkachenko, A. Voloshin · 2020 · Radiation Diagnostics Radiation Therapy
Prostate Specific Membrane Antigen Based Imaging
Murat Tuncel · 2021 · Springer eBooks
Testicular metastasis in prostate cancer: A rare case of testicular metastasis diagnosed with 68Ga-PSMA and review of the literature
Gökhan Özyiğit, Bülent Akdoğan, Melek Tuğçe Yılmaz, Güneş Güner, Murat Fani Bozkurt · 2022 · Journal of Clinical Urology
Advances in Prostate Cancer Imaging
Ali Aria Razmaria, Heiko M. Schöder, Michael J. Morris · 2022 · Springer eBooks
Die Expression des prostataspezifischen Membranantigens (PSMA) beim Mammakarzinom
C. Unger, Peter Bronsert, Kerstin Michalski, Anna Bicker, Ingolf Juhasz-Böss · 2022 · TumorDiagnostik & Therapie
Molecular Heterogeneity in Primary and Metastatic Prostate Tumor Tissue
Julie L. Batista · 2015 · Defense Technical Information Center (DTIC)
Expression of RNA-binding motif protein 3 is increased in gastric adenocarcinoma but unrelated to prognosis of patients
Nathaniel Melling, Faik Güntac Uzunoglu, Tarik Ghadban, Michael Tachezy, André Hajek, Jakob Robert Izbicki, Katharina Grupp · 2023 · Research Square
Radioligand Therapy of Patients with Metastatic Castrate-Resistant Prostate Cancer
Elena R. Nemtsova, Andrey A. Pankratov, N. B. Morozova, V. K. Tischenko, V. M. Petriev, В. В. Крылов, П. В. Шегай, С. А. Иванов, А. Д. Каприн · 2022 · Biology Bulletin
Data from In Vivo Imaging of Methionine Aminopeptidase II for Prostate Cancer Risk Stratification
Jinghang Xie, Meghan A. Rice, Zixin Chen, Yunfeng Cheng, En‐Chi Hsu, Min Chen, Guosheng Song, Liyang Cui, Kaixiang Zhou, Jessa B. Castillo et al. · 2023
Data from Cytoplasmic Localization of Prostate-Specific Membrane Antigen Inhibitors May Confer Advantages for Targeted Cancer Therapies
Jessica Matthias, Johann Engelhardt, Martin K.-H. Schäfer, Ulrike Bauder‐Wüst, Philipp Tobias Meyer, Uwe Haberkorn, Matthias Eder, Klaus Kopka, Stefan W. Hell, Ann-Christin Eder · 2023
PSMA-Directed Theragnostics: Transforming Prostate Cancer Landscape
Alex Friedlaender, Olivier Rager, Alexander Meisel · 2023 · healthbook TIMES Oncology Hematology
Real-World Outcomes Of Lu-177 PSMA In Patients With Metastatic Castration-Resistant Prostate Cancer: A Retrospective Single-Center Experience
Ebru Karcı, Sabin Göktaş Aydın, Ahmet Erkan Bilici, Tamer Atasever, Tansel Çakır, Ömer Fatih Ölmez, Özgür Açıkgöz, Yasin Kutlu, Özcan Yıldız · 2023 · Research Square
Metastatic castration-resistant prostate cancer therapy: the quest for the perfect molecule
Davide Bianco, Carmela Nappi, Michele Klain · 2023 · European Journal of Nuclear Medicine and Molecular Imaging
Desempenho do 68Ga-PSMA-11 PET/RM em comparação com a ressonância magnética multiparamétrica na biópsia de próstata guiada em pacientes com antígeno prostático específico elevado
Daniela Andrade Ferraro · 2024
Comparación de la estadificación mediante [68Ga]Ga-PSMA-11 PET/TC y los resultados anatomopatológicos en pacientes con cáncer de próstata de riesgo intermedio y alto tratados con prostatectomía radical y linfadenectomía pélvica
Juan José Rosales, Vicky Betech-Antar, Fernando Mínguez, F. Pareja, F. Guillén, E. Prieto, Gemma Quincoces, Fernando Caballero, B. Miñana, José Luis Perez‐Gracia et al. · 2024 · Revista Española de Medicina Nuclear e Imagen Molecular
Diagnostic Performance of PET-Based Targeted Fusion Biopsy in Prostate Cancer
Heying Duan, Pejman Ghanouni, Geoffrey A. Sonn, Andrei H. Iagaru · 2024 · Springer eBooks
Radionuklidtherapie 2025: Optionen der Nuklearmedizin in der Behandlung des metastasierten kastrationsresistenten Prostatakarzinoms
Luisa Willner, Robert Tauber, Matthias J. Eiber · 2025 · Die Urologie
Future Perspectives: Metabolic Imaging, Theranostics, and Radiomics
Jeffrey J. Peterson, Alexander D. Weston, Fatemeh Ataei · 2025 · Springer eBooks
Update Nuklearmedizin 2025: Theranostik
Ralph Alexander Bundschuh, Johanna S. Enke, Elena Brinkmann, Conrad‐Amadeus Voltin, Winfried Brenner · 2025 · Die Onkologie
Novel tetravalent bispecific antibody, PSMA/TRAIL‑R2 REGULGENT™, induces selective tumor cell apoptosis without hepatotoxicity
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Jana Pokorná, Martin Hadzima, Alena Křenková, Joshua D. Smith, Vladimír Šubr, Robin Kryštůfek, Martin Hubálek, Jana Starková, Karolína Šrámková, Tomáš Etrych et al. · 2025 · Scientific Reports
Additional file 1 of 68Ga-PSMA PET/CT-based multivariate model for highly accurate and noninvasive diagnosis of clinically significant prostate cancer in the PSA gray zone
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Additional file 1 of PSMA-ligand uptake can serve as a novel biomarker in primary prostate cancer to predict outcome after radical prostatectomy
Wang, Hui, Thomas Amiel, Christoph Würnschimmel, Thomas Langbein, Steiger, Katja, Isabel Rauscher, Horn, Thomas, Maurer, Tobias, Weber, Wolfgang, Wester, Hans-Juergen et al. · 2021 · Figshare
Additional file 1 of Heterogeneity of prostate-specific membrane antigen (PSMA) and PSMA-ligand uptake detection combining autoradiography and postoperative pathology in primary prostate cancer
Wang, Hui, Marianne Remke, Horn, Thomas, Kristina Schwamborn, Chen, Yiyao, Steiger, Katja, Wilko Weichert, Wester, Hans-Jürgen, Margret Schottelius, Weber, Wolfgang A. et al. · 2024 · Figshare
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Jules Tianyu Zhang-Yin · 2020
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Nino Jukic, Dražen Huić, Marijan Žuvić, Ivan Nemet, Sanda Rončević · 2026 · EJNMMI Radiopharmacy and Chemistry
TROP2 Is Uniformly Expressed in Primary Prostate Cancer but Frequently Reduced in Recurrent Disease
Jonathan Jeutner, Ronald Simon, Maximilian Lennartz, Sarah Jane Pauline Minner, Eike Burandt, Fiete Gehrisch, Nina Schraps, Martina Kluth, Guido Sauter, Henning Plage et al. · 2026 · Cancers
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Development and validation of a preoperative 18F-PSMA-1007 PET/MR prognostic model for predicting biochemical recurrence in prostate cancer: a multicentre study
Jiajia Hu, Hangxing Chunyu, Yihong Yang, Yanyan Song, Chao Cheng, Hailang Tang, Xiaoyue Chen, Ran Cheng, Jun Dai, Hongping Meng et al. · 2026 · European Journal of Nuclear Medicine and Molecular Imaging
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