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Critical assessment of methods of protein structure prediction—Round VII

Open access
Moult, John, Fidelis, Krzysztof, Kryshtafovych, Andriy, Rost, Burkhard, Hubbard, Tim, Tramontano, Anna·2007·Proteins: Structure, Function, and Bioinformatics

Abstract

This article is an introduction to the special issue of the journal Proteins, dedicated to the eighth CASP experiment to assess the state of the art in protein structure prediction. The article describes the conduct of the experiment, the categories of prediction included, and outlines the evaluation and assessment procedures. Highlights are the first blind assessment of model refinement methods showing that under some circumstances substantial model improvements are possible; improvements in the performance of methods for determining the accuracy of a model; and some progress in the accuracy of comparative models in regions not present in a principal template. Against these advances must be stacked the fact that there is no detectable progress in model quality compared with CASP7 in either template-based or template free modeling, using the established CASP measures.

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Metadata

Authors
Moult, J., Fidelis, K., Kryshtafovych, A., Rost, B., Hubbard, T., & Tramontano, A.
Venue
Proteins: Structure, Function, and Bioinformatics
Publisher
Wiley
Published
2007
Volume
69
Issue
S8
Pages
3-9
ISSN
  • 0887-3585 (ISSN-L)
  • 1097-0134
OpenAlex
W2089035513
Cited by
324
References
3
FWCI
17.84
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: Critical assessment of methods of protein structure prediction—Round VII. https://app.cochat.ai/papers/10.1002/prot.21767
The paper
Moult, J., Fidelis, K., Kryshtafovych, A., Rost, B., Hubbard, T., & Tramontano, A. (2007). Critical assessment of methods of protein structure prediction—Round VII. Proteins: Structure, Function, and Bioinformatics. https://doi.org/10.1002/prot.21767

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.