Cited by 72Sexual function and dysfunction studiesHormonal and reproductive studiesSperm and Testicular Function

Physiological Aspects of Male Libido Enhanced by Standardized Trigonella foenum‐graecum Extract and Mineral Formulation

Steels, Elizabeth, Rao, Amanda, Vitetta, Luis·2011·Phytotherapy Research

Abstract

The aim of the clinical study was to evaluate the effect of Testofen, a standardized Trigonella foenum-graecum (Fenugreek) extract and mineral formulation, on male libido (sexual drive, urge or desire) in a double blind randomized placebo controlled study. The study recruited 60 healthy males aged between 25 and 52, without erectile dysfunction and randomized to an oral dose (two tablets per day) of the active treatment (600 mg Testofen per day) or placebo for 6 weeks. The primary outcome measure was the DISF-SR (male) self-administered QOL total score and the four domain scores. The secondary outcome was specific quality of life parameters. Testofen had an overall positive effect on physiological aspects of libido. In particular, there was a significant increase in the subdomains of sexual arousal and orgasm. Testofen had a positive effect on QOL in self-reported satisfaction with muscle strength, energy and well-being but did not have an effect on mood or sleep. Serum prolactin and testosterone levels remained within the reference range. It was concluded that Testofen demonstrated a significant positive effect on physiological aspects of libido and may assist to maintain normal healthy testosterone levels.

Integrity signals

Registry

Crossref · 10.1002/ptr.3360

Cites

31 of 31 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • The clinical significance of the net benefit of herbal supplements is yet to be determined, with ambiguity regarding long-term safety.

    “Therefore, the clinical significance of this net benefit is yet to be determined, with ambiguity regarding long-term safety.[62][63][64][65][66][67][68][69][70][71][72][73]”

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Authors
Steels, E., Rao, A., & Vitetta, L.
Affiliations
  • Applied Science and Nutrition Pty Ltd, Clinical Trials Brisbane Australia
  • The University of Queensland (AU)
Corresponding author
Steels, Elizabeth
Venue
Phytotherapy Research
Publisher
Wiley
Published
2011-02-10
Volume
25
Issue
9
Pages
1294-1300
ISSN
  • 0951-418X (ISSN-L)
  • 1099-1573
OpenAlex
W2160697406
Cited by
71
References
31
Citations by year
2026: 3 · 2025: 4 · 2024: 2 · 2023: 7 · 2022: 4 · 2021: 7 · 2020: 10 · 2019: 6 · 2018: 4 · 2017: 7 · 2016: 7 · 2015: 5 · 2014: 3 · 2013: 2
FWCI
1.09
Type
journal article
Language
en
Open access
closed
Locations
  • Phytotherapy Research (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Sexual function and dysfunction studies
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Hormonal and reproductive studies
  • Health Sciences › Medicine › Reproductive Medicine › Sperm and Testicular Function
Keywords
fenugreek extract, fenugreek, male libido, sexual function, quality of life, sexual arousal, orgasm, testosterone, prolactin, healthy men
MeSH terms
Adult, Double-Blind Method, Humans, Libido, Magnesium, Male, Middle Aged, Plant Extracts, Prolactin, Pyridoxine, Quality of Life, Testosterone, Zinc, Patient Satisfaction, Trigonella

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review