The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Conformational changes in proteins probed by hydrogen‐exchange electrospray‐ionization mass spectrometry
Abstract
Hydrogen‐exchange electrospray‐ionization mass spectrometry is demonstrated to be an effective new method for probing conformational changes of proteins in solutions. The method is based on the mass spectrometric measurement of the extent of hydrogen/deuterium exchange that occurs in different protein conformers over defined periods of time. Results are presented in which hydrogen‐exchange electrospray‐ionization mass spectrometry is used to probe conformational changes in bovine ubiquitin induced by the addition of methanol to aqueous acidic solutions of the protein.
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Citations
Cites
Electrospray Ionization for Mass Spectrometry of Large Biomolecules
Fenn, J. B., Mann, M., Meng, C. K., Wong, S. F., & Whitehouse, C. M. (1989) · Science · doi:10.1126/science.2675315 · Cited by 7,634
Cited by
[21] Electrospray ionization mass spectrometry
Fred Banks, J., & Whitehouse, C. M. (1996) · Methods in Enzymology · doi:10.1016/s0076-6879(96)70023-x · Cited by 522
Gas-Phase Conformation of Biological Molecules: Bradykinin
Wyttenbach, T., von Helden, G., & Bowers, M. T. (1996) · Journal of the American Chemical Society · doi:10.1021/ja9535928 · Cited by 384
Ion/Ion Reactions in the Gas Phase: Proton Transfer Reactions Involving Multiply-Charged Proteins
Stephenson, J. L., & McLuckey, S. A. (1996) · Journal of the American Chemical Society · doi:10.1021/ja9611755 · Cited by 215
Wei, H., Mo, J., Tao, L., Russell, R. J., Tymiak, A. A., Chen, G., Iacob, R. E., & Engen, J. R. (2014) · Drug Discovery Today · doi:10.1016/j.drudis.2013.07.019 · Cited by 208
Surfactant effects on protein structure examined by electrospray ionization mass spectrometry
Loo, R. R. O., Dales, N., & Andrews, P. C. (1994) · Protein Science · doi:10.1002/pro.5560031109 · Cited by 184
Metadata
- Authors
- Katta, V., Chait, B. T., & Carr, S.
- Venue
- Rapid Communications in Mass Spectrometry
- Publisher
- Wiley
- Published
- 1991-04
- Volume
- 5
- Issue
- 4
- Pages
- 214-217
- ISSN
- 0951-4198 (ISSN-L)
- 1097-0231
- OpenAlex
- W2115463031
- Cited by
- 453
- References
- 1
- FWCI
- 12.80
- Type
- journal article
- Language
- en
- Open access
- closed
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- Katta, V., Chait, B. T., & Carr, S. (1991). Conformational changes in proteins probed by hydrogen‐exchange electrospray‐ionization mass spectrometry. Rapid Communications in Mass Spectrometry. https://doi.org/10.1002/rcm.1290050415
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
