The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Visual Cocaine Detection with Gold Nanoparticles and Rationally Engineered Aptamer Structures
Abstract
A novel bioassay strategy is designed to detect small‐molecule targets such as cocaine, potassium, and adenosine, based on gold nanoparticles (AuNPs) and engineered DNA aptamers. In this design, an aptamer is engineered to be two pieces of random, coil‐like single‐stranded DNA, which reassembles into the intact aptamer tertiary structure in the presence of the specific target. AuNPs can effectively differentiate between these two states via their characteristic surface‐plasmon resonance‐based color change. Using this method, cocaine in the low‐micromolar range is selectively detected within minutes. This strategy is also shown to be generic and applicable to the detection of several other small‐molecule targets.
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Cites
Nanostructures in Biodiagnostics
Rosi, N. L., & Mirkin, C. A. (2005) · Chemical Reviews · doi:10.1021/cr030067f · Cited by 4,603
Cited by
Gold Nanomaterials at Work in Biomedicine
Yang, X., Yang, M., Pang, B., Vara, M., & Xia, Y. (2015) · Chemical Reviews · doi:10.1021/acs.chemrev.5b00193 · Cited by 1,162
Optical aptasensors for quantitative detection of small biomolecules: A review
Feng, C., Dai, S., & Wang, L. (2014) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2014.03.014 · Cited by 300
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Metadata
- Authors
- Zhang, J., Wang, L., Pan, D., Song, S., Boey, F. Y. C., Zhang, H., & Fan, C.
- Venue
- Small
- Publisher
- Wiley
- Published
- 2008-07-31
- Volume
- 4
- Issue
- 8
- Pages
- 1196-1200
- ISSN
- 1613-6810 (ISSN-L)
- 1613-6829
- OpenAlex
- W2040345323
- Cited by
- 408
- References
- 1
- FWCI
- 13.03
- Type
- journal article
- Language
- en
- Open access
- closed
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- Zhang, J., Wang, L., Pan, D., Song, S., Boey, F. Y. C., Zhang, H., & Fan, C. (2008). Visual Cocaine Detection with Gold Nanoparticles and Rationally Engineered Aptamer Structures. Small. https://doi.org/10.1002/smll.200800057
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