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Biodistribution of 1.4‐ and 18‐nm Gold Particles in Rats
Abstract
1.4-nm gold nanoparticles (NPs) are observed to cross the air/blood barrier of the lungs much more efficiently than 18-nm gold NPs (see figure). The NP accumulation pattern in the secondary-target organs differs strongly from those seen after direct intravenous injection. From this, it is hypothesized that NPs interact dynamically with proteins and cells, which determines their accumulation in the various organs.
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Cited by
The Effect of Nanoparticle Size on In Vivo Pharmacokinetics and Cellular Interaction
Hoshyar, N., Gray, S., Han, H., & Bao, G. (2016) · Nanomedicine · doi:10.2217/nnm.16.5 · Cited by 1,990
Gold Nanomaterials at Work in Biomedicine
Yang, X., Yang, M., Pang, B., Vara, M., & Xia, Y. (2015) · Chemical Reviews · doi:10.1021/acs.chemrev.5b00193 · Cited by 1,162
Deposition and biokinetics of inhaled nanoparticles
Geiser, M., & Kreyling, W. G. (2010) · Particle and Fibre Toxicology · doi:10.1186/1743-8977-7-2 · Cited by 747
Self-citationGold nanoparticles: opportunities and challenges in nanomedicine
Arvizo, R., Bhattacharya, R., & Mukherjee, P. (2010) · Expert Opinion on Drug Delivery · doi:10.1517/17425241003777010 · Cited by 538
Luminescent Gold Nanoparticles with Efficient Renal Clearance
Zhou, C., Long, M., Qin, Y., Sun, X., & Zheng, J. (2011) · Angewandte Chemie International Edition · doi:10.1002/anie.201007321 · Cited by 490
Metadata
- Authors
- Semmler‐Behnke, M., Kreyling, W. G., Lipka, J., Fertsch, S., Wenk, A., Takenaka, S., Schmid, G., & Brandau, W.
- Venue
- Small
- Publisher
- Wiley
- Published
- 2008-12
- Volume
- 4
- Issue
- 12
- Pages
- 2108-2111
- ISSN
- 1613-6810 (ISSN-L)
- 1613-6829
- OpenAlex
- W2106600662
- Cited by
- 501
- References
- 0
- FWCI
- 13.69
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Biodistribution of 1.4‐ and 18‐nm Gold Particles in Rats. https://app.cochat.ai/papers/10.1002/smll.200800922
- The paper
- Semmler‐Behnke, M., Kreyling, W. G., Lipka, J., Fertsch, S., Wenk, A., Takenaka, S., Schmid, G., & Brandau, W. (2008). Biodistribution of 1.4‐ and 18‐nm Gold Particles in Rats. Small. https://doi.org/10.1002/smll.200800922
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
