The DOI matches its Crossref record; 94 of the 94 references it cites were found in a registry or an index.
Gold nanoparticles: opportunities and challenges in nanomedicine
Open accessAbstract
IMPORTANCE OF THE FIELD: Site-specific drug delivery is an important area of research that is anticipated to increase the efficacy of the drug and reduce potential side effects. Owing to this, substantial work has been done developing non-invasive and targeted tumor treatment with nanoscale metallic particles. AREAS COVERED IN THIS REVIEW: This review focuses on the work done in the last few years developing gold nanoparticles as cancer therapeutics and diagnostic agents. However, there are challenges in using gold nanoparticles as drug delivery systems, such as biodistribution, pharmacokinetics and possible toxicity. Approaches to limit these issues are proposed. WHAT THE READER WILL GAIN: Different approaches from several different disciplines are discussed. Potential clinical applications of these engineered nanoparticles are also presented. TAKE HOME MESSAGE: As a result of their unique size-dependent physicochemical and optical properties, adaptability, subcellular size and biocompatibility, these nanosized carriers offer a suitable means of transporting small molecules as well as biomacromolecules to diseased cells/tissues.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Jemal, A., Siegel, R., Ward, E., Hao, Y., Xu, J., & Thun, M. J. (2009) · CA: A Cancer Journal for Clinicians · doi:10.3322/caac.20006 · Cited by 9,709
Nanocarriers as an emerging platform for cancer therapy
Peer, D., Karp, J. M., Hong, S., Farokhzad, O. C., Margalit, R., & Langer, R. (2007) · Nature Nanotechnology · doi:10.1038/nnano.2007.387 · Cited by 8,710
Semiconductor Nanocrystals as Fluorescent Biological Labels
Bruchez, M., Moronne, M., Gin, P., Weiss, S., & Alivisatos, A. P. (1998) · Science · doi:10.1126/science.281.5385.2013 · Cited by 8,613
Controlled Nucleation for the Regulation of the Particle Size in Monodisperse Gold Suspensions
FRENS, G. (1973) · Nature Physical Science · doi:10.1038/physci241020a0 · Cited by 8,336
A study of the nucleation and growth processes in the synthesis of colloidal gold
Turkevich, J., Stevenson, P. C., & Hillier, J. (1951) · Discussions of the Faraday Society · doi:10.1039/df9511100055 · Cited by 7,792
Quantum Dot Bioconjugates for Ultrasensitive Nonisotopic Detection
Chan, W. C. W., & Nie, S. (1998) · Science · doi:10.1126/science.281.5385.2016 · Cited by 7,278
Chemistry and Properties of Nanocrystals of Different Shapes
Burda, C., Chen, X., Narayanan, R., & El-Sayed, M. A. (2005) · Chemical Reviews · doi:10.1021/cr030063a · Cited by 7,230
Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
Hanahan, D., & Folkman, J. (1996) · Cell · doi:10.1016/s0092-8674(00)80108-7 · Cited by 6,885
Matsumura, Y., & Maeda, H. (1986) · PubMed · Cited by 6,781
Synthesis of thiol-derivatised gold nanoparticles in a two-phase Liquid–Liquid system
Brust, M., Walker, M., Bethell, D., Schiffrin, D. J., & Whyman, R. (1994) · J. Chem. Soc., Chem. Commun. · doi:10.1039/c39940000801 · Cited by 6,707
Cited by
Gold nanoparticles for applications in cancer radiotherapy: Mechanisms and recent advancements
Her, S., Jaffray, D. A., & Allen, C. (2017) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2015.12.012 · Cited by 865
Nanomedicine therapeutic approaches to overcome cancer drug resistance
Markman, J. L., Rekechenetskiy, A., Holler, E., & Ljubimova, J. Y. (2013) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2013.09.019 · Cited by 733
“Sodium citrate can also be used as a reducing agent for gold formation, and a stabilizer to avoid aggregation during synthesis [13].”
BackgroundA Review on the Synthesis and Functionalization of Gold Nanoparticles as a Drug Delivery Vehicle
Amina, S. J., & Guo, B. (2020) · International Journal of Nanomedicine · doi:10.2147/ijn.s279094 · Cited by 561
Multidrug Resistance (MDR): A Widespread Phenomenon in Pharmacological Therapies
Catalano, A., Iacopetta, D., Ceramella, J., Scumaci, D., Giuzio, F., Saturnino, C., Aquaro, S., Rosano, C., & Sinicropi, M. S. (2022) · Molecules · doi:10.3390/molecules27030616 · Cited by 450
Role of Nanotechnology in Cosmeceuticals: A Review of Recent Advances
Kaul, S., Gulati, N., Verma, D., Mukherjee, S., & Nagaich, U. (2018) · Journal of Pharmaceutics · doi:10.1155/2018/3420204 · Cited by 435
Metadata
- Authors
- Arvizo, R., Bhattacharya, R., & Mukherjee, P.
- Venue
- Expert Opinion on Drug Delivery
- Publisher
- Informa Healthcare
- Published
- 2010-04-21
- Volume
- 7
- Issue
- 6
- Pages
- 753-763
- ISSN
- 1742-5247 (ISSN-L)
- 1744-7593
- OpenAlex
- W2020525105
- Cited by
- 538
- References
- 94
- FWCI
- 6.84
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Gold nanoparticles: opportunities and challenges in nanomedicine. https://app.cochat.ai/papers/10.1517/17425241003777010
- The paper
- Arvizo, R., Bhattacharya, R., & Mukherjee, P. (2010). Gold nanoparticles: opportunities and challenges in nanomedicine. Expert Opinion on Drug Delivery. https://doi.org/10.1517/17425241003777010
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
