The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Gold Nanoparticles Downregulate Interleukin‐1β‐Induced Pro‐Inflammatory Responses
Abstract
Interleukin 1 beta (IL‐1β)‐dependent inflammatory disorders, such as rheumatoid arthritis and psoriasis, pose a serious medical burden worldwide, where patients face a lifetime of illness and treatment. Organogold compounds have been used since the 1930s to treat rheumatic and other IL‐1β‐dependent diseases and, though their mechanisms of action are still unclear, there is evidence that gold interferes with the transmission of inflammatory signalling. Here we show for the first time that citrate‐stabilized gold nanoparticles, in a size dependent manner, specifically downregulate cellular responses induced by IL‐1β both in vitro and in vivo. Our results indicate that the anti‐inflammatory activity of gold nanoparticles is associated with an extracellular interaction with IL‐1β, thus opening potentially novel options for further therapeutic applications.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Yazdi, A. S., Guarda, G., Riteau, N., Drexler, S. K., Tardivel, A., Couillin, I., & Tschopp, J. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1008155107 · Cited by 525
Sumbayev, V. V. (2008) · FEBS Letters · doi:10.1016/j.febslet.2007.12.024 · Cited by 62
Self-citation
Cited by
Gold Nanoparticles for Photothermal Cancer Therapy
Vines, J. B., Yoon, J.-H., Ryu, N.-E., Lim, D.-J., & Park, H. (2019) · Frontiers in Chemistry · doi:10.3389/fchem.2019.00167 · Cited by 906
Various methods of gold nanoparticles (GNPs) conjugation to antibodies
Jazayeri, M. H., Amani, H., Pourfatollah, A. A., Pazoki-Toroudi, H., & Sedighimoghaddam, B. (2016) · Sensing and Bio-Sensing Research · doi:10.1016/j.sbsr.2016.04.002 · Cited by 528
Recent applications of immunomodulatory biomaterials for disease immunotherapy
Dai, H., Fan, Q., & Wang, C. (2022) · Exploration · doi:10.1002/exp.20210157 · Cited by 268
Han, J., Kim, Y. S., Lim, M.-Y., Kim, H. Y., Kong, S., Kang, M., Choo, Y. W., Jun, J. H., Ryu, S., Jeong, H.-Y., et al. (2018) · ACS Nano · doi:10.1021/acsnano.7b09107 · Cited by 258
Metadata
- Authors
- Sumbayev, V. V., Yasinska, I. M., Garcia, C. P., Gilliland, D., Lall, G. S., Gibbs, B. F., Bonsall, D. R., Varani, L., Rossi, F., & Calzolai, L.
- Venue
- Small
- Publisher
- Wiley
- Published
- 2012-10-30
- Volume
- 9
- Issue
- 3
- Pages
- 472-477
- ISSN
- 1613-6810 (ISSN-L)
- 1613-6829
- OpenAlex
- W2154809330
- Cited by
- 210
- References
- 2
- FWCI
- 2.55
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Gold Nanoparticles Downregulate Interleukin‐1β‐Induced Pro‐Inflammatory Responses. https://app.cochat.ai/papers/10.1002/smll.201201528
- The paper
- Sumbayev, V. V., Yasinska, I. M., Garcia, C. P., Gilliland, D., Lall, G. S., Gibbs, B. F., Bonsall, D. R., Varani, L., Rossi, F., & Calzolai, L. (2013). Gold Nanoparticles Downregulate Interleukin‐1β‐Induced Pro‐Inflammatory Responses. Small. https://doi.org/10.1002/smll.201201528
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
