The DOI matches its Crossref record; 218 of the 218 references it cites were found in a registry or an index.
Recent applications of immunomodulatory biomaterials for disease immunotherapy
Open accessAbstract
Immunotherapy is used to regulate systemic hyperactivation or hypoactivation to treat various diseases. Biomaterial‐based immunotherapy systems can improve therapeutic effects through targeted drug delivery, immunoengineering, etc. However, the immunomodulatory effects of biomaterials themselves cannot be neglected. In this review, we outline biomaterials with immunomodulatory functions discovered in recent years and their applications in disease treatment. These biomaterials can treat inflammation, tumors, or autoimmune diseases by regulating immune cell function, exerting enzyme‐like activity, neutralizing cytokines, etc. The prospects and challenges of biomaterial‐based modulation of immunotherapy are also discussed.
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Hoffmann, M., Kleine-Weber, H., Schroeder, S., Krüger, N., Herrler, T., Erichsen, S., Schiergens, T. S., Herrler, G., Wu, N.-H., Nitsche, A., et al. (2020) · Cell · doi:10.1016/j.cell.2020.02.052 · Cited by 20,286
The biology , function , and biomedical applications of exosomes
Kalluri, R., & LeBleu, V. S. (2020) · Science · doi:10.1126/science.aau6977 · Cited by 10,770
Nanomaterials with enzyme-like characteristics (nanozymes): next-generation artificial enzymes (II)
Wu, J., Wang, X., Wang, Q., Lou, Z., Li, S., Zhu, Y., Qin, L., & Wei, H. (2019) · Chemical Society Reviews · doi:10.1039/c8cs00457a · Cited by 4,108
Nanomaterials with enzyme-like characteristics (nanozymes): next-generation artificial enzymes
Wei, H., & Wang, E. (2013) · Chemical Society Reviews · doi:10.1039/c3cs35486e · Cited by 3,779
Advances in engineering hydrogels
Zhang, Y. S., & Khademhosseini, A. (2017) · Science · doi:10.1126/science.aaf3627 · Cited by 2,908
Mesoporous Silica Nanoparticles: Synthesis, Biocompatibility and Drug Delivery
Tang, F., Li, L., & Chen, D. (2012) · Advanced Materials · doi:10.1002/adma.201104763 · Cited by 2,836
Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response
Chen, G., Huang, A. C., Zhang, W., Zhang, G., Wu, M., Xu, W., Yu, Z., Yang, J., Wang, B., Sun, H., et al. (2018) · Nature · doi:10.1038/s41586-018-0392-8 · Cited by 2,813
Gold nanoparticles in delivery applications☆
GHOSH, P., HAN, G., DE, M., KIM, C., & ROTELLO, V (2008) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2008.03.016 · Cited by 2,694
Pegtel, D. M., & Gould, S. J. (2019) · Annual Review of Biochemistry · doi:10.1146/annurev-biochem-013118-111902 · Cited by 2,682
Concise review: MSC-derived exosomes for cell-free therapy
Phinney, D. G., & Pittenger, M. F. (2017) · Stem Cells · doi:10.1002/stem.2575 · Cited by 1,834
Cited by
Xu, Q., Zhang, M., Huang, Q., Gao, S., Chu, S., Li, Q., Chen, W., Zhang, X., Zhang, T., Tang, B. Z., et al. (2025) · Advanced Materials · doi:10.1002/adma.202502898 · Cited by 69
Metadata
- Authors
- Dai, H., Fan, Q., & Wang, C.
- Venue
- Exploration
- Publisher
- Wiley
- Published
- 2022-05-23
- Volume
- 2
- Issue
- 6
- Pages
- 20210157-20210157
- ISSN
- 2766-2098 (ISSN-L)
- OpenAlex
- W4281285769
- Cited by
- 268
- References
- 218
- FWCI
- 18.50
- Type
- journal article
- Language
- en
- Open access
- gold
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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