The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Titanium Incorporation into Zr‐Porphyrinic Metal–Organic Frameworks with Enhanced Antibacterial Activity against Multidrug‐Resistant Pathogens
Abstract
This study uses metal–organic frameworks (MOFs) alone without any added antibacterial ingredients as the nonantibiotic agent for photodynamic therapy (PDT) of chronic wounds infected by multidrug‐resistant (MDR) bacteria. Nanoparticles (NPs) of MOFs (PCN‐224) are incorporated with titanium through a facile cation exchange strategy. The obtained bimetallic PCN‐224(Zr/Ti) shows greatly enhanced photocatalytic performance for the generation of reactive oxygen species under visible light, which is responsible for the effective antibacterial activities. The PCN‐224(Zr/Ti) NPs are loaded onto lactic‐co‐glycolic acid nanofibers to prepare a wound dressing, which shows high biocompatibility and minimal cytotoxicity. The wound dressing is efficient for PDT‐based in vivo healing of the chronic wound infected by MDR bacteria. Most importantly, this work does not involve any additional antibacterial agents, which is facile, low cost, and in particular, greatly explores the potential of MOFs as a powerful nonantibiotic agent in PDT.
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Cites
Opal, S. M., & DePalo, V. A. (2000) · Chest · doi:10.1378/chest.117.4.1162 · Cited by 1,752
The Basic Science of Wound Healing
Broughton, G., Janis, J. E., & Attinger, C. E. (2006) · Plastic and Reconstructive Surgery · doi:10.1097/01.prs.0000225430.42531.c2 · Cited by 1,519
Cited by
Metal–Organic-Framework-Based Materials for Antimicrobial Applications
Li, R., Chen, T., & Pan, X. (2021) · ACS Nano · doi:10.1021/acsnano.0c09617 · Cited by 555
Photocatalytic Antimicrobials: Principles, Design Strategies, and Applications
Ran, B., Ran, L., Wang, Z., Liao, J., Li, D., Chen, K., Cai, W., Hou, J., & Peng, X. (2023) · Chemical Reviews · doi:10.1021/acs.chemrev.3c00326 · Cited by 357
Multifunctional metal–organic framework heterostructures for enhanced cancer therapy
Liu, J., Huang, J., Zhang, L., & Lei, J. (2021) · Chemical Society Reviews · doi:10.1039/d0cs00178c · Cited by 285
Metadata
- Authors
- Chen, M., Long, Z., Dong, R., Wang, L., Zhang, J., Li, S., Zhao, X., Hou, X., Shao, H., & Jiang, X.
- Venue
- Small
- Publisher
- Wiley
- Published
- 2020-01-22
- Volume
- 16
- Issue
- 7
- Pages
- e1906240-e1906240
- ISSN
- 1613-6810 (ISSN-L)
- 1613-6829
- OpenAlex
- W3002432126
- Cited by
- 225
- References
- 2
- FWCI
- 18.39
- Type
- journal article
- Language
- en
- Open access
- closed
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- Chen, M., Long, Z., Dong, R., Wang, L., Zhang, J., Li, S., Zhao, X., Hou, X., Shao, H., & Jiang, X. (2020). Titanium Incorporation into Zr‐Porphyrinic Metal–Organic Frameworks with Enhanced Antibacterial Activity against Multidrug‐Resistant Pathogens. Small. https://doi.org/10.1002/smll.201906240
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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