Multifunctional metal–organic framework heterostructures for enhanced cancer therapy
Abstract
We review the general principle of the design and functional modulation of nanoscaled MOF heterostructures, and biomedical applications in enhanced therapy.
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Combining MOFs with functional materials provides a novel approach to creating multifunctional hybrids for cancer therapies like PDT, PTT, immunotherapy, chemotherapy, and combination therapy.
“As a result, combining MOFs with functional materials provides a novel approach to creating multifunctional hybrids for cancer therapies like PDT, PTT, immunotherapy, chemotherapy, and combination therapy, among others.125”
From Smart nanoparticles for cancer therapy (2023) · cites this paper as [125]
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References 305 · Cited by 285
- Authors
- Liu, J., Huang, J., Zhang, L., & Lei, J.
- Affiliations
- Nanjing Agricultural University (CN)
- State Key Laboratory of Analytical Chemistry for Life Science (CN)
- Corresponding author
- Lei, Jianping
- Venue
- Chemical Society Reviews
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2021
- Volume
- 50
- Issue
- 2
- Pages
- 1188-1218
- ISSN
- 0306-0012 (ISSN-L)
- 1460-4744
- OpenAlex
- W3111222019
- Cited by
- 285
- References
- 305
- Citations by year
- 2026: 39 · 2025: 53 · 2024: 53 · 2023: 58 · 2022: 51 · 2021: 30 · 2020: 1
- FWCI
- 1.57
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Chemical Society Reviews (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Natural Science Foundation of China (21675084, 21890741)
- Topics
- Physical Sciences › Chemistry › Inorganic Chemistry › Metal-Organic Frameworks: Synthesis and Applications
- Physical Sciences › Engineering › Biomedical Engineering › Nanoplatforms for cancer theranostics
- Physical Sciences › Chemistry › Organic Chemistry › Supramolecular Chemistry and Complexes
- Keywords
- metal-organic frameworks, multifunctional nanomaterials, cancer therapy, photodynamic therapy, photothermal therapy, chemotherapy, radiotherapy, immunotherapy, theranostics, nanoparticle encapsulation, biomolecule encapsulation, ligand design, in situ nanoparticle growth, post-modification, intracellular microenvironment
- MeSH terms
- Metal-Organic Frameworks, Animals, Antineoplastic Agents, HeLa Cells, Humans, Neoplasms, Neoplasms, Experimental, Photochemotherapy, Mice, Nanoparticles
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