C957T polymorphism of dopamine D2 receptor gene affects striatal DRD2 in vivo availability by changing the receptor affinity

Hirvonen, Mika M., Laakso, Aki, Någren, Kjell, Rinne, Juha O., Pohjalainen, Tiina, Hietala, Jarmo·2009·Synapse
DOI 10.1002/syn.20672

Cited by (176)

Items 101–176 of 176

  1. Association between DRD2/ANKK1 TaqIA Polymorphism and Susceptibility with Tourette Syndrome: A Meta-Analysis
    Aihua Yuan, Liang Su, Shunying Yu, Chunbo Li, Tao Yu, Jinhua Sun · 2015 · PLoS ONE
  2. Association between Dopamine Receptor D2 (DRD2) Variations rs6277 and rs1800497 and Cognitive Performance According to Risk Type for Psychosis: A Nested Case Control Study in a Finnish Population Sample
    Hugh Ramsay, Jennifer H. Barnett, Jouko Miettunen, Sari Mukkala, Pirjo H. Mäki, Johanna Liuhanen, Graham K. Murray, Marjo‐Riitta Järvelin, Hanna Maria Ollila, Tiina Paunio et al. · 2015 · PLoS ONE
  3. PharmGKB summary
    Huaiyu Mi, Paul D. Thomas, Huijun Z. Ring, Ruhong Jiang, Katrin Sangkuhl, Teri E. Klein, Russ Biagio Altman · 2010 · Pharmacogenetics and Genomics
  4. Dopamine multilocus genetic profiles predict sex differences in reactivity of the human reward system
    Esther Kristina Diekhof, Anja Richter, Katja Brodmann, Oliver Gruber · 2021 · Brain Structure and Function
  5. The DRD2 C957T polymorphism and the Attentional Blink—A genetic association study
    Andrea Felten, Christian Montag, Cornelia Kranczioch, Sebastian A. Markett, Nora T. Walter, Martin Reuter · 2012 · European Neuropsychopharmacology
  6. Genetic Variations in COMT and DRD2 Modulate Attentional Bias for Affective Facial Expressions
    Pingyuan Gong, Guomin Shen, She Li, Guoping Zhang, Hongchao Fang, Lei Lin, Peizhe Zhang, Fuchang Zhang · 2013 · PLoS ONE
  7. Clinical and Genetic Factors Associated With the Breast Cancer-Related Sleep Disorders: The “CAGE-Sleep” Study–A Cross-Sectional Study
    Aline Hajj, Roula El Hachem, Rita Khoury, Tamara Nehme, Souheil R. Hallit, Fady L. Nasr, Fady El Karak, Georges Y. Chahine, Joseph Gergi Kattan, Lydia Rabbaa Khabbaz · 2021 · Journal of Pain and Symptom Management
  8. Association Between DRD2 and DRD4 Polymorphisms and Eating Disorders in an Italian Population
    Maria Rachele Ceccarini, Simona Fittipaldi, Cinzia Ciccacci, Erika Granese, Federica Centofanti, Laura Dalla Ragione, Matteo Bertelli, Tommaso Beccari, Annalisa Botta · 2022 · Frontiers in Nutrition
  9. Dopamine D2 receptor gene polymorphisms and externalizing behaviors in children and adolescents
    Osmar Henrique Della Torre, Lúcia Arisaka Paes, Taciane Barbosa Henriques, Maricilda Palandi de Mello, Eloísa Helena Rubello Valler Celeri, Paulo Dalgalarrondo, Gil Guerra‐Júnior, Amilton dos Santos Júnior · 2018 · BMC Medical Genetics
  10. Association between DRD2/ANKK1 TaqIA Allele Status and Striatal Dopamine D2/3 Receptor Availability in Alcohol Use Disorder
    Gianna Spitta, Lena Fliedner, Tobias Gleich, Tristan Zindler, Miriam Sebold, Ralph Buchert, Andreas Heinz, Jürgen Gallinat, Eva Friedel · 2022 · Journal of Integrative Neuroscience
  11. Dopamine Receptor Genes Modulate Associative Memory in Old Age
    Goran Papenberg, Nina Becker, Beata Ferencz, Moshe Naveh‐Benjamin, Erika J. Laukka, Lars Bäckman, Yvonne Brehmer · 2016 · Journal of Cognitive Neuroscience
  12. An Association Study on the Polymorphisms of Dopaminergic Genes with Working Memory in a Healthy Chinese Han Population
    Pingyuan Gong, Hang Zhang, W. Chi, Wanhua Ge, Kejin Zhang, Anyun Zheng, Xiaocai Gao, Fuchang Zhang · 2012 · Cellular and Molecular Neurobiology
  13. Motivational learning biases are differentially modulated by genetic determinants of striatal and prefrontal dopamine function
    Anni Richter, Lieke de Boer, Marc Guitart‐Masip, Gusalija Behnisch, Constanze I. Seidenbecher, Björn Hendrik Schott · 2021 · Journal of Neural Transmission
  14. Relationship between serum homovanillic acid, DRD2 C957T (rs6277), and hDAT A559V (rs28364997) polymorphisms and developmental stuttering
    Hiwa Mohammadi, Mohammad Taghi Joghataei, Zohreh Rahimi, Faezeh Faghihi, Hashem Farhangdoost · 2018 · Journal of Communication Disorders
  15. The COMT Val158Met polymorphism does not modulate the after‐effect of tDCS on working memory
    Bryant J. Jongkees, Alexandra A. Loseva, Fatemeh Yavari, Michael Andreas Nitsche, Lorenza S. Colzato · 2018 · European Journal of Neuroscience
  16. People are different: tyrosine's modulating effect on cognitive control in healthy humans may depend on individual differences related to dopamine function
    Bryant J. Jongkees, Bernhard Hommel, Lorenza S. Colzato · 2014 · Frontiers in Psychology
  17. Linkage and association of variants in the dopamine receptor 2 gene (DRD2) with polycystic ovary syndrome
    Mutaz Amin, Nicholas Horst, Claudia Gragnoli · 2023 · Journal of Ovarian Research
  18. Association of expression of DRD2 rs1800497 polymorphism with migraine risk in Han Chinese individuals
    Yingfeng Deng, Jianping Huang, Huijun Zhang, Xueqin Zhu, Qin Gong · 2018 · Journal of Pain Research
  19. Schizophrenia‐associated gene dysbindin‐1 and tardive dyskinesia
    Miriam S. Maes, Justin Lu, Arun Kumar Tiwari, Natalie Freeman, Vincenzo De Luca, Daniel J. Müller, Aristotle N. Voineskos, Steven G. Potkin, Jeffrey Alan Lieberman, Herbert Y. Meltzer et al. · 2020 · Drug Development Research
  20. The C957T polymorphism in the dopamine receptor D2 gene modulates domain-general category learning
    Zilong Xie, W. Todd Maddox, John E. McGeary, Bharath Chandrasekaran · 2015 · Journal of Neurophysiology
  21. Interaction Effects of DRD2 Genetic Polymorphism and Interpersonal Stress on Problematic Gaming in College Students
    Esther Kim, Dojin Lee, KyuMi Do, Jueun Kim · 2022 · Genes
  22. The Dopamine Receptor D2 C957T Polymorphism Modulates Early Components of Event-Related Potentials in Visual Word Recognition Task
    Вера Евгеньевна Голимбет, Гарах Жанна Валерьевна, Yuliya Zaytseva, М. В. Алфимова, Tatyana Lezheiko, Nikolay V. Kondratyev, Alexander B. Shmukler, I. Gurovich, В. Б. Стрелец · 2017 · Neuropsychobiology
  23. Genetic contributions to brain serotonin transporter levels in healthy adults
    S.E.P. Bruzzone, Arafat Nasser, Sanjay S. Aripaka, Marie Spies, Brice Ozenne, Peter Steen Jensen, Gitte M. Knudsen, Vibe G. Frøkjær, Patrick M. Fisher · 2023 · Scientific Reports
  24. Regulatory rare variants of the dopaminergic gene ANKK1 as potential risk factors for Parkinson’s disease
    Estela Pérez-Santamarina, P. García-Ruiz, D. Martínez-Rubio, M. Ezquerra, Irene Pla-Navarro, J. Puente, M. Marti, F. Palau, J. Hoenicka · 2021 · Scientific Reports
  25. Dopamine multilocus genetic profile influence on reward network in chronic insomnia disorder with depression
    Liang Gong, Kang Chen, Hongyu Zhang, Shang Zhang, Ronghua Xu, Duan Liu, Bei Zhang, Siyi Yu, Chunhua Xi · 2023 · Sleep Medicine
  26. Advancing Psychiatric Pharmacogenomics Using Drug Development Paradigms
    Ryan M. Smith · 2017 · Pharmacogenomics
  27. The Influence of Hippocampal Dopamine D2 Receptors on Episodic Memory Is Modulated byBDNFandKIBRAPolymorphisms
    Goran Papenberg, Nina Karalija, Alireza Salami, Micael Andersson, Jan Axelsson, Katrine Riklund, Ulman Lindenberger, Lars H Nyberg, Lars Bäckman · 2019 · Journal of Cognitive Neuroscience
  28. The influence of dopaminergic polymorphisms on selective stopping
    Irene Rincón‐Pérez, Víctor Echeverry‐Alzate, Alberto J. Sánchez‐Carmona, Kora‐Mareen Bühler, José Antonio Hinojosa, Jose Antonio López‐Moreno, Jacobo Albert · 2019 · Behavioural Brain Research
  29. Effects of OPRM1 and DRD2 on brain structure in drug-naïve adolescents: Genetic and neural vulnerabilities to substance use
    Giorgia Picci, Diana H. Fishbein, John W. VanMeter, Emma J. Rose · 2021 · Psychopharmacology
  30. A common polymorphism in the dopamine transporter gene predicts working memory performance and in vivo dopamine integrity in aging
    Nina Karalija, Ylva Köhncke, Sandra Düzel, Lars Bertram, Goran Papenberg, Ilja Demuth, Christina M. Lill, Jarkko J. Johansson, Katrine Riklund, Martin Lövdén et al. · 2021 · NeuroImage
  31. ANKK1 and TH gene variants in combination with paternal maltreatment increase susceptibility to both cognitive and attentive impulsivity
    Sara Palumbo, Veronica Mariotti, Stefano Vellucci, Klizia Antonelli, Nathaniel E. Anderson, Carla L. Harenski, Pietro Pietrini, Kent A. Kiehl, Silvia Pellegrini · 2022 · Frontiers in Psychiatry
  32. A systems omics-based approach to decode substance use disorders and neuroadaptations
    Avinash M. Veerappa, Gurudutt Pendyala, Chittibabu Guda · 2021 · Neuroscience & Biobehavioral Reviews
  33. Risk Factors for Levodopa-Induced Dyskinesia
    Jee‐Young Lee, Beom S. Jeon · 2014 · Springer eBooks
  34. Association of ANKK1 and DRD2 gene polymorphisms with exercise addiction among elite athletes
    Yeliz Ay Yıldız, Anıl Kasakolu, Celal Bulğay, Türker Bıyıklı, Hasan Hüseyin Kazan, Seyrani Koncagül, Işık Bayraktar, Ildus I. Ahmetov, Mark Damian Griffiths, Mehmet Ali Ergün et al. · 2025 · International Journal of Sport and Exercise Psychology
  35. Fronto-striatal dopamine D2 receptor availability is associated with cognitive variability in older individuals with low dopamine integrity
    Saana M. Korkki, Goran Papenberg, Nina Karalija, Douglas D. Garrett, Katrine Riklund, Martin Lövdén, Ulman Lindenberger, Lars H Nyberg, Lars Bäckman · 2021 · Scientific Reports
  36. Cumulative Genetic Score of DRD2 Polymorphisms Is Associated with Impulsivity and Masked Semantic Priming
    Simon Sanwald, Christian Montag, Markus Kiefer · 2022 · Journal of Molecular Neuroscience
  37. An Examination of Mechanisms by which Synonymous Mutations may Alter Protein Levels, Structure and Functions
    Yiming J. Zhang, Zsuzsa Bebők · 2022 · Springer eBooks
  38. The association between perinatal hypoxia exposure and externalizing symptoms and children’s decision making in conditions of uncertainty is moderated by DRD2 genotype
    Roisin White, Lisa M. Gatzke‐Kopp, Patrick Joseph Ryan, David M. Lydon‐Staley · 2018 · Developmental Psychobiology
  39. Functional single nucleotide polymorphisms in dopaminergic receptors D2 predict clinical response to Cariprazine
    Marco De Pieri, Marco Ferrari, Franca Marino, Rafael Traber, Emilio Bolla, Marco Cosentino · 2023 · Frontiers in Pharmacology
  40. The genetics of self-reported trait impulsivity: Contribution of catecholaminergic gene variants in European ancestry individuals
    Kora‐Mareen Bühler, Irene Rincón‐Pérez, Javier Calleja‐Conde, Jacobo Albert, José Antonio Hinojosa, Elena Giné, Víctor Echeverry‐Alzate, José Antonio López‐Moreno, Evelio Huertas · 2022 · Personality and Individual Differences
  41. The interplay of dopaminergic genotype and parent–child relationship in relation to intra‐individual response time variability in preschoolers: A replication study
    Yuewen Zhang, Zhenhong Wang · 2024 · Developmental Science
  42. Lifespan Changes in the Countermanding Performance of Young and Middle Aged Adult Rats
    Jonathan Beuk, Richard J Beninger, Martin Paré · 2016 · Frontiers in Aging Neuroscience
  43. The ANKK 1/ DRD 2 locus is a genomic substrate for affective priming and recognition of angry faces
    Alejandra Koeneke, Guillermo Ponce, Janet Hoenicka, Evelio Huertas · 2015 · Brain and Behavior
  44. Lifespan longitudinal changes in mesocortical thickness and executive function: Role of dopaminergic genetic predisposition
    Giuseppe G. Miranda, Chen Gonen, Jessica N. Kraft, Karen M. Rodrigue, Kristen M. Kennedy · 2024 · Neurobiology of Aging
  45. Disordered eating in early childhood: DRD2 and COMT gene polymorphisms and behavioral features in family trios
    Esterina Pascale, Silvia Cimino, Luca Cerniglia, Cristiano Giuliani, Arturo Bevilacqua · 2026 · Eating and Weight Disorders - Studies on Anorexia Bulimia and Obesity
  46. Increased dopamine availability magnifies nicotine effects on cognitive control: A pilot study
    Stefan Ahrens, Joana Laux, Christina Müller, Christiane M. Thiel · 2020 · Journal of Psychopharmacology
  47. Hippocampal and motor regions contribute to memory benefits after enacted encoding: cross-sectional and longitudinal evidence
    Maryam Noroozıan, Reza Kormi‐Nouri, Lars H Nyberg, Jonas Persson · 2022 · Cerebral Cortex
  48. Gene Variants Involved in the Etiopathogenesis of Eating Disorders: Neuropeptides, Neurotransmitters, Hormones, and Their Receptors
    Maria Rachele Ceccarini, Matteo Bertelli, Elisabetta Albi, Laura Dalla Ragione, Tommaso Beccari · 2022 · Springer eBooks
  49. Genetic diversity of the North African population revealed by the typing of SNPs in the DRD2/ANKK1 genomic region
    Souhir Mestiri, Sami Boussetta, ANDREW J. PAKSTIS, Sarra Elkamel, Amel Ben Ammar Elgaaïed, Kenneth K. Kídd, Lotfi Cherni · 2021 · Gene
  50. Genetic Modifiers of Caffeine Consumption and Risk of Myocardial Infarction
    Laura Anne Da Costa · 2011 · TSpace (University of Toronto)
  51. Efficacy of Inhibitory Control in Antisaccade Task and the Polymorphisms of DRD2 Dopamine Receptor Gene in Schizophrenic Patients
    Zinaida I. Storozheva, Vadim M. Brodyansky, Anna V. Kirenskaya, Андрей Анатольевич Ткаченко, Alexander O. Kibitov · 2018 · Human Physiology
  52. Gene Variants Involved in the Etiopathogenesis of Eating Disorders: Neuropeptides, Neurotransmitters, Hormones, and Their Receptors
    Maria Rachele Ceccarini, Matteo Bertelli, Elisabetta Albi, Laura Dalla Ragione, Tommaso Beccari · 2023 · Springer eBooks
  53. D2 dopamine receptor expression, reactivity to rewards, and reinforcement learning in a complex value-based decision-making task
    Cristina Bañuelos, Kasey G. Creswell, Catherine P. Walsh, Stephen B. Manuck, Peter J. Gianaros, Timothy Verstynen · 2024 · Social Cognitive and Affective Neuroscience
  54. A comparative analysis of manual point-counting method and automated pixel-counting method of area percentage estimation on placenta.
    Ruchika Gupta, Sompal Singh · 2009 · PubMed
  55. Genetic variation in the dopamine system is associated with mixed‐strategy decision‐making in patients with Parkinson's disease
    Ashley C. Parr, Heidi C. Riek, Brian C. Coe, Giovanna Pari, Mario Masellis, Connie Marras, Douglas P. Munoz · 2022 · European Journal of Neuroscience
  56. The influence of hippocampal dopamine D2 receptor losses on episodic-memory decline across 5 years is moderated by BDNF and KIBRA polymorphisms
    Goran Papenberg, Nina Karalija, Jarkko J. Johansson, Micael Andersson, Jan Axelsson, Katrine Riklund, Ulman Lindenberger, Lars H Nyberg, Lars Bäckman · 2024 · Cortex
  57. D2 dopamine receptor expression, sensitivity to rewards, and reinforcement learning in a complex value-based decision-making task
    Cristina Bañuelos, Kasey G. Creswell, Catherine P. Walsh, Stephen B. Manuck, Peter J. Gianaros, Timothy Verstynen · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  58. GENETIC LINKS TO THE REINFORCING EFFECTS OF ALCOHOL IN A SOCIAL CONTEXT
    Kasey G. Creswell · 2012 · D-Scholarship@Pitt (University of Pittsburgh)
  59. The Impact of Genetic Polymorphisms on Neuroreceptor Imaging
    Matthäus Willeit, Siegfried F. Kasper, Nicole Praschak-Rieder · 2014 · Springer eBooks
  60. The Influence of Gene Environment Interaction on the Risk of Cognitive Impairment: Reducing Sexual Risk Behaviors and Alcohol Use in HIV-infected Adults
    Karina Villalba · 2014
  61. Behavioral impulsivity and hallucinations : insights from Parkinson's disease
    Paymon Ashourian · 2011 · DSpace@MIT (Massachusetts Institute of Technology)
  62. A Behavioural Genetic Model of the Mechanisms Underlying the Link Between Obesity and Dimensional Measures of Attention-Deficit/Hyperactivity Disorder (ADHD)
    Karen Allison Patte · 2015 · YorkSpace (York University)
  63. Genetic Determinants of Carbohydrate Consumption
    Karen M. Eny · 2010 · TSpace (University of Toronto)
  64. Polimorfismos dos genes dos receptores de dopamina D2 e de somatostatina subtipos 2 e 5 e resposta ao tratamento medicamentoso de pacientes portadores de adenomas hipofisários
    Cristina Bellotti Formiga Bueno · 2017
  65. The Impact of Genetic Polymorphisms on Neuroreceptor Binding: Results from PET and SPECT Neuroreceptor Imaging Studies
    Irene Graf, Matthäus Willeit, Siegfried F. Kasper, Nicole Praschak-Rieder · 2020 · Springer eBooks
  66. The relation among aging, dopamine-regulating genes, and neurocognition
    Xin Li · 2020 · Figshare
  67. Dopamina e comportamento alimentar: polimorfismos em receptores dopaminérgicos e fenótipos relacionados à obesidade
    Gabriela Kaufmann, Fabiane Dresch, Stephanie Cristine Hepp Rehfeldt, Júlia Pasqualini Genro, Verônica Contini · 2021 · Clinical & Biomedical Research
  68. Faculty Opinions recommendation of Neuroimaging in psychiatric pharmacogenetics research: the promise and pitfalls.
    James Steven Leeder, Andrea Gaedigk · 2013 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  69. Cognitive, Experiential and Genetic Contribution to Depressive Symptoms in Male and Female Students with a History of Concussion
    Kaylyn Dixon · 2016
  70. Associação entre polimorfismos do gene do receptor D2 de dopamina e sintomas psicopatológicos em crianças e adolescentes
    Osmar Henrique Della Torre · 2016
  71. Avaliação de marcadores genéticos em uma coorte de indivíduos em alto risco para psicose Subclinical Symptoms Assessment and Prodromal Psychosis Program (SSAPP)
    Júlia Hatagami Marques · 2023
  72. Additional file 1 of Linkage and association of variants in the dopamine receptor 2 gene (DRD2) with polycystic ovary syndrome
    Mutaz Amin, Nicholas Horst, Claudia Gragnoli · 2023 · Figshare
  73. Genetic addiction risk analysis for “preaddiction” severity index (PAI): A neurobiological behavioral octopus
    Kenneth Blum, David C. Han, Abdalla Bowirrat, Bernard William Downs, Debasis Bagchi, Panayotis K. Thanos, David A. Baron, Eric R. Braverman, Catherine A. Dennen, John Giordano et al. · 2024 · Elsevier eBooks
  74. Neurogenetics of Human Decision-Making
    Svea Annika Hogeterp, Annabel Vetterlein, Martin Reuter · 2025 · Studies in neuroscience, psychology and behavioral economics
  75. Additional file 2 of Linkage and association of variants in the dopamine receptor 2 gene (DRD2) with polycystic ovary syndrome
    Mutaz Amin, Nicholas Horst, Claudia Gragnoli · 2023 · Figshare
  76. A Four-Dimensional Model of Attention-Deficit/Hyperactivity Disorder: Toward Improved Recognition of Female ADHD
    Jarosław Jóźwiak · 2026 · International Journal of Molecular Sciences