Ductus venosus Doppler in screening for trisomies 21, 18 and 13 and Turner syndrome at 11–13 weeks of gestation

UK multicentre project on assessment of risk of trisomy 21 by maternal age and fetal nuchal-translucency thickness at 10–14 weeks of gestation

Snijders, R., Noble, P., Sebire, N., Souka, A., & Nicolaides, K. (1998) · The Lancet · doi:10.1016/s0140-6736(97)11280-6 · Cited by 1,572 · see citing works

Multicenter study of first‐trimester screening for trisomy 21 in 75 821 pregnancies: results and estimation of the potential impact of individual risk‐orientated two‐stage first‐trimester screening

Nicolaides, K. H., Spencer, K., Avgidou, K., Faiola, S., & Falcón, O. (2005) · Ultrasound in Obstetrics and Gynecology · doi:10.1002/uog.1860 · Cited by 450 · see citing works

Screening for chromosomal abnormalities at 10–14 weeks: the role of ductus venosus blood flow

Matias, A., Gomes, C. C., Flack, N. J., Montenegro, N. A. M. D. M., & Nicolaides, K. H. (1998) · Ultrasound in Obstetrics and Gynecology · doi:10.1046/j.1469-0705.1998.12060380.x · Cited by 316 · see citing works

Screening for trisomies 21, 18 and 13 by maternal age, fetal nuchal translucency, fetal heart rate, free -hCG and pregnancy-associated plasma protein-A

Kagan, K. O., Wright, D., Valencia, C. M. M., Maíz, N., & Nicolaides, K. H. (2008) · Human Reproduction · doi:10.1093/humrep/den224 · Cited by 263 · see citing works

First‐trimester maternal serum pregnancy‐associated plasma protein‐A and pre‐eclampsia

Poon, L. C., Maíz, N., Valencia, C. M. M., Plasencia, W., & Nicolaides, K. H. (2008) · Ultrasound in Obstetrics and Gynecology · doi:10.1002/uog.6280 · Cited by 237 · see citing works

Cardiac defects in chromosomally normal fetuses with abnormal ductus venosus blood flow at 10–14 weeks

Matias, A., Huggon, I. C., Areias, J. C., Montenegro, N. A. M. D. M., & Nicolaides, K. H. (1999) · Ultrasound in Obstetrics and Gynecology · doi:10.1046/j.1469-0705.1999.14050307.x · Cited by 213 · see citing works

First‐trimester biochemical markers of aneuploidy and the prediction of small‐for‐gestational age fetuses

Spencer, K., Cowans, N. J., Avgidou, K., Molina, F. S., & Nicolaides, K. H. (2007) · Ultrasound in Obstetrics and Gynecology · doi:10.1002/uog.5165 · Cited by 155 · see citing works

Nasal bone in first-trimester screening for trisomy 21

Cicero, S., Avgidou, K., Rembouskos, G., Kagan, K. O., & Nicolaides, K. H. (2006) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2005.12.057 · Cited by 128 · see citing works

The role of ductus venosus blood flow assessment in screening for chromosomal abnormalities at 10–16 weeks of gestation

Antolin, E., Comas, C., Torrents, M., Muñoz, A., Figueras, F., Echevarría, M., Cararach, M., & Carrera, J. M. (2001) · Ultrasound in Obstetrics and Gynecology · doi:10.1046/j.1469-0705.2001.00395.x · Cited by 107 · see citing works

Learning curve for Doppler assessment of ductus venosus flow at 11 + 0 to 13 + 6 weeks' gestation

Maíz, N., Kagan, K. O., Milovanović, Z., Çelik, E., & Nicolaides, K. H. (2008) · Ultrasound in Obstetrics and Gynecology · doi:10.1002/uog.5282 · Cited by 93 · see citing works

Birth statistics : Review of the Registrar General on births and patterns of family building in England and Wales

Surveys (1978) · HMSO eBooks · Cited by 92 · see citing works

Age-related changes in myocardial relaxation and sarcoplasmic reticulum function

Kaufman, T. M., Horton, J. W., White, D. J., & Mahony, L. (1990) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.1990.259.2.h309 · Cited by 83 · see citing works

Application of Ductus venosus Doppler Velocimetry for the Detection of Fetal Aneuploidy in the First Trimester of Pregnancy

Murta, C. G. V., Moron, A. F., de Ávila, M. A. P., & Weiner, C. P. (2002) · Fetal Diagnosis and Therapy · doi:10.1159/000063185 · Cited by 82 · see citing works

First-Trimester Ductus venosus Velocimetry in Relation to Nuchal Translucency Thickness and Fetal Karyotype

Zoppi, M. A., Putzolu, M., Ibba, R. M., Floris, M., & Monni, G. (2002) · Fetal Diagnosis and Therapy · doi:10.1159/000048007 · Cited by 82 · see citing works

Ductus venosus assessment at the time of nuchal translucency measurement in the detection of fetal aneuploidy

BORRELL, A., Martínez, J. M., Serés, A., Borobio, V., Cararach, V., & Fortuny, A. (2003) · Prenatal Diagnosis · doi:10.1002/pd.716 · Cited by 80 · see citing works

Screening for trisomy 21 by fetal tricuspid regurgitation, nuchal translucency and maternal serum free β-hCG and PAPP-A at 11 + 0 to 13 + 6 weeks

Falcon, O., Auer, M., Gerovassili, A., Spencer, K., & Nicolaides, K. H. (2005) · Ultrasound in Obstetrics and Gynecology · doi:10.1002/uog.2699 · Cited by 75 · see citing works

Ductus venosus blood flow assessment at 11 to 14 weeks of gestation and fetal outcome

Toyama, J., Brizot, M. D. L., Liao, A. W., Lopes, L. M., Nomura, R. M. Y., Saldanha, F. A. T., & Zugaib, M. (2004) · Ultrasound in Obstetrics and Gynecology · doi:10.1002/uog.1025 · Cited by 70 · see citing works

Screening for Adverse Pregnancy Outcome by Ductus Venosus Doppler at 11–13+6 Weeks of Gestation

Maíz, N., Valencia, C. M. M., Emmanuel, E. E., STABOULIDOU, I., & Nicolaides, K. H. (2008) · Obstetrics and Gynecology · doi:10.1097/aog.0b013e3181834608 · Cited by 69 · see citing works

Post‐natal developmental changes in the length‐tension relationship of cat papillary muscles.

Davies, P., Dewar, J., Tynan, M. J., & Ward, R. (1975) · The Journal of Physiology · doi:10.1113/jphysiol.1975.sp011181 · Cited by 69 · see citing works

Fetal Atrioventricular Flow-Velocity Waveforms and Their Relation to Arterial and Venous Flow-Velocity Waveforms at 8 to 20 Weeks of Gestation

van Splunder, P., Stijnen, T., & Wladimiroff, J. W. (1996) · Circulation · doi:10.1161/01.cir.94.6.1372 · Cited by 66 · see citing works

The publishing of papers on first‐trimester Doppler

Campbell, S. C., & Platt, L. D. (1999) · Ultrasound in Obstetrics and Gynecology · doi:10.1046/j.1469-0705.1999.14030159.x · Cited by 54 · see citing works

First-Trimester Ductus Venosus, Nasal Bones, and Down Syndrome in a High-Risk Population

Prefumo, F., Sethna, F., Sairam, S., Bhide, A., & Thilaganathan, B. (2005) · Obstetrics and Gynecology · doi:10.1097/01.aog.0000161368.77506.ab · Cited by 49 · see citing works

Screening for fetal aneuploidies at 11 to 13 weeks

Nicolaides, K. H. (2011) · Prenatal Diagnosis · doi:10.1002/pd.2637 · Cited by 641 · see citing works

<scp>ISUOG</scp> Practice Guidelines: performance of first‐trimester fetal ultrasound scan

(2013) · Ultrasound in Obstetrics &amp; Gynecology · doi:10.1002/uog.12342 · Cited by 621 · see citing works

Turning the Pyramid of Prenatal Care

Nicolaides, K. H. (2011) · Fetal Diagnosis and Therapy · doi:10.1159/000324320 · Cited by 357 · see citing works

ISUOG Practice Guidelines (updated): performance of 11–14‐week ultrasound scan

International Society of Ultrasound in Obstetrics and Gynecology, Bilardo, C. M., Chaoui, R., Hyett, J. A., Kagan, K. O., Karim, J. N., Papageorghiou, A. T., Poon, L. C., Salomon, L. J., Syngelaki, A., et al. (2023) · Ultrasound in Obstetrics and Gynecology · doi:10.1002/uog.26106 · Cited by 283 · see citing works

Systematic review of first-trimester ultrasound screening for detection of fetal structural anomalies and factors that affect screening performance

Karim, J. N., Roberts, N. W., Salomon, L. J., & Papageorghiou, A. T. (2017) · Ultrasound in Obstetrics &amp; Gynecology · doi:10.1002/uog.17246 · Cited by 266 · see citing works

Clinical practice guidelines for the care of girls and women with Turner syndrome.

Gravholt, C. H., Andersen, N. H., Christin-Maitre, S., Davis, S. M., Duijnhouwer, A., Gawlik, A., Maciel-Guerra, A. T., Gutmark-Little, I., Fleischer, K., Hong, D., et al. (2024) · European Journal of Endocrinology · doi:10.1093/ejendo/lvae050 · Cited by 224 · see citing works

Contribution of Fetal Tricuspid Regurgitation in First-Trimester Screening for Major Cardiac Defects

Pereira, S., Ganapathy, R., Syngelaki, A., Maíz, N., & Nicolaides, K. H. (2011) · Obstetrics and Gynecology · doi:10.1097/aog.0b013e31821aa720 · Cited by 115 · see citing works

Diagnosis of major heart defects by routine first‐trimester ultrasound examination: association with increased nuchal translucency, tricuspid regurgitation and abnormal flow in ductus venosus

Minnella, G., Crupano, F. M., Syngelaki, A., Zidere, V., Akolekar, R., & Nicolaides, K. H. (2019) · Ultrasound in Obstetrics and Gynecology · doi:10.1002/uog.21956 · Cited by 112 · see citing works

Prediction of miscarriage and stillbirth at 11–13 weeks and the contribution of chorionic villus sampling

Akolekar, R., Bower, S. J., Flack, N. J., Bilardo, C. M., & Nicolaides, K. H. (2011) · Prenatal Diagnosis · doi:10.1002/pd.2644 · Cited by 95 · see citing works

Non-Invasive Prenatal Testing: Current Perspectives and Future Challenges

Carbone, L., Cariati, F., Sarno, L., Conforti, A., Bagnulo, F., Strina, I., Pastore, L., Maruotti, G. M., & Alviggi, C. (2020) · Genes · doi:10.3390/genes12010015 · Cited by 94 · see citing works

First trimester ultrasound tests alone or in combination with first trimester serum tests for Down's syndrome screening

Alldred, S. K., Takwoingi, Y., Guo, B., Pennant, M. E., Deeks, J. J., Neilson, J. P., & Alfirević, Ž. (2017) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd012600 · Cited by 91 · see citing works

Ductus Venosus in the First Trimester: Contribution to Screening of Chromosomal, Cardiac Defects and Monochorionic Twin Complications

Maíz, N., & Nicolaides, K. H. (2010) · Fetal Diagnosis and Therapy · doi:10.1159/000314036 · Cited by 81 · see citing works

Ultrasound screening: Status of markers and efficacy of screening for structural abnormalities

Rao, R., & Platt, L. D. (2016) · Seminars in Perinatology · doi:10.1053/j.semperi.2015.11.009 · Cited by 78 · see citing works

First-trimester screening for trisomies 18 and 13, triploidy and Turner syndrome by detailed early anomaly scan

Wagner, P., Sonek, J., Hoopmann, M., Abele, H., & Kagan, K. O. (2016) · Ultrasound in Obstetrics &amp; Gynecology · doi:10.1002/uog.15829 · Cited by 68 · see citing works

Two‐stage first‐trimester screening for trisomy 21 by ultrasound assessment and biochemical testing

Kagan, K. O., STABOULIDOU, I., Cruz, J. D. J., Wright, D. E., & Nicolaides, K. H. (2010) · Ultrasound in Obstetrics and Gynecology · doi:10.1002/uog.7663 · Cited by 67 · see citing works

Antenatal screening for chromosomal abnormalities

Kagan, K. O., Sonek, J., & Kozlowski, P. (2022) · Archives of Gynecology and Obstetrics · doi:10.1007/s00404-022-06477-5 · Cited by 59 · see citing works

Prevalence and Outcome of Absence of Ductus Venosus at 11+0 to 13+6 Weeks

STABOULIDOU, I., Pereira, S., Cruz, J. D. J., Syngelaki, A., & Nicolaides, K. H. (2011) · Fetal Diagnosis and Therapy · doi:10.1159/000323593 · Cited by 57 · see citing works

First‐trimester screening for chromosomal abnormalities by integrated application of nuchal translucency, nasal bone, tricuspid regurgitation and ductus venosus flow combined with maternal serum free β‐hCG and PAPP‐A: a 5‐year prospective study

Ghaffari, S. R., Tahmasebpour, A., Jamal, A., Hantoushzadeh, S., Eslamian, L., Marsoosi, V., Fattahi, F., Rajaei, M., Niroomanesh, S., Borna, S., et al. (2011) · Ultrasound in Obstetrics and Gynecology · doi:10.1002/uog.10051 · Cited by 53 · see citing works

First‐trimester contingent screening for trisomies 21, 18 and 13 by fetal nuchal translucency and ductus venosus flow and maternal blood cell‐free DNA testing

Kagan, K. O., Wright, D. E., & Nicolaides, K. H. (2014) · Ultrasound in Obstetrics and Gynecology · doi:10.1002/uog.14691 · Cited by 53 · see citing works

Safe use of Doppler ultrasound during the 11 to 13 + 6‐week scan: is it possible?

Salvesen, K. Å., Lees, C. C., Abramowicz, J. S., Brezinka, C., ter Haar, G., & Maršál, K. (2011) · Ultrasound in Obstetrics and Gynecology · doi:10.1002/uog.9025 · Cited by 52 · see citing works

First trimester ultrasound screening for Down syndrome based on maternal age, fetal nuchal translucency and different combinations of the additional markers nasal bone, tricuspid and ductus venosus flow

Abele, H., Wagner, P., Sonek, J., Hoopmann, M., Brucker, S. Y., Ülkümen, B. A., & Kagan, K. O. (2015) · Prenatal Diagnosis · doi:10.1002/pd.4664 · Cited by 48 · see citing works

Nuchal fold thickness, nasal bone absence or hypoplasia, ductus venosus reversed flow and tricuspid valve regurgitation in screening for trisomies 21, 18 and 13 in the early second trimester

Geipel, A., Willruth, A., Vieten, J., Gembruch, U., & Berg, C. (2010) · Ultrasound in Obstetrics and Gynecology · doi:10.1002/uog.7597 · Cited by 48 · see citing works

Prenatal Sonographic Features of Fetuses in Trisomy 13 Pregnancies (I)

Chen, C. (2009) · Taiwanese Journal of Obstetrics and Gynecology · doi:10.1016/s1028-4559(09)60292-8 · Cited by 43 · see citing works

A Mixture Model of Ductus Venosus Pulsatility Index in Screening for Aneuploidies at 11–13 Weeks’ Gestation

Maíz, N., Wright, D. E., Ferreira, A. F. A., Syngelaki, A., & Nicolaides, K. H. (2012) · Fetal Diagnosis and Therapy · doi:10.1159/000337322 · Cited by 39 · see citing works

Ultrasound bioeffects in rats: quantification of cellular damage in the fetal liver after pulsed Doppler imaging

Pellicer, B., Herraiz, S., Taboas, E., Felipo, V., Simón, C., & Pellicer, A. (2010) · Ultrasound in Obstetrics and Gynecology · doi:10.1002/uog.8842 · Cited by 36 · see citing works

Additional First-Trimester Ultrasound Markers

Sonek, J., & Nicolaides, K. H. (2010) · Clinics in Laboratory Medicine · doi:10.1016/j.cll.2010.04.004 · Cited by 35 · see citing works

Screening for adverse pregnancy outcome at early gestational age

Hourrier, S., Salomon, L. J., Dreux, S., & MULLER, F. M. (2010) · Clinica Chimica Acta · doi:10.1016/j.cca.2010.06.024 · Cited by 33 · see citing works

Do We Need to Restrict the Use of Doppler Ultrasound in the First Trimester of Pregnancy?

ter Haar, G., Abramowicz, J. S., Akiyama, I., Evans, D. H., Ziskin, M. C., & Maršál, K. (2013) · Ultrasound in Medicine & Biology · doi:10.1016/j.ultrasmedbio.2012.11.024 · Cited by 29 · see citing works

Hepatic artery Doppler in trisomy 21 and euploid fetuses at 11–13 weeks

Zvanca, M. E., Gielchinsky, Y., Abdeljawad, F. J., Bilardo, C. M., & Nicolaides, K. H. (2011) · Prenatal Diagnosis · doi:10.1002/pd.2664 · Cited by 29 · see citing works

Ultrasound safety in early pregnancy: reduced energy setting does not compromise obstetric Doppler measurements

Sande, R. K., Matre, K., Eide, G. E., & Kiserud, T. (2011) · Ultrasound in Obstetrics and Gynecology · doi:10.1002/uog.10148 · Cited by 27 · see citing works

Increased nuchal translucency and congenital heart disease

Mogra, R., Alabbad, N., & Hyett, J. A. (2012) · Early Human Development · doi:10.1016/j.earlhumdev.2012.02.009 · Cited by 26 · see citing works

Intelligent Noninvasive Diagnosis of Aneuploidy: Raw Values and Highly Imbalanced Dataset

Neocleous, A. C., Nicolaides, K. H., & Schizas, C. N. (2016) · IEEE Journal of Biomedical and Health Informatics · doi:10.1109/jbhi.2016.2608859 · Cited by 26 · see citing works

Improved diagnostic accuracy by using secondary ultrasound markers in the first‐trimester screening for trisomies 21, 18 and 13 and Turner syndrome

Orlić, N. K., Egic, A. S., Milovanović, Z., Marinković, M. D., Damnjanovic‐Pazin, B., Lukić, R., Joksić, I., Ćurković, A., & Miković, Ž. (2012) · Prenatal Diagnosis · doi:10.1002/pd.3873 · Cited by 25 · see citing works

Ductus venosus pulsatility index measurement reduces the false‐positive rate in first‐trimester screening

Timmerman, E., Rengerink, K. O., Pajkrt, E., Opmeer, B. C., van der Post, J., & Bilardo, C. M. (2010) · Ultrasound in Obstetrics and Gynecology · doi:10.1002/uog.7706 · Cited by 25 · see citing works

Combined First Trimester Screening and Cell-Free Fetal DNA – “Next Generation Screening”

Kagan, K. O., Eiben, B., & Kozlowski, P. (2014) · Ultraschall in der Medizin - European Journal of Ultrasound · doi:10.1055/s-0034-1366353 · Cited by 23 · see citing works

First Trimester Prediction of Adverse Pregnancy Outcomes—Identifying Pregnancies at Risk from as Early as 11–13 Weeks

Bouariu, A., Panaitescu, A. M., & Nicolaides, K. H. (2022) · Medicina · doi:10.3390/medicina58030332 · Cited by 25 · see citing works

Two‐stage approach for risk estimation of fetal trisomy 21 and other aneuploidies using computational intelligence systems

Neocleous, A. C., Syngelaki, A., Nicolaides, K. H., & Schizas, C. N. (2017) · Ultrasound in Obstetrics and Gynecology · doi:10.1002/uog.17558 · Cited by 23 · see citing works

Practice guidelines of the Polish Society of Gynecologists and Obstetricians - Ultrasound Section for ultrasound screening in uncomplicated pregnancy - 2020

Borowski, D., Pietryga, M., Basta, P., Cnota, W., Czuba, B., Dubiel, M., Fuchs, T., Huras, H. K., Iciek, R., Jaczyńska, R., et al. (2020) · Ginekologia Polska · doi:10.5603/gp.2020.0110 · Cited by 23 · see citing works

First‐trimester ductus venosus velocity ratio as a marker of major cardiac defects

Wagner, P., Eberle, K., Sonek, J., Berg, C., Gembruch, U., Hoopmann, M., Prodan, N., & Kagan, K. O. (2018) · Ultrasound in Obstetrics and Gynecology · doi:10.1002/uog.20099 · Cited by 22 · see citing works

Predictive Value of Free β-hCG Multiple of the Median for Women with Preeclampsia

Liu, H., Wang, Y., Wang, L., & Hao, M. (2015) · Gynecologic and Obstetric Investigation · doi:10.1159/000433434 · Cited by 21 · see citing works

What are the most common first-trimester ultrasound findings in cases of Turner syndrome?

Wiechec, M. T., Knafel, A., Nocuń, A., Wiercińska, E., Ludwin, A., & Ludwin, I. (2016) · The Journal of Maternal-Fetal & Neonatal Medicine · doi:10.1080/14767058.2016.1220525 · Cited by 20 · see citing works

The first trimester combined test for aneuploidies – a single center experience

Veduță, A., Vayna, A. M., Duţă, S., Panaitescu, A. M., Popescu, F. D., Bari, M. B., Peltecu, G. C., & Nedelea, F. M. (2017) · The Journal of Maternal-Fetal & Neonatal Medicine · doi:10.1080/14767058.2017.1336220 · Cited by 19 · see citing works

Extended First-Trimester Screening Using Multiple Sonographic Markers and Maternal Serum Biochemistry: A Five-Year Prospective Study

Hsiao, C.-H., Cheng, P.-J., Shaw, S. W., Hsu, J.-J., Chen, R.-C., Tseng, Y.-J., & Chu, W. (2014) · Fetal Diagnosis and Therapy · doi:10.1159/000357564 · Cited by 17 · see citing works

The Impact of Down Syndrome Screening on Taiwanese Down Syndrome Births: A Nationwide Retrospective Study and a Screening Result from a Single Medical Centre

Lin, S., Hsieh, C., Chen, Y.-L., Shaw, S. W., Lin, M., Chen, P., & Lee, C. (2013) · PLoS ONE · doi:10.1371/journal.pone.0075428 · Cited by 17 · see citing works

First trimester severe ductus venosus flow abnormalities in isolation or combination with other markers of aneuploidy and fetal anomalies

Wiechec, M. T., Nocuń, A., Matyszkiewicz, A., Wiercińska, E., & Latała, E. (2015) · Journal of Perinatal Medicine · doi:10.1515/jpm-2014-0323 · Cited by 17 · see citing works

Peak Serum Estradiol Level During Controlled Ovarian Stimulation Is not Associated with Lower Levels of Pregnancy-Associated Plasma Protein-A or Small for Gestational Age Infants: A Cohort Study

Dunne, C., Cho, K., Shan, A., Hutcheon, J. A., Durland, U., Seethram, K., & Havelock, J. C. (2017) · Journal of Obstetrics and Gynaecology Canada · doi:10.1016/j.jogc.2017.01.031 · Cited by 16 · see citing works

A Review of Ultrasound Imaging Techniques for the Detection of Down Syndrome

Arjunan, S. P., & Thomas, M. C. (2019) · IRBM · doi:10.1016/j.irbm.2019.10.004 · Cited by 16 · see citing works

Down Syndrome in India—Diagnosis, Screening, and Prenatal Diagnosis

Verma, I. C., Lall, M. B., & Puri, R. D. (2012) · Clinics in Laboratory Medicine · doi:10.1016/j.cll.2012.04.010 · Cited by 16 · see citing works

Assessment of the ductus venosus, tricuspid blood flow and the nasal bone in second‐trimester screening for trisomy 21

Stressig, R., Kozlowski, P., Froehlich, S., Siegmann, H. J., Hammer, R., Blumenstock, G., & Kagan, K. O. (2010) · Ultrasound in Obstetrics and Gynecology · doi:10.1002/uog.7749 · Cited by 15 · see citing works

First trimester contingent screening for trisomies 21,18,13: is this model cost efficient and feasible in public health system?

Colosi, E., D’Ambrosio, V., & Periti, E. (2016) · The Journal of Maternal-Fetal & Neonatal Medicine · doi:10.1080/14767058.2016.1268593 · Cited by 15 · see citing works

Umbilical vein blood flow at 11 + 0 to 13 + 6 weeks of gestation

Rizzo, G., Capponi, A., Pietrolucci, M. E., & Arduini, D. (2010) · The Journal of Maternal-Fetal & Neonatal Medicine · doi:10.3109/14767050903121464 · Cited by 15 · see citing works

Assessment of Foetal DNA in Maternal Blood – A Useful Tool in the Hands of Prenatal Specialists

Kagan, K. O., Hoopmann, M., & Kozlowski, P. (2012) · Geburtshilfe und Frauenheilkunde · doi:10.1055/s-0032-1327960 · Cited by 14 · see citing works

False-Positive Rate in First-Trimester Screening Based on Ultrasound and Cell-Free DNA versus First-Trimester Combined Screening with Additional Ultrasound Markers

Kagan, K. O., Maier, V., Sonek, J., Abele, H., Lüthgens, K., Schmid, M., Wagner, P., & Hoopmann, M. (2018) · Fetal Diagnosis and Therapy · doi:10.1159/000489121 · Cited by 14 · see citing works

Universal Cell Free DNA or Contingent Screening for Trisomy 21: Does It Make a Difference? A Comparative Study with Real Data

Prodan, N. C., Wiechers, C., Geipel, A., Walter, A., Siegmann, H. J., Kozlowski, P., Hoopmann, M., & Kagan, K. O. (2022) · Fetal Diagnosis and Therapy · doi:10.1159/000523738 · Cited by 14 · see citing works

First trimester contingent test as a screening method for Down’s syndrome. A prospective study in the general population

Sainz‐Bueno, J. A., Serrano, R., Borrero, C., & Turmo, E. (2012) · The Journal of Maternal-Fetal & Neonatal Medicine · doi:10.3109/14767058.2012.684168 · Cited by 14 · see citing works

Is the Addition of the Ductus Venosus Useful when Screening for Aneuploidy and Congenital Heart Disease in Fetuses with Normal Nuchal Translucency?

Prats, P., Ferrer, Q., Comas, C., & Rodríguez, I. (2012) · Fetal Diagnosis and Therapy · doi:10.1159/000335489 · Cited by 14 · see citing works

No. 359-Obstetric Ultrasound Biological Effects and Safety

den Hof, M. C. V. (2018) · Journal of Obstetrics and Gynaecology Canada · doi:10.1016/j.jogc.2017.11.023 · Cited by 14 · see citing works

Ultrasound imaging in research and clinical medicine

Schellpfeffer, M. A. (2013) · Birth Defects Research Part C Embryo Today Reviews · doi:10.1002/bdrc.21032 · Cited by 14 · see citing works

Prenatal Sonographic Features of Fetuses in Trisomy 13 Pregnancies (IV)

Chen, C. (2010) · Taiwanese Journal of Obstetrics and Gynecology · doi:10.1016/s1028-4559(10)60002-2 · Cited by 14 · see citing works

First‐trimester ultrasound screening for trisomy 21 based on maternal age, fetal nuchal translucency, and different methods of ductus venosus assessment

Wagner, P., Sonek, J., Klein, J., Hoopmann, M., Abele, H., & Kagan, K. O. (2017) · Prenatal Diagnosis · doi:10.1002/pd.5065 · Cited by 13 · see citing works

First Trimester Ultrasound Assessment for Fetal Aneuploidy

Hyett, J. A., Mogra, R., & Sonek, J. (2014) · Clinical Obstetrics & Gynecology · doi:10.1097/grf.0000000000000013 · Cited by 11 · see citing works

Prospective study evaluating performance of first‐trimester combined screening for trisomy 21 using repeat sampling of maternal serum markers PAPP‐A and free β‐hCG

Ekelund, C. K., Wright, D. E., Ball, S., Kirkegaard, I., Nørgaard, P., Sørensen, S., Friis-Hansen, L. J., Jørgensen, F. S., Tørring, N., Bech, B. H., et al. (2012) · Ultrasound in Obstetrics and Gynecology · doi:10.1002/uog.12266 · Cited by 11 · see citing works

Down Syndrome Prediction Using a Cascaded Machine Learning Framework Designed for Imbalanced and Feature-correlated Data

Li, L., Liu, W., Zhang, H., Jiang, Y., Hu, X., & Liu, R. (2019) · IEEE Access · doi:10.1109/access.2019.2929681 · Cited by 11 · see citing works

Liver volume in trisomy 21 and euploid fetuses at 11 to 13 weeks

Gielchinsky, Y., Zvanca, M. E., Minekawa, R., Persico, N., & Nicolaides, K. H. (2010) · Prenatal Diagnosis · doi:10.1002/pd.2633 · Cited by 11 · see citing works

First trimester genetic sonogram for screening fetal Down syndrome: A population-based study

Traisrisilp, K., Sirichotiyakul, S., Tongprasert, F., Srisupundit, K., Luewan, S., Jatavan, P., Sirilert, S., & Tongsong, T. (2021) · Taiwanese Journal of Obstetrics and Gynecology · doi:10.1016/j.tjog.2021.05.021 · Cited by 10 · see citing works

Maternal prenatal screening programs that predict trisomy 21, trisomy 18, and neural tube defects in offspring

Chen, Y., Ning, W., Shi, Y., Chen, Y., Zhang, W., Li, L., & Wang, X. (2023) · PLoS ONE · doi:10.1371/journal.pone.0281201 · Cited by 10 · see citing works

The frontal space measurement in euploid and aneuploid pregnancies at 11–13 weeks' gestation

Yazdi, B., Riefler, P., Fischmüller, K., Sonek, J., Hoopmann, M., & Kagan, K. O. (2013) · Prenatal Diagnosis · doi:10.1002/pd.4205 · Cited by 10 · see citing works

Likelihood Ratios to Apply for Nasal Bone, Ductus Venosus and Tricuspid Flow at the 11-13 Weeks' Scan in Down Syndrome Screening

Illa, M., Mula, R., Arigita, M., Grande, M., Goncé, A., Borobio, V., & BORRELL, A. (2013) · Fetal Diagnosis and Therapy · doi:10.1159/000351854 · Cited by 10 · see citing works

First trimester sonographic diagnosis of orofacial defects. Review of literature

Trujillo, A. C. S., Rincón-Guio, C., Narváez, L. P. L., Cáceres, J. F., & Charry, J. D. (2019) · The Journal of Maternal-Fetal & Neonatal Medicine · doi:10.1080/14767058.2019.1570114 · Cited by 9 · see citing works

Frontomaxillary facial angle at 11 + 0 to 13 + 6 weeks in Chinese population

Chen, M., Wang, H. F., Leung, T. Y., Sahota, D. S., Borenstein, M., Nicolaides, K. H., Lao, T. T.-H., & Lau, T. K. (2010) · The Journal of Maternal-Fetal & Neonatal Medicine · doi:10.3109/14767058.2010.497881 · Cited by 9 · see citing works

Nichtinvasive Pränataldiagnostik

Eiben, B., Glaubitz, R., & Kagan, K. O. (2014) · Medizinische Genetik · doi:10.1007/s11825-014-0021-3 · Cited by 10 · see citing works

Abnormal Ductus Venosus Flow in First-Trimester Fetuses With Increased Nuchal Translucency

de Mooij, Y. M., Haak, M. C., Bartelings, M. M., Twisk, J. W. R., Groot, A. C. G., van Vugt, J. M. G., & Bekker, M. N. (2010) · Journal of Ultrasound in Medicine · doi:10.7863/jum.2010.29.7.1051 · Cited by 9 · see citing works

Updated Reference Ranges for the Ductus Venosus Pulsatility Index at 11–13 Weeks

Sabrià, J., Comas, C., Barceló‐Vidal, C., García-Posada, R. A., Echevarrı́a, M., Gómez‐Roig, M. D., & BORRELL, A. (2012) · Fetal Diagnosis and Therapy · doi:10.1159/000339413 · Cited by 9 · see citing works

Down syndrome screening using first‐trimester combined tests and contingent use of femur length at routine anomaly scan

Salomon, L. J., Chevret, S., Bussières, L., Ville, Y. G., & Rozenberg, P. (2010) · Prenatal Diagnosis · doi:10.1002/pd.2550 · Cited by 9 · see citing works

Early diagnosis of trisomy 21, trisomy 18 and trisomy�13 using nuchal translucency thickness and ductus venosus blood flow waveform in West China

Tang, Y., Luo, H., Mu, D., Yang, T., Zhu, Q., Yang, F., & Liu, G. (2018) · Molecular Medicine Reports · doi:10.3892/mmr.2018.9756 · Cited by 8 · see citing works

Systematic analysis of the development of the ductus venosus in wild type mouse and human embryos

Burger, N. B., Haak, M. C., de Bakker, B. S., Shaibani, Z. A., de Groot, C. J. M., Christoffels, V. M., & Bekker, M. N. (2013) · Early Human Development · doi:10.1016/j.earlhumdev.2013.07.029 · Cited by 8 · see citing works

Screening for trisomy 21 based on maternal age, nuchal translucency measurement, first trimester biochemistry and quantitative and qualitative assessment of the flow in the DV — the assessment of efficacy

Czuba, B., Zarotyński, D., Dubiel, M., Borowski, D., Węgrzyn, P., Cnota, W., Reska-Nycz, M., Mączka, M., Wielgoś, M., Sodowski, K., et al. (2017) · Ginekologia Polska · doi:10.5603/gp.a2017.0088 · Cited by 8 · see citing works

Analysis of secondary ultrasound markers in the first trimester before chorionic villus sampling

Molina, F. S., Badillo, M. P. C., García, E. A. Z., de Santos, A. G. F., & Ventoso, F. M. (2010) · Prenatal Diagnosis · doi:10.1002/pd.2615 · Cited by 8 · see citing works

First trimester screening and Down syndrome

Marttala, J. (2011) · Cited by 8 · see citing works

Fetal Doppler assessment in pregnancy

Ochoa, J. H., & Cafici, D. (2025) · Best Practice & Research Clinical Obstetrics & Gynaecology · doi:10.1016/j.bpobgyn.2025.102594 · Cited by 7 · see citing works

Combined First Trimester Screening and Cell-Free Fetal DNA -" Next Generation Screening" Kombiniertes Ersttrimesterscreening und zellfreie fetale DNA -" Next Generation Screening"

Kagan, K. O., Eiben, B., & Kozlowski, P. (2014) · Cited by 7 · see citing works

First trimester combined screening for fetal aneuploidies enhanced with additional ultrasound markers: an 8-year prospective study

Nemescu, D., Bratie, A., Mihaila, A., Navolan, D. B., & Tănase, A. E. (2018) · Ginekologia Polska · doi:10.5603/gp.a2018.0035 · Cited by 7 · see citing works

Screening performance for trisomy 21 comparing first trimester combined screening and a first trimester contingent screening protocol including ductus venosus and tricuspid flow

Ekelund, C. K., Petersen, O. B., Sundberg, K., Pedersen, F. H., Vogel, I., & Tabor, A. (2012) · Prenatal Diagnosis · doi:10.1002/pd.3902 · Cited by 7 · see citing works

Are first-trimester screening markers altered in assisted reproductive technologies pregnancies?

Geipel, A., Gembruch, U., & Berg, C. (2011) · Current Opinion in Obstetrics & Gynecology · doi:10.1097/gco.0b013e3283455972 · Cited by 7 · see citing works

The diagnostic value of a detailed first trimester anomaly scan in fetuses with increased nuchal translucency thickness

TEKESIN, I. (2018) · Journal of Perinatal Medicine · doi:10.1515/jpm-2018-0145 · Cited by 7 · see citing works

The Value of Detailed First-Trimester Ultrasound Anomaly Scan for the Detection of Chromosomal Abnormalities

TEKESIN, I. (2018) · Ultraschall in der Medizin - European Journal of Ultrasound · doi:10.1055/a-0640-3148 · Cited by 6 · see citing works

Ultrassonografia obstétrica entre a 11ª e a 14ª semanas: além do rastreamento de anomalias cromossômicas

Peralta, C. F. A., & Barini, R. (2011) · Revista Brasileira Ginecologia e Obstetrícia · doi:10.1590/s0100-72032011000100008 · Cited by 6 · see citing works

Are there characteristics of the false-negative cases from the first trimester combined screening programme for Down syndrome?

Hartwig, T. S., Sørensen, S., & Jørgensen, F. S. (2014) · Current Opinion in Obstetrics & Gynecology · doi:10.1097/gco.0000000000000054 · Cited by 6 · see citing works

Cell-free DNA testing after combined test: factors affecting the uptake

Maíz, N., Alzola, I., Murua, E., & Santos, J. R. (2016) · The Journal of Maternal-Fetal & Neonatal Medicine · doi:10.3109/14767058.2016.1138467 · Cited by 6 · see citing works

First-trimester presentation of ultrasound findings in trisomy 13 and validation of multiparameter ultrasound-based risk calculation models to detect trisomy 13 in the late first trimester

Rajs, B., Nocuń, A., Matyszkiewicz, A., Pasternok, M., Kołodziejski, M., Wiercińska, E., & Wiechec, M. T. (2020) · Journal of Perinatal Medicine · doi:10.1515/jpm-2020-0383 · Cited by 6 · see citing works

Embryology, Ductus Venosus

Sidhu, P. S., & Lui, F. (2019) · StatPearls · Cited by 6 · see citing works

The assessment of nuchal translucency and serum markers for down syndrome screening with ductus venosus Doppler measurements in the first trimester

Özer, Ö., Sayin, C. N., & Varol, F. G. (2010) · Journal of the Turkish-German Gynecological Association · doi:10.5152/jtgga.2010.36 · Cited by 6 · see citing works

Ductus venosus Doppler velocimetry in normal pregnancies from 11 to 13 + 6 weeks' gestation—A Taiwanese study

Tseng, C.-C., Wang, H.-I., Wang, P., Yang, M.-J., Juang, C., Horng, H., Wu, Y., Chen, C.-C., Shiu, H.-L., Chiang, M.-M., et al. (2012) · Journal of the Chinese Medical Association · doi:10.1016/j.jcma.2012.02.015 · Cited by 6 · see citing works

First Trimester Ultrasound Screening: An Update

Sonek, J., Glover, M., Zhou, M., & Nicolaides, K. H. (2010) · Donald School Journal of Ultrasound in Obstetrics & Gynecology · doi:10.5005/jp-journals-10009-1133 · Cited by 6 · see citing works

Prenatal Screening for Neural Tube Defects and Aneuploidy

Sutton, A. L. M., & Biggio, J. (2013) · Elsevier eBooks · doi:10.1016/b978-0-12-383834-6.00032-x · Cited by 6 · see citing works

Invasive Prenatal Diagnostics: A Cornerstone of Perinatal Management

Świetlicki, A., Gutaj, P., Iciek, R., Awdi, K., Paluszkiewicz-Kwarcińska, A., & Wender-Ożegowska, E. (2024) · Applied Sciences · doi:10.3390/app14166915 · Cited by 7 · see citing works

Frontomaxillary Facial Angle Measurement in Screening for Trisomy 18 at 11 + 0 to 13 + 6 Weeks of Pregnancy: A Double-Centre Study

Czuba, B., Cnota, W., Włoch, A., Węgrzyn, P., Sodowski, K., Wielgoś, M., & Borowski, D. (2013) · BioMed Research International · doi:10.1155/2013/168302 · Cited by 5 · see citing works

Influence of nuchal cord on ductus venosus assessment at 11 to 13 + 6 weeks' gestation

Plasencia, W., Lopez, P., Esparza, M., Garcia, R., Barber, M. A., & García, J. Á. (2010) · Ultrasound in Obstetrics and Gynecology · doi:10.1002/uog.7564 · Cited by 5 · see citing works

Nonmedical Use of Ultrasound in Pregnancy: Ethical Issues, Patients' Rights and Potential Misuse

Brezinka, C. (2010) · Ultrasound in Medicine & Biology · doi:10.1016/j.ultrasmedbio.2010.04.004 · Cited by 5 · see citing works

First‐trimester ultrasound screening for trisomy 21 based on maternal age, fetal nuchal translucency, and different methods of ductus venosus assessment

Wagner, P., Sonek, J., Klein, J., Hoopmann, M., Abele, H., & Kagan, K. O. (2017) · Prenatal Diagnosis · doi:10.1002/pd.5065 · Cited by 13 · see citing works

P16.06: First trimester ultrasound screening for Trisomy 21 based on maternal age, fetal nuchal translucency and different methods of ductus venosus assessment

Kagan, K. O., Wagner, P., & Hoopmann, M. (2017) · Ultrasound in Obstetrics and Gynecology · doi:10.1002/uog.18160

Screening for trisomy 21 based on maternal age, nuchal translucency measurement, first trimester biochemistry and quantitative and qualitative assessment of the flow in the DV — the assessment of efficacy

Czuba, B., Zarotyński, D., Dubiel, M., Borowski, D., Węgrzyn, P., Cnota, W., Reska-Nycz, M., Mączka, M., Wielgoś, M., Sodowski, K., et al. (2017) · Ginekologia Polska · doi:10.5603/gp.a2017.0088 · Cited by 8 · see citing works

Ductus venosus assessment at the time of nuchal translucency measurement in the detection of fetal aneuploidy

BORRELL, A., Martínez, J. M., Serés, A., Borobio, V., Cararach, V., & Fortuny, A. (2003) · Prenatal Diagnosis · doi:10.1002/pd.716 · Cited by 80 · see citing works

Screening for aneuploidy in the first trimester by assessment of blood flow in the ductus venosus

Mavrides, E., Sairam, S., Hollis, B., & Thilaganathan, B. (2002) · BJOG An International Journal of Obstetrics & Gynaecology · doi:10.1016/s1470-0328(02)01482-9 · Cited by 74 · see citing works