The Fibroblast Growth Factor signaling pathway

Ornitz, David M., Itoh, Nobuyuki·2015·WIREs Developmental Biology

Cited by (1,019)

Items 901–1,000 of 1,019

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  8. Fibroblast growth factor receptor signaling in head and neck tumors: molecular pathogenesis and potential therapeutic targets.
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  9. Fibroblast growth factor 21 in metabolic dysfunction-associated steatotic liver disease and beyond: from bench to bedside
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  12. Expression of Growth Factor Genes in the Body Wall of the Holothurian Eupentacta fraudatrix During Regenerative Processes
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  14. Identification and validation of NCOA5-ZCCHC3/FGF22 axis as a prognostic marker in lung adenocarcinoma migration and invasion
    Yi-Ran Yu, Wen Jin, Erdun Chaogetu, Xiao-Li Zhang, Xi Liu, Ya-Han Gao, Feng Li, Rila Su · 2026 · Cell Death and Disease
  15. A promising therapeutic strategy reduces abnormal Aβ deposition and inhibits neuronal apoptosis via FGF17 ameliorating AD-like neurodegeneration
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  16. Lineage-specific change in craniofacial gene regulatory networks of syngnathid fishes revealed by integrating multiomics across fishes
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  17. Morphogen Gradients in the Development of the Heart and of the Vascular System.
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  19. Direct Measurements of Differential FGF Binding to Full-Length FGFRs in Plasma Membrane Derived Vesicles.
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  20. Loss of tissue-state plasticity: a conceptual framework for age-associated regenerative failure
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  21. FGFR1 signaling in rheumatoid arthritis: Mechanisms of bone destruction and therapeutic targeting (Review)
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  22. Structure–function relationship in FGF signaling: rational design of highly stable FGF2 variants and their effect on cell growth, metabolism, and survival
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  23. Paracrine Signaling in Cell–Biomaterial Interactions in Scaffold Vascularization: A Mini Review
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  25. Fgf evolution in vertebrates: insights from cyclostomes
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  26. An integrative model of FGF2-induced signaling and muscle cell proliferation.
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  27. ХОНДРОДИСПЛАЗИИ В ДЕТСКОМ ВОЗРАСТЕ: СОВРЕМЕННЫЕ ПРЕДСТАВЛЕНИЯ О МОЛЕКУЛЯРНЫХ МЕХАНИЗМАХ, ДИАГНОСТИКЕ И МУЛЬТИДИСЦИПЛИНАРНОМ ВЕДЕНИИ
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  28. The Role of Biologically Active Materials in Peri-Implant Diseases
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  29. Terminal 4q duplication and extended 10q deletion in a preterm infant with linear growth restriction: transcriptomic evidence of disrupted developmental and metabolic pathways
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  30. Canonical and emerging regulatory mechanisms of tissue remodeling: shared principles across organs and therapeutic opportunities
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  31. Unconventional activation of the proto-oncogene FGFR1 by extracellular phosphate via H2O2-mediated kinase oxidation.
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  32. Adenovirus-mediated co-regulation of Notch, FGF and BMP signaling pathways promotes the regeneration of cochlear hair cells in neonatal mice.
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  33. Network Pharmacological Analysis of Lentinan in Regulating Intervertebral Disc Degeneration: Combined with Machine Learning-Based Screening and Molecular Dynamics Validation
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  34. CD271 Identifies a Subpopulation with Enhanced Neural-like Potential Within Wharton Jelly Derived Mesenchymal Stem/Stromal Cells
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  35. FGFR1-ETV1-CXCL1 signaling in dermal fibroblast orchestrates fibroblast-associated itch.
    Z. Zhong, Na Wei, Dong-Jin Li, Ting-ting Shan, Ya-Ling Song, Xiao‐Liang Wang, Siddhant Zhao, Ya-Ping Liu, Xue-Feng Chen, Huan Wang et al. · 2026 · Proceedings of the National Academy of Sciences of the United States of America
  36. An overview of targeted drug delivery systems specific for fibroblast growth factor receptors and their co-receptors
    Krzysztof Ciura, Natalia Porębska, Ł. Opaliński · 2026 · Expert Opinion on Drug Delivery
  37. A transgenic zebrafish for direct optogenetic activation of FGF/ERK signaling
    W. Anderson, Leanne E. Iannucci, N. Sinaii, Julia Porcino, Katherine W. Rogers · 2026 · bioRxiv
  38. Node properties of biomarkers within the protein–protein interaction network derived from breast cancer-associated genes
    T. Sasaki, Saito Torii · 2026 · PLoS ONE
  39. Enhanced Expansion of Bone Marrow-Derived Mesenchymal Stem Cells on Collagen-Coated Microcarriers Functionalized with Chimeric IGF-1–bFGF Proteins
    Shiina Pasanen, Fumika Abe, Karina Erda Saninggar, I. Hirata, Kotaro Tanimoto, Koichi Kato · 2026 · ACS Omega
  40. Cadmium impairs heart ventricular formation and disrupts polysialylated-NCAM/FGF receptor signaling in Xenopus tadpoles
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  41. Low-grade neuroepithelial tumor with FGFR1::TACC1 fusion: a clinicopathologic analysis of seven cases
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  42. Deciphering MFAP5+ Fibroblasts in Pancreatic Cancer Progression via Multi‐Regional Single‐Cell RNA Sequencing With Experimental Validation
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  43. FGF2 Deficiency Modulates Early Microglial Responses Without Affecting Photoreceptor Survival in a Retinitis Pigmentosa Mouse Model
    Felia C. Haffelder, Nundehui Díaz-Lezama, Zeynep Okutan, Claudia Grothe, Susanne F. Koch · 2026 · Cells
  44. In-silico Identification and Structural Characterization of a Missense Variant (p.Gly380Arg) in the FGFR3 Gene Associated with Achondroplasia
    Sajjal Durrani · 2026 · INTERNATIONAL JOURNAL OF APPLIED AND CLINICAL RESEARCH
  45. The FGF–FGFR axis as an immune–metabolic rheostat in gastrointestinal inflammation and cancer
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  46. The evolving role of futibatinib for advanced cholangiocarcinoma
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  47. Prenatal Variable Expressivity of a Maternal FGFR1 Truncating Variant in Consecutive Pregnancies: A Dual‐Generation Case Report
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  48. Induction of haploid zebrafish and analysis of resultant developmental defects and aberrant gene expression
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  49. Comparative Analysis of Amelogenin-Derived Peptides LRAP and SP on Osteogenic Differentiation of Human Dental Pulp and Bone Marrow-Derived Stem Cells
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  50. Targeting the FGF1/FGFR signaling pathway enhances the antitumor effect of oxaliplatin and alleviates chemotherapy-induced peripheral neuropathy.
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  51. Crizotinib attenuates bleomycin-induced pulmonary fibrosis via regulating fibroblast activation
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  52. Toward Personalized ACS Therapy: How Disease Status and Patient Lifestyle Shape the Molecular Signature of Autologous Conditioned Serum
    C. Bauer, D. Kern, Kalojan Petkin, S. Nehrer · 2026 · Journal of Clinical Medicine
  53. FOXI3 promotes migration and proliferation in prostate cancer bone metastases, modulated by FGF8
    Angana Mukherjee, Daniel P. Hollern, W. Byrd, T. Rayburn, Oluwasina G. Williams, Carrie S. Knight, Clayton Yates, Jacqueline Jones · 2026 · bioRxiv
  54. Fibroblast growth factor receptor inhibitors in glioma: a narrative review of recent advances
    Mingyu Han, Zhao-Kai Zhou, Bi Qian, Yuan-Qi Zhang, Cheng Peng, Fu Peng · 2026 · Frontiers in Pharmacology
  55. Multiplexed Pan Soluble Ligandome Assaying via OASIS
    Yi-Hung Lee, Yesh Doctor, Yifan Zhang, Satheesh Kumar, Joseph Rainaldi, Emily Pan, P. Mali · 2025 · bioRxiv
  56. The role of FGFR and VEGFR signaling pathways in the mechanisms of secondary resistance of gastrointestinal stromal tumors to tyrosine kinase receptor inhibitors
    P. Dunaev, F. I. Mukhutdinova, M. S. Shashina, P. Kopnin, S. Boichuk · 2025 · Advances in Molecular Oncology
  57. Novel heterosteroids induce anabolic effects in human skeletal muscle cells: An integrated analysis of anabolic and catabolic signaling pathways
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  58. Downstream effects of the “Less, but More” Fgf signaling in Oikopleura dioica: Fgf receptor expansion and RTK pathway simplification
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  59. Applications of Platelet-rich Plasma in the Treatment of Dermatological Disorders
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  60. Environmental yin-yang: how external cues are processed at the level of cells and at the level of an organism
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  61. Role of JAM-C in Lens Cell Adhesion, Calcium Homeostasis, and Cataract Pathogenesis.
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  62. Physiological diversity and adaptation of Rhizaria revealed by phylogenomics and comparative transcriptomics
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  63. Preadipocyte Uncoupling Protein 1 Expression Invoked by Fibroblast Growth Factors Imprints on Post‐Differentiation White and Brown Adipocyte Phenotype
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  64. Adipocyte heparan sulfate determines type 2 diabetes susceptibility in mice via FGF1-Mediated glucose regulation
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  65. Subcutaneous Implantation of Exogenous Melatonin Induces a Polarization Effect on the Weight of Scent Glands in Muskrat.
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  66. Generation of human induced pluripotent stem cell lines from patients with FGFR2-linked syndromic craniosynostosis
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  67. Reduced FGF9 Leads to Kidney Injury Through Regulating Renal Tubular Epithelial Cell EMT in Diabetes
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  68. Tissue Engineering in Periodontal Regeneration – A Review
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  69. Association between FGF10 expression and gland-forming differentiation pattern in gastric adenocarcinoma: An immunohistochemical analysis
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  70. Nuclear rerouting of paracrine Fgf3 in source cells represses target genes to pattern morphogen responses
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  71. Fibroblast growth factor 16: Molecular mechanisms, signalling crosstalk, and emerging roles in cardiac biology and metabolic regulation
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  72. The primary cilium as a gatekeeper of FGFR2 function.
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  73. Nephron segmentation and patterning in kidney organoids can be modulated by distinct FGF subfamily members
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  74. Immune infiltration and protective roles of FGF21 in liver injury, obesity, and hepatocellular cancer
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  75. Serum Concentrations of Selected Biological Factors as a Potential Tool for Detecting Recurrence in Endocrine Tumors—A Pilot Study
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  76. Concentration- and time-dependence of phosphorylation events stimulated by fibroblast growth factor-4 (FGF-4) in Rama 27 fibroblasts
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  77. Fibroblast growth factor 7 (FGF7) and its receptor FGFR2IIIb during the peri-implantation period of dromedary camels: A comparative analysis between left and right uterine horns.
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  78. MiRNA-143 Affects Hair Follicle Periodical Development in Cashmere Goats by Down-Regulating FGF9 and MAPK1
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  79. Interplay between cytokine and FGF2 signaling in induction of entosis and vasculogenic mimicry response in glioblastoma
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  80. Role of Fibroblast Growth Factor Pathway Receptor Genes in Breast Cancer
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  81. Study on Robotic Cell Culture Systems for Autonomous Cultivation of Fibroblast Cells
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  82. FOXQ1–FGF10 axis attenuates inflammation in human dental pulp stem cells by suppressing NF-κB signaling
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  83. Active EB1 surges promote tubulin influx into the growing outer segments of the bipartite olfactory cilia in Drosophila
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  84. The Caenorhabditis elegans protein SOC-3 permits an alternative mode of signal transduction by the EGL-15 FGF receptor
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  85. Biomarkers of prostate bladder and testicular cancers: current use in anatomic pathology and future directions
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  86. Mutations in ErbB2 accumulating in the male germline measured by error-corrected sequencing
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  87. Fibroblast growth factors-An introduction to our primer series.
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  88. Cord Blood as a Trophic-Growth Additive for Culture Work
    A. Goncharov, V. Shupletsova, N. D. Gazatova, O. Melashchenko, K. Yurova, L. S. Litvinova · 2024 · Cell and Tissue Biology
  89. Differential effects of the N‐terminal helix of FGF8b on the activity of a small‐molecule FGFR inhibitor in cell culture and for the extracellular domain of FGFR3c in solution
    Konstantin S. Mineev, B. Hargittay, Jing Jin, Claudia Catapano, M. Dietz, M. Segarra, Mark Harwardt, C. Richter, H. R. Jonker, K. Saxena et al. · 2024 · FEBS Letters
  90. FGF1.
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  91. Risk of congenital anomalies in children who have a sibling with cancer: a matched cohort study.
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  92. Umbilical blood as a trophic-growth supplement for cultural work
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  93. Common modes of ERK induction resolve into context specific signalling via a combination of signal duration and cell type specific transcriptional repression
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  94. Effect of Estradiol on Carbohydrate-Fat Metabolism and FGF21 System Activity in Female C57BL/6 Mice with Short-Term Consumption of the Cafeteria Diet
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  95. The role of fibroblast growth factor-2 in the development of bronchopulmonary dysplasia in very and extremely low birth weight infants
    P. Kiciński, B. Małachowska, K. Wyka, Ewa Gulczyńska · 2023 · Pediatria i Medycyna Rodzinna
  96. SIK2: A novel negative feedback regulator of FGF signaling
    Gamze Kuser-Abali, Asli Ugurlu-Bayarslan, Yeliz Yilmaz, F. Ozcan, Funda Karaer, K. Buğra · 2023 · bioRxiv
  97. Serum pentraxin and E-selectin levels are associated with outcomes in patients with acute myocardial infarction who undergo percutaneous coronary intervention
    Wiktoria Smyła, Sebastian Krych, Michał Jurkiewicz, Z. Czuba, M. Skrzypek, P. Piłat, M. Gąsior, B. Szyguła-Jurkiewicz · 2023 · Medical Research Journal
  98. FGF18.
    Michael G.E. Goldschagg, Dorit Hockman · 2023 · Differentiation; research in biological diversity
  99. The spontaneous mouse mutant low set ears (Lse) is caused by tandem duplication of Fgf3 and Fgf4
    Alana Luzzio, Sarah Edie, K. Palmer, L. B. Caddle, Rachel Urban, L. Goodwin, Ian C. Welsh, L. Reinholdt, David E. Bergstrom, T. Cox et al. · 2023 · Mammalian Genome
  100. FRS2-independent GRB2 interaction with FGFR2 is not required for embryonic development
    James F. Clark, P. Soriano · 2023 · bioRxiv