The Fibroblast Growth Factor signaling pathway

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Items 101–200 of 1,019

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6. FGFR3 alterations in bladder cancer: Sensitivity and resistance to targeted therapies
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7. Fibroblast growth factor 18 stimulates the proliferation of hepatic stellate cells, thereby inducing liver fibrosis
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10. Roles of the fibroblast growth factor signal transduction system in tissue injury repair
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11. Apoptotic stress-induced FGF signalling promotes non-cell autonomous resistance to cell death
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12. Fgf9 regulates bone marrow mesenchymal stem cell fate and bone-fat balance in osteoporosis by PI3K/AKT/Hippo and MEK/ERK signaling
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13. FGF, Mechanism of Action, Role in Parkinson’s Disease, and Therapeutics
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14. FGF/FGFR Pathways in Multiple Sclerosis and in Its Disease Models
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15. Disruption of sugar nucleotide clearance is a therapeutic vulnerability of cancer cells
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16. Phosphate-sensing and regulatory mechanism of FGF23 production
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17. Metabolic Messengers: fibroblast growth factor 1
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18. The computational capabilities of many-to-many protein interaction networks
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19. ERK-mediated Curvature Feedback Regulates Branching Morphogenesis in Lung Epithelial Tissue
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20. Time-integrated BMP signaling determines fate in a stem cell model for early human development
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22. Novel targetable FGFR2 and FGFR3 alterations in glioblastoma associate with aggressive phenotype and distinct gene expression programs
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23. The role of microglial activation on ischemic stroke: Modulation by fibroblast growth factors
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24. RTK Inhibitors in Melanoma: From Bench to Bedside
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25. Optimization of Vascularized Intestinal Organoid Model
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26. B3GALT6 Promotes Dormant Breast Cancer Cell Survival and Recurrence by Enabling Heparan Sulfate-Mediated FGF Signaling
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27. Gene expression dynamics underlying cell fate emergence in 2D micropatterned human embryonic stem cell gastruloids
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28. Discovery of TYRA-300: First Oral Selective FGFR3 Inhibitor for the Treatment of Urothelial Cancers and Achondroplasia.
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29. Structure-based drug-development study against fibroblast growth factor receptor 2: molecular docking and Molecular dynamics simulation approaches
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30. FGFR redundancy limits the efficacy of FGFR4-selective inhibitors in hepatocellular carcinoma
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31. Endothelial FGF signaling is protective in hypoxia-induced pulmonary hypertension.
    Kel Vin Woo, Isabel Y. Shen, C. Weinheimer, A. Kovács, Jessica Nigro, Chieh-Yu Lin, Murali M. Chakinala, D. Byers, D. Ornitz · 2021 · Journal of Clinical Investigation
32. FGFR3 phosphorylates EGFR to promote cisplatin-resistance in ovarian cancer.
    Jing Zhao, Wenxi Tan, Lingyi Zhang, Jian Liu, Mengyuan Shangguan, Junyu Chen, Ben-Zheng Zhao, Yuanqing Peng, Man-Hua Cui, Shuhua Zhao · 2021 · Biochemical Pharmacology
33. FGF21 and Chronic Kidney Disease.
    J. Salgado, M. A. Goes, N. Salgado · 2021 · Metabolism: Clinical and Experimental
34. Glucagon receptor signaling regulates weight loss via central KLB receptor complexes
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35. Granulosa Cells: Central Regulators of Female Fertility
    L. F. Schütz, I. Batalha · 2024 · Endocrines
36. Emerging roles of PLCγ1 in endothelial biology
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37. Mesenchymal stem cells for cartilage regeneration: Insights into molecular mechanism and therapeutic strategies.
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38. Exploring the Role of the Gut and Intratumoral Microbiomes in Tumor Progression and Metastasis
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39. Biological and clinical implications of FGFR aberrations in paediatric and young adult cancers
    Lauren M. Brown, Paul G. Ekert, Emmy D.G. Fleuren · 2023 · Oncogene
40. Osteomalacia in Adults: A Practical Insight for Clinicians
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41. The role of BMP4 in adipose-derived stem cell differentiation: A minireview
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42. Regulation of aromatase in cancer
    Deborah Molehin, Fahmida Akter Rasha, Rakhshanda Layeequr Rahman, Kevin Pruitt · 2021 · Molecular and Cellular Biochemistry
43. Relationships of serum FGF23 and α-klotho with atherosclerosis in patients with type 2 diabetes mellitus
    Jiao Bi, Mei Zheng, Ke Li, Siwei Sun, Zihang Zhang, Nana Yan, Xueping Li · 2024 · Cardiovascular Diabetology
44. The Molecular Mechanisms of Systemic Sclerosis-Associated Lung Fibrosis
    Joe E. Mouawad, Carol A. Feghali‐Bostwick · 2023 · International Journal of Molecular Sciences
45. Targeting FGFR2 Positive Gastroesophageal Cancer: Current and Clinical Developments
    A. Gordon, Edwina Johnston, David K. Lau, N. Starling · 2022 · OncoTargets and Therapy
46. From Fragment to Lead: De Novo Design and Development toward a Selective FGFR2 Inhibitor.
    Lewis D Turner, C. Trinh, Ryan A Hubball, Kyle M Orritt, Chi-Chuan Lin, J. Burns, M. Knowles, C. Fishwick · 2021 · Journal of Medicinal Chemistry
47. Mechanisms of endocrine resistance in hormone receptor-positive breast cancer
    Yuan Gao, Yang Yu, Mingqing Zhang, Wenjun Yu, Lihua Kang · 2024 · Frontiers in Oncology
48. Fibroblast growth factor signaling in axons: from development to disease
    Diogo Tomé, Marta S. Dias, Joana Correia, Ramiro D. Almeida · 2023 · Cell Communication and Signaling
49. The Novel GlycoPEGylated FGF21 Analog Pegozafermin Activates Human FGF Receptors and Improves Metabolic and Liver Outcomes in Diabetic Monkeys and Healthy Human Volunteers
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50. Fibroblast Growth Factor-21 as a Potential Therapeutic Target of Nonalcoholic Fatty Liver Disease
    Dimitrios D. Raptis, C. Mantzoros, S. Polyzos · 2023 · Therapeutics and Clinical Risk Management
51. Jack of all trades, master of each: the diversity of fibroblast growth factor signalling in eye development
    Neoklis Makrides, Qian Wang, C. Tao, Samuel Schwartz, Xin Zhang · 2021 · Open Biology
52. Roles of the FGF-FGFR Signaling System in Cancer Development and Inflammation
    A. Wiedlocha, E. Haugsten, M. Zakrzewska · 2021 · Cells
53. Targeting FGFR in intrahepatic cholangiocarcinoma [iCCA]: leading the way for precision medicine in biliary tract cancer [BTC]?
    Gabriella Aitcheson, A. Mahipal, Binu V. John · 2021 · Expert Opinion on Investigational Drugs
54. CRISPR Screening Identifies Mechanisms of Resistance to KRASG12C and SHP2 Inhibitor Combinations in Non-Small Cell Lung Cancer
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55. Photobiomodulation at 660 nm Stimulates In Vitro Diabetic Wound Healing via the Ras/MAPK Pathway
    Patricia Kasowanjete, H. Abrahamse, N. Houreld · 2023 · Cells
56. FGF2-primed 3D spheroids producing IL-8 promote therapeutic angiogenesis in murine hindlimb ischemia
    Jungkyu Choi, Wooshik Choi, Yunji Joo, H. Chung, Dokyun Kim, S. Oh, Sang-Heon Kim · 2021 · npj Regenerative Medicine
57. Role of Klotho in Hyperglycemia: Its Levels and Effects on Fibroblast Growth Factor Receptors, Glycolysis, and Glomerular Filtration
    M. Typiak, Tomasz Kulesza, P. Rachubik, D. Rogacka, Irena Audzeyenka, S. Angielski, M. Saleem, A. Piwkowska · 2021 · International Journal of Molecular Sciences
58. Fgf10/Fgfr2b Signaling Orchestrates the Symphony of Molecular, Cellular, and Physical Processes Required for Harmonious Airway Branching Morphogenesis
    Matthew R. Jones, Lei Chong, S. Bellusci · 2021 · Frontiers in Cell and Developmental Biology
59. Molecular Targeting of the Fibroblast Growth Factor Receptor Pathway across Various Cancers
    K. Shan, Shivani Dalal, N. N. Thaw Dar, Omani McLish, M. Salzberg, Brian Pico · 2024 · International Journal of Molecular Sciences
60. Small Extracellular Vesicle‐Derived vWF Induces a Positive Feedback Loop between Tumor and Endothelial Cells to Promote Angiogenesis and Metastasis in Hepatocellular Carcinoma
    S. W. Wong, S. K. Tey, X. Mao, Hiu-Ling Fung, Zhi-Jie Xiao, D. Wong, Lung-Yi Mak, Man-Fung Yuen, I. Ng, Jing-Ping Yun et al. · 2023 · Advancement of science
61. Mechanisms of skeletal muscle-tendon development and regeneration/healing as potential therapeutic targets.
    Yuki Yoshimoto, Y. Oishi · 2023 · Pharmacology and Therapeutics
62. Challenges and progress toward tumor-targeted therapy by systemic delivery of polymer-complexed oncolytic adenoviruses
    Thavasyappan Thambi, JinWoo Hong, Arum R. Yoon, Chae‐Ok Yun · 2022 · Cancer Gene Therapy
63. Single-cell RNA analysis identifies pre-migratory neural crest cells expressing markers of differentiated derivatives
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64. Targeting fibroblast growth factor receptors to combat aggressive ependymoma
    D. Lötsch, D. Kirchhofer, B. Englinger, Li Jiang, K. Okonechnikov, D. Senfter, A. Laemmerer, L. Gabler, C. Pirker, A. Donson et al. · 2021 · Acta Neuropathologica
65. Rho-Kinase 1/2 Inhibition Prevents Transforming Growth Factor-β-Induced Effects on Pulmonary Remodeling and Repair
    Xin-Hui Wu, V. Verschut, M. Woest, J. Ng-Blichfeldt, Á. Matías, G. Villetti, A. Accetta, F. Facchinetti, R. Gosens, L. Kistemaker · 2021 · Frontiers in Pharmacology
66. Revolutionizing Wound Healing: Exploring Scarless Solutions through Drug Delivery Innovations.
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67. Spatial profiling of cancer-associated fibroblasts of sporadic early onset colon cancer microenvironment
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68. A Review of Photobiomodulation on PI3K/AKT/mTOR in Wound Healing
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69. The FGF/FGFR system in the microglial neuroinflammation with Borrelia burgdorferi: likely intersectionality with other neurological conditions
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70. Therapeutic Targeting of FGFR Signaling in Head and Neck Cancer
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71. Spatially resolved phosphoproteomics reveals fibroblast growth factor receptor recycling-driven regulation of autophagy and survival
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72. KLF17 promotes human naïve pluripotency but is not required for its establishment
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73. FGF10 and Lipofibroblasts in Lung Homeostasis and Disease: Insights Gained From the Adipocytes
    Yuqing Lv, Qhaweni Dhlamini, Cheng-Shui Chen, Xiao-Kun Li, S. Bellusci, Jin-San Zhang · 2021 · Frontiers in Cell and Developmental Biology
74. Advances of Fibroblast Growth Factor/Receptor Signaling Pathway in Hepatocellular Carcinoma and its Pharmacotherapeutic Targets
    Haijun Wang, Jie Yang, Ke Zhang, Jia Liu, Yushan Li, Wei Su, Na Song · 2021 · Frontiers in Pharmacology
75. The roles of FGFR3 and c-MYC in urothelial bladder cancer
    D. E. Bogale · 2024 · Discover Oncology
76. Menin directs regionalized decidual transformation through epigenetically setting PTX3 to balance FGF and BMP signaling
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77. Fibroblast Growth Factor Receptor (FGFR) Signaling in GIST and Soft Tissue Sarcomas
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78. Fibroblast growth factor 11 (FGF11) promotes non-small cell lung cancer (NSCLC) progression by regulating hypoxia signaling pathway
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79. Fibroblast growth factor 10 reverses cigarette smoke- and elastase-induced emphysema and pulmonary hypertension in mice
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80. Fibroblast growth factor 10 ameliorates neurodegeneration in mouse and cellular models of Alzheimer's disease via reducing tau hyperphosphorylation and neuronal apoptosis
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81. New advances in the research of clinical treatment and novel anticancer agents in tumor angiogenesis
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82. Integrated regulation of chondrogenic differentiation in mesenchymal stem cells and differentiation of cancer cells
    Xiaohui Yang, S. Tian, Lin-Lin Fan, Rui Niu, Man Yan, Shuo Chen, Minying Zheng, Shi-Wu Zhang · 2022 · Cancer Cell International
83. Repression of Osmr and Fgfr1 by miR-1/133a prevents cardiomyocyte dedifferentiation and cell cycle entry in the adult heart
    M. Valussi, J. Besser, Katharina Wystub-Lis, S. Zukunft, M. Richter, T. Kubin, T. Boettger, T. Braun · 2021 · Science Advances
84. Receptor clustering by a precise set of extracellular galectins initiates FGFR signaling
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85. Fibroblast growth factor-2 bound to specific dermal fibroblast-derived extracellular vesicles is protected from degradation
    I. Petit, Ayelet Levy, S. Estrach, C. Féral, A. Trentin, F. Dingli, D. Loew, J. Qu, H. Zhou, C. Théry et al. · 2022 · Scientific Reports
86. Cranial Base Synchondrosis: Chondrocytes at the Hub
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87. AZD4547 targets the FGFR/Akt/SOX2 axis to overcome paclitaxel resistance in head and neck cancer
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88. The Multiple Roles of Fibroblast Growth Factor in Diabetic Nephropathy
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89. Tyrosine kinases in the pathogenesis of tissue fibrosis in systemic sclerosis and potential therapeutic role of their inhibition
    Fabian A. Mendoza, Sonsoles Piera-Velázquez, Sergio A. Jiménez · 2021 · Translational research
90. Investigating underlying molecular mechanisms, signaling pathways, emerging therapeutic approaches in pancreatic cancer
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91. Protein-modified nanomaterials: emerging trends in skin wound healing
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92. FGF12 is a novel component of the nucleolar NOLC1/TCOF1 ribosome biogenesis complex
    Martyna Sochacka, Radoslaw Karelus, Lukasz Opalinski, D. Krowarsch, Martyna Biaduń, J. Otlewski, M. Zakrzewska · 2022 · Cell Communication and Signaling
93. The Effects of FGF4 Retrogenes on Canine Morphology
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94. FGF signalling facilitates cervical cancer progression
    Hiba-Tun-Noor A. Mahmood, Elena Tomás-Bort, A. J. Walker, R. Grose, A. Chioni · 2021 · The FEBS Journal
95. Selective FGFR/FGF pathway inhibitors: inhibition strategies, clinical activities, resistance mutations, and future directions
    M. Repetto, E. Crimini, F. Giugliano, S. Morganti, C. Belli, G. Curigliano · 2021 · Expert Review of Clinical Pharmacology
96. Human ribonuclease 1 serves as a secretory ligand of ephrin A4 receptor and induces breast tumor initiation
    Heng-Huan Lee, Ying-Nai Wang, Wen-Hao Yang, W. Xia, Yong-Kun Wei, Li-Chuan Chan, Yu-Han Wang, Zhou Jiang, Shouping Xu, Jun Yao et al. · 2021 · Nature Communications
97. Fibroblast growth factor 10 attenuates chronic obstructive pulmonary disease by protecting against glycocalyx impairment and endothelial apoptosis
    Tian-Rong Jiang, Weiping Hu, Shao-Yuan Zhang, Changhao Ren, Si-Yun Lin, Zhenyu Zhou, Hao Wu, Jun Yin, L. Tan · 2022 · Respiratory Research
98. Fibroblast growth factor signalling influences homologous recombination-mediated DNA damage repair to promote drug resistance in ovarian cancer
    H. A. Nicholson, Lynne Sawers, R. Clarke, K. Hiom, M. Ferguson, Gillian Smith · 2022 · British Journal of Cancer
99. Targeted therapies: Expanding the role of FGFR3 inhibition in urothelial carcinoma.
    Z. Zengin, A. Chehrazi-Raffle, N. Salgia, R. Muddasani, Sana Ali, L. Meza, S. Pal · 2021 · Urologic oncology
100. Association of FGF‐19 and FGF‐21 levels with primary sarcopenia
     Rabia Bağ Soytaş, Veysel Suzan, Pınar Arman, Tuğçe Emiroğlu Gedik, Damla Unal, M. Cengiz, I. Bolayırlı, Deniz Suna Erdinçler, A. Doventas, H. Yavuzer · 2021 · Geriatrics & Gerontology International