Efficacy and safety of deep transcranial magnetic stimulation for major depression: a prospective multicenter randomized controlled trial

Levkovitz, Yechiel, Isserles, Moshe, Padberg, Frank, Lisanby, Sarah H., Bystritsky, Alexander, Xia, Guohua, Tendler, Aron, Daskalakis, Zafiris J. +17 more·2015·World Psychiatry
DOI 10.1002/wps.20199

Cited by (439)

Items 301–400 of 439

  1. Treating Clinical Depression with Repetitive Deep Transcranial Magnetic Stimulation Using the Brainsway H1-coil
    David Feifel, Katherine Pappas · 2016 · Journal of Visualized Experiments
  2. Can brain stimulation enhance cognition in clinical populations? A critical review
    Donel M Martin, Marian E. Berryhill, Victoria Dielenberg · 2022 · Restorative Neurology and Neuroscience
  3. Music combined with Transcranial Magnetic Stimulation for the treatment of depression
    Irakli Mania, Jagdeep Kaur · 2020 · Music and Medicine
  4. Transcranial magnetic stimulation
    Yiftach Roth, Gaby S. Pell, Abraham Zangen · 2015
  5. Mixing Apples and Oranges in Assessing Outcomes of Repetitive Transcranial Stimulation Meta-Analyses
    André R. Brunoni, Martijn Arns, Chris Baeken, Daniel M. Blumberger, Jérôme Brunelin, Linda L. Carpenter, Jonathan H. Downar, Daniel Keeser, Berthold Langguth, Fady Rachid et al. · 2019 · Psychotherapy and Psychosomatics
  6. Efficacy and Safety of Deep Transcranial Magnetic Stimulation Versus High-Frequency Repetitive Transcranial Magnetic Stimulation for Major Depressive Disorder: A Systematic Review
    Nan Zhang, Yu Mo, Xian-Jun Lan, Qi-Man Liu, Wen-Xiu Li, Xingbing Huang, Huawang Wu, Shi-Chao Xu, Shuochao Li, Xin-Hu Yang et al. · 2024 · Current Behavioral Neuroscience Reports
  7. A New Era for Esketamine in Managing Treatment-Resistant Depression: A Systematic Review of Its Use From Adjunct to First-Line Therapy
    Bhavya, Srijan Shetty, Balakrishnan Sadasivam · 2025 · Cureus
  8. ExoTMS transcranial magnetic stimulation for the reduction of binge eating symptoms
    David Pánek, Toni Slavchev Donchev · 2025 · Psychiatry and Clinical Neurosciences Reports
  9. Substance Use and Antidepressant Response to Transcranial Magnetic Stimulation in Major Depressive Disorder
    Dra Mireya González, Tagalsir Osama, Simon Vandekar, Kwang‐Hyun Hur, J H Brown, Heather Burrell Ward · 2026 · Journal of Affective Disorders
  10. Noninvasive Delivery of Biologicals to the Brain
    Sheldon Jordan, Margaret A. Zielinski, Marcin Kortylewski, Taylor P. Kuhn, Alexander Bystritsky · 2022 · FOCUS The Journal of Lifelong Learning in Psychiatry
  11. Chapter 30. Brain Stimulation Therapies
    Corey J. Keller, Mahendra Takashi Bhati, Jonathan H. Downar, Amit Etkin · 2019 · American Psychiatric Association Publishing eBooks
  12. Investigation of how stimulation intensity of rTMS affects magneto permeabilization of the Blood–Brain Barrier (BBB)
    Behrouz Vejdani Afkham, Zeinab Shankayi, Farideh Bahrami, Seyed Mohammad Firoozabadi, Sahel Heydarheydari, Mohammad Taghi Mohammadi · 2022 · Electromagnetic Biology and Medicine
  13. Modulation of Alcohol Use Disorder by Brain Stimulation
    Noam Barnea‐Ygael, Abraham Zangen · 2024 · Current topics in behavioral neurosciences
  14. Deep transcranial magnetic stimulation for adolescents with treatment-resistant depression: Behavioral and neural correlates of clinical improvement
    Aparna U. Nair, Bonnie Klimes‐Dougan, Thanharat Silamongkol, Zeynep Başgöze, Donovan J. Roediger, Bryon A. Mueller, Christina Sophia Albott, Paul E. Croarkin, Kelvin O. Lim, Alik S. Widge et al. · 2024 · Journal of Affective Disorders
  15. Predictors of dropout from TMS for treatment resistant depression
    Robert Hickson, Kayla Huynh, Linden B. Aly, Jerome Albert Yesavage, Noah S. Philip, Frank Andrew Kozel, Michelle R. Madore · 2025 · Transcranial magnetic stimulation .
  16. Interhemispheric paired associative stimulation targeting the bilateral prefrontal cortex of subjects with obesity and food addiction modulates food-related emotional reactivity and associated brain activity
    Roni Aviram-Friedman, Uri Alyagon, Lior Kafri, Shahar Atias, Abraham Zangen · 2025 · Appetite
  17. Autism Spectrum Disorder
    Shibin Wang, Linyan Fu, Jinming Liu, Min Dong, Fan Yang · 2025 · Springer eBooks
  18. Post-traumatic Stress Disorder
    Sha Sha, Sixiang Liang, Yannan Deng, Leyi Zhu, Xin Chen, Qinge Zhang · 2025 · Springer eBooks
  19. Recent Developments in Noninvasive Neuromodulation for Mood and Anxiety Disorders
    Yu-Pei Hu, Gopalkumar Rakesh, Sarah Hollingsworth Lisanby · 2015 · Current Behavioral Neuroscience Reports
  20. A repetitív transcranialis mágneses stimuláció szerepe a mentális zavarok, elsősorban a terápiarezisztens major depresszív zavar kezelésében
    Róbert Pilisi, Tamás Tényi, András Büki, Norbert Kovács, Antal Tamás Zemplenyi, Gabriella Sebestyén, Péter Osváth, Sándor Fekete, Viktor Vörös · 2019 · Orvosi Hetilap
  21. Treating Clinical Depression with Repetitive Deep Transcranial Magnetic Stimulation Using the Brainsway H1-coil
    David Feifel, Katherine Pappas · 2016 · Journal of Visualized Experiments
  22. Funktionelle Neuroanatomie der Depression
    Thomas Kammer · 2022 · Nervenheilkunde
  23. Repetitive Transcranial Magnetic Stimulation (rTMS) with Traditional Chinese Medicine for Depression: Study Protocol for A Pragmatic Randomized Controlled Trial
    Wenting Liu, Hui Li, Yiting Lu, Jie Yuan, Rongyuan Yang, Lu Zhang, Fei Chen, Yaling Lei, Qing Liu · 2022 · Exploratory Research and Hypothesis in Medicine
  24. Effects of rTMS in Postpartum Depression: A Meta-Analysis
    Tao Wang, Hongxia Wu, Yi Jiang, Wei Hsuan Huang, Dong Yu, Xiao Zhang, Qiwen Mu · 2022 · The Journal for Nurse Practitioners
  25. Personalized electric field simulations of deformable large TMS coils based on automatic position and shape optimization
    Torge Worbs, Bianka Rumi, Kristoffer Hougaard Madsen, Axel Thielscher · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  26. The Heart’s Electromagnetic Field in Emotions, Empathy and Human Connection: Biosensor-Derived Insights into Heart–Brain Axis Mechanisms and a Basis for Novel BioMagnetoTherapies
    Palantzas, Andreas, Anagnostouli, Maria · 2026 · Sensors
  27. Efficacy of TMS and Cognitive Training in Mild Cognitive Impairment: A Pilot Study
    Flavia Mattioli, Chiara Stampatori, Alice Belleri, Michela Pignoli · 2021 · Journal of Neurology Research Review & Reports
  28. Role of Electroconvulsive Therapy, Ketamine Infusion, and Deep Repetitive Transcranial Magnetic Stimulation in Treatment-Resistant Bipolar Depression: A Case Report
    Keming Gao · 2024 · Medicina
  29. Is Theta Burst Stimulation Ready as a Clinical Treatment for Bipolar Disorder?
    Yufei Wu, Danni Yan, Jianli Yang · 2025 · Bipolar Disorders
  30. Comparative efficacy of deep transcranial magnetic stimulation versus repetitive transcranial magnetic stimulation in improving lower extremity motor function in subacute stroke patients
    Chengshuo Wang, Linli Zhang, Mingyue Liu, Anjun Xiang, Jingman Qi, Yuru Fu, Ruoxuan Zhao, Zheyu Xiong, Liang Wu, Qin Zhang · 2025 · Frontiers in Aging Neuroscience
  31. Feasibility and Tolerability of Novel Deep Repetitive Transcranial Magnetic Stimulation for Depression in Older Adults: DIVINE Pilot Study
    Dante G.G. Duarte, Anne-Marie Di Passa, Carly McIntyre‐Wood, Emily MacKillop, Shelby Prokop-Millar, Horodjei Yaya, Allan J. Fein, Emily Vandehei, Jane DeJesus, Benicio Noronha Frey et al. · 2025 · American Journal of Geriatric Psychiatry
  32. An exploratory randomized, double-blind trial of accelerated deep TMS for patients with suicidal thoughts and behaviors
    Esther Bloemhof‐Bris, Yossi Levi‐Belz, Adi Tamary Guterman, Gay Wexler, Sigalit Noam, Shiri Cohen, Kfir Feffer · 2025 · Journal of Affective Disorders
  33. Comparison of rTMS and dTMS in TRD: evidence gaps, cost-effectiveness, and ethical priorities
    Walter Paganin · 2026 · Frontiers in Psychiatry
  34. Trajectories of patient-rated baseline-severe depressive symptoms during repetitive transcranial magnetic stimulation (rTMS) for major depressive disorder
    Evan Hy Einstein, Thomas E. Valles, Cole Citrenbaum, Juliana Corlier, Raghav Gupta, Doan Ngo, Cole D. Matthews, Hrag Peltekian, Hope Hawkins, Hanadi Ajam Oughli et al. · 2026 · Transcranial magnetic stimulation .
  35. Effects of Deep Transcranial Magnetic Stimulation on Cognitive Function in Bipolar Depression: A Randomized Controlled Trial Using the MATRICS Consensus Cognitive Battery
    Lijun Chu, Xiaoju Jia, Ping Gao, Xia Sun, Jian Zhang, Ding Yu, Shiwang Chen, Fuyou Bi, Chuhao Zhang, Dazhi Li et al. · 2026 · ALPHA PSYCHIATRY
  36. Bilateral Theta-Burst Stimulation of Dorsolateral Prefrontal Cortex Regions for Late-Life Depression: A Randomized, Sham-Controlled Clinical Trial.
    Lane Valiengo Leandro da Costa, B. Pinto, M. Luethi, Leonardo Afonso Santos, R. Benatti, M. Lessa, J. Loureiro, J. F. Silva, Lisiane Martins, Pedro Sudbrack-Oliveira et al. · 2026 · American Journal of Psychiatry
  37. Comparison of the clinical efficacy, safety and EEG functional connectivity changes between 18-Hz rTMS and iTBS of accelerated dTMS treatment for major depressive disorder: a randomized controlled trial
    Lulu Yang, Haiyue Dai, Mingjie Zhu, Feng Mengtai, Shuhang Li, J L Wang, Zhangyuan Wang, Huicong Ren, Mengmeng Zhang, Shina Gu et al. · 2026 · Molecular Psychiatry
  38. Early relapse treatment (ERT) or “maintenance” transcranial magnetic stimulation (TMS)?
    SAXBY A. PRIDMORE, Sheila Erger, Marzena Rybak, Erin Kelly, Fiona Lawson · 2017 · UTAS Research Repository
  39. The Value of Neuroimaging for Treating Depression with Brain Stimulation
    Verena Sarrazin, Jacinta O’Shea · 2021 · Springer eBooks
  40. Depressive Störungen
    Gerd Laux · 2017 · Springer eBooks
  41. Neuroinnovation in Medicine: History and Future
    Octavio Choi · 2023 · Springer eBooks
  42. Transcranial magnetic stimulation in psychiatric disorders
    Shixie Jiang, Andrew M. Fukuda, Meghan A. Gonsalves, Brian C. Kavanaugh, Linda L. Carpenter · 2024 · Elsevier eBooks
  43. A History of Transcranial Magnetic Stimulation
    Sean D. Reeves, Zhi‐De Deng, Jonathan R. Young · 2025 · Advances in neuroethics
  44. Stimulating the brain: a primer
    Enrico Opri, Stephanie Cernera · 2025 · Elsevier eBooks
  45. Update on Transcranial Magnetic Stimulation for Depression and Other Neuropsychiatric Illnesses
    Jonathan Essary Becker, Christopher Todd Maley, Elizabeth K.B. Shultz, Warren D. Taylor · 2016 · Psychiatric Annals
  46. Creative Hyper-Activation in Depression
    Leon S. Brenner · 2019 · Creativity Research Journal
  47. Estimulação magnética transcraniana: o que o psiquiatra deve saber?
    María Cristina Montenegro, Amaury Cantilino · 2016 · Debates em Psiquiatria
  48. Maintenance and Continuation Treatment
    Paul Bernard Fitzgerald, Zafiris Jeff Daskalakis · 2022 · Springer eBooks
  49. Preliminary Report of the Safety and Tolerability of 1 Hz Repetitive Transcranial Magnetic Stimulation in Temporal Lobe Epilepsy
    Roman Gersner, Lindsay M. Oberman, Maria J Sanchez, Nicolas Chiriboga, Harper Lee Kaye, Álvaro Pascual‐Leone, Abraham Zangen, Alexander Rotenberg · 2022 · Journal of Central Nervous System Disease
  50. Reply to the Letter to the Editor: “Mixing Apples and Oranges in Assessing Outcomes of Repetitive Transcranial Stimulation Meta-Analyses”
    Ali Amad, Renaud Jardri, Chloé Rousseau, Yann Larochelle, John P. A. Ioannidis, Florian Naudet · 2020 · Psychotherapy and Psychosomatics
  51. Advances in the Application of Electroconvulsive Therapy
    Douglas D’Agati, Irving Michael Reti · 2016 · Current Behavioral Neuroscience Reports
  52. Repetitive Transcranial Magnetic Stimulation in Major Depression
    Hiroê Alencar Braga, Ákila Macêdo Freire, Ageu de Oliveira Saraiva, Alisson Cordeiro Moreira, Flaviane Cristine Troglio da Silva, Modesto Leite Rolim Neto · 2016 · Journal of Neurology and Neuroscience
  53. Varied Antidepressant Response and Subjective Experience Across 3 Different Repetitive Transcranial Magnetic Stimulation Devices
    Carter Paul, Álvaro Pascual‐Leone, Adam Philip Stern · 2017 · Journal of Ect
  54. Commentary. Transcranial Magnetic Stimulation: Does It Matter Where or What or Whom You Target?
    JOSHUA BERMAN · 2017 · Journal of Psychiatric Practice
  55. Effect of Repetitive Transcranial Magnetic Stimulation on the Structural and Functional Connectome in Patients with Major Depressive Disorder
    G. Asturias · 2017 · DukeSpace (Duke University)
  56. Nicht-invasive Stimulationsverfahren in der Psychiatrie am Beispiel der Transkraniellen Magnetstimulation (TMS)
    Nora Behler, Irmgard Hantschk, Linda Wulf, Ulrich Palm, Oliver Michael Pogarell, Frank Padberg · 2017 · Das Neurophysiologie-Labor
  57. Behind the Screen: –Internet-Based Cognitive Behavioural Therapy to Treat Depressive Symptoms in Persons with Heart Failure
    Johan Lundgren · 2017
  58. Ready, Set, Action: Potential Breakthrough Therapy for Treatment-Resistant Depression
    Alvin Garlejo · 2017 · USF Scholarship Repository (University of San Francisco)
  59. The Application of Brain Stimulation in Psychiatric Disorders : An Overview
    Daeyoung Dave Roh, Lee Young Kang, Kim Do Hoon · 2017 · Saengmul jeongsin euihag/Saengmul jeongsin uihak
  60. New Insights into Transcranial Magnetic Stimulation (TMS) Treatment of Depression
    Zeljko Milovac, Strahimir Sučić, Tomislav Gajšak, Vjekoslav Aljinović, Sandra Zečević Penić, Ena Ivezić, Igor Filipčić · 2017 · Socijalna psihijatrija
  61. Avaliação da eficácia clínica-cognitiva e segurançaa da estimulação magnética transcraniana com bobina h1 no tratamento de episódios de depressão bipolar
    Martin Luiz Myczkowski · 2018 · Digital Library of Theses and Dissertations (Universidade de São Paulo)
  62. Повторяющаяся транскраниальная магнитная стимуляция в лечении депрессии (обзор литературы)
    Ivan Nikolaevich Bakhmutsky, В.Г. Косенко, L. M. Shulkin, Svetlana Guba, Н. Г. Бахмутский · 2019 · Сибирский вестник психиатрии и наркологии
  63. Precise implantation of super-paramagnetic iron oxide (SPIO) nanoparticles in hippocampus with external rotating magnetic field (RMF) produces rapid antidepressent effects in mice
    Yao Chi, Cai Wenwen, Xia Mengqin, Dai Jingyi, JF Sun Sr. · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
  64. Effects of Non-Invasive Right Prefrontal Stimulation on Cognitive Performance of ADHD Patients
    L. Bokovza, Guy Baz, H. Shalev · 2020 · Journal of Psychiatry and Psychiatric Disorders
  65. The role of the prefrontal cortex in stress and motivation
    Jocelyn Breton · 2020 · eScholarship (California Digital Library)
  66. Investigation of brain networks for personalized rTMS in healthy subjects and patients with major depressive disorder: A translational study
    Aditya Singh · 2021
  67. Pre-TMS Phase of Ongoing EEG Oscillations Modulates Cortical Activity Response at the Prefrontal Cortex
    Aiyush Bansal · 2019 · TSpace (University of Toronto)
  68. Peran Brain Stimulation TMS Pada Prajurit Penderita Depresi Yang Penugasan di Kapal Perang
    I Ketut Tirka Nandaka · 2021 · Hang Tuah Medical journal
  69. Bibliography
    2022 · FOCUS The Journal of Lifelong Learning in Psychiatry
  70. Depressive Störungen
    Gerd Laux · 2016 · Springer eBooks
  71. The Use of Deep Transcranial Magnetic Stimulation in Depression
    Paul Bernard Fitzgerald, Zafiris Jeff Daskalakis · 2022 · Springer eBooks
  72. Estudo randomizado, fase II, duplamente coberto, de estimulação elétrica bilateral subcutânea do nervo trigêmeo para o tratamento de depressão maior unipolar - TREND
    Alessandra Augusta Gorgulho · 2022 · Digital Library of Theses and Dissertations (Universidade de São Paulo)
  73. Editorial
    Irving Michael Reti · 2017 · International Review of Psychiatry
  74. Neuromodulation and Psychiatric Disorders
    Wayne K. Goodman, Mark S. George · 2017 · Oxford University Press eBooks
  75. Modulating microcircuits in depression
    Milaine Roet · 2021
  76. Deep Brain Stimulation for Highly Refractory Depression
    Darin Dean Dougherty, Alik S. Widge, Benjamin David Greenberg · 2018 · Elsevier eBooks
  77. Depressive Disorders
    Anna‐Katharine Brem, Chris Baeken, Martijn Arns, André R. Brunoni, Igor Filipčcić, Ana Ganho-Ávila, Berthold Langguth, Soili Marianne Lehto, Frank Padberg, Emmanuel Poulet et al. · 2020 · Springer eBooks
  78. Stroke
    Nam‐Jong Paik, Won‐Seok Kim · 2016 · Springer eBooks
  79. Transcranial Magnetic Stimulation Tech-nology with Freely Adjustable Pulse Shape and Sequence
    Zhongxi Li, Jinshui Zhang, Angel V. Peterchev, Stefan M. Goetz · 2023
  80. Transcranial Magnetic Stimulation Technology with Freely Adjustable Pulse Shape and Sequence
    Zhongxi Li, Jinshui Zhang, Angel V. Peterchev, Stefan M. Goetz · 2023
  81. Nichtinvasive Hirnstimulationsverfahren
    Lucia Bulubas, Ulrike Kumpf, Malek Bajbouj, Frank Padberg · 2022 · Springer eBooks
  82. Somatic Treatments and Neuromodulation in Psychiatry
    Paul Bernard Fitzgerald, Martijn Arns · 2023 · Springer eBooks
  83. Repetitive transcranial magnetic stimulation implementation within residential substance use disorder treatment centers for patients with comorbid depression
    Mohammad Ali Shenasa, Maryam Soltani, Victor M. Tang, Cory R. Weissman, Lawrence G. Appelbaum, Zafiris Jeff Daskalakis, Dhakshin Ramanathan · 2023 · Advances in Dual Diagnosis
  84. Terapia con estimulación magnética transcraneal repetitiva en trastorno depresivo mayor refractario: eficacia y seguridad. Revisión sistemática
    Juliana Ester Martín-López, Lorena Aguilera-Cobos, Maria Piedad Rosario-Lozano, Juan Antonio Blasco‐Amaro · 2023
  85. Transcranial Magnetic Stimulation Technology with Freely Adjustable Pulse Shape and Sequence
    Zhongxi Li, Jinshui Zhang, Angel V. Peterchev, Stefan M. Goetz · 2023
  86. Whole-Brain Effective Connectivity Analysis Reveals the Existence of Two Mutual Inhibitory Systems and Predicts Treatment Outcomes in Patients with Major Depression
    Baojuan Li A, Jian Liu, Jia Wang, Jiaming Li, Adeel Razi, Kaizhong Zheng, Baoyu Yan, Huaning Wang, Hongbing Lu, Karl John Friston · 2023 · SSRN Electronic Journal
  87. Interventional therapeutics in psychiatry: Beyond psychopharmacology and psychotherapy?
    Frank Padberg, Gerrit Burkhardt · 2024 · Elsevier eBooks
  88. Current Status of Transcranial Magnetic Stimulation for Treating Depression: A Visualization and Bibliometric Analysis (Preprint)
    Anren Zhang, Jia-jia xing, Junyu Wang, Xingyu Liu, Wu Xiang, Jiancheng Liu · 2024
  89. Structural and functional connectivity in patients with major depressive disorder undergoing accelerated intermittent theta burst stimulation
    Tura, Asude · 2024
  90. Lokalisierung und Festlegung des rTMS-Zielortes zur Behandlung von Depressionen
    Paul Bernard Fitzgerald, Zafiris Jeff Daskalakis · 2024 · Springer eBooks
  91. Erhaltungstherapie und Fortsetzung der Behandlung
    Paul Bernard Fitzgerald, Zafiris Jeff Daskalakis · 2024 · Springer eBooks
  92. Verwendung der tiefer reichenden transkraniellen Magnetstimulation bei Depressionen
    Paul Bernard Fitzgerald, Zafiris Jeff Daskalakis · 2024 · Springer eBooks
  93. Neurostimulation Tools and Approaches
    Kristin J. Heaton, Caitlin Ridgewell, Jessica Couse, William H. Neumeier · 2024 · Routledge eBooks
  94. Biomarkers from bench to bedside
    Helena Voetterl · 2024
  95. Somatic Treatments and Neuromodulation in Psychiatry
    Paul Bernard Fitzgerald, Martijn Arns · 2024 · Springer eBooks
  96. Depression and Transcranial Magnetic Stimulation
    Ezgi Inan, Betül Uyar · 2024
  97. Neuromodulation and Psychiatric Disorders
    Andrew H. Smith, Martijn Figee, Helen S. Mayberg · 2025
  98. Rethinking intensity: Repetitive transcranial magnetic stimulation across ethnic populations
    Bella B.B. Zhang, Tim T.Z. Lin, Penny Ping Qin, Minxia Jin, Adam Weili Xia, Rebecca Laidi Kan, Frank Zhu, Georg S. Kranz · 2025 · medRxiv
  99. Stereotactic Radiosurgery for Treatment Resistant Depression: Systematic Review
    J. Vanleuven, Yusuke S. Hori, T. Osama, P. Harary, Austin Lui, Amit R. L. Persad, A. Tayag, S. Emrich, Louisa Ustrzynski, D. Purger et al. · 2025 · World Neurosurgery: X
  100. Early comparative outcomes of electroconvulsive therapy and transcranial magnetic stimulation among depressed patients from a neurotherapeutics registry
    Agustin G. Yip, Marc L. Copersino, Mark A. Halko, Oscar Morales, Paula Bolton, Joshua C. Brown, Kerry James Ressler, Stephen J. Seiner · 2025 · Transcranial magnetic stimulation .