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Morpholino Oligos: Making Sense of Antisense?
Open accessAbstract
Since morpholino oligos were first introduced as a means to inhibit gene function in embryos, in the Spring of 2000, they have been tested in a range of model organisms, including sea urchin, ascidian, zebrafish, frog, chick, and mouse. This review surveys the results of these studies and examines the successes and limitations of the approach for targeting maternal and zygotic gene function. The evidence so far suggests that, with careful controls, morpholinos provide a relatively simple and rapid method to study gene function.
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Metadata
- Authors
- Heasman, J.
- Venue
- Developmental Biology
- Publisher
- Elsevier BV
- Published
- 2002-03
- Volume
- 243
- Issue
- 2
- Pages
- 209-214
- ISSN
- 0012-1606 (ISSN-L)
- OpenAlex
- W2087296674
- Cited by
- 533
- References
- 0
- FWCI
- 21.17
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
