In Situ and in Vitro Study of Colocalization and Segregation of α-Synuclein, Ubiquitin, and Lipids in Lewy Bodies
Gai, W.P., Yuan, H.X., Li, X.Q., Power, J.T.H., Blumbergs, P.C., Jensen, P.H.·2000·Experimental Neurology
Cited by (272)
Items 101–200 of 272
- Copper-Triggered Aggregation of UbiquitinFabio Arnesano, Simone Scintilla, Vincenza Calò, Elena Bonfrate, Chiara Ingrosso, Maurizio Losacco, Teresa Pellegrino, Enrico Rizzarelli, Giovanni Natile · 2009 · PLoS ONE
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- The Role of Oxidative Stress in the Dysregulation of Gene Expression and Protein Metabolism in Neurodegenerative DiseaseJ. Potashkin, G. E. Meredith · 2006 · Antioxidants and Redox Signaling
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- A Stearoyl–Coenzyme A Desaturase Inhibitor Prevents Multiple Parkinson Disease Phenotypes in α ‐Synuclein MiceSilke Nuber, Alice Y. Nam, Molly M. Rajsombath, Haley Cirka, Xiaoping L. Hronowski, Junmin Wang, Kevin J. Hodgetts, Liubov S. Kalinichenko, Christian P. Müller, Vera Lambrecht et al. · 2020 · Annals of Neurology
- Revisiting the specificity and ability of phospho-S129 antibodies to capture alpha-synuclein biochemical and pathological diversityHilal Ahmed Lashuel, Anne‐Laure Mahul‐Mellier, Salvatore Novello, Ramanath Narayana Hegde, Yllza Jasiqi, Melek Firat Altay, Sonia Donzelli, Sean M. DeGuire, Ritwik Burai, Pedro Magalhães et al. · 2022 · npj Parkinson s Disease
- Oxidative stress induces nuclear translocation of C-terminus of α-synuclein in dopaminergic cellsShengli Xu, Ming Zhou, Shun Yu, Yanning Cai, Alex Zhang, Kenji Uéda, Piu Chan · 2006 · Biochemical and Biophysical Research Communications
- Fenpropathrin, a Widely Used Pesticide, Causes Dopaminergic DegenerationJing Xiong, Xiaowei Zhang, Jinsha Huang, Chunnuan Chen, Zhenzhen Chen, Lin Liu, Guoxin Zhang, Jiaolong Yang, Zhentao Zhang, Zhaohui Zhang et al. · 2015 · Molecular Neurobiology
- More than meets the eye in Parkinson’s disease and other synucleinopathies: from proteinopathy to lipidopathyManuel Flores‐León, Tiago F. Outeiro · 2023 · Acta Neuropathologica
- Cholesterol facilitates interactions between α‐synuclein oligomers and charge‐neutral membranesAndreas van Maarschalkerweerd, Valeria Vetri, Bente Vestergaard · 2015 · FEBS Letters
- Potential Role of Epigenetic Mechanism in Manganese Induced NeurotoxicityPrashant Tarale, Tapan Chakrabarti, Saravanadevi Sivanesan, Pravin Krishnarao Naoghare, Amit Bafana, Kannan Krishnamurthi · 2016 · BioMed Research International
- The interaction of α-synuclein and Tau: A molecular conspiracy in neurodegeneration?Yan Xu, Riikka‐Liisa Uronen, Henri J. Huttunen · 2018 · Seminars in Cell and Developmental Biology
- Modeling Parkinson’s disease pathology in human dopaminergic neurons by sequential exposure to α-synuclein fibrils and proinflammatory cytokinesArmin Bayati, Riham Ayoubi, Adriana Aguila, Cornelia E. Zorca, Ghislaine Deyab, Chanshuai Han, Sherilyn Junelle Recinto, Emmanuelle Nguyen, Cecilia Rocha, Gilles Maussion et al. · 2024 · Nature Neuroscience
- Synuclein accumulation is associated with cell‐specific neuronal death after spinal cord injuryDavid J. Busch, Jennifer R. Morgan · 2011 · The Journal of Comparative Neurology
- Novel method for quantitative determination of amyloid fibrils of α-synuclein and amyloid β/A4 protein by using resveratrolJung Sun Ahn, Jung‐Ho Lee, Je-Hoon Kim, Seung R. Paik · 2007 · Analytical Biochemistry
- A critical review of the development and importance of proteinaceous aggregates in animal models of Parkinson's disease: new insights into Lewy body formationGloria E. Meredith, Glenda Margaret Halliday, Susan Totterdell · 2004 · Parkinsonism & Related Disorders
- Dorfin Localizes to the Ubiquitylated Inclusions in Parkinson's Disease, Dementia with Lewy Bodies, Multiple System Atrophy, and Amyotrophic Lateral SclerosisNozomi Hishikawa, Jun-ichi Niwa, Manabu Doyu, Takashi Ito, Shinsuke Ishigaki, Yoshio Hashizume, Gen Sobue · 2003 · American Journal Of Pathology
- Lipid interaction of α‐synuclein during the metal‐catalyzed oxidation in the presence of Cu2+and H2O2Eui‐Nam Lee, Sun‐Young Lee, Daekyun Lee, Jongsun Kim, Seung R. Paik · 2003 · Journal of Neurochemistry
- Development and validation of an expanded antibody toolset that captures alpha-synuclein pathological diversity in Lewy body diseasesMelek Firat Altay, Senthil T. Kumar, Johannes Burtscher, Somanath Jagannath, Catherine Strand, Yasuo Miki, Laura Parkkinen, Janice L. Holton, Hilal Ahmed Lashuel · 2023 · npj Parkinson s Disease
- Increased oxidation of certain glycolysis and energy metabolism enzymes in the frontal cortex in Lewy body diseasesAnna Gómez, Isidró Ferrer · 2008 · Journal of Neuroscience Research
- Lipid Dynamics and Phase Transition within α-Synuclein Amyloid FibrilsCéline Galvagnion, Daniel Topgaard, Katarzyna Makasewicz, Alexander Kai Buell, Sara Snogerup Linse, Emma Sparr, Christopher Martin Dobson · 2019 · The Journal of Physical Chemistry Letters
- Lipid profiling of parkin‐mutant human skin fibroblastsSimona Lobasso, Paola Tanzarella, Daniele Vergara, Michele Maffia, Tiziana Cocco, Angela Corcelli · 2017 · Journal of Cellular Physiology
- Toxic Feedback Loop Involving Iron, Reactive Oxygen Species, α-Synuclein and Neuromelanin in Parkinson’s Disease and Intervention with TurmericZuné Jansen van Rensburg, Shameemah Abrahams, Soraya Bardien, Colin P. Kenyon · 2021 · Molecular Neurobiology
- The interplay between Glucocerebrosidase, α-synuclein and lipids in human models of Parkinson’s diseaseSonia Sanz Muñoz, Daniel Petersen, Frederik Ravnkilde Marlet, Ebru Kücükköse, Céline Galvagnion · 2020 · Biophysical Chemistry
- Alpha-synuclein synaptic pathology and its implications in the development of novel therapeutic approaches to cure Parkinson's diseaseArianna Bellucci, Laura Navarria, Michela Zaltieri, Cristina Missale, PierFranco Spano · 2011 · Brain Research
- Membrane remodeling and mechanics: Experiments and simulations of α-SynucleinAna West, Benjamin E. Brummel, Anthony R. Braun, Elizabeth R. Rhoades, Jonathan N. Sachs · 2016 · Biochimica et Biophysica Acta (BBA) - Biomembranes
- A NAC domain mutation (E83Q) unlocks the pathogenicity of human alpha-synuclein and recapitulates its pathological diversitySenthil T. Kumar, Anne‐Laure Mahul‐Mellier, Ramanath Narayana Hegde, Gwladys Rivière, Rani Moons, Alain Ibáñez de Opakua, Pedro Magalhães, Iman Rostami, Sonia Donzelli, Frank Sobott et al. · 2022 · Science Advances
- Heterogeneity of Nigral and Cortical Lewy Bodies Differentiated by Amplified Triple-Labeling for Alpha-Synuclein, Ubiquitin, and Thiazin RedMasaki Sakamoto, Toshiki Uchihara, Masaharu Hayashi, Ayako Nakamura, Etsuko Kikuchi, Toshio Mizutani, Hidehiro Mizusawa, Shunsaku Hirai · 2002 · Experimental Neurology
- Neuromelanin inhibits enzymatic activity of 26S proteasome in human dopaminergic SH-SY5Y cellsMasayo Shamoto‐Nagai, W. Maruyama, Yukihiro Akao, T. Osawa, Florian Tribl, M. Gerlach, Fabio Andrea Zucca, Luigi Zecca, Peter Franz Riederer, Makoto Naoi · 2004 · Journal of Neural Transmission
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- Sphingolipids in mitochondria—from function to diseaseMaryam Jamil, L. Ashley Cowart · 2023 · Frontiers in Cell and Developmental Biology
- Alpha-synuclein, autophagy-lysosomal pathway, and Lewy bodies: Mutations, propagation, aggregation, and the formation of inclusionsArmin Bayati, Peter Scottt McPherson · 2024 · Journal of Biological Chemistry
- β-Synuclein: An Enigmatic Protein with Diverse FunctionalityJunna Hayashi, J. Carver · 2022 · Biomolecules
- Ageing enhances α-synuclein, ubiquitin and endoplasmic reticular stress protein expression in the nigral neurons of Asian IndiansPhalguni Anand Alladi, Anita Mahadevan, Kandasamy Vijayalakshmi, Uday B. Muthane, S.K. Shankar, T.R. Raju · 2010 · Neurochemistry International
- α-Synuclein, Lrrk2 and Their Interplay In Parkinson‘s DiseaseGuoxiang Liu, Leonardo Aliaga, Huaibin Cai · 2012 · Future Neurology
- Alpha-Synuclein and the Endolysosomal System in Parkinson’s Disease: Guilty by AssociationMaxime Teixeira, Razan Sheta, Walid Idi, Abid Oueslati · 2021 · Biomolecules
- Amyloids of Alpha-Synuclein Affect the Structure and Dynamics of Supported Lipid BilayersAditya Iyer, Nils O. Petersen, Mireille M. A. E. Claessens, Vinod Subramaniam · 2014 · Biophysical Journal
- Ectopic localization of FOXO3a protein in Lewy bodies in Lewy body dementia and Parkinson's diseaseBo Su, Haihua Liu, Xinglong Wang, Shu G. Chen, Sandra L. Siedlak, Eisei Kondo, Raymond Choi, Atsushi Takeda, Rudy J. Castellani, George L. Perry et al. · 2009 · Molecular Neurodegeneration
- Isopentenyl diphosphate isomerase, a cholesterol synthesizing enzyme, is localized in L ewy bodiesKeiko Nakamura, Fumiaki Mori, Kunikazu Tanji, Yasuo Miki, Masahito Yamada, Akiyoshi Kakita, Hitoshi Takahashi, Jun Utsumi, Hidenao Sasaki, Koichi Wakabayashi · 2015 · Neuropathology
- Localization of α-, β-, and γ-synuclein during neuronal development and alterations associated with the neuronal response to axonal traumaMarian C. Quilty · 2003 · Experimental Neurology
- Mulberry fruit ameliorates Parkinson's-disease-related pathology by reducing α-synuclein and ubiquitin levels in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine/probenecid modelPil Sung Gu, Minho Moon, Jin Gyu Choi, Myung Sook Oh · 2016 · The Journal of Nutritional Biochemistry
- Mitochondria and ubiquitin-proteasomal system interplay: Relevance to Parkinson's diseaseAna Filipa Domingues, Daniela M. Arduíno, A. Raquel Esteves, Russell Howard Swerdlow, Catarina Resende Oliveira, Sandra M. Cardoso · 2008 · Free Radical Biology and Medicine
- Regulation of Weibel-Palade Body Exocytosis by α-Synuclein in Endothelial CellsKwang Soo Kim, Jiyoung Park, Ilo Jou, Sang Myun Park · 2010 · Journal of Biological Chemistry
- Neuritic Alterations and Neural System Dysfunction in Alzheimer's Disease and Dementia with Lewy BodiesJochen Klucken, Pamela J. McLean, Estrella Gómez‐Tortosa, Martin Ingelsson, Bradley T. Hyman · 2003 · Neurochemical Research
- Functionally different α-synuclein inclusions yield insight into Parkinson’s disease pathologyC.C. Raiss, Theresa Braun, Irene B. M. Konings, Heinrich Grabmayr, Gerco C. Hassink, Arshdeep Sidhu, Joost le Feber, Andreas R. Bausch, Casper Jansen, Vinod Subramaniam et al. · 2016 · Scientific Reports
- Products of Cu(II)-catalyzed oxidation of the N-terminal fragments of α-synuclein in the presence of hydrogen peroxideTeresa Kowalik‐Jankowska, Anna Rajewska, Elżbieta Jankowska, Kornelia Wiśniewska, Zbigniew Grzonka · 2006 · Journal of Inorganic Biochemistry
- Taking Charge: Metal Ions Accelerate Amyloid Aggregation in Sequence Variants of α-SynucleinEmily J. Byrd, Martin Wilkinson, Sheena E. Radford, Frank Sobott · 2023 · Journal of the American Society for Mass Spectrometry
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