In Situ and in Vitro Study of Colocalization and Segregation of α-Synuclein, Ubiquitin, and Lipids in Lewy Bodies

Gai, W.P., Yuan, H.X., Li, X.Q., Power, J.T.H., Blumbergs, P.C., Jensen, P.H.·2000·Experimental Neurology

Cited by (272)

Items 101–200 of 272

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  9. Fenpropathrin, a Widely Used Pesticide, Causes Dopaminergic Degeneration
    Jing Xiong, Xiaowei Zhang, Jinsha Huang, Chunnuan Chen, Zhenzhen Chen, Lin Liu, Guoxin Zhang, Jiaolong Yang, Zhentao Zhang, Zhaohui Zhang et al. · 2015 · Molecular Neurobiology
  10. More than meets the eye in Parkinson’s disease and other synucleinopathies: from proteinopathy to lipidopathy
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  12. Potential Role of Epigenetic Mechanism in Manganese Induced Neurotoxicity
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  14. Modeling Parkinson’s disease pathology in human dopaminergic neurons by sequential exposure to α-synuclein fibrils and proinflammatory cytokines
    Armin Bayati, Riham Ayoubi, Adriana Aguila, Cornelia E. Zorca, Ghislaine Deyab, Chanshuai Han, Sherilyn Junelle Recinto, Emmanuelle Nguyen, Cecilia Rocha, Gilles Maussion et al. · 2024 · Nature Neuroscience
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  17. A critical review of the development and importance of proteinaceous aggregates in animal models of Parkinson's disease: new insights into Lewy body formation
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  18. Dorfin Localizes to the Ubiquitylated Inclusions in Parkinson's Disease, Dementia with Lewy Bodies, Multiple System Atrophy, and Amyotrophic Lateral Sclerosis
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  19. Lipid interaction of α‐synuclein during the metal‐catalyzed oxidation in the presence of Cu2+and H2O2
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  20. Development and validation of an expanded antibody toolset that captures alpha-synuclein pathological diversity in Lewy body diseases
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  21. Increased oxidation of certain glycolysis and energy metabolism enzymes in the frontal cortex in Lewy body diseases
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  22. Lipid Dynamics and Phase Transition within α-Synuclein Amyloid Fibrils
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  23. Lipid profiling of parkin‐mutant human skin fibroblasts
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  24. Toxic Feedback Loop Involving Iron, Reactive Oxygen Species, α-Synuclein and Neuromelanin in Parkinson’s Disease and Intervention with Turmeric
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  25. The interplay between Glucocerebrosidase, α-synuclein and lipids in human models of Parkinson’s disease
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  26. Alpha-synuclein synaptic pathology and its implications in the development of novel therapeutic approaches to cure Parkinson's disease
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  27. Membrane remodeling and mechanics: Experiments and simulations of α-Synuclein
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  28. A NAC domain mutation (E83Q) unlocks the pathogenicity of human alpha-synuclein and recapitulates its pathological diversity
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  29. Heterogeneity of Nigral and Cortical Lewy Bodies Differentiated by Amplified Triple-Labeling for Alpha-Synuclein, Ubiquitin, and Thiazin Red
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  30. Neuromelanin inhibits enzymatic activity of 26S proteasome in human dopaminergic SH-SY5Y cells
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  32. Sphingolipids in mitochondria—from function to disease
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  33. Alpha-synuclein, autophagy-lysosomal pathway, and Lewy bodies: Mutations, propagation, aggregation, and the formation of inclusions
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  34. β-Synuclein: An Enigmatic Protein with Diverse Functionality
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  36. α-Synuclein, Lrrk2 and Their Interplay In Parkinson‘s Disease
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  37. Alpha-Synuclein and the Endolysosomal System in Parkinson’s Disease: Guilty by Association
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  38. Amyloids of Alpha-Synuclein Affect the Structure and Dynamics of Supported Lipid Bilayers
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  39. Ectopic localization of FOXO3a protein in Lewy bodies in Lewy body dementia and Parkinson's disease
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  40. Isopentenyl diphosphate isomerase, a cholesterol synthesizing enzyme, is localized in L ewy bodies
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  41. Localization of α-, β-, and γ-synuclein during neuronal development and alterations associated with the neuronal response to axonal trauma
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  42. Mulberry fruit ameliorates Parkinson's-disease-related pathology by reducing α-synuclein and ubiquitin levels in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine/probenecid model
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  43. Mitochondria and ubiquitin-proteasomal system interplay: Relevance to Parkinson's disease
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  44. Regulation of Weibel-Palade Body Exocytosis by α-Synuclein in Endothelial Cells
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  45. Neuritic Alterations and Neural System Dysfunction in Alzheimer's Disease and Dementia with Lewy Bodies
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  46. Functionally different α-synuclein inclusions yield insight into Parkinson’s disease pathology
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  48. Taking Charge: Metal Ions Accelerate Amyloid Aggregation in Sequence Variants of α-Synuclein
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  49. Interplay of α-synuclein with Lipid Membranes: Cooperative Adsorption, Membrane Remodeling and Coaggregation
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