Time Course of the Development of Alzheimer-like Pathology in the Doubly Transgenic PS1+APP Mouse

Gordon, Marcia N., Holcomb, Leigh A., Jantzen, Paul T., DiCarlo, Giovanni, Wilcock, Donna, Boyett, Kristal W., Connor, Karen, Melachrino, Jason +2 more·2002·Experimental Neurology
DOI 10.1006/exnr.2001.7754

Cited by (247)

Items 101–200 of 247

  1. Early-Onset and Robust Amyloid Pathology in a New Homozygous Mouse Model of Alzheimer's Disease
    Antje Willuweit, Joachim Velden, Robert Godemann, André Manook, Fritz Jetzek, Hartmut Tintrup, Gunther Kauselmann, Branko Zevnik, Gjermund Henriksen, Alexander E. Drzezga et al. · 2009 · PLoS ONE
  2. Encapsulated native and glucagon-like peptide-1 transfected human mesenchymal stem cells in a transgenic mouse model of Alzheimer's disease
    Petra Margarete Klinge, Kathrin Harmening, Miles C. Miller, Anna Heile, Christine Wallrapp, Peter Geigle, Thomas Brinker · 2011 · Neuroscience Letters
  3. A case for a non‐transgenic animal model of Alzheimer's disease
    Aline Stéphan, A. G. Phillips · 2005 · Genes Brain & Behavior
  4. Quantitative analysis of amyloid plaques in a mouse model of Alzheimer’s disease by phase-contrast X-ray computed tomography
    Kyoko Noda-Saita, Akio Yoneyama, Yoshitsugu Shitaka, Yasuharu Hirai, Kazuhiro Terai, J. Wu, Tetsuro Takeda, Kazuyuki Hyodo, Nobuyuki Osakabe, T. Yamaguchi et al. · 2006 · Neuroscience
  5. Review: Experimental manipulations of microglia in mouse models of <scp>A</scp>lzheimer's pathology: activation reduces amyloid but hastens tau pathology
    Lee, D. C., Rizer, J., Hunt, J. B., Selenica, M.‐L. B., Gordon, M. N., Morgan, D. · 2013 · Neuropathology and Applied Neurobiology
  6. Converging and Differential Brain Phospholipid Dysregulation in the Pathogenesis of Repetitive Mild Traumatic Brain Injury and Alzheimer’s Disease
    Joseph O. Ojo, Moustafa Algamal, Paige Leary, Laila I. Abdullah, Benoit Mouzon, James E. Evans, MICHAEL J. MULLAN, Fiona Crawford · 2019 · Frontiers in Neuroscience
  7. Neurologic and motor dysfunctions in APP transgenic mice
    Robert Lalonde, Ken-ichiro Fukuchi, C. Strazielle · 2012 · Reviews in the Neurosciences
  8. Cerebral Amyloid Angiopathy and Parenchymal Amyloid Deposition in Transgenic Mice Expressing the Danish Mutant Form of Human BRI<sub>2</sub>
    Vidal, Ruben, Barbeito, Ana G., Miravalle, Leticia, Ghetti, Bernardino · 2009 · Brain Pathology
  9. Repair of amyloid β(25–35)-induced memory impairment and synaptic loss by a Kampo formula, Zokumei-to
    Chihiro Tohda, Takayuki Tamura, Katsuko Komatsu · 2003 · Brain Research
  10. Sustained Arginase 1 Expression Modulates Pathological Tau Deposits in a Mouse Model of Tauopathy
    Jerry B. Hunt, Kevin R. Nash, Devon S. Placides, Peter Moran, Maj‐Linda B. Selenica, Firas Abuqalbeen, Kevin Ratnasamy, Nina Slouha, Santiago Rodriguez Ospina, Miloni Savlia et al. · 2015 · Journal of Neuroscience
  11. Learning and Memory Deficits in APP Transgenic Mouse Models of Amyloid Deposition
    David Morgan · 2003 · Neurochemical Research
  12. Proton and Phosphorus Magnetic Resonance Spectroscopy of a Mouse Model of Alzheimer's Disease
    Vladı́mir Mlynárik, Matthias Cacquevel, Lili Sun-Reimer, Sharon Janssens, Cristina Cudalbu, Hongxia Lei, Bernard Laurent Schneider, Patrick Aebischer, Rolf Gruetter A · 2012 · Journal of Alzheimer s Disease
  13. Cortical iron regulation and inflammatory response in Alzheimer's disease and APPSWE/PS1ΔE9 mice: a histological perspective
    Meadowcroft, Mark D., Connor, James R., Yang, Qing X. · 2015 · Frontiers in Neuroscience
  14. The role of microglia in Alzheimer's disease and progress of treatment
    Yi-Huan Guan, Ling-Wei Zhang, Shi-Ya Wang, Yan-Dan Deng, Hong-Su Zhou, Dongran Chen, Lanlan Zhang · 2022 · Ibrain
  15. MER5101, a Novel Aβ1-15:DT Conjugate Vaccine, Generates a Robust Anti-Aβ Antibody Response and Attenuates Aβ Pathology and Cognitive Deficits in APPswe/PS1ΔE9 Transgenic Mice
    Bin Liu, Jeffrey L. Frost, Jing Sun, Hongjun Fu, Stephen Grimes, Peter Blackburn, Cynthia Ann Lemere · 2013 · Journal of Neuroscience
  16. Associative and motor learning in 12-month-old transgenic APP+PS1 mice
    Michael Ewers, David Morgan, Marcia N. Gordon, Diana S. Woodruff‐Pak · 2005 · Neurobiology of Aging
  17. Transition from an M1 to a mixed neuroinflammatory phenotype increases amyloid deposition in APP/PS1 transgenic mice
    Erica M. Weekman, Tiffany L. Sudduth, Erin L. Abner, Gabriel J. Popa, Michael D. Mendenhall, Holly M. Brothers, Kaitlyn J. Braun, Abigail Wolf Greenstein, Donna M. Wilcock · 2014 · Journal of Neuroinflammation
  18. Late onset loss of hippocampal 5-HT and NE is accompanied by increases in BDNF protein expression in mice co-expressing mutant APP and PS1
    Szapacs, Matthew E, Numis, Adam L, Andrews, Anne M · 2004 · Neurobiology of Disease
  19. Intracranial administration of deglycosylated C-terminal-specific anti-Aβ antibody efficiently clears amyloid plaques without activating microglia in amyloid-depositing transgenic mice
    Nikisha Carty, Donna M. Wilcock, Arnon Rosenthal, Jan Grimm, Jaume Pons, Victoria Ronan, Paul E. Gottschall, Marcia N. Gordon, David Morgan · 2006 · Journal of Neuroinflammation
  20. Immunomodulation Targeting Abnormal Protein Conformation Reduces Pathology in a Mouse Model of Alzheimer's Disease
    Fernando Goñi, Frances C. Prelli, Yong Ji, Henrieta Scholtzova, Jing Yang, Yanjie Sun, Feng‐Xia Liang, Regina Kascsak, Richard J. Kascsak, Pankaj D Mehta et al. · 2010 · PLoS ONE
  21. Functional Recovery of Cholinergic Basal Forebrain Neurons under Disease Conditions: Old Problems, New Solutions?
    Wolfgang Härtig, Andreas Bauer, Kurt Brauer, Jens Grosche, Tibor Hortobágyi, Botond Penke, Reinhard Schliebs, Tibor Harkany · 2002 · Reviews in the Neurosciences
  22. Interleukin-13/-4-Induced Oxidative Stress Contributes to Death of Hippocampal Neurons in Aβ 1-42 -Treated Hippocampus In Vivo
    Jin Han Nam, K.W. Park, Eun Su Park, Y.B. Lee, H.G. Lee, Hyung Hwan Baik, Y.-S. Kim, Sungho Maeng, J. Park, Byung Kwan Jin · 2012 · Antioxidants and Redox Signaling
  23. Glial Activation in AβPP/PS1 Mice is Associated with Infiltration of IFNγ-Producing Cells
    Ronan J. Kelly, Aedín M. Minogue, Anthony Lyons, Raasay S. Jones, Tara C. Browne, Derek A. Costello, Stephanie Denieffe, Catherine O'Sullivan, Thomas J. Connor, Marina A. Lynch · 2013 · Journal of Alzheimer s Disease
  24. Modulation of microglial activation state following passive immunization in amyloid depositing transgenic mice
    D MORGAN · 2006 · Neurochemistry International
  25. Acquisition of conditioned taste aversion is impaired in the amyloid precursor protein/presenilin 1 mouse model of Alzheimer’s disease
    Paul J. Pistell, Min Zhu, Donald K. Ingram · 2008 · Neuroscience
  26. Circadian System Functionality, Hippocampal Oxidative Stress, and Spatial Memory in the APPswe/PS1dE9 Transgenic Model of Alzheimer Disease: Effects of Melatonin or Ramelteon
    Beatriz Baño‐Otálora, Natalija Popovic, Juan Gambini, Miroljub Popović, José Viña, Vicent Bonet-Costa, Russel Joseph Reiter, Pedro Javier Camello, Maria Angeles Rol, Juan Antonio Madrid · 2012 · Chronobiology International
  27. Intracranial Injection of AAV Expressing NEP but Not IDE Reduces Amyloid Pathology in APP+PS1 Transgenic Mice
    Nikisha Carty, Kevin R. Nash, Milene Lara Brownlow, Dana Cruite, Donna M. Wilcock, Maj‐Linda B. Selenica, Daniel C. Lee, Marcia N. Gordon, David Morgan · 2013 · PLoS ONE
  28. Chronic PERK induction promotes Alzheimer-like neuropathology in Down syndrome: Insights for therapeutic intervention
    Chiara Lanzillotta, Ilaria Zuliani, Antonella Tramutola, Eugenio Barone, Carla Blarzino, Valentina Folgiero, Matteo Caforio, Diletta Valentini, Alberto Villani, Franco Locatelli et al. · 2020 · Progress in Neurobiology
  29. Immunomodulation targeting of both Aβ and tau pathological conformers ameliorates Alzheimer’s disease pathology in TgSwDI and 3xTg mouse models
    Goñi, Fernando, Herline, Krystal, Peyser, Daniel, Wong, Kinlung, Ji, Yong, Sun, Yanjie, Mehta, Pankaj, Wisniewski, Thomas · 2013 · Journal of Neuroinflammation
  30. Metabolic changes over the course of aging in a mouse model of tau deposition
    Aurélie Joly‐Amado, Karisa S. Serraneau, Milene Lara Brownlow, Caralina Marín de Evsikova, John Roger Speakman, Marcia N. Gordon, David Morgan · 2016 · Neurobiology of Aging
  31. PSAPP mice exhibit regionally selective reductions in gliosis and plaque deposition in response to S100B ablation
    Emily A. Roltsch, Leigh A. Holcomb, Keith A Young, Alexander Marks, Danna B. Zimmer · 2010 · Journal of Neuroinflammation
  32. Toward Development of Neuron Specific Transduction After Systemic Delivery of Viral Vectors
    Dylan J. Finneran, Ikenna P. Njoku, Diego Flores-Pazarin, Meghana Ranabothu, Kevin R. Nash, David Morgan, Marcia N. Gordon · 2021 · Frontiers in Neurology
  33. Brainstem Alzheimer's-like pathology in the triple transgenic mouse model of Alzheimer's disease
    Cassia Overk, Christy M. Kelley, Elliott Jay Mufson · 2009 · Neurobiology of Disease
  34. The Novel DA–CH3 Dual Incretin Restores Endoplasmic Reticulum Stress and Autophagy Impairments to Attenuate Alzheimer-Like Pathology and Cognitive Decrements in the APP SWE /PS1 ΔE9 Mouse Model
    Theodora Panagaki, Simon Gengler, Christian Hölscher · 2018 · Journal of Alzheimer s Disease
  35. Epitope analysis following active immunization with tau proteins reveals immunogens implicated in tau pathogenesis
    Selenica, Maj-Linda B, Davtyan, Hayk, Housley, Steven B, Blair, Laura J, Gillies, Anne, Nordhues, Bryce A, Zhang, Bo, Liu, Joseph, Gestwicki, Jason E, Lee, Daniel C et al. · 2014 · Journal of Neuroinflammation
  36. Alzheimer’s disease pathological lesions activate the spleen tyrosine kinase
    Jonas Elias Schweig, Hailan Yao, David Beaulieu‐Abdelahad, Ghania Ait‐Ghezala, Benoit Mouzon, Fiona Crawford, MICHAEL J. MULLAN, Daniel Paris · 2017 · Acta Neuropathologica Communications
  37. Vaccination with a non-human random sequence amyloid oligomer mimic results in improved cognitive function and reduced plaque deposition and micro hemorrhage in Tg2576 mice
    Suhail Rasool, Ricardo Albay, Hilda Martínez‐Coria, Leonid Breydo, Jessica Wu, Saskia C. F. Milton, Sunit Misra, Andy T Tran, Anna Pensalfini, Frank M. LaFerla et al. · 2012 · Molecular Neurodegeneration
  38. The Ca2+ sensor S100A1 modulates neuroinflammation, histopathology and Akt activity in the PSAPP Alzheimer's disease mouse model
    Lauriaselle Afanador, Emily A. Roltsch, Leigh A. Holcomb, Kerry S. Campbell, David A. Keeling, Yan Zhang, Danna B. Zimmer · 2014 · Cell Calcium
  39. Alzheimer's disease-like neuropathology of gene-targeted APP-SLxPS1mut mice expressing the amyloid precursor protein at endogenous levels
    Köhler, Christoph, Ebert, Ulrich, Baumann, Karlheinz, Schröder, Hannsjörg · 2005 · Neurobiology of Disease
  40. Differences in Synaptic Dysfunction Between rTg4510 and APP/PS1 Mouse Models of Alzheimer’s Disease
    Simon Gelman, Jonathan D. Palma, Geoffrey C. Tombaugh, Afshin Ghavami · 2017 · Journal of Alzheimer s Disease
  41. CNS-Wide over Expression of Fractalkine Improves Cognitive Functioning in a Tauopathy Model
    Dylan J. Finneran, David Morgan, Marcia N. Gordon, Kevin R. Nash · 2018 · Journal of Neuroimmune Pharmacology
  42. Behavioral consequences of ovarian atrophy and estrogen replacement in the APPswe mouse
    Mari S. Golub, Stacey L. Germann, Mary Mercer, Marcia N. Gordon, David Morgan, Loretta P. Mayer, Patricia B. Hoyer · 2007 · Neurobiology of Aging
  43. Tissue-Specific Metabolomics Analysis Identifies the Liver as a Major Organ of Metabolic Disorders in Amyloid Precursor Protein/Presenilin 1 Mice of Alzheimer’s Disease
    Hong Xing Zheng, Aimin Cai, Qi Shu, Yan Niu, Pengtao Xu, Chen Li, Li Lin, Hongchang Gao · 2018 · Journal of Proteome Research
  44. Sensorineural hearing loss may lead to dementia-related pathological changes in hippocampal neurons
    Yilin Shen, Haixia Hu, Fan Cui, Quan Wang, Tianyuan Zou, Bin Ye, Mingliang Xiang · 2021 · Neurobiology of Disease
  45. Suppression of Amyloid Deposition Leads to Long-Term Reductions in Alzheimer's Pathologies in Tg2576 Mice
    Rachel Karlnoski, Arnon Rosenthal, Dione T. Kobayashi, Jaume Pons, Jennifer Alamed, Mary Mercer, Qingyou Li, Marcia N. Gordon, Paul E. Gottschall, David Morgan · 2009 · Journal of Neuroscience
  46. Vitamin C deficiency increases basal exploratory activity but decreases scopolamine-induced activity in APP/PSEN1 transgenic mice
    Fiona Edith Harrison, James Michael May, Michael P. McDonald · 2009 · Pharmacology Biochemistry and Behavior
  47. Increased Fibrillar β-Amyloid in Response to Human C1q Injections into Hippocampus and Cortex of APP+PS1 Transgenic Mice
    Kristal W. Boyett, Giovanni DiCarlo, Paul T. Jantzen, Jennifer Jackson, Charlotte O’Leary, Donna M. Wilcock, David Morgan, Marcia N. Gordon · 2003 · Neurochemical Research
  48. Up-regulation of Bcl-2 in APP transgenic mice is associated with neuroprotection
    Rachel Karlnoski, Donna M. Wilcock, Chad A. Dickey, Victoria Ronan, Marcia N. Gordon, Wenru Zhang, David Morgan, Giulio Taglialatela · 2006 · Neurobiology of Disease
  49. Effects of sub-chronic donepezil on brain Abeta and cognition in a mouse model of Alzheimer’s disease
    Amy E. Easton, Sethu Sankaranarayanan, An Tanghe, Dick Terwel, Alan Lin, Nina Hoque, Clotilde Bourin, Huidong Gu, Michael K. Ahlijanian, Linda J. Bristow · 2013 · Psychopharmacology
  50. Amyloid precursor protein in pancreatic islets
    Joshua A. Kulas, Kendra L. Puig, Colin Kelly Combs · 2017 · Journal of Endocrinology
  51. What Can Rodent Models Tell Us About Cognitive Decline in Alzheimer's Disease?
    Sabrina Davis, Serge Laroche · 2003 · Molecular Neurobiology
  52. Inhibition of casein kinase 1δ/εimproves cognitive-affective behavior and reduces amyloid load in the APP-PS1 mouse model of Alzheimer’s disease
    Saranya S. Sundaram, S Nagaraj, Heather L. Mahoney, Alexandra Portugues, W. Li, K. Millsaps, J. Faulkner, Amara Yunus, Camden I Burns, C. Bloom et al. · 2019 · Scientific Reports
  53. Emerging Promise of Immunotherapy for Alzheimer’s Disease: A New Hope for the Development of Alzheimer’s Vaccine
    Md. Tanvir Kabir, Md. Sahab Uddin, Bijo Mathew, Pankoj Kumar Das, Asma Perveen, Ghulam Md Ashraf · 2020 · Current Topics in Medicinal Chemistry
  54. Activation of nicotinic α7 acetylcholine receptor enhances long term potentation in wild type mice but not in APPswe/PS1ΔE9 mice
    Andreas Søderman, Jens Damsgaard Mikkelsen, Mark J. West, Ditte Z. Christensen, Morten S. Jensen · 2010 · Neuroscience Letters
  55. Active immunization with tau epitope in a mouse model of tauopathy induced strong antibody response together with improvement in short memory and pSer396-tau pathology
    Aurélie Joly‐Amado, Hayk Davtyan, Karisa S. Serraneau, P. Jules, Ashley Zitnyar, Elliot Pressman, Karen Zagorski, Tatevik Antonyan, Armine Hovakimyan, Ha‐Na Paek et al. · 2019 · Neurobiology of Disease
  56. The Rhythmicity of Clock Genes is Disrupted in the Choroid Plexus of the APP/PS1 Mouse Model of Alzheimer’s Disease
    André Furtado, Rosario Astaburuaga-García, Ana Raquel Costa, Ana Catarina Duarte, Isabel Gonçalves, José Cipolla‐Neto, Manuel Carlos Lemos, Eva Carro, Angela Relógio, Cecília R.A. Santos et al. · 2020 · Journal of Alzheimer s Disease
  57. Low-Dose Radiation Therapy Reduces Amyloid Load in Young 3xTg-AD Mice
    Kelly Ceyzériat, Benjamin B. Tournier, P. Millet, Giovanna Dipasquale, Nikolaos Koutsouvelis, Giovanni Battista Frisoni, Valentina Garibotto, Thomas Zilli · 2022 · Journal of Alzheimer s Disease
  58. Animal models of Alzheimer’s disease: preclinical insights and challenges
    Qingqing Xu, Wen Yang, Mei Zhong, Zhi‐Xiu Lin, Nora E. Gray, Yan‐Fang Xian · 2023 · Acta Materia Medica
  59. Vaccine Development to Treat Alzheimer’s Disease Neuropathology in APP/PS1 Transgenic Mice
    Iván Carrera, Ignacio Etcheverrı́a, L. Fernández‐Novoa, Valter Lombardi, Ramón Cacabelos, Carmen Vigo · 2012 · International Journal of Alzheimer s Disease
  60. Neuro-Immuno-Gene- and Genome-Editing-Therapy for Alzheimer’s Disease: Are We There Yet?
    Sudhanshu P. Raikwar, Ramasamy Thangavel, Iuliia Dubova, Mohammad Ejaz Ahmed, Govindhasamy Pushpavathi Selvakumar, Duraisamy Kempuraj, Smita A. Zaheer, Shankar S. Iyer, Asgar Zaheer · 2018 · Journal of Alzheimer s Disease
  61. Analysis of neurological disease in four dimensions: insight from ALS-PDC epidemiology and animal models
    C. Shaw, Jason M. B. Wilson · 2003 · Neuroscience & Biobehavioral Reviews
  62. Magnetization transfer contrast imaging reveals amyloid pathology in Alzheimer's disease transgenic mice
    Christian Bigot, Greetje Vanhoutte, Marleen Verhoye, Annemie Van der Linden · 2013 · NeuroImage
  63. Arginase 1 Insufficiency Precipitates Amyloid-β Deposition and Hastens Behavioral Impairment in a Mouse Model of Amyloidosis
    Ma, Chao, Hunt, Jerry B., Selenica, Maj-Linda B., Sanneh, Awa, Sandusky-Beltran, Leslie A., Watler, Mallory, Daas, Rana, Kovalenko, Andrii, Liang, Huimin, Placides, Devon et al. · 2021 · Frontiers in Immunology
  64. Interactions of Npc1 and amyloid accumulation/deposition in the APP/PS1 mouse model of Alzheimer’s
    Ivan A. Borbon, Robert P. Erickson · 2010 · Journal of Applied Genetics
  65. The nicotinic α7 acetylcholine receptor agonist ssr180711 is unable to activate limbic neurons in mice overexpressing human amyloid-β1–42
    Andreas Søderman, Morten Skøtt Thomsen, Henrik H. Hansen, Elsebet Østergaard Nielsen, Morten S. Jensen, Mark J. West, Jens Damsgaard Mikkelsen · 2008 · Brain Research
  66. High throughput object-based image analysis of β-amyloid plaques in human and transgenic mouse brain
    Harry Samaroo, Alan Opsahl, Jan Schreiber, Sharon O'Neill, Michael Marconi, Jessie Qian, Santos Carvajal‐Gonzalez, Barbara A. Tate, Anthony J. Milici, Kelly R. Bales et al. · 2011 · Journal of Neuroscience Methods
  67. Amyloid, memory and neurogenesis
    David Morgan · 2007 · Experimental Neurology
  68. Gene Expression Profiling in the APP/PS1KI Mouse Model of Familial Alzheimer’s Disease
    Robert Weißmann, Melanie Hüttenrauch, Tim Kacprowski, Yvonne Bouter, Laurent Pradier, Thomas A. Bayer, Andreas Walter Kuss, Oliver Wirths · 2016 · Journal of Alzheimer s Disease
  69. Deglycosylated Anti-Aβ Antibody Dose–Response Effects on Pathology and Memory in APP Transgenic Mice
    Rachel Karlnoski, Arnon Rosenthal, Jennifer Alamed, Victoria Ronan, Marcia N. Gordon, Paul E. Gottschall, Jan Grimm, Jaume Pons, David Morgan · 2008 · Journal of Neuroimmune Pharmacology
  70. Early monocyte modulation by the non-erythropoietic peptide ARA 290 decelerates AD-like pathology progression
    Mohammed Al‐Onaizi, Peter Thériault, Sarah Lecordier, Paul Préfontaine, Serge Rivest, Ayman ElAli · 2021 · Brain Behavior and Immunity
  71. Development and Evaluation of Iodinated Tracers Targeting Amyloid Plaques for SPECT Imaging
    Mei‐Ping Kung, Zhi‐Ping Zhuang, Cathy Hou, Hank F. Kung · 2004 · Journal of Molecular Neuroscience
  72. Recovery and aging of serotonergic fibers after single and intermittent MDMA treatment in dark agouti rat
    Csaba Ádori, Rómeó D. Andó, Mária Szekeres, Lise Gutknecht, Gábor Géza Kovács, László Hunyady, Klaus‐Peter Lesch, György Bagdy · 2011 · The Journal of Comparative Neurology
  73. Cell Therapy: A Safe and Efficacious Therapeutic Treatment for Alzheimer’s Disease in APP+PS1 Mice
    Neel R. Nabar, Fang Yuan, Xiaoyang Lin, Li Wang, Ge Bai, Jonathan J. Mayl, Yaqiong Li, Shu‐Feng Zhou, Jinhuan Wang, Jianfeng Cai et al. · 2012 · PLoS ONE
  74. Inhibition of the mitochondrial pyruvate carrier in astrocytes reduces amyloid and tau accumulation in the 3xTgAD mouse model of Alzheimer's disease
    Ceyzériat, Kelly, Badina, Aurélien M., Petrelli, Francesco, Montessuit, Sylvie, Nicolaides, Alekos, Millet, Philippe, Savioz, Armand, Martinou, Jean-Claude, Tournier, Benjamin B. · 2024 · Neurobiology of Disease
  75. Immunocytochemical Characterization of Alzheimer Disease Hallmarks in APP/PS1 Transgenic Mice Treated with a New Anti-Amyloid-βVaccine
    Iván Carrera, Ignacio Etcheverrı́a, Yi Li, L. Fernández‐Novoa, Valter Lombardi, Carmen Vigo, Hector H. Palacios, Valery V. Benberin, Ramón Cacabelos, Gjumrakch Aliev · 2013 · BioMed Research International
  76. Effects of Repetitive Exposure to Anesthetics and Analgesics in the Tg2576 Mouse Alzheimer’s Model
    Carolina Quiroga, Rafael E Chaparro, Rachel Karlnoski, Diana M. Erasso, Marcia N. Gordon, David Morgan, Gerardo Bosco, Alessandro Rubini, Andrea Parmagnani, Antonio Paoli et al. · 2014 · Neurotoxicity Research
  77. Circulating Plasma microRNAs are Altered with Amyloidosis in a Mouse Model of Alzheimer’s Disease
    Margaret M. Ryan, Diane Guévremont, Bruce G. Mockett, Wickliffe C. Abraham, Joanna M. Williams · 2018 · Journal of Alzheimer s Disease
  78. Virus-like Peptide Vaccines Against Aß N-terminal or C-Terminal Domains Reduce Amyloid Deposition in APP Transgenic Mice without Addition of Adjuvant
    Qing-you Li, Marcia N. Gordon, Bryce Chackerian, Jennifer Alamed, Kenneth E. Ugen, David Morgan · 2010 · Journal of Neuroimmune Pharmacology
  79. Aβ Infusion and Related Models of Alzheimer Dementia
    Patricia A. Lawlor, Deborah Young · 2010 · Neuromethods
  80. Yeast-Based Aβ1-15 Vaccine Elicits Strong Immunogenicity and Attenuates Neuropathology and Cognitive Deficits in Alzheimer’s Disease Transgenic Mice
    Dong‐qun Liu, Shuai Lü, Lun Zhang, Yaru Huang, Mei Ji, Xiaoying Sun, Xiaoge Liu, Rui‐tian Liu · 2020 · Vaccines
  81. Critical thinking of Alzheimer’s transgenic mouse model: current research and future perspective
    Xinyue Li, Meina Quan, Yiping Wei, Wei Wang, Lingzhi Xu, Qi Wang, Jianping Jia · 2023 · Science China Life Sciences
  82. Chronological Age Impacts Immunotherapy and Monocyte Uptake Independent of Amyloid Load
    Qingyou Li, Lori A. Lebson, Daniel C. Lee, Kevin R. Nash, Jan Grimm, Arnon Rosenthal, Maj‐Linda B. Selenica, David Morgan, Marcia N. Gordon · 2011 · Journal of Neuroimmune Pharmacology
  83. Detection of Alzheimer’s disease amyloid-beta plaque deposition by deep brain impedance profiling
    Amélie Béduer, Pierre Joris, Sébastien Mosser, Patrick C. Fraering, Philippe Renaud · 2015 · Journal of Neural Engineering
  84. Unbiased Proteomic Approach Identifies Pathobiological Profiles in the Brains of Preclinical Models of Repetitive Mild Traumatic Brain Injury, Tauopathy, and Amyloidosis
    Joseph O. Ojo, Gogce C. Crynen, Moustafa Algamal, Prashanti Vallabhaneni, Paige Leary, Benoit Mouzon, Jon M. Reed, MICHAEL J. MULLAN, Fiona Crawford · 2020 · ASN NEURO
  85. Circadian rhythmicity of amyloid‐beta‐related molecules is disrupted in the choroid plexus of a female Alzheimer's disease mouse model
    André Furtado, André J. Esgalhado, Ana Catarina Duarte, Ana Raquel Costa, Ana Raquel Costa‐Brito, Eva Carro, Hiroshi Ishikawa, Horst Schroten, Christian Schwerk, Isabel Gonçalves et al. · 2022 · Journal of Neuroscience Research
  86. Unbiased Proteomic Approach Identifies Unique and Coincidental Plasma Biomarkers in Repetitive mTBI and AD Pathogenesis
    Joseph O. Ojo, Gogce C. Crynen, Jon M. Reed, Rosa Ajoy, Prashanthi Vallabhaneni, Moustafa Algamal, Paige Leary, Naomi G. Rafi, Benoit Mouzon, MICHAEL J. MULLAN et al. · 2018 · Frontiers in Aging Neuroscience
  87. Procyanidins Extracted from the Lotus Seedpod Ameliorate Cognitive Impairment through CREB-BDNF Pathway Mediated LTP in APP/PS1 Transgenic Mice
    Ziping Wang, Xiaolong Li, Xiaotong Ren, Siqi Zhao, Wenwen Chen, Cheng Fan, Yangliu Xu, Xuejiao Pi, Yidan Zhang, Ting Wang et al. · 2023 · Current Pharmaceutical Biotechnology
  88. TSPO contributes to neuropathology and cognitive deficits in Alzheimer’s disease
    Kelly Ceyzériat, Aurélien M. Badina, Laurene Abjean, Léa Meyer, Farha Bouteldja, Marta Bałkota, Quentin Amossé, Oriane Prudhomme, Ryan J. Middleton, Guo-Jun Liu et al. · 2025 · Journal of Neuroinflammation
  89. Activation of the Amyloid Cascade by Intracerebroventricular Injection of the Protease Inhibitor Phosphoramidon
    Yotam Nisemblat, Haim Belinson, Iftach Dolev, Daniel M. Michaelson · 2008 · Neurodegenerative Diseases
  90. Characterization of an ‘Amyloid Only’ Transgenic (B6C3-Tg(APPswe,PSEN1dE9)85Dbo/Mmjax) Mouse Model of Alzheimer's Disease
    G.S. Finnie, Ronny Kent Gunnarsson, Jim Manavis, Peter Charles Blumbergs, K.A. Mander, Stephen R. Edwards, Cameron J. van den Heuvel, John W Finnie · 2017 · Journal of Comparative Pathology
  91. Mechanisms of Microglial Activation by Amyloid Precursor Protein and its Proteolytic Fragments
    Susan A. Austin, Colin Kelly Combs · 2007 · Springer eBooks
  92. Neural atrophy produced by AAV tau injections into hippocampus and anterior cortex of middle-aged mice
    Amber M. Tetlow, Brianna M. Jackman, Mohammed M. Alhadidy, Patricia C. Muskus, David Morgan, Marcia N. Gordon · 2022 · Neurobiology of Aging
  93. Antibody therapy for Alzheimer’s disease
    David Morgan · 2003 · Expert Review of Vaccines
  94. Adolescent exposure to MDMA induces dopaminergic toxicity in substantia nigra and potentiates the amyloid plaque deposition in the striatum of APPswe/PS1dE9 mice
    Sònia Abad, Carla Ramon‐Duaso, David Pubill, Jorge Camarasa, Antoni Camins, Elena Escubedo · 2016 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  95. Long-term oral administration of curcumin is effective in preventing short-term memory deterioration and prolonging lifespan in a mouse model of Alzheimer’s disease
    Hiroko Maruyama, Takahito Ooizumi, Fumitaka Kawakami, Thet‐Thet Lwin, Hisanao Akita, Takuya Kunii, Ryota Shirai, Tohoru Takeda · 2023 · Oriental Pharmacy and Experimental Medicine
  96. Overexpression of human wtTDP-43 causes impairment in hippocampal plasticity and behavioral deficits in CAMKII-tTa transgenic mouse model
    Zainuddin Quadri, Nicholas James Johnson, Frank Zamudio, Abraian Miller, Melinda M. Peters, Shayna Smeltzer, Jerry B. Hunt, Steven B. Housley, Breanna Brown, Susan D. Kraner et al. · 2019 · Molecular and Cellular Neuroscience
  97. Induction of tauopathy in a mouse model of amyloidosis using intravenous administration of adeno‐associated virus vectors expressing human P301L tau
    Dylan J. Finneran, Taylor Desjarlais, Alayna Henry, Brianna M. Jackman, Marcia N. Gordon, David Morgan · 2024 · Alzheimer s & Dementia Translational Research & Clinical Interventions
  98. Transcriptional Analysis in the Brain: Trophin-Induced Hippocampal Synaptic Plasticity
    Janet Alder, Smita Thakker‐Varia, Ira B. Black · 2002 · Neurochemical Research
  99. Cholinergic Neurotransmission, Amyloid-β Peptide and the Pathogenesis of Alzheimer's Disease
    Li Liu · 2003
  100. Citrullination of TDP-43 is a key post-translation modification associated with structural and functional changes and progressive pathology in TDP-43 mouse models and human proteinopathies
    Christopher Saunders, Patricia Rocha-Rangel, Rohan Desai, Zainuddin Quadri, Haiying Lui, Jerry B. Hunt, Huimin Liang, Colin B. Rogers, Kevin R. Nash, Phoebe S. Tsoi et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)