Assignment of the Endothelial-Specific Protein Receptor Tyrosine Kinase Gene (TEK) to Human Chromosome 9p21
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The activity of Ang-1 can enhance VEGF receptor function for vascular development, remodeling, stabilization, and final maturation.
“The activity of Ang-1 can enhance VEGF receptor function for vascular development, remodeling, stabilization, and final maturation (85)(86)(87)”
From Adipose tissue remodeling and obesity (2011) · cites this paper as [85]
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“Two unrelated VMCM families previously were linked to an 8 cM region of 9p21 (4,8) containing the receptor tyrosine kinase TIE2 (TEK )g ene (7, 9 ), a member of a novel family of receptor tyrosine kinases expressed almost exclusively on endothelial cells (10‐15).”
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Jurisic, G., & Detmar, M. J. (2008) · Cell and Tissue Research · doi:10.1007/s00441-008-0644-2 · Cited by 118 · see citing works
Gene Expression in the Normal Adult Human Kidney Assessed by Complementary DNA Microarray
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“Vol. 15, February 2004 651 actinin alpha 4, Kaplan et al., 2000; GLEPP1, Thomas et al., 1994; tight junction protein ZO-1, Kurihara et al., 1992; Schnabel et al., 1990); glomerular endothelium (TEK [tyrosine kinase], Dumont et al., 1994; and EDG1, Liu et al., 2000); and mesangial cells (endoglin, Rodriguez-Barbero et…”
BackgroundCommonly occurring loss and mutation of the MXI1 gene in prostate cancer
Prochownik, E. V., Grove, L. E., Deubler, D. A., Zhu, X. L., Stephenson, R. A., Rohr, L. R., Yin, X., & Brothman, A. R. (1998) · Genes Chromosomes and Cancer · doi:10.1002/(sici)1098-2264(199808)22:4 · Cited by 84 · see citing works
Angioarrestin: A unique angiopoietin-related protein with anti-angiogenic properties
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“…cell (Huang et al., 1999; reviewed by Schatteman et al., 2006), and Tie proteins are expressed in the endothelial cells of developing blood vessels (Dumont et al., 1992, 1994a,b; Korhonen et al., 1992) and in hematopoietic cells of the fetal liver (Hsu et al., 2000) and bone marrow (Batard et al.,…”
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“It controls endothelial cell proliferation, differentiation, and adhesion between pericytes and endothelial cells [53].”
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Disorders of the Venous System
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Virological and clinical characteristics of human herpesvirus 6.
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“A new candidate gene encoding the endothelial specific receptor tyrosine kinase (TIE2/TEK) had been localized to 9p21.(3) Using 2 melanoma cell lines with proven homozygous deletions in the 9p region, we discovered that the TIE2 gene must be located in between the interferon (IFN) gene cluster and marker D9S3.”
Disorders of the Venous System
Brouillard, P., Limaye, N., Boon, L. M., & Vikkula, M. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-812532-8.00009-4
Dumont, D. (1995) · Elsevier eBooks · doi:10.1016/b978-012324719-3/50177-1
Self-citation
- Authors
- Dumont, D. J., Anderson, L., Breitman, M. L., & Duncan, A. M. V.
- Affiliations
- Mount Sinai Hospital (CA)
- ORCID
- Dumont, Daniel J.
- Venue
- Genomics
- Publisher
- Elsevier BV
- Published
- 1994-09
- Volume
- 23
- Issue
- 2
- Pages
- 512-513
- ISSN
- 0888-7543 (ISSN-L)
- OpenAlex
- W2050343064
- Cited by
- 22
- References
- 0
- Citations by year
- 2022: 1 · 2020: 1 · 2019: 1 · 2015: 3 · 2013: 1
- FWCI
- 0.84
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Genomics (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Vascular Malformations and Hemangiomas
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Angiogenesis and VEGF in Cancer
- Health Sciences › Medicine › Surgery › Vascular anomalies and interventions
- Keywords
- gene mapping, chromosome 9p21, receptor tyrosine kinase, endothelial cells, venous malformation, glomuvenous malformation, blue rubber bleb nevus syndrome, vascular smooth muscle cell differentiation, anticancer drug repurposing
- MeSH terms
- Chromosome Mapping, Chromosomes, Human, Pair 9, Endothelium, Humans, Neoplasms, Oncogenes, Protein-Tyrosine Kinases, Proteins, In Situ Hybridization
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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