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Issues in the Pharmacokinetics of Trichloroethylene and Its Metabolites

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Cellular pharmacodynamics of immunosuppressive drugs for individualized medicine

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Editor’s Highlight: Comparative Dose-Response Analysis of Liver and Kidney Transcriptomic Effects of Trichloroethylene and Tetrachloroethylene in B6C3F1 Mouse

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Incorporating human interindividual biotransformation variance in health risk assessment

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Correlating in vitro data to in vivo findings for risk assessment.

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Application of in vitro biotransformation data and pharmacokinetic modeling to risk assessment

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The effect of experimental low zearalenone intoxication on ovarian follicles in pre-pubertal bitches

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More methemoglobin is produced by benzocaine treatment than lidocaine treatment in human in vitro systems

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In vitro Phase I- and Phase II-Drug Metabolism in The Liver of Juvenile and Adult Göttingen Minipigs

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Induction or inhibition of cytochrome P450 2E1 modifies the acute toxicity of acrylonitrile in rats: biochemical evidence

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Incorporation of Pharmacokinetic and Pharmacodynamic Data into Risk Assessments

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Age-related Differences in CYP3A Abundance and Activity in the Liver of the Göttingen Minipig

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Estimation of interindividual variation in oxidative metabolism of dichloromethane in human volunteers

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Assembling the P450 puzzle: on the sources of nonadditivity in drug metabolism

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The Oncopig Cancer Model as a Complementary Tool for Phenotypic Drug Discovery

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Genetic polymorphism and mRNA levels of cytochrome P450IIE1 and glutathione S-transferase P1 in patients with alcoholic liver disease in different nationalities.

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An in vitro system for studying potential biological mechanisms of human sex differences in susceptibility to acute liver injury

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Biotransformation of phytoestrogens from soy in enzymatically characterized liver microsomes and primary hepatocytes of Atlantic salmon

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Mode of Action Considerations in the Quantitative Assessment of Tumour Responses in the Liver

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Public Health Goal for TETRACHLOROETHYLENE In Drinking Water

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Evaluation of HepaRG cells for the assessment of indirect drug-induced hepatotoxicity using INH as a model substance

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PBPK Modeling: A Primer

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Development and validation of an enzyme-linked immunosorbent assay for the quantification of cytochrome 3A4 in human liver microsomes

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Microsomal Cytochrome P450 Levels and Activities of Isolated Rat Livers Perfused with Albumin

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Quantitative Evaluation of Cytochrome P450 3A4 Inhibition and Hepatotoxicity in HepaRG 3-D Spheroids

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