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Cited by 10Sexual Differentiation and DisordersAdrenal Hormones and DisordersHormonal Regulation and Hypertension

Medical treatment of classic and nonclassic congenital adrenal hyperplasia

Speiser, Phyllis W.·2011·Advances in experimental medicine and biology
DOI 10.1007/978-1-4419-8002-1_9
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Crossref · 10.1007/978-1-4419-8002-1_9

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23 of 23 references verified0 citation errors · 0 not checkable

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  • In NC CAH, the estimated residual enzymatic activity of CYP21A2 is about 20-50% based on in vitro or in silico studies, resulting in a generally mild but highly variable phenotype.

    “In NC CAH the estimated residual enzymatic activity of CYP21A2 is about 20 -50% based on in vitro or in silico studies, resulting in a generally mild but highly variable phenotype (212,217,416).”

    From Congenital Adrenal Hyperplasia—Current Insights in Pathophysiology, Diagnostics, and Management (2022) · cites this paper as [416]

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Authors
Speiser, P. W.
Affiliations
Cohen Children's Medical Center (US)
Corresponding author
Speiser, Phyllis W.
ORCID
Speiser, Phyllis W.
Venue
Advances in experimental medicine and biology
Publisher
Springer New York
Published
2011
Volume
707
Pages
41-45
ISSN
0065-2598 (ISSN-L)
DOI
10.1007/978-1-4419-8002-1_9
OpenAlex
W186451216
Cited by
10
References
23
Citations by year
2023: 1 · 2022: 1 · 2021: 1 · 2020: 1 · 2018: 2 · 2017: 2 · 2016: 1 · 2012: 1
FWCI
0.42
Type
book chapter
Language
en
Open access
closed
Licence
Locations
  • Advances in experimental medicine and biology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Sexual Differentiation and Disorders
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adrenal Hormones and Disorders
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Hormonal Regulation and Hypertension
Keywords
congenital adrenal hyperplasia, medical therapy, glucocorticoid replacement therapy, mineralocorticoid replacement, aldosterone deficiency, hyperandrogenism, adrenal crisis, masculinization, fertility, growth and development
MeSH terms
Adrenal Hyperplasia, Congenital, Dose-Response Relationship, Drug, Glucocorticoids, Humans

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