The DOI matches its Crossref record; 108 of the 108 references it cites were found in a registry or an index.
Neisseria meningitidis: Biology, Microbiology, and Epidemiology
Open accessAbstract
Neisseria meningitidis (the meningococcus) causes significant morbidity and mortality in children and young adults worldwide through epidemic or sporadic meningitis and/or septicemia. In this review, we describe the biology, microbiology, and epidemiology of this exclusive human pathogen. N.meningitidis is a fastidious, encapsulated, aerobic gram-negative diplococcus. Colonies are positive by the oxidase test and most strains utilize maltose. The phenotypic classification of meningococci, based on structural differences in capsular polysaccharide, lipooligosaccharide (LOS) and outer membrane proteins, is now complemented by genome sequence typing (ST). The epidemiological profile of N. meningitidis is variable in different populations and over time and virulence of the meningococcus is based on a transformable/plastic genome and expression of certain capsular polysaccharides (serogroups A, B, C, W-135, Y and X) and non-capsular antigens. N. meningitidis colonizes mucosal surfaces using a multifactorial process involving pili, twitching motility, LOS, opacity associated, and other surface proteins. Certain clonal groups have an increased capacity to gain access to the blood, evade innate immune responses, multiply, and cause systemic disease. Although new vaccines hold great promise, meningococcal infection continues to be reported in both developed and developing countries, where universal vaccine coverage is absent and antibiotic resistance increasingly more common.
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Nod2 Is a General Sensor of Peptidoglycan through Muramyl Dipeptide (MDP) Detection
Girardin, S. E., Boneca, I. G., Viala, J., Chamaillard, M., Labigne, A., Thomas, G., Philpott, D. J., & Sansonetti, P. J. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.c200651200 · Cited by 2,408
HUMAN IMMUNITY TO THE MENINGOCOCCUS
Goldschneider, I., Gotschlich, E. C., & Artenstein, M. S. (1969) · The Journal of Experimental Medicine · doi:10.1084/jem.129.6.1307 · Cited by 1,294
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Self-citationComplete Genome Sequence of Neisseria meningitidis Serogroup B Strain MC58
Tettelin, H., Saunders, N. J., Heidelberg, J., Jeffries, A. C., Nelson, K. E., Eisen, J. A., Ketchum, K. A., Hood, D. W., Peden, J. F., Dodson, R. J., et al. (2000) · Science · doi:10.1126/science.287.5459.1809 · Cited by 1,097
HUMAN IMMUNITY TO THE MENINGOCOCCUS
Goldschneider, I., Gotschlich, E. C., & Artenstein, M. S. (1969) · The Journal of Experimental Medicine · doi:10.1084/jem.129.6.1327 · Cited by 995
Epidemic meningitis, meningococcaemia, and Neisseria meningitidis
Stephens, D. S., Greenwood, B., & Brandtzaeg, P. (2007) · The Lancet · doi:10.1016/s0140-6736(07)61016-2 · Cited by 978
Self-citationComplete DNA sequence of a serogroup A strain of Neisseria meningitidis Z2491
Parkhill, J., Achtman, M., James, K. D., Bentley, S. D., Churcher, C., Klee, S. R., Morelli, G., Basham, D., Brown, D., Chillingworth, T., et al. (2000) · Nature · doi:10.1038/35006655 · Cited by 704
Effectiveness of meningococcal serogroup C conjugate vaccine 4 years after introduction
Trotter, C. L., Andrews, N. J., Kaczmarski, E. B., Miller, E., & Ramsay, M. E. (2004) · The Lancet · doi:10.1016/s0140-6736(04)16725-1 · Cited by 571
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Cited by
Pelton, S. I. (2016) · Journal of Adolescent Health · doi:10.1016/j.jadohealth.2016.04.012 · Cited by 199
Metadata
- Authors
- Rouphael, N. G., & Stephens, D. S.
- Venue
- Methods in Molecular Biology
- Publisher
- Humana Press
- Published
- 2011-09-09
- Volume
- 799
- Pages
- 1-20
- ISSN
- 1064-3745 (ISSN-L)
- 1940-6029
- OpenAlex
- W1532933231
- Cited by
- 425
- References
- 108
- FWCI
- 24.35
- Type
- book chapter
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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