Transformation, normalization, and batch effect in the analysis of mass spectrometry data for omics studies,
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Batch effects are common and often much more pronounced in mass spectrometry-based data, even when the same physical instrument is used and the same data type is being generated.
“For example, batch effects are common and often much more pronounced in mass spectrometry-based data (Mertens, 2016; Phua et al., 2022; e.g., Han and Li, 2020), even when the same physical instrument is used and the same data type is being generated.”
From Missing data in multi-omics integration: Recent advances through artificial intelligence (2023) · cites this paper as Mertens, 2016
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Missing data in multi-omics integration: Recent advances through artificial intelligence
Flores, J. E., Claborne, D. M., Weller, Z. D., Webb-Robertson, B.-J. M., Waters, K. M., & Bramer, L. M. (2023) · Frontiers in Artificial Intelligence · doi:10.3389/frai.2023.1098308 · Cited by 181 · see citing works
“effects are common and often much more pronounced in mass spectrometry-based data (Mertens, 2016; Phua et al., 2022; e.g., Han and Li, 2020), even when the same physical instrument is”
BackgroundMulti-Omics Approaches to Define Calcific Aortic Valve Disease Pathogenesis
Blaser, M. C., Kraler, S., Lüscher, T. F., & Aikawa, E. (2021) · Circulation Research · doi:10.1161/circresaha.120.317979 · Cited by 109 · see citing works
- Authors
- Mertens, B. J. A.
- Affiliations
- Leiden University Medical Center (NL)
- Corresponding author
- Mertens, Bart J. A.
- ORCID
- Mertens, Bart J. A.
- Venue
- Statistical Analysis of Proteomics, Metabolomics, and Lipidomics Data Using Mass Spectrometry
- Publisher
- Springer International Publishing
- Published
- 2016-12-16
- Pages
- 1-21
- OpenAlex
- W2431351132
- Cited by
- 30
- References
- 21
- Citations by year
- 2026: 3 · 2025: 6 · 2023: 4 · 2022: 3 · 2021: 3 · 2020: 5 · 2019: 2 · 2018: 2 · 2016: 2
- FWCI
- 5.66
- Type
- book chapter
- Language
- en
- Open access
- green
- arxiv.org
- Locations
- Springer eBooks (publishedVersion)
- arXiv (Cornell University) (publishedVersion)
- arXiv (Cornell University)
- Topics
- Physical Sciences › Chemistry › Spectroscopy › Advanced Proteomics Techniques and Applications
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Metabolomics and Mass Spectrometry Studies
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gene expression and cancer classification
- Keywords
- data transformation, normalization, batch effects, mass spectrometry data, omics data analysis, proteomics, metabolomics, data preprocessing
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