CoChat
Sign Up
Cited by 678Motor Control and AdaptationNeuroscience and Music PerceptionVestibular and auditory disorders

Dissociation of the lateral and medial cerebellum in movement timing and movement execution

Ivry, R. B., Keele, S. W., Diener, H. C.·1988·Experimental Brain Research
DOI 10.1007/bf00279670
Open this paper in CoChat — free account

Abstract

In a previous study (Ivry and Keele, in press), cerebellar patients were found to be impaired on both a motor and a perceptual task which required accurate timing. This report presents case study analyses of seven patients with focal lesions in the cerebellum. The lesions were predominantly in the lateral, hemispheric regions for four of the patients. For the remaining three patients, the lesions were centered near the medial zone of the cerebellum. The clinical evaluation of the patients also was in agreement with the different lesion foci: lateral lesions primarily impaired fine motor coordination, especially apparent in movements with the distal extremities and medial lesions primarily disturbed balance and gait. All of the patients were found to have increased variability in performing rhythmic tapping when tapping with an effector (finger or foot) ipsilateral to the lesion in comparison to their performance with a contralateral effector. Separable estimates of a central timekeeper component and an implementation component were derived from the total variability scores following a model developed by Wing and Kristofferson (1973). This analysis indicated that the poor performance of patients with lateral lesions can be attributed to a deficit in the central timing process. In contrast, patients with medial lesions are able to accurately determine when to make a response, but are unable to implement the response at the desired time. A similar dissociation between the lateral and medial regions has been observed on a time perception task in patients with cerebellar atrophy. It is concluded that the lateral regions of the cerebellum are critical for the accurate functioning of an internal timing system.

Integrity signals

Registry

Crossref · 10.1007/bf00279670

Cites

50 of 50 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Movements require precise spatiotemporal coordination of dozens of muscles, and the cerebellum is believed to coordinate the precise timing of muscle activities.

    “Movements, even simple ones, require precise spatiotemporal coordination of dozens of muscles and it is believed that the cerebellum is involved in coordinating the precise timing of muscle activities [215–217].”

    From Consensus Paper: Pathological Role of the Cerebellum in Autism (2012) · cites this paper as [216]

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Related

Authors
Ivry, R. B., Keele, S. W., & Diener, H. C.
Affiliations
  • University of Oregon (US)
  • University of Tübingen (DE)
ORCID
Venue
Experimental Brain Research
Publisher
Springer Science and Business Media LLC
Published
1988
Volume
73
Issue
1
Pages
167-180
ISSN
  • 0014-4819 (ISSN-L)
  • 1432-1106
DOI
10.1007/bf00279670
OpenAlex
W2083620103
Cited by
678
References
50
Citations by year
2026: 5 · 2025: 12 · 2024: 6 · 2023: 11 · 2022: 10 · 2021: 8 · 2020: 12 · 2019: 5 · 2018: 9 · 2017: 20 · 2016: 13 · 2015: 15 · 2014: 16 · 2013: 25 · 2012: 16
FWCI
3.51
Type
journal article
Language
en
Open access
closed
Licence
www.springer.com/tdm (tdm)
Locations
  • Experimental Brain Research (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Motor Control and Adaptation
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Neuroscience and Music Perception
  • Life Sciences › Neuroscience › Neurology › Vestibular and auditory disorders
Keywords
cerebellum, lateral cerebellum, movement timing, movement execution, rhythmic tapping, movement variability, cerebellar lesions, cerebellar atrophy, time perception, fine motor coordination, gait and balance
MeSH terms
Adult, Aged, Cerebellar Diseases, Cerebellum, Female, Humans, Male, Middle Aged, Psychomotor Performance, Reaction Time, Tomography, X-Ray Computed

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review