Destruction of dopamine in the nucleus accumbens selectively attenuates cocaine but not heroin self-administration in rats

Pettit, Hugh O., Ettenberg, Aaron, Bloom, Floyd E., Koob, George F.·1984·Psychopharmacology

Cited by (646)

Items 501–600 of 646

  1. Dopamine and mental illness: And what about the mesocortical dopamine system?
    Jean‐Pol Tassin · 1987 · Behavioral and Brain Sciences
  2. PYY3-36 infused systemically or directly into the VTA attenuates fentanyl seeking in male rats
    Antonia Caffrey, Enzo Lavecchia, R. Merkel, Yafang Zhang, Kylie S. Chichura, Matthew R. Hayes, Robert P. Doyle, Heath D. Schmidt · 2023 · Neuropharmacology
  3. Voltage-gated potassium channels control extended access cocaine seeking: a role for nucleus accumbens astrocytes
    Mengfan Xia, Tanner L. Anderson, Emily R. Prantzalos, Tara R. Hawkinson, Harrison A. Clarke, Shannon B. Keohane, Ramon C. Sun, Jill R Turner, Pavel Ivanovich Ortinski · 2023 · Neuropsychopharmacology
  4. Pan‐striatal reduction in the expression of the astrocytic dopamine transporter precedes the development of dorsolateral striatum dopamine‐dependent incentive heroin seeking habits
    Tristan J. Hynes, Maxime Fouyssac, Mickaël Puaud, Dhaval Joshi, Chloe S. Chernoff, Sonja Stiebahl, Lola Michaud, David Belin · 2024 · European Journal of Neuroscience
  5. Common and distinct drug cue reactivity patterns associated with cocaine and heroin: An fMRI meta-analysis
    Jordan Michelle Dejoie, Nicole Senia, Anna B. Konova, David Victor Smith, Dominic S. Fareri · 2024 · Imaging Neuroscience
  6. A high-affinity cocaine binding site associated with the brain acid soluble protein 1
    Maged M. Harraz, Adarsha P. Malla, Evan R. Semenza, Maria Shishikura, Manisha Singh, Yun Hwang, In Guk Kang, Young Jun Song, Adele M. Snowman, Pedro Cortés et al. · 2022 · Proceedings of the National Academy of Sciences
  7. CRF antagonism within the ventral tegmental area but not the extended amygdala attenuates the anxiogenic effects of cocaine in rats
    Aaron Ettenberg, Samuel W. Cotten, Michael A. Brito, Adam K. Klein, Tatum A. Ohana, Benjamin D. Margolin, Alex Wei, Jennifer M. Wenzel · 2015 · Pharmacology Biochemistry and Behavior
  8. The dopamine antagonist cis-flupenthixol blocks the expression of the conditioned positive but not the negative effects of cocaine in rats
    Jennifer M. Wenzel, Zu‐In Su, Kerisa Shelton, Hiram M. Dominguez, Victoria A. von Furstenberg, Aaron Ettenberg · 2013 · Pharmacology Biochemistry and Behavior
  9. Neurochemical and Neurobehavioral Consequences of Methamphetamine Abuse
    Colin N. Haile · 2007 · CRC Press eBooks
  10. Interactions of Buprenorphine and Selective Dopamine Receptor Antagonists in the Rat Nucleus Accumbens
    Kwaku D. Nantwi, Shawn D. Hicks, David Bradley, Eugene P. Schoener · 1998 · General Pharmacology The Vascular System
  11. The effects of medial prefrontal cortex infusions of cocaine in a runway model of drug self-administration: Evidence of reinforcing but not anxiogenic actions
    Daniel D. Guzman, Justin M. Moscarello, Aaron Ettenberg · 2009 · European Journal of Pharmacology
  12. The prefrontal cortex — accumbens circuit: Who's in charge?
    George Eugene Jaskiw, Daniel R. Weinberger · 1987 · Behavioral and Brain Sciences
  13. Intrategmental infusion of cocaine decreases dopamine release and enhances norepinephrine release in the medial prefrontal cortex
    Wynn H.T. Pan, Nien-Hsien Chen, Fei-Yu Tsai, Hui-ying Liao · 1996 · European Journal of Pharmacology
  14. Role of opioidergic mechanisms and GABA uptake inhibition in the heroin-induced discriminative stimulus effects in rats.
    Wojciech Solecki, T KROWKA, Małgorzata Filip, Ryszard Przewłocki · 2005 · PubMed
  15. Time-dependent recovery from the effects of 6-hydroxydopamine lesions of the rat nucleus accumbens on cocaine self-administration and the levels of dopamine in microdialysates
    Glen M. Sizemore, Conchita Co, Timothy R. Koves, Thomas Jeff Martin, James E. Smith · 2004 · Psychopharmacology
  16. Mu opioid receptors expressed in striatal D2 medium spiny neurons have divergent contributions to cocaine and morphine reward
    Bailey C. Remmers, Amélia Nicot, Kanako Matsumura, Polina N. Lyuboslavsky, In Bae Choi, Yiru Ouyang, Lauren K. Dobbs · 2025 · Neuroscience
  17. A GLP‐1R/Y1 receptor/Y2 receptor triple agonist decreases fentanyl‐evoked dopamine release in the nucleus accumbens and attenuates fentanyl taking and seeking in rats
    Antonia Caffrey, Enzo Lavecchia, Kylie S. Chichura, Matthew R. Hayes, Robert P. Doyle, Heath D. Schmidt · 2025 · British Journal of Pharmacology
  18. Animal Models in Addiction Research
    David Belin, Jeffrey W. Dalley · 2012 · Springer eBooks
  19. Serotonin and Reward-Related Behavior: Focus on 5-HT2C Receptors
    Paul J. Fletcher, Guy A. Higgins · 2010 · The Receptors
  20. Dextromethorphan and bupropion reduces high level remifentanil self-administration in rats
    Graham Blair, Corinne Wells, Ashley Ko, John Modarres, Caroline Pace, James M. Davis, Amir H. Rezvani, Jed E. Rose, Edward D. Levin · 2020 · Pharmacology Biochemistry and Behavior
  21. Opioids
    George F. Koob, Michel Le Moal · 2006 · Elsevier eBooks
  22. Neurobiology of addiction and recovery: The brain, the drive for the drug, and the 12-step fellowship
    Mark S. Gold · 1994 · Journal of Substance Abuse Treatment
  23. Behavioral Pharmacology of Cocaine
    SHARON L. WALSH · 1998 · Springer eBooks
  24. Preclinical Behavioral Models for Addressing Unmet Needs in Opiate Addiction
    Gery Schulteis, Lisa H. Gold, George F. Koob · 1997 · Seminars in Neuroscience
  25. Cocaine actions on rat prefrontal cortical and hippocampal dentate granule neurons in vitro
    Shokrollah S. Jahromi, Stephen Schertzer, Peter Louis Carlen · 1993 · Synapse
  26. Glutamate and the Self-Administration of Psychomotor-Stimulant Drugs
    Paul Vezina, Nobuyoshi Suto · 2002 · Humana Press eBooks
  27. Can the incentive-sensitization theory of addiction incorporate addiction to opioid drugs?
    Terry E. Robinson, Kent C. Berridge · 2026 · Psychopharmacology
  28. Elevated platelet vesicular monoamine transporter 2 in former heroin addicts maintained on methadone
    Karin Schwartz, Isachar Herman, G. Peer, Abraham Weizman, Moshe Rehavi · 2006 · Journal of Neural Transmission
  29. Efectos de la cocaína en el ser humano
    E. Ambrosio Flores · 2008 · Trastornos Adictivos
  30. Spicy Food Preference and Risk for Alcohol Dependence in Korean
    Ji-Hun Park, Sung‐Gon Kim, Ji-Hoon Kim, Jin-Seong Lee, Woo‐Young Jung, Hyeon‐Kyeong Kim · 2017 · Psychiatry Investigation
  31. Modeling Substance Abuse for Applications in Proteomics
    Scott E. Hemby, Nilesh S. Tannu · 2009 · Methods in molecular biology
  32. Effects of neonatal dopaminergic lesion on oral cocaine self-administration in rats: Higher female vulnerability to cocaine consumption
    Laísa S. Umpierrez, Luana Freese, Felipe Borges Almeida, Priscila A. Costa, Paulo Ricardo Fernandes, Maurício Schüler Nin, Marilise Fraga de Souza, Helena Maria Tannhauser Barros · 2021 · Pharmacology Biochemistry and Behavior
  33. A proposed resolution to the paradox of drug reward: Dopamine's evolution from an aversive signal to a facilitator of drug reward via negative reinforcement
    Ryan A. Ting‐A‐Kee, Andrew Heinmiller, Derek van der Kooy · 2015 · Neuroscience & Biobehavioral Reviews
  34. Sensitivity to self-administered cocaine within the lateral preoptic–rostral lateral hypothalamic continuum
    David J. Barker, Brendan M. Striano, Kevin R. Coffey, David H. Root, Anthony P. Pawlak, Olivia A. Kim, Julianna M. Kulik, Anthony T. Fabbricatore, Mark O. West · 2014 · Brain Structure and Function
  35. Positron emission tomography in Parkinson’s disease: insights into impulsivity
    Adam J. Stark, Daniel O. Claassen · 2017 · International Review of Psychiatry
  36. Neuroanatomical Bases of the Reinforcing Stimulus Effects of Cocaine
    S. Barak Caine · 1998 · Elsevier eBooks
  37. Structural and Functional Neuroimaging of the Effects of Cocaine in Human and Nonhuman Primates
    Linda J. Porrino, David Huston-Lyons, Sharon R. Letchworth, Cory S. Freedland, Michael A. Nader · 2002 · Humana Press eBooks
  38. Mice deficient in protein tyrosine phosphatase receptor type Z (PTPRZ) show reduced responsivity to methamphetamine despite an enhanced response to novelty
    Akihiro Fujikawa, Yukihiro Noda, Hideko Yamamoto, Naomi Tanga, Gaku Sakaguchi, Satoko Hattori, Wen‐Jie Song, Ichiro Sora, Toshitaka Nabeshima, Goro Katsuura et al. · 2019 · PLoS ONE
  39. Endocannabinoid Signaling in Reward and Addiction: From Homeostasis to Pathology
    Sarah A. Laredo, William Marrs, Loren H. Parsons · 2017 · Springer eBooks
  40. Neuropsychopharmacology: Are We Ready for a Paradigm Shift?
    Roger E. Meyer · 1996 · Neuropsychopharmacology
  41. PRECLINICAL INVESTIGATIONS OF GLYT-1 INHIBITION AS A NEW CONCEPT FOR TREATMENT OF ALCOHOL DEPENDENCE
    Helga Höifödt Lidö · 2011
  42. Lack of effect of the combination of metyrapone and oxazepam on brain dopamine
    Courtney M. Keller, Nicholas E. Goeders · 2019 · Brain Research
  43. Neurobiological theories of addiction
    George F. Koob, Michael A. Arends, Mandy L. McCracken, Michel Le Moal · 2019 · Elsevier eBooks
  44. Accentuated Paralimbic and Reduced Mesolimbic D2/3-Impulsivity Associations in Parkinson's Disease
    Adam J. Stark, Alexander K. Song, Kalen J. Petersen, Kaitlyn R. Hay, Ya‐Chen Lin, Paula Trujillo, Hakmook Kang, Jenna M. Collazzo, Manus Joseph Donahue, David Harold Zald et al. · 2023 · Journal of Neuroscience
  45. Tonic opioid inhibition of the subiculo‐accumbens pathway
    Robert L. Hakan · 2001 · Synapse
  46. The Dopamine Transporter and Addiction
    William M. Meil, John W. Boja · 2007 · CRC Press eBooks
  47. An electrophysiologist's eye view of the basal ganglia
    Anthony A. Grace · 1987 · Behavioral and Brain Sciences
  48. The ghost in the machine: What if the midbrain output is excitatory?
    James H. Fallon · 1987 · Behavioral and Brain Sciences
  49. The use of a biopsy punch in surgical preparation of drug self-administering animals
    Fletcher A. Reynolds, Christine L. Duvauchelle, Conan H. Kornetsky · 1994 · Pharmacology Biochemistry and Behavior
  50. Dopamine and mental illness: Phenomenological and anatomical considerations
    Ann E. Kelley · 1987 · Behavioral and Brain Sciences
  51. Which Molecular and Cellular Actions of Ethanol Mediate Reinforcement?
    Floyd E. Bloom · 1989 · Springer eBooks
  52. Basal Forebrain Involvement in Self-Administration of Drugs of Abuse
    Linda J. Porrino, Steven I. Dworkin, James E. Smith · 1991 · Advances in experimental medicine and biology
  53. Neurobiology of opioid use disorder
    Jessica A. Cucinello‐Ragland, Tania Lintz, José A. Morón · 2025 · Elsevier eBooks
  54. Neurobiología de la adicción a opiáceos.
    Olga Valverde, Rafael J. Maldonado · 2005 · Redalyc (Universidad Autónoma del Estado de México)
  55. Reduced dopamine release in Dcc haploinsufficiency male mice abolishes the rewarding effects of cocaine but not those of morphine and ethanol
    Emmanuel Darcq, Dominique Nouel, Giovanni Hernández, Matthew Pokinko, Polina Ash, Luc Moquin, Alain P. Gratton, Brigitte Lina Kieffer, Cecilia Flores · 2022 · Psychopharmacology
  56. 8.2 Dopaminergic Mechanisms in Drug-Seeking Habits and the Vulnerability to Drug Addiction
    Barry J. Everitt, David Belin, Jeffrey W. Dalley, Trevor William Robbins · 2009 · Oxford University Press eBooks
  57. Opioids
    George F. Koob, Michael A. Arends, Mandy L. McCracken, Michel Le Moal · 2023 · Elsevier eBooks
  58. Neurobiological Basis of Drug Reward and Reinforcement
    David M. Lovinger · 2010 · Springer eBooks
  59. The neuropathology of schizophrenia, mania, and depression: Diseases of cognitive initiation and switching?
    Eliot L. Gardner · 1987 · Behavioral and Brain Sciences
  60. Intracellular considerations in models of psychopathology
    Douglas L. Chute · 1987 · Behavioral and Brain Sciences
  61. Effect of kinurenic acid on the acquisition of intravenous morphine self-administration habit by rats
    Anton Bespalov, Edwin E. Zvartau · 1996 · Bulletin of Experimental Biology and Medicine
  62. Neural circuit models of psychopathology: Dancing on the precipice of neuromythology?
    H. Christian Fibiger · 1987 · Behavioral and Brain Sciences
  63. Opioid Analgesics
    L A Dykstra · 1996 · Handbook of experimental pharmacology
  64. Dopamine Receptors: Neurotherapeutic Targets for Substance Use Disorders
    Ashley N. Nilson, Daniel Eric Felsing, John Allen · 2022 · Wiley eBooks
  65. Carbamazepine in the Treatment of Cocaine-Induced Disorders
    Susan R.B. Weiss, Robert M. Post, Thomas G Aigner · 1992 · Humana Press eBooks
  66. Drug self-administration, drug-specific behaviors, and neurobehavioral deep learning analyses
    Nicholas J. Beacher, Michael W. Wang, Jan Shanelle Juan Iringan, Caroline E. Clark, Ginevra D’Ottavio, Matthew C. Broomer, Da‐Ting Lin · 2025 · Addiction Neuroscience
  67. We must look beyond primary reinforcement to understand nicotine use in women
    Kathleen R. McNealy, Scott T. Barrett, Rick A. Bevins · 2026 · Frontiers in Neuroendocrinology
  68. Mu-opioid and nociceptin receptors show divergent, cell-type-specific actions in the mesocorticolimbic reward system in opioid use disorder
    Marie‐Charlotte Allichon, Jeanne Espinosa, Rebecca H. Cole, Mei-Chuan Ko, Peter Vanhoutte, Max E. Joffe · 2026 · Frontiers in Cellular Neuroscience
  69. Environmental Modulation of Drug Taking
    Aldo Badiani, Daniele Caprioli, Arianna Testa, Maria Teresa De Luca, Michele Celentano · 2010 · Neuromethods
  70. Neurochemistry of Drug Abuse
    Julie K. Staley, Kelly Cosgrove · 2006 · CRC Press eBooks
  71. Neuronal Mediation of Addictive Behavior
    George F. Koob · 1998 · CRC Press eBooks
  72. Addictions
    Eduardo R. Butelman, Brian Reed, Vadim P. Yuferov, Mary Jeanne Kreek · 2022 · Elsevier eBooks
  73. Midbrain (VTA) circuits
    Marisela Morales, Maria Flavia Barbano · 2023 · Elsevier eBooks
  74. Cocaine effects on striatal dynorphin and CART neuropeptides : Association to mood disorder
    Pernilla Fagergren · 2003 · Figshare
  75. Toward a unified neuropsychiatric hypothesis
    Neal R. Swerdlow, George F. Koob · 1987 · Behavioral and Brain Sciences
  76. Where have all the peptides gone?
    Peter W. Kalivas · 1987 · Behavioral and Brain Sciences
  77. The “extended amygdala” as a receptor area for psychotherapeutic drugs
    George F. Alheid, Lennart Heimer · 1987 · Behavioral and Brain Sciences
  78. Unified theories of psychoses and affective disorders: Are they feasible without accurate neural models of cognition and emotion?
    Anthony G. Phillips · 1987 · Behavioral and Brain Sciences
  79. Psychopharmacology of psychosis: Still looking for missing links
    Janice R. Stevens · 1987 · Behavioral and Brain Sciences
  80. Neuropsychiatry: Pitfalls of inferring functional mechanisms from observed drug effects
    Philippe Soubrié, Pascale Carnoy · 1987 · Behavioral and Brain Sciences
  81. GDNF/RET signalling in regulation of brain dopaminergic systems: significance for drug addiction
    Mikko Airavaara · 2006 · Työväentutkimus Vuosikirja
  82. Substratums neurobiologiques de la tolérance et de la dépendance aux opiacés
    Hélène Ollat · 1992 · Douleur et Analgésie
  83. Neurochemical Predictors and Correlates of Vulnerability to Cocaine Use
    Roy King, Christopher R. Flowers · 1996 · PsycEXTRA Dataset
  84. 8.1 The Role of Dopamine in the Motivational Vulnerability to Addiction
    George F. Koob, Michel Le Moal · 2009 · Oxford University Press eBooks
  85. Neuronal Mediation of Addictive Behavior
    George F. Koob · 2019 · CRC Press eBooks
  86. The Role of Serotonin in MDMA Self-administration in Rats
    Sarah Bradbury · 2014
  87. Cortical and Sub-Cortical Effects in Primate Models of Cocaine Use: Implications for Addiction and the Increased Risk of Psychiatric Illness
    Charles W. Bradberry · 2010 · Springer eBooks
  88. The preclinical study of methamphetamine self-administration and the underlying molecular biology and proteomics changes in the reward system
    Bosch, Peter · 2013
  89. Effects of mitragynine on morphine and methamphetamine addiction in animal models of addiction
    Rittinarong Meepong · 2017
  90. Effects of serotonin agonists LSD and 25CN-NBOH on conditioned place preference and on synaptic plasticity of VTA dopamine neurons in mice
    Lauri V. Elsilä, Elina I. Nagaeva, Jari-Pekka Luukkonen, Esa R. Korpi · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  91. Sexual behavior causes activation and functional alterations of mesolimbic systems : neurobiology of motivation and reward.
    Margaret E. Balfour · 2003 · OhioLink ETD Center (Ohio Library and Information Network)
  92. Rapid Adaptation of Dopamine D2 Receptor Responses in the Brain and Blood Following Acute Ethanol
    Ryan J. Folsom · 2014 · ScholarsArchive (Brigham Young University)
  93. Vulnerability to cocaine : role of stress hormones
    Igle Jan de Jong · 2007
  94. Neurochemistry of Opiate Dependence
    Rafael J. Maldonado, Luis Stinus, George F. Koob · 1996 · Neuroscience intelligence unit
  95. Molecular mechanisms underlying the actions of psychoactive drugs in the basal ganglia : Focus on cannabinoids and morphine
    Anders Borgkvist · 2008 · Figshare
  96. Effects of chronic nicotine on behavioural and neurochemical responses to morphine
    Tanja Kivinummi · 2009 · Työväentutkimus Vuosikirja
  97. Mechanisms mediating sex differences in the effects of cocaine
    Wei Zhao · 2008 · Deep Blue (University of Michigan)
  98. The Effects of Rhes on Opioid Analgesia
    Franklin H. Lee · 2010 · ScholarWorks @ The University of New Orleans (The University of New Orleans)
  99. Efeito da administração aguda e repetida de fencanfamina sobre o valor reforçado do estímulo
    Miriam García‐Mijares · 2000 · Digital Library of Theses and Dissertations (Universidade de São Paulo)
  100. Prefrontal cortex D1 receptor regulation of mesolimbic dopamine and cocaine self-administration
    Christopher M. Olsen · 2004 · Texas ScholarWorks (Texas Digital Library)