Interspecies scaling, allometry, physiological time, and the ground plan of pharmacokinetics

Cited by (398)

Items 101–200 of 398

1. Internal exposure-based pharmacokinetic evaluation of potential for biopersistence of 6:2 fluorotelomer alcohol (FTOH) and its metabolites
   Shruti V. Kabadi, Jeffrey W. Fisher, Jason L. Aungst, Penelope A. Rice · 2018 · Food and Chemical Toxicology
2. Pharmacokinetics of rituximab in a pediatric patient with therapy-resistant nephrotic syndrome
   C. E. Counsilman, C. M. Jol-van der Zijde, J. Stevens, K. Cransberg, R. Bredius, R. Sukhai · 2015 · Pediatric nephrology (Berlin, West)
3. Formed and preformed metabolites: facts and comparisons
   K. Pang, M. Morris, Huadong Sun · 2008 · The Journal of pharmacy and pharmacology
4. A Model for Transport and Dispersion in the Circulatory System Based on the Vascular Fractal Tree
   A. Dokoumetzidis, P. Macheras · 2003 · Annals of Biomedical Engineering
5. Modeling and allometric scaling of s(+)-ketoprofen pharmacokinetics and pharmacodynamics: a retrospective analysis.
   E. Lepist, W. Jusko · 2004 · Journal of Veterinary Pharmacology and Therapeutics
6. Prediction of Vss from In Vitro Tissue-Binding Studies
   Loren Berry, Jonathan T. Roberts, Xuhai Be, Zhiyang Zhao, Min-Hwa Jasmine Lin · 2009 · Drug Metabolism and Disposition
7. Feasibility of Developing a Neural Network for Prediction of Human Pharmacokinetic Parameters from Animal Data
   A. Hussain, Robert D. Johnson, N. Vachharajani, W. Ritschel · 1993 · Pharmaceutical Research
8. Meta-Assessment of Metformin Absorption and Disposition Pharmacokinetics in Nine Species
   Yoo‐Seong Jeong, William J. Jusko · 2021 · Pharmaceuticals
9. Quantitative PK–PD Model-Based Translational Pharmacology of a Novel Kappa Opioid Receptor Antagonist Between Rats and Humans
   Cheng Chang, W. Byon, Yi-Feng Lu, L. Jacobsen, L. Badura, A. Sawant-Basak, E. Miller, Jing Liu, S. Grimwood, E. Wang et al. · 2011 · AAPS Journal
10. Mixed Effect Modeling of Sumatriptan Pharmacokinetics During Drug Development. I: Interspecies Allometric Scaling
    V. Cosson, E. Fuseau, C. Efthymiopoulos, A. Bye · 1997 · Journal of pharmacokinetics and biopharmaceutics
11. Animal-to-Human Extrapolation of the Pharmacokinetic and Pharmacodynamic Properties of Buprenorphine
    A. Yassen, E. Olofsen, Jingmin Kan, A. Dahan, M. Danhof · 2007 · Clinical Pharmacokinetics
12. Preclinical Assessment of the Absorption and Disposition of the Phosphatidylinositol 3-Kinase/Mammalian Target of Rapamycin Inhibitor GDC-0980 and Prediction of Its Pharmacokinetics and Efficacy in Human
    Laurent Salphati, Jodie Pang, Emile G. Plise, Leslie B. Lee, Alan G. Olivero, Wei Wei Prior, Deepak Sampath, Susan Wong, Xiaolin Zhang · 2012 · Drug Metabolism and Disposition
13. Prediction of Exposure–Response Relationships to Support First-in-Human Study Design
    John P. Gibbs · 2010 · The AAPS Journal
14. Comparative pharmacokinetics of benzodiazepines in dog and man
    H. Boxenbaum · 1982 · Journal of pharmacokinetics and biopharmaceutics
15. In Silico Prediction of Oral Bioavailability
    Joseph V. Turner, S. Agatonovic-Kustrin · 2007 · Elsevier eBooks
16. Neurovascular and neuroimaging effects of the hallucinogenic serotonin receptor agonist psilocin in the rat brain
    Aisling Spain, Clare Howarth, Alexandre A. Khrapitchev, Trevor Sharp, Nicola R. Sibson, Chris J. Martin · 2015 · Neuropharmacology
17. Prediction of volume of distribution at steady state in humans: comparison of different approaches
    Peng Zou, Nan Zheng, Yongsheng Yang, Lawrence X. Yu, Duxin Sun · 2012 · Expert Opinion on Drug Metabolism & Toxicology
18. Allometric scaling of pegylated liposomal anticancer drugs
    Whitney Paige Caron, Harvey J. Clewell III M.A., Robert L. Dedrick, Ramesh K. Ramanathan, Whitney L. Davis, Ning Y. Yu, Margaret Eleanor Tonda, Jan H.M. Schellens, Jos H. Beijnen, William C. Zamboni · 2011 · Journal of Pharmacokinetics and Pharmacodynamics
19. Metabotropic glutamate receptor modulation, translational methods, and biomarkers: relationships with anxiety
    Rebecca E. Nordquist, Thomas Steckler, Joseph G. Wettstein, Claire E. Mackie, Will P. J. M. Spooren · 2008 · Psychopharmacology
20. Age-Related Differences in Susceptibility to Carcinogenesis: A Quantitative Analysis of Empirical Animal Bioassay Data
    D. Hattis, R. Goble, Abel Russ, M. Chu, Jen Ericson · 2004 · Environmental Health Perspectives
21. Model-based drug development: application of modeling and simulation in drug development
    Tae‐Hwan Kim, Soyoung Shin, Beom Soo Shin · 2017 · Journal of Pharmaceutical Investigation
22. Pharmacokinetics and Pharmacodynamics of Biotech Drugs
    B. Meibohm, H. Derendorf · 2006
23. Physiologically-Based PK/PD Modelling of Therapeutic Macromolecules
    Peter Thygesen, Panos E. Macheras, Achiel Van Peer · 2009 · Pharmaceutical Research
24. Misconceptions and Issues Regarding Allometric Scaling during the Drug Development Process
    Mahmood, Iftekhar · 2018 · Expert Opinion on Drug Metabolism & Toxicology
25. Use of Modeling and Simulation in the Design and Conduct of Pediatric Clinical Trials and the Optimization of Individualized Dosing Regimens
    Chris R. Stockmann, Jeffrey S. Barrett, JK Roberts, Catherine M.T. Sherwin · 2015 · CPT Pharmacometrics & Systems Pharmacology
26. Enantioselective Pharmacokinetics of α-Lipoic Acid in Rats
    Ryota Uchida, Hinako Okamoto, Naoko Ikuta, K. Terao, T. Hirota · 2015 · International Journal of Molecular Sciences
27. The biopharmaceutics and oral bioavailability of two forms of oxytetracycline to the white shrimp, Litopenaeus setiferus☆
    L. Reed, T. Siewicki, J. Shah · 2006
28. A Mathematical Description of the Functionality of Correction Factors Used in Allometry for Predicting Human Drug Clearance
    Tang, Huadong, Mayersohn, Michael · 2005 · Drug Metabolism and Disposition
29. Physiological parameter values for physiologically based pharmacokinetic models in food‐producing animals. Part III: Sheep and goat
    Miao Li, Yu‐Shin Wang, Trevor Elwell‐Cuddy, Ronald E. Baynes, Lisa Ann Tell, Jennifer L. Davis, Fiona P. Maunsell, Jim Edmond Riviere, Zhoumeng Lin · 2020 · Journal of Veterinary Pharmacology and Therapeutics
30. A framework for meta-analysis of veterinary drug pharmacokinetic data using mixed effect modeling.
    Meng-Jie Li, R. Gehring, Zhoumeng Lin, J. Riviere · 2015 · Journal of Pharmacy and Science
31. Preclinical Disposition of GDC-0973 and Prospective and Retrospective Analysis of Human Dose and Efficacy Predictions
    Edna F. Choo, Marcia P. Belvin, Jason W. Boggs, Yuzhong Deng, Klaus P. Hoeflich, Justin Ly, Mark A. Merchant, Christine Orr, Emile G. Plise, Kirk D. Robarge et al. · 2012 · Drug Metabolism and Disposition
32. Preclinical pharmacokinetics and oral bioavailability of BMS-310705, a novel epothilone B analog
    Amrita V. Kamath, Ming Chang, F. Lee, Yue-Ping Zhang, P. Marathe · 2005 · Cancer Chemotherapy and Pharmacology
33. Prediction of Human Oral Plasma Concentration-Time Profiles Using Preclinical Data: Comparative Evaluation of Prediction Approaches in Early Pharmaceutical Discovery
    Van den Bergh, An, Sinha, Vikash, Gilissen, Ron, Straetemans, Roel, Wuyts, Koen, Morrison, Denise, Bijnens, Luc, Mackie, Claire · 2011 · Clinical Pharmacokinetics
34. Nanoparticle Mass Transfer From Lung Airways to Systemic Regions—Part II: Multi-Compartmental Modeling
    Arun V. Kolanjiyil, Clement Kleinstreuer · 2013 · Journal of Biomechanical Engineering
35. Interspecies allometric scaling: prediction of clearance in large animal species: Part II: mathematical considerations
    Marilyn N. Martinez, Iftekhar Mahmood, Robert Paul Hunter · 2006 · Journal of Veterinary Pharmacology and Therapeutics
36. Neuroprotective effects of inter-alpha inhibitor proteins after hypoxic-ischemic brain injury in neonatal rats
    Xiaodi F. Chen, Sakura Nakada, John Edward Donahue, Ray H. Chen, Richard J. Tucker, Joseph Qiu, Yow‐Pin Lim, Edward G. Stopa, Barbara S. Stonestreet · 2019 · Experimental Neurology
37. Serotonin-mediated central fatigue underlies increased endurance capacity in mice from lines selectively bred for high voluntary wheel running.
    Gerald C. Claghorn, I. A. Fonseca, Zoe Thompson, Curtis Barber, T. Garland · 2016 · Physiology and Behavior
38. Acetaminophen in cerebrospinal fluid in children
    C. D. van der Marel, B. Anderson, M. Pluim, T. D. de Jong, A. González, D. Tibboel · 2003 · European Journal of Clinical Pharmacology
39. Of mice, men and nanoparticle biocoronas: are in vitro to in vivo correlations and interspecies extrapolations realistic?
    J. Riviere · 2013 · Nanomedicine
40. Prediction of Human Pharmacokinetics from Animal Data and Molecular Structural Parameters using Multivariate Regression Analysis: Oral Clearance
    Toshihiro Wajima, Kazuya Fukumura, Yoshitaka Yano, Takayoshi Oguma · 2003 · Journal of Pharmaceutical Sciences
41. Prediction of human pharmacokinetics from animal data and molecular structural parameters using multivariate regression analysis: volume of distribution at steady state
    Toshihiro Wajima, Kazuya Fukumura, Yoshitaka Yano, Takayoshi Oguma · 2003 · Journal of Pharmacy and Pharmacology
42. Pharmacologic Considerations in the Disposition of Antibodies and Antibody-Drug Conjugates in Preclinical Models and in Patients
    Andrew T. Lucas, Ryan Robinson, Allison N. Schorzman, Joseph A. Piscitelli, Juan Felipe Razo, William C. Zamboni · 2019 · Antibodies
43. Prediction of brain delivery of ofloxacin, a new quinolone, in the human from animal data
    J. Kawakami, K. Yamamoto, Y. Sawada, T. Iga · 1994 · Journal of pharmacokinetics and biopharmaceutics
44. DNDI-6174 is a preclinical candidate for visceral leishmaniasis that targets the cytochrome bc 1
    Stéphanie Braillard, Martine Keenan, Karen J. Breese, Jacob Heppell, Michael J. Abbott, Rafiqul Islam, David M. Shackleford, Kasiram Katneni, Elly Crighton, Gong Chen et al. · 2023 · Science Translational Medicine
45. Methods to Predict Volume of Distribution
    Kimberly Holt, Swati Nagar, Ken Korzekwa · 2019 · Current Pharmacology Reports
46. Prediction of deoxynivalenol toxicokinetics in humans by in vitro-to-in vivo extrapolation and allometric scaling of in vivo animal data
    Christiane Kruse Fæste, Lada Ivanova, Amin Sayyari, Ulrik Hansen, Tore Sivertsen, Silvio Uhlig · 2018 · Archives of Toxicology
47. Elucidation of Human Amphotericin B Pharmacokinetics: Identification of a New Potential Factor Affecting Interspecies Pharmacokinetic Scaling
    Gabriel Robbie, W. L. Chiou · 1998 · Pharmaceutical Research
48. Scaling of antipyrine intrinsic clearance of unbound drug in 15 mammalian species
    H. Boxenbaum, J. Fertig · 1984 · European journal of drug metabolism and pharmacokinetics
49. Predicting Oral Clearance in Humans
    Vikash K. Sinha, Stefan S. De Buck, Luca A. Fenu, Johan Willem Smit, Marjoleen Nijsen, Ron Gilissen, Achiel Van Peer, Karel Lavrijsen, Claire E. Mackie · 2008 · Clinical Pharmacokinetics
50. Correlation of Unbound Plasma Clearances of Fifteen Extensively Metabolized Drugs Between Humans and Rats
    Chiou, Win L., Hsu, Fung-Hwa · 1988 · Pharmaceutical Research
51. The Pharmacokinetics of Ropivacaine After Intraperitoneal Administration: Instillation Versus Nebulization
    Delphine Betton, N. Greib, H. Schlotterbeck, G. Joshi, G. Ubeaud-Séquier, P. Diemunsch · 2010 · Anesthesia and Analgesia
52. Evaluation of analgesic interaction between morphine, dexmedetomidine and maropitant using hot-plate and tail-flick tests in rats.
    S. R. Karna, K. Kongara, P. Singh, P. Chambers, N. López-Villalobos · 2019 · Veterinary Anaesthesia and Analgesia
53. SC83288 is a clinical development candidate for the treatment of severe malaria
    Stefano Pegoraro, Maëlle Duffey, Thomas D. Otto, Yulin Wang, Roman Rösemann, Roland Baumgartner, Stefanie K. Fehler, Leonardo Lucantoni, Vicky M. Avery, Alicia Moreno Sabater et al. · 2017 · Nature Communications
54. Mathematical modeling and simulation in animal health. Part I: Moving beyond pharmacokinetics
    Jim Edmond Riviere, Johan Gabrielsson, Martin Fink, Jonathan Paul Mochel · 2015 · Journal of Veterinary Pharmacology and Therapeutics
55. Across‐species meta‐analysis of dexamethasone pharmacokinetics utilizing allometric and scaling modeling approaches
    Dawei Song, William J. Jusko · 2021 · Biopharmaceutics & Drug Disposition
56. Effects of Early Chemotherapeutic Treatment on Learning in Adolescent Mice: Implications for Cognitive Impairment and Remediation in Childhood Cancer Survivors
    Emily B. Bisen-Hersh, P. Hineline, E. Walker · 2013 · Clinical Cancer Research
57. ON ALLOMETRY RELATIONS
    Damien J. West, Bruce J. West · 2012 · International Journal of Modern Physics B
58. Allometric scaling of clearance in dogs
    Marilyn N. Martinez, Iftekhar Mahmood, Robert Paul Hunter · 2009 · Journal of Veterinary Pharmacology and Therapeutics
59. Prediction of human oral pharmacokinetics using nonclinical data: examples involving four proprietary compounds
    Aberra Fura, Viral P. Vyas, William Griffith Humphreys, Anjaneya Chimalokonda, David Rodrigues · 2008 · Biopharmaceutics & Drug Disposition
60. Safety, Tolerability and Pharmacokinetic and Pharmacodynamic Learnings from a Double-Blind, Randomized, Placebo-Controlled, Sequential Group First-in-Human Study of the TRPV1 Antagonist, JNJ-38893777, in Healthy Men
    Prasarn Manitpisitkul, A. Mayorga, K. Shalayda, M. De Meulder, Gary Romano, Chen Jun, J. Moyer · 2015 · Clinical drug investigation
61. Prediction of Human Distribution Volumes of Compounds in Various Elimination Phases Using Physiologically Based Pharmacokinetic Modeling and Experimental Pharmacokinetics in Animals
    H. Shimizu, Kosuke Yoshida, Tomohisa Nakada, Koki Kojima, Akihito Ogasawara, Yoshinobu Nakamaru, Hiroshi Yamazaki · 2018 · Drug Metabolism and Disposition
62. Population pharmacokinetics of maslinic acid, a triterpene from olives, after intravenous and oral administration in rats.
    Marta Sánchez-González, H. Colom, G. Lozano-Mena, M. Juan, J. Planas · 2014 · Molecular Nutrition & Food Research
63. Establishing a model for assessing DNA damage in murine brain cells as a molecular marker of chemotherapy-associated cognitive impairment
    Evgeny Y. Krynetskiy, Natalia F. Krynetskaia, Diana Rihawi, Katarzyna Wieczerzak, Victoria Ciummo, Ellen Ann Walker · 2013 · Life Sciences
64. Interspecies scaling of the monoclonal anti‐EGF receptor ior EGF/r3 antibody disposition using allometric paradigm: is it really suitable?
    Jorge Duconge-Soler, Eduardo M. Fernández-Sánchez, Daniel Alvarez · 2004 · Biopharmaceutics & Drug Disposition
65. Current Approaches for Predicting Human PK for Small Molecule Development Candidates: Findings from the IQ Human PK Prediction Working Group Survey
    Carl Petersson, Xin Zhou, Joerg Berghausen, David Álvaro Cebrián, Michael Davies, Kevin DeMent, Peter J. Eddershaw, Arian Emami Riedmaier, Alix F. Leblanc, Nenad Manveski et al. · 2022 · The AAPS Journal
66. Approaches for predicting human pharmacokinetics using interspecies pharmacokinetic scaling
    Hee Eun Kang, Myung Gull Lee · 2011 · Archives of Pharmacal Research
67. Preclinical Metabolism and Disposition of SB939 (Pracinostat), an Orally Active Histone Deacetylase Inhibitor, and Prediction of Human Pharmacokinetics
    Ramesh Jayaraman, Venkatesh Pilla Reddy, Mohammed Khalid Pasha, Haishan Wang, Kanda Sangthongpitag, Pauline Yeo, Chang Yong Hu, Xiaofeng Wu, Xin Liu, Evelyn Mei Ling Goh et al. · 2011 · Drug Metabolism and Disposition
68. Interspecies pharmacokinetic scaling of oltipraz in mice, rats, rabbits and dogs, and prediction of human pharmacokinetics
    S. Bae, Shin J. Lee, Y. Kim, So H. Kim, J. W. Kim, Taekrho Kim, M. Lee · 2005 · Biopharmaceutics & drug disposition
69. Radiation physics for nuclear medicine
    M. Cantone, C. Hoeschen · 2011
70. A Population Pharmacokinetics and Pharmacodynamic Approach To Optimize Tazobactam Activity in Critically Ill Patients
    Shamir N. Kalaria, Mathangi Gopalakrishnan, Emily L. Heil · 2019 · Antimicrobial Agents and Chemotherapy
71. Preclinical pharmacokinetics of the novel PI3K inhibitor GDC-0941 and prediction of its pharmacokinetics and efficacy in human
    Laurent Salphati, Jodie Pang, Emile G. Plise, Bilin Chou, Jason S. Halladay, Alan G. Olivero, Patrick J. Rudewicz, Qingping Tian, Susan Wong, Xiaolin Zhang · 2011 · Xenobiotica
72. Preclinical disposition and pharmacokinetics-pharmacodynamic modeling of biomarker response and tumour growth inhibition in xenograft mouse models of G-573, a MEK inhibitor
    Edna F. Choo, Marcia P. Belvin, Jocelyn Chan, Klaus P. Hoeflich, Christine Orr, Kirk D. Robarge, Xiaoye Yang, Mark Zak, Jason W. Boggs · 2010 · Xenobiotica
73. Biological Characterization of Novel Inhibitors of the Gram-Positive DNA Polymerase IIIC Enzyme
    A. Kuhl, N. Svenstrup, C. Ladel, M. Otteneder, Annegret Binas, Guido Schiffer, M. Brands, T. Lampe, K. Ziegelbauer, H. Rübsamen-Waigmann et al. · 2005 · Antimicrobial Agents and Chemotherapy
74. Prediction of volume of distribution in humans: analysis of eight methods and their application in drug discovery
    Carl Petersson, Orestis Papasouliotis, Marc Lecomte, Lassina Badolo, Hugues Dolgos · 2019 · Xenobiotica
75. Population pharmacokinetic modelling of NS2330 (tesofensine) and its major metabolite in patients with Alzheimer's disease.
    T. Lehr, A. Staab, C. Tillmann, D. Trommeshauser, A. Raschig, H. Schaefer, C. Kloft · 2007 · British Journal of Clinical Pharmacology
76. Interspecies Scaling of Cimetidine–Theophylline Pharmacokinetic Interaction: Interspecies Scaling in Pharmacokinetic Interactions
    A. Gascón, B. Calvo, R. Hernández, A. Domínguez-Gil, J. Pedraz · 1994 · Pharmaceutical Research
77. Allometry, Shallometry!
    D. Fisher, S. Shafer · 2016 · Anesthesia and Analgesia
78. Antimicrobial Dosing in Specific Populations and Novel Clinical Methodologies: Obesity
    Manjunath P. Pai · 2021 · Clinical Pharmacology & Therapeutics
79. Predicting Resolvin D1 Pharmacokinetics in Humans with Physiologically‐Based Pharmacokinetic Modeling
    V. Yellepeddi, Kaustubh Parashar, Spencer M. Dean, K. Watt, J. E. Constance, O. Baker · 2020 · Clinical and Translational Science
80. Current intelligence bulletin 69: NIOSH practices in occupational risk assessment.
    R. Daniels, S. Gilbert, S. Kuppusamy, E. Kuempel, R. Park, S. P. Pandalai, Randall J. Smith, M. Wheeler, C. Whittaker, P. Schulte · 2020
81. Predicting Pediatric Age-Matched Weight and Body Mass Index
    Sherwin K. B. Sy, Eduardo Asín‐Prieto, Hartmut Derendorf, Emil E. Samara · 2014 · The AAPS Journal
82. Pharmacokinetics of TH-302: a hypoxically activated prodrug of bromo-isophosphoramide mustard in mice, rats, dogs and monkeys
    D. Jung, Lin Lin, H. Jiao, Xiao-Hong Cai, Jianxin Duan, M. Matteucci · 2012 · Cancer Chemotherapy and Pharmacology
83. Adrenergic drugs alter both the fluid kinetics and the hemodynamic responses to volume expansion in sheep.
    C. Ewaldsson, L. Vane, G. Kramer, R. Hahn · 2006 · Journal of Surgical Research
84. A semiparametric approach to physiological flow models
    D. Verotta, L. Sheiner, W. Ebling, D. Stanski · 1989 · Journal of pharmacokinetics and biopharmaceutics
85. Generalizations in linear pharmacokinetics using properties of certain classes of residence time distributions. I. Log-convex drug disposition curves
    M. Weiss · 1986 · Journal of pharmacokinetics and biopharmaceutics
86. Physiological pharmacokinetic modeling ofcis-dichlorodiammineplatinum(II) (DDP) in several species
    F. King, R. L. Dedrick, F. Farris · 1986 · Journal of pharmacokinetics and biopharmaceutics
87. Systems Pharmacology Modeling Identifies a Novel Treatment Strategy for Bortezomib-Induced Neuropathic Pain
    P. Bloomingdale, C. Meregalli, K. Pollard, A. Canta, A. Chiorazzi, G. Fumagalli, L. Monza, E. Pozzi, P. Alberti, E. Ballarini et al. · 2022 · Frontiers in Pharmacology
88. Wide size dispersion and use of body composition and maturation improves the reliability of allometric exponent estimates
    Mario González-Sales, N. Holford, Guillaume Bonnefois, J. Desrochers · 2021 · Journal of Pharmacokinetics and Pharmacodynamics
89. Pharmacokinetics and interspecies scaling of a novel, orally-bioavailable anti-cancer drug, SHetA2
    Ankur Sharma, Doris M. Benbrook, Sukyung Woo · 2018 · PLoS ONE
90. The influence of rapid growth in broilers on florfenicol pharmacokinetics – allometric modelling of the pharmacokinetic and haemodynamic parameters
    B. Poźniak, P. Pawłowski, U. Pasławska, Tomasz Grabowski, Agnieszka Suszko, Magdalena Lis, Marcin Świtała · 2017 · British Poultry Science
91. Pharmacokinetics of Belimumab in Children With Systemic Lupus Erythematosus
    Richard J. Dimelow, Beulah Ji, Herbert Struemper · 2020 · Clinical Pharmacology in Drug Development
92. Nano-carriers for drug routeing – towards a new era
    Lakkireddy Harivardhan Reddy, Didier Bazile · 2018 · Journal of drug targeting
93. Population Pharmacokinetic Modeling as a Tool To Characterize the Decrease in Ciprofloxacin Free Interstitial Levels Caused by Pseudomonas aeruginosa Biofilm Lung Infection in Wistar Rats
    B. Torres, V. E. Helfer, Priscila M Bernardes, A. Macêdo, E. I. Nielsen, L. Friberg, T. Dalla Costa · 2017 · Antimicrobial Agents and Chemotherapy
94. Application of a systems pharmacology model for translational prediction of hERG ‐mediated QT c prolongation
    Verena Gotta, Zhiyi Yu, Frank J.S. Cools, Karel Van Ammel, David J. Gallacher, Sandra A. G. Visser, Frederick J. Sannajust, Pierre Morissette, Meindert Danhof, Piet H. van der Graaf · 2016 · Pharmacology Research & Perspectives
95. Model‐Based Assessment of Dosing Strategies in Children for Monoclonal Antibodies Exhibiting Target‐Mediated Drug Disposition
    Songmao Zheng, Puneet Gaitonde, M. Andrew, Megan A. Gibbs, Lawrence J. Lesko, Stephan Schmidt · 2014 · CPT Pharmacometrics & Systems Pharmacology
96. Prediction of oral clearance from in vitro metabolic data using recombinant CYPs: Comparison among well-stirred, parallel-tube, distributed and dispersion models
    Takahito Yamamoto, H. Itoga, Y. Kohno, K. Nagata, Y. Yamazoe · 2005 · Xenobiotica; the fate of foreign compounds in biological systems
97. Development of Antibody-Based Therapeutics
    Mohammad A. Tabrizi, Scott L. Klakamp, Gadi Gazit Bornstein · 2012 · Springer eBooks
98. Preclinical pharmacokinetics and interspecies scaling of ragaglitazar, a novel biliary excreted PPAR dual activator
    Venkata V. Pavankuamr, Chaithanya Vinu, Ramesh Mullangi, Nuggehally R. Srinivas · 2007 · European Journal of Drug Metabolism and Pharmacokinetics
99. Estimation of Attainment of Steady‐State Conditions for Compounds With a Long Half‐Life
    Andreas Krause, Dominik Lott, J. Dingemanse · 2020 · Journal of clinical pharmacology
100. Allometric Scaling Approaches for Predicting Human Pharmacokinetic of a Locked Nucleic Acid Oligonucleotide Targeting Cancer-Associated miR-221
     M. D. Di Martino, M. Arbitrio, M. Fonsi, C. Erratico, F. Scionti, D. Caracciolo, P. Tagliaferri, P. Tassone · 2019 · Cancers