Observations on oligodendrocyte degeneration, the resolution of status spongiosus and remyelination in cuprizone intoxication in mice

Blakemore, W. F.·1972·Journal of Neurocytology

Cited by (217)

Items 101–200 of 217

  1. Differential Expression of miRNAs and Behavioral Change in the Cuprizone-Induced Demyelination Mouse Model
    Seung Ro Han, Yun Hee Kang, Hyungtaek Jeon, Suhyuk Lee, Sang‐Jin Park, D. Song, Sun Seek Min, Sun Seek Min, Myung‐Shin Lee, Myung‐Shin Lee · 2020 · International Journal of Molecular Sciences
  2. Regeneration and repair in multiple sclerosis: The view of experimental pathology
    William F. Blakemore · 2007 · Journal of the Neurological Sciences
  3. Mechanism of demyelination and remyelination in multiple sclerosis
    Yoshio Bandô · 2020 · Clinical and Experimental Neuroimmunology
  4. Cuprizone-induced Demyelination in Mouse Brain is not due to Depletion of Copper
    Megan L. Morgan, Wulin Teo, Yda Hernandez, Craig Brideau, Karen Cummins, Hedwich F. Kuipers, Peter K. Stys · 2022 · ASN NEURO
  5. Endogenous or exogenous oligodendrocytes for remyelination
    William F. Blakemore, Karen‐Amanda Irvine · 2007 · Journal of the Neurological Sciences
  6. Myelin Basic Protein Induces Neuron-Specific Toxicity by Directly Damaging the Neuronal Plasma Membrane
    Jie Zhang, Xin Sun, Sixin Zheng, Xiao Liu, Jinghua Jin, Yi Ren, Jianhong Luo · 2014 · PLoS ONE
  7. TNF superfamily member TWEAK exacerbates inflammation and demyelination in the cuprizone-induced model
    Heather A. Iocca, Sheila R. Plant, Ying Wang, Laura Runkel, Brian P. O’Connor, Emma T. Lundsmith, Kyungmin Hahm, Hendrik W. van Deventer, Linda C. Burkly, Jenny P.‐Y. Ting · 2008 · Journal of Neuroimmunology
  8. Expression of carbonic anhydrase II mRNA and protein in oligodendrocytes during toxic demyelination in the young adult mouse
    Francine A. Tansey, Hong Zhang, Wendy Cammer · 1996 · Neurochemical Research
  9. Wernicke's encephalopathy
    Nathan K. Blank, Nicholas A. Vick, Sidney Schulman · 1975 · Acta Neuropathologica
  10. Female sex steroids and glia cells: Impact on multiple sclerosis lesion formation and fine tuning of the local neurodegenerative cellular network
    Markus Kipp, Tanja Hochstrasser, Christoph Schmitz, Cordian Beyer · 2015 · Neuroscience & Biobehavioral Reviews
  11. Induction of myelin-associated glycoprotein mRNA in experimental remyelination
    Nobuya Fujita, Hideaki Ishiguro, Shuzo Sato, Tadashi Kurihara, Ryozo Kuwano, Kenji Sakimura, Yasuo Takahashi, Tadashi Miyatake · 1990 · Brain Research
  12. Clinical features of avian vacuolar myelinopathy in American coots
    R. Scott Larsen, Felicia B. Nutter, Tom Augspurger, Tonie E. Rocke, Lindsay Tomlinson, Nancy J. Thomas, Michael K. Stoskopf · 2002 · Journal of the American Veterinary Medical Association
  13. Atypical localization of the oligodendrocytic isoform (PI) of glutathione‐S‐transferase in astrocytes during cuprizone intoxication
    Wendy Cammer, H. Zhang · 1993 · Journal of Neuroscience Research
  14. Hereditary myelopathy of Afghan hounds, a myelinolytic disease
    John F. Cummings, Alexander de Lahunta · 1978 · Acta Neuropathologica
  15. Demyelination in mice resulting from infection with a mutant of Semliki Forest virus
    Brian J. Sheahan, P. N. Barrett, Gerald J. Atkins · 1981 · Acta Neuropathologica
  16. Demyelination in Mice After Two or Three Infections with Avirulent Semliki Forest Virus
    May Chew-Lim, Anthony J. Suckling, H. E. Webb · 1977 · Veterinary Pathology-Supplement
  17. FEAST: A flow cytometry-based toolkit for interrogating microglial engulfment of synaptic and myelin proteins
    Lasse Dissing‐Olesen, Alec J. Walker, Qian Feng, Helena J. Barr, Alicia C. Walker, Lili Xie, Daniel K. Wilton, Indrani Das, Larry I. Benowitz, Beth Stevens · 2023 · Nature Communications
  18. Comparative prion disease gene expression profiling using the prion disease mimetic, cuprizone
    Laura R. Moody, Allen J. Herbst, Han Sang Yoo, Joshua P. Vanderloo, Judd M. Aiken · 2009 · Prion
  19. BIOCHEMICAL STUDIES ON DEGENERATIVE NEUROLOGICAL DISORDERS: 1. ACUTE EXPERIMENTAL ENCEPHALITIS
    David M. Bowen, R. H. A. FLACK, R. O. Martin, Carolyn Beebe Smith, Pamela White, ALAN N. DAVISON · 1974 · Journal of Neurochemistry
  20. Remyelination in animal models of multiple sclerosis: finding the elusive grail of regeneration
    Packer, Davin, Fresenko, Emily E., Harrington, Em P. · 2023 · Frontiers in Molecular Neuroscience
  21. Status spongiosus of rat central nervous system induced by Actinomycin D
    Nicol� Rizzuto, Pierluigi L. Gambetti · 1976 · Acta Neuropathologica
  22. An electron microscopic study of astroglia and oligodendroglia in the lateral geniculate nucleus of aged rats
    Carmen de la Rosa, Josefina Cano, Fernando Reinoso‐Suárez · 1985 · Mechanisms of Ageing and Development
  23. Effect and Mechanism of Catalpol on Remyelination via Regulation of the NOTCH1 Signaling Pathway
    Yaqin Sun, Jing Ji, Zheng Zha, Hui Zhao, Bing Xue, Liang-Yun Jin, Lei Wang · 2021 · Frontiers in Pharmacology
  24. Multiple Sclerosis: Basic and Clinical
    Katherine A. Buzzard, Wing Hei Chan, Trevor John Kilpatrick, Simon S. Murray · 2017 · Advances in neurobiology
  25. Glial fibrillary acidic protein expression alters astrocytic chemokine release and protects mice from cuprizone‐induced demyelination
    Nadine Kramann, Lena Menken, Ramona Pförtner, Susanne N. Schmid, Christine Stadelmann, Christiane Wegner, Wolfgang Brück · 2019 · Glia
  26. Perinatal mortality in lambs of ewes exposed to cultures of Diplodia maydis (= Stenocarpella maydis) during gestation. A study of the central-nervous-system lesions.
    Leon Prozesky, T S Kellerman, Dick Swart, B P Maartens, Ronald Schultz · 1994 · PubMed
  27. Experimental modifications of postnatal differentiation and fate of glial cells related to axo‐glial relationships
    Jean Valat, Alain Privat, Jean Fulcrand · 1988 · International Journal of Developmental Neuroscience
  28. Development, Regeneration, and Neoplasia of Glial Cells in the Central Nervous System
    Mark Noble, Paris Ataliotis, Susan Carol Barnett, Karen Bevan, Oliver Bögler, Andrew K. Groves, Parmjit Jat, Guus Wolswijk, Damian R. Wren · 1991 · Annals of the New York Academy of Sciences
  29. Hexachlorophene and Cuprizone Induce the Spongy Change of the Developing Rat Brain by Different Mechanisms: The Role of 2’, 3’-Cyclic Nucleotide 3’-Phosphodiesterase (CNPase)
    Takeshi Kanno, Satoshi SASAKI, Naoaki YAMADA, Kazufumi Kawasako, Minoru Tsuchitani · 2012 · Journal of Veterinary Medical Science
  30. Alterations of oligodendrocytes and demyelination in the spinal cord of patients with mitochondrial encephalomyopathy
    Shinji Ohara, Eisaku Ohama, Hitoshi Takahashi, Fusahiro Ikuta, Masatoyo Nishizawa, Keiko Tanaka, Tadashi Miyatake · 1988 · Journal of the Neurological Sciences
  31. Oligodendrocyte Development and the Natural History of Multiple Sclerosis
    Stanton B. Elias · 1987 · Archives of Neurology
  32. Direct Lineage Reprogramming in the CNS
    Justine Bajohr, Maryam Faiz · 2019 · Advances in experimental medicine and biology
  33. Pathological changes in mice with long term cuprizone administration
    Taichi Nomura, Yoshio Bandô, Hitomi Nakazawa, Soshi Kanemoto, Shigetaka Yoshida · 2019 · Neurochemistry International
  34. Brain Metabolite Changes in Subcortical Regions After Exposure to Cuprizone for 6 Weeks: Potential Implications for Schizophrenia
    Gen Yan, Yinghua Xuan, Zhuozhi Dai, Zhiwei Shen, Guishan Zhang, Haiyun Xu, Renhua Wu · 2014 · Neurochemical Research
  35. Partial inhibition of proteasome activity enhances remyelination after cuprizone-induced demyelination
    V. Millet, Cristian P. Moiola, Juana Maria Pasquini, Eduardo F. Soto, Laura Andrea Pasquini · 2009 · Experimental Neurology
  36. Creutzfeldt-Jakob disease: Clinical, EEG and neuropathological findings in a cluster of eleven patients
    Alfredo Lechi, Filomeno Tedeschi, D. Mancia, Vladimiro Pietrini, Fabrizio Tagliavini, M. G. Terzano, Gianriccardo Trabattoni · 1983 · Neurological Sciences
  37. Remyelination by Endogenous Glia
    Robin J.M. Franklin, James E. Goldman · 2004 · Elsevier eBooks
  38. Experimental autoimmune encephalomyelitis from a tissue energy perspective
    Roshni A. Desai, Kenneth J. Smith · 2017 · F1000Research
  39. Molecular modeling on human CCR5 receptors and complex with CD4 antigens and HIV-1 envelope glycoprotein gp120.
    J Yang, C Q Liu · 2000 · PubMed
  40. A primary demyelinating disorder of young cattle
    A. C. Palmer, Paul Jackson, William F. Blakemore · 1991 · Neuropathology and Applied Neurobiology
  41. The effects of cuprizone toxicity on the incubation period of scrapie in mice
    R.H. Kimberlin, G.G. Millson · 1976 · Journal of Comparative Pathology
  42. Ultrastructural findings in spongy degeneration of white matter in silver foxes (Vulpes vulpes)
    G. Hagen, William F. Blakemore, I. Bjerk�s · 1990 · Acta Neuropathologica
  43. Ultrastructural localization of glycogen phosphorylase predominantly in astrocytes of the gerbil brain
    Karin Richter, Bernd Hamprecht, Henning Scheich · 1996 · Glia
  44. Dysmyelination in Jimpy mouse due to astroglial hyperplasia?
    Claus Meier, Albert Bischoff · 1977 · Nature
  45. Roads to Formation of Normal Myelin Structure and Pathological Myelin Structure
    Yoshio Bandô · 2019 · Advances in experimental medicine and biology
  46. Pericytes in Multiple Sclerosis
    Francisco J. Rivera, Bryan Hinrichsen, Maria Elena Silva · 2019 · Advances in experimental medicine and biology
  47. Hyperbaric oxygen for patients with multiple sclerosis.
    Jürgen Mertin, W. I. McDonald · 1984 · BMJ
  48. Autofluorescence spectroscopy as a proxy for chronic white matter pathology
    Megan L. Morgan, Deepak K Kaushik, Peter K. Stys, Andrew V. Caprariello · 2020 · Multiple Sclerosis Journal
  49. Rapid upregulation of the Pi isoform of glutathione-S-transferase in mouse brains after withdrawal of the neurotoxicant, cuprizone
    Francine A. Tansey, Hong Zhang, Wendy Cammer · 1997 · Molecular and Chemical Neuropathology
  50. Chemically Induced Myelinopathies
    Marcia van Gemert, James P. Killeen · 1998 · International Journal of Toxicology
  51. Possible role of toxins in nutritional deficiency
    Allan D. Thomson, M D Jeyasingham, OLIVER E. PRATT · 1987 · American Journal of Clinical Nutrition
  52. Siponimod supports remyelination in the non-supportive environment
    Johann Krüger, Newshan Behrangi, David Schliep, Leo Heinig, Elise Vankriekelsvenne, Nicole Wigger, Markus Kipp · 2025 · Scientific Reports
  53. In vitro studies on the comparative sensitivities of cells of the central nervous system to diphtheria toxin
    Kerren Murray, Mark Noble · 1985 · Journal of the Neurological Sciences
  54. Abcd1 deficiency accelerates cuprizone-induced oligodendrocyte loss and axonopathy in a demyelinating mouse model of X-linked adrenoleukodystrophy
    Ksenija Martinović, Jan Bauer, Markus Kunze, Johannes Berger, Sonja Forss‐Petter · 2023 · Acta Neuropathologica Communications
  55. Laquinimod (ABR-215062) for the treatment of relapsing multiple sclerosis
    Simona E. Constantinescu, Cris S. Constantinescu · 2015 · Expert Review of Clinical Pharmacology
  56. Effect of the hypocholesterolemic drug AY9944 on developing central nervous system of rats: Alteration of endoplasmic reticulum in oligodendroglia
    Kinuko Suzuki, Joy C. Zagoren · 1973 · Journal of Neurocytology
  57. Water-Soluble Cuprizone Derivative: Synthesis, Characterization, and in Vitro Studies
    Martin Fries, Meike Mertens, Nico Teske, Markus Kipp, Cordian Beyer, Thomas Willms, Arto Valkonen, Kari T. Rissanen, Markus Albrecht, Tim Clarner · 2019 · ACS Omega
  58. The CD24-Siglec G axis protects mice against cuprizone-induced oligodendrocyte loss: targeting danger signal for neuroprotection
    Ning Li, Pan Zheng, Yang Liu · 2017 · Cellular and Molecular Immunology
  59. Abnormal ultrastructural appearances in axons of feline pericruciate cortex after lateral funiculotomy
    Kevin D. Barron, Mark P. Dentinger · 1978 · Acta Neuropathologica
  60. Marek's disease virus-induced transient paralysis in chickens: electron microscopic lesions
    Joe N. Kornegay, Edward J. Gorgacz · 1988 · Acta Neuropathologica
  61. Astrocytes: Lessons Learned from the Cuprizone Model
    Markus Kipp · 2023 · International Journal of Molecular Sciences
  62. Rapid and prolonged response of oligodendrocyte lineage cells in standard acute cuprizone demyelination model revealed by in situ hybridization
    Yuehua He, Hua Qiang Xie, Zhengtao Xu, Liuning Zhang, Yuanyu Feng, Yu Long, Shuming Wang, Yongxiang He, Jiong Li, Yanping Zou et al. · 2024 · Neuroscience Letters
  63. GCN2-Mediated eIF2α Phosphorylation Is Required for Central Nervous System Remyelination
    Paulina Falcón, Álvaro Brito, Marcela Escandón, Juan Francisco Roa, Nicolás W. Martínez, Ariel Tapia-Godoy, Pamela Farfán, Soledad Matus · 2025 · International Journal of Molecular Sciences
  64. GLIAL CHANGES IN PIGS WITH PORTO‐CAVAL ANASTOMOSIS AND TEMPORARY OR TOTAL HEPATIC ARTERY CLAMPING
    Nils Henrik Diemer, K. Tønnesen · 1977 · Acta Pathologica Microbiologica Scandinavica Section A Pathology
  65. Atypical glial cells in demyelinated and hypomyelinated mouse brains
    Wendy Cammer, Hong Zhang · 1999 · Brain Research
  66. TOXIC EFFECTS ON THE NODE OF RANVIER
    Jean M. Jacobs · 1984 · Elsevier eBooks
  67. Ursolic acid derivative UAOS-Na treats experimental autoimmune encephalomyelitis by immunoregulation and protecting myelin
    Maolin Wang, Chenming Gu, Yifu Yang, Liang Chen, Kaixian Chen, Jun Bao Du, Huali Wu, Yiming Li · 2023 · Frontiers in Neurology
  68. Temporal Alterations in White Matter in AnAppKnock-In Mouse Model of Alzheimer’s Disease
    Zachery D. Morrissey, Jin Gao, Aashutosh Shetti, Wenping Li, Liang Zhan, Weiguo Li, Igor Fortel, Takaomi C. Saido, Takashi Saito, Olusola Ajilore et al. · 2024 · eNeuro
  69. XIAP protects oligodendrocytes against cell death in vitro but has no functional role in toxic demyelination
    Amke Hesse, Karin Hagemeier, Alexander Lürbke, Jasmin Held, Hana C. Friedman, Alan Peterson, Wolfgang Brück, Tanja Kuhlmann · 2011 · Glia
  70. Scutellarin Alleviates Cuprizone-Induced Demyelination by Improving Mitochondrial Dysfunction, Reducing Lipid Oxidation and Inhibiting the p38 MAPK Pathway
    Qiting Zhao, Yantuanjin Ma, Shufen Wang · 2025 · Antioxidants
  71. PART 2: Mouse models for multiple sclerosis research
    Ramalakshmi Ramasamy, Phillip P. Smith · 2021 · Neurourology and Urodynamics
  72. Microbial Neuraminidase Induces a Moderate and Transient Myelin Vacuolation Independent of Complement System Activation
    Pablo Granados‐Durán, María Dolores López-Ávalos, Manuel Cifuentes, Margarita Pérez‐Martín, María del Mar Fernández‐Arjona, Timothy R. Hughes, Krista K. Johnson, B. Paul Morgan, Pedro Fernández‐Llebrez, Jesús M. Grondona · 2017 · Frontiers in Neurology
  73. Myelin in Normal and Diseased States
    Nicole Baumann, C. Jacque, Jean‐Jacques Hauw · 1983 · Neurologic Clinics
  74. Structural Organisation and Stability of Central Nervous System Myelin
    Martin G. Rumsby · 1987 · Springer eBooks
  75. Investigating the use of cuprizone and lysolecithin to model demyelination ex vivo in sagittal rat brain organotypic slice cultures
    Brooke Hawker, Bronwen J. Connor, Amy McCaughey‐Chapman · 2025 · Frontiers in Cellular Neuroscience
  76. Remyelination in Multiple Sclerosis: The Therapeutic Potential of Neural and Mesenchymal Stem/Progenitor Cells
    Francisco J. Rivera, Jörg Kraus, Carolin Steffenhagen, Patrick Küry, Norbert Weidner, Ludwig Aigner · 2011 · Current Signal Transduction Therapy
  77. An In-Vitro Approach to the Study of Oligodendrocytes and Their Involvement in Multiple Sclerosis
    Sara Szuchet, Marc Dumas · 1983 · Neurologic Clinics
  78. Cuprizone‐mediated demyelination reversibly degrades voiding behavior in mice while sparing brainstem reflex
    Ramalakshmi Ramasamy, Cara C. Hardy, Stephen J. Crocker, Phillip P. Smith · 2022 · Journal of Neuroscience Research
  79. Supplemental study on 2’, 3’-Cyclic Nucleotide 3’-Phosphodiesterase (CNPase) activity in developing rat spinal cord lesions induced by hexachlorophene and cuprizone
    Takeshi Kanno, Tetsuro Kurotaki, Naoaki YAMADA, Yuki Tomonari, Junko Sato, Minoru Tsuchitani, Yoshiyasu KOBAYASHI · 2019 · Journal of Veterinary Medical Science
  80. White Matter Pathophysiology
    Bruce R. Ransom, Mark P. Goldberg, Ken Arai, Selva Baltan · 2015 · Elsevier eBooks
  81. Neuroprotective effect of newly synthesized 4-aminopyridine derivatives on cuprizone-induced demyelination in mice—a behavioral and immunohistochemical study
    Ivanka Kostadinova, Boycho V. Landzhov, Lyubomir Marinov, Lyubomir T. Vezenkov, Nikolai D. Danchev · 2021 · Amino Acids
  82. Effects of recombinant human erythropoietin in the cuprizone mouse model of de- and remyelination
    Nora Hagemeyer · 2012
  83. Spatial transcriptomics reveals heterogeneous cell–cell interactions among brain regions in a cuprizone model consistent with multiple sclerosis lesions
    Hui‐Hsin Tsai, Sarbottam Piya, Jing Wang, Jing Ke Zhu, Wenxing Hu, Andrew R. Gehrke, Shaolong Cao, Amanda J. Guise, Su Jing Chan, Mark J. Sheehan et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  84. Neuropathological Examinations in the Mouse Brain-Investigation of a New Pharmaceutical Target in the Cuprizone Model and Comparative Histological Analyses of Primary Cilia in the Physiological Central Nervous System
    Éva Sipos · 2021
  85. The use of animal models of neuroinflammation for imaging studies
    2023 · Advances in magnetic resonance technology and applications
  86. Chemische Krankheitsursachen und Nervensystem
    Hans H. Berlet, Günter Quadbeck, G�nter Ule · 1983 · Spezielle pathologische Anatomie
  87. Strahlenbiologie des zentralen und peripheren Nervensystems
    E. Röttinger · 1985 · Handbuch der medizinischen Radiologie
  88. Repair Mechanisms in the CNS Following Toxic Injury to Glial Cells
    William F. Blakemore · 1989 · Human Toxicology
  89. Immune mediators of central nervous system demyelination and remyelination
    Vivian S. Chen · 2019 · Carolina Digital Repository (University of North Carolina at Chapel Hill)
  90. Role of microglia in myelin turnover
    Shima Safaiyan · 2016 · MPG.PuRe (Max Planck Society)
  91. Neuropathologie auf zellulärer Ebene
    Asao Hirano · 1983 · Springer eBooks
  92. Myelin basic protein profile of central nervous system in experimentally induced demyelination and remyelination
    Gül Fatma Yarım, Murat Yarım, Gülay Çiftçi, Mehmet Önder Karayığıt · 2013 · Turkish Journal of Biochemistry
  93. イヌのgloboid cell leukodystrophy
    邦夫 矢島 · 1980 · 脳と発達
  94. Reduced astrocytic NF-jB activation by laquinimod protects from cuprizone-induced demyelination Wolfgang BruckRamona PfortnerTrinh PhamJingya ZhangLiat HayardenyVictor Piryatinsky • Uwe-Karsten HanischTommy RegenDenise van RossumLars BrakelmannKarin Hagemeier • Tanja KuhlmannChristine StadelmannGareth R. JohnNadine KramannChristiane Wegner
    Tommy Regen, Christine Stadelmann, Nadine Kramann, Christiane Wegner, Tram Pham, J. Zhang, Gareth R. John, Liat Hayardeny, Victor Piryatinsky, Denise van Rossum et al. · 2012
  95. The role of astrocytes in murine models of toxic demyelination
    Lena Menken · 2016
  96. IN VIVO DIFFUSION WEIGHTED MAGNETIC RESONANCE SPECTROSCOPY IN MULTIPLE SCLEROSIS
    Emily Turner Wood · 2015
  97. Emerging Drugs and Targets for Remyelination in Multiple Sclerosis
    Laura J. Wagstaff, Anna Williams · 2019 · Royal Society of Chemistry eBooks
  98. Sex differences and the protective influence of estrogen in a mouse model of demyelinating disease
    Lorelei C. Taylor · 2019 · Carolina Digital Repository (University of North Carolina at Chapel Hill)
  99. Fractalkine Induces the Expression of Intercellular Adhesion Molecule-1 on CD4+ T-lymphocytes: implications for the immunopathogenesis of Multiple Sclerosis
    Kevin Blauth · 2019 · Carolina Digital Repository (University of North Carolina at Chapel Hill)
  100. The role of the astrocytic and microglial aryl hydrocarbon receptor in CNS demyelination
    Schmid, Susanne · 2020