Cited by 217Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration MechanismsNeurogenesis and neuroplasticity mechanisms

Observations on oligodendrocyte degeneration, the resolution of status spongiosus and remyelination in cuprizone intoxication in mice

Blakemore, W. F.·1972·Journal of Neurocytology

Integrity signals

Registry

Crossref · 10.1007/bf01102943

Cites

31 of 31 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Other mouse strains are also used sometimes in the cuprizone model.

    “However, other strains are also used sometimes [7–10].”

    From Strain differences in cuprizone induced demyelination (2017) · cites this paper as [7]

  • Astrocyte reactivity is associated with increased activity of oxidative enzymes, which may contribute to ROS mediated toxicity.

    “Astrocyte reactivity is associated with increased activity of oxidative enzymes (glutamate dehydrogenase, lactate dehydrogenase, NAD(P)H dehydrogenase, NADH dehydrogenase) [42, 178, 179] which may contribute to ROS mediated toxicity.”
  • After 5-6 weeks of cuprizone exposure, there is complete demyelination of distinct subregions (acute demyelination), paralleled by extensive microglial and astrocytic proliferation and damage to axons.

    “After 5–6 weeks of cuprizone exposure, there is complete demyelination of distinct subregions (called acute demyelination), paralleled by extensive microglial and astrocytic proliferation and damage to axons [22,23,24,25].”

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Authors
Blakemore, W. F.
Affiliations
University of Cambridge (GB)
Corresponding author
Blakemore, W. F.
Venue
Journal of Neurocytology
Published
1972-12
Volume
1
Issue
4
Pages
413-426
ISSN
  • 0300-4864 (ISSN-L)
  • 1573-7381
OpenAlex
W1980249948
Cited by
217
References
31
Citations by year
2026: 2 · 2025: 5 · 2024: 3 · 2023: 11 · 2022: 5 · 2021: 6 · 2020: 5 · 2019: 17 · 2018: 4 · 2017: 8 · 2016: 5 · 2015: 8 · 2014: 4 · 2013: 7 · 2012: 6
FWCI
5.75
Type
journal article
Language
en
Open access
closed
Locations
  • Journal of Neurocytology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Pathology and Forensic Medicine › Multiple Sclerosis Research Studies
  • Life Sciences › Neuroscience › Neurology › Neuroinflammation and Neurodegeneration Mechanisms
  • Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
Keywords
cuprizone, oligodendrocyte degeneration, status spongiosus, remyelination, demyelination, astrocyte activation, microglia, mice
MeSH terms
Animals, Cuprizone, Male, Mice, Inbred Strains, Myelin Sheath, Nerve Degeneration, Oligodendroglia, Prion Diseases, Mice

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review