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The regulation mechanism of c-jun and junB by human papillomavirus type 16 E5 oncoprotein

Chen, S. -L., Huang, C. -H., Tsai, T. -C., Lu, K. -Y., Tsao, Y. -P.·1996·Archives of Virology
DOI 10.1007/bf01718155
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Abstract

In this study, we show that HPV-16 E5 induced anchorage-independent growth in immortalized human epidermal keratinocytes and that HPV-16 E5 in human keratinocytes had higher expression of c-jun and junB; also, we investigated the role of transcriptional initiation pathways in the expression elevation. In addition, Ras-dependent pathway, as well as PKC-dependent pathway, leads to HPV-16 E5-induced c-jun gene expression.

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Citations

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Research works printed but not linked: 31

  1. Angel P, Karin M (1991) The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation. Biochim Biophys Acta 1072: 129–157
  2. Binetruy B, Smeal T, Karin M (1991) Ha-Ras arguments c-Jun activity and stimulates phosphorylation of its activation domain. Nature 351: 122–127 · DOI
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  6. Chen SL, Tsao LT, Tsao YP (1994) Antisense oligodeoxynucleotides to c-jun inhibits proliferation of transformed NIH 3T3 cells induced by E5a of HPV-11. Cancer Lett 85: 119–123 · DOI
  7. Chen SL, Tsao YP, Yang CM, Lin YK, Huang CH, Kuo SW (1995) Differential induction and regulation of c-jun, junB, junD and c-fos by human papillomavirus type 11 E5a oncoprotein. J Gen Virol 76: 2653–2659 · DOI
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Metadata

Authors
Chen, S. L., Huang, C. H., Tsai, T. C., Lu, K. Y., & Tsao, Y. P.
Venue
Archives of Virology
Publisher
Springer Science and Business Media LLC
Published
1996-05
Volume
141
Issue
5
Pages
791-800
ISSN
  • 0304-8608
  • 1432-8798
DOI
10.1007/bf01718155
Cited by
30
References
0
Language
en
Licence
www.springer.com/tdm (tdm)

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CoChat. (2026). Citation check: The regulation mechanism of c-jun and junB by human papillomavirus type 16 E5 oncoprotein. https://app.cochat.ai/papers/10.1007/bf01718155
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Chen, S. L., Huang, C. H., Tsai, T. C., Lu, K. Y., & Tsao, Y. P. (1996). The regulation mechanism of c-jun and junB by human papillomavirus type 16 E5 oncoprotein. Archives of Virology. https://doi.org/10.1007/bf01718155