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Cited by 615

The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.

Pre‐operative radiotherapy prolongs survival in operable esophageal carcinoma: A randomized, multicenter study of pre‐operative radiotherapy and chemotherapy. The second scandinavian trial in esophageal cancer

Nygaard, Knut, Hagen, Steinar, Hansen, Hanne Sand, Hatlevoll, Reidulv, Hultborn, Ragnar, Jakobsen, Anders, Mäntyla, Matti, Modig, Hans, Munck‐Wikland, Eva, Rosengren, Bengt, Tausjø, Johan, Elgen, Kjell·1992·World Journal of Surgery

Abstract

In a prospective multicenter study, 186 patients with squamous cell esophageal carcinoma, who after evaluation were considered suitable for surgery, were randomized to 4 treatment groups: Group 1, surgery alone; Group 2, pre‐operative chemotherapy (cisplatin and bleomycin) and surgery; Group 3, pre‐operative irradiation (35 Gy) and surgery; Group 4, pre‐operative chemotherapy, radiotherapy, and surgery. Three‐year survival was significantly higher in the pooled groups receiving radiotherapy as compared with the pooled groups not receiving radiotherapy. Comparison of the groups having pre‐operative chemotherapy with those not having chemotherapy showed no significant difference in survival. Female patients had a significantly better survival than males. The results indicate that pre‐operative irradiation had a beneficial effect on intermediate term survival, whereas the chemotherapy regime used did not influence survival.

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Crossref · 10.1007/bf02067069

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Metadata

Authors
Nygaard, K., Hagen, S., Hansen, H. S., Hatlevoll, R., Hultborn, R., Jakobsen, A., Mäntyla, M., Modig, H., Munck‐Wikland, E., Rosengren, B., Tausjø, J., & Elgen, K.
Venue
World Journal of Surgery
Publisher
Wiley
Published
1992-11
Volume
16
Issue
6
Pages
1104-1109
ISSN
  • 0364-2313 (ISSN-L)
  • 1432-2323
OpenAlex
W2029081428
Cited by
615
References
9
FWCI
6.45
Type
journal article
Language
en
Open access
closed

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