Health-related quality of life of patients with acute erosive reflux esophagitis
Abstract
One thousand one hundred forty-five patients with acute erosive reflux esophagitis participating in an eight-week double-blind, multicenter study of lansoprazole 15 mg daily, lansoprazole 30 mg daily, omeprazole 20 mg daily, and placebo responded to a health-related quality of life (HRQoL) questionnaire at baseline and at two, four, and eight weeks. At baseline, there were no HRQoL differences among the four study groups. However, all three active treatment groups improved statistically significantly more than placebo on most HRQoL scales at each follow-up. There were no statistically significant differences among the three active treatment groups at week 2, although in most instances lansoprazole 30 mg showed slightly more improvement. After week 2, benefits in all the study groups leveled off and remained constant. Greater acid suppression appeared to result in greater improvement in terms of HRQoL.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Painful, chronic endometriosis symptoms are known to cause poor quality of life in many patients.
“The painful, chronic symptoms of endometriosis are known to result in poor quality of life (QoL) in a substantial number of patients (12-15).”
From Quantification of the impact of endometriosis symptoms on health-related quality of life and work productivity (2011) · cites this paper as [15]
Cites
SF-36 health survey: Manual and interpretation guide
Ware, J. (2003) · Medical Entomology and Zoology · Cited by 11,424 · see citing works
Measuring Functioning and Well-Being: The Medical Outcomes Study Approach
Stewart, A., & Ware, J. (1992) · doi:10.7249/cb361 · Cited by 2,689 · see citing works
Stewart, A. L. (1989) · JAMA · doi:10.1001/jama.262.7.907 · Cited by 2,095 · see citing works
Generic and Disease-Specific Measures in Assessing Health Status and Quality of Life
Patrick, D. L., & Deyo, R. A. (1989) · Medical Care · doi:10.1097/00005650-198903001-00018 · Cited by 1,779 · see citing works
Functional Status and Well-being of Patients With Chronic Conditions
Stewart, A. L. (1989) · JAMA · doi:10.1001/jama.1989.03430070055030 · Cited by 1,741 · see citing works
Dimenäs, E., Glise, H., Hallerbäck, B., Hernqvist, H., Svedlund, J., & Wiklund, I. E. (1993) · Scandinavian Journal of Gastroenterology · doi:10.3109/00365529309098272 · Cited by 422 · see citing works
McGee, H. M., O’Boyle, C. A., Hickey, A., O’Malley, K., & Joyce, C. R. B. (1991) · Psychological Medicine · doi:10.1017/s0033291700022388 · Cited by 321 · see citing works
Sontag, S. J., Hirschowitz, B. I., Holt, S., ROBINSON, M. G., Behar, J., Berenson, M. M., McCullough, A. J., Ippoliti, A., Richter, J. E., Ahtaridis, G., et al. (1992) · Gastroenterology · doi:10.1016/0016-5085(92)91790-b · Cited by 168 · see citing works
Mathias, S. D., Fifer, S., Mazonson, P. D., Lubeck, D., Buesching, D., & Patrick, D. L. (1994) · Journal of general internal medicine · doi:10.1007/bf02600303 · Cited by 153 · see citing works
Self-citationHealth-related quality of life in the evaluation of medical therapy for chronic illness.
Revicki, D. A. (1989) · PubMed · Cited by 102 · see citing works
Rush, D. R., Wj, S., Young, T. L., Kirchdoerfer, L. J., Scott-Lennox, J. A., Holverson, H. E., Sabesin, S. M., & Nicholas, T. A. (1995) · PubMed · Cited by 73 · see citing works
Current Diagnosis and Treatment of Gastroesophageal Reflux Disease
de Vault, K., & Castell, D. O. (1994) · Mayo Clinic Proceedings · doi:10.1016/s0025-6196(12)61790-x · Cited by 71 · see citing works
Self-citationFunctional Status Measurement in Primary Care
(1991) · Annals of Internal Medicine · doi:10.7326/0003-4819-114-7-609_4 · Cited by 58 · see citing works
Quality of Life Instruments in the Evaluation of New Drugs
Jaeschke, R., Guyatt, G. H., & Cook, D. (1992) · PharmacoEconomics · doi:10.2165/00019053-199201020-00004 · Cited by 49 · see citing works
Psychometric Considerations in Functional Status Instruments
Stewart, A. L. (1990) · Frontiers of primary care · doi:10.1007/978-1-4613-8977-4_1 · Cited by 41 · see citing works
Chal, K. L., Stacey, J. H., & Sacks, G. (1995) · International Journal of Clinical Practice · doi:10.1111/j.1742-1241.1995.tb09898.x · Cited by 33 · see citing works
Quality of Life Assessments in Patients with Peptic Ulcer During Treatment and Follow-up
Glise, H. (1993) · Scandinavian Journal of Gastroenterology · doi:10.3109/00365529309098354 · Cited by 18 · see citing works
Assessment of Quality of Life Among Patients with Suspected Duodenal Ulcer
Hallerbück, B. (1993) · Scandinavian Journal of Gastroenterology · doi:10.3109/00365529309098353 · Cited by 17 · see citing works
Gastric pH levels after 15 MG and 30 MG of lansoprazole and 20 MG omeprazole
Tolman, K., Sanders, & Buchi, S. W. (1994) · Medicina Moderna - Modern Medicine · Cited by 16 · see citing works
Efficacy, Safety, and Cost Issues in Managing Patients with Gastroesophageal Reflux Disease
Garnett, W. R. (1993) · American Journal of Health-System Pharmacy · doi:10.1093/ajhp/50.4_suppl_1.s11 · Cited by 14 · see citing works
Treatment of gastroesophageal (acid) reflux with lansoprazole: an overview.
Dobrilla, G., & Fede, F. D. (1993) · PubMed · Cited by 14 · see citing works
Clinical and Economic Factors in the Selection of Drugs for Gastroesophageal Reflux Disease
Bate, C. M., & Richardson, P. D. I. (1993) · PharmacoEconomics · doi:10.2165/00019053-199303020-00002 · Cited by 13 · see citing works
Quality of Life in Duodenal Ulcer
Korman, M. G. (1993) · Scandinavian Journal of Gastroenterology · doi:10.3109/00365529309098352 · Cited by 13 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Initial validation of a diagnostic questionnaire for gastroesophageal reflux disease
Shaw, M. J., Talley, N. J., Beebe, T. J., Rockwood, T. H., Carlsson, R., Adlis, S. A., Fendrick, A. M., Jones, R. H., Dent, J., & Bytzer, P. M. (2001) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2001.03451.x · Cited by 403 · see citing works
Fourquet, J., Báez, L., Figueroa, M., Iriarte, R. I., & Flores, I. (2011) · Fertility and Sterility · doi:10.1016/j.fertnstert.2011.04.095 · Cited by 262 · see citing works
“The painful, chronic symptoms of endometriosis are known to result in poor quality of life (QoL) in a substantial number of patients (12-15).”
BackgroundWelage, L. S., & Berardi, R. R. (2000) · Journal of the American Pharmaceutical Association (1996) · doi:10.1016/s1086-5802(16)31036-1 · Cited by 149 · see citing works
Symptoms Associated with Gastroesophageal Reflux Disease
Rothman, M. L., Farup, C. E., Stewart, W., Helbers, L., & Zeldis, J. B. (2001) · Digestive Diseases and Sciences · doi:10.1023/a:1010660425522 · Cited by 112 · see citing works
Do we need a new gastro‐oesophageal reflux disease questionnaire?
Stanghellini, V., Armstrong, D., Mönnikes, H., & Bardhan, K. D. (2004) · Alimentary Pharmacology & Therapeutics · doi:10.1046/j.1365-2036.2004.01861.x · Cited by 104 · see citing works
Epidemiology and natural history of reflux disease
Nandurkar, S., & Talley, N. J. (2000) · Best Practice & Research Clinical Gastroenterology · doi:10.1053/bega.2000.0122 · Cited by 102 · see citing works
Pace, F., Bollani, S., Molteni, P., & Porro, G. B. (2003) · Digestive and Liver Disease · doi:10.1016/j.dld.2003.10.012 · Cited by 80 · see citing works
Symptom-Based Outcome Measures for Dyspepsia and GERD Trials: A Systematic Review
Fraser, A., Delaney, B. C., & Moayyedi, P. (2005) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2005.40122.x · Cited by 69 · see citing works
Damiano, A. M., Handley, K., Adler, E., Siddique, R. M., & Bhattacharyja, A. (2002) · Digestive Diseases and Sciences · doi:10.1023/a:1015815102175 · Cited by 60 · see citing works
pH, healing rate, and symptom relief in patients with GERD.
Huang, J. Q., & Hunt, R. H. (1999) · PubMed Central · Cited by 60 · see citing works
Rentz, A. M., Battista, C., Trudeau, E., Jones, R., Robinson, P., Sloan, S., Mathur, S., Frank, L. B., & Revicki, D. A. (2001) · PharmacoEconomics · doi:10.2165/00019053-200119040-00003 · Cited by 50 · see citing works
The impact of gastroesophageal reflux disease on quality of life
Kamolz, T., Pointner, R., & Velanovich, V. (2003) · Surgical Endoscopy · doi:10.1007/s00464-002-9229-4 · Cited by 49 · see citing works
Mathias, S. D., Colwell, H. H., Miller, D. P., Pasta, D. J., Henning, J. M., & Ofman, J. J. (2001) · Digestive Diseases and Sciences · doi:10.1023/a:1012363501101 · Cited by 48 · see citing works
Self-citationMeasuring Health-Related Quality of Life in Patients with Upper Gastrointestinal Disease
Moyer, C. A., & Fendrick, A. M. (1998) · Digestive Diseases · doi:10.1159/000016881 · Cited by 47 · see citing works
Colwell, H. H., Mathias, S. D., Pasta, D. J., Henning, J. M., & Hunt, R. H. (1999) · Digestive Diseases and Sciences · doi:10.1023/a:1026647701477 · Cited by 45 · see citing works
Self-citationChassany, O., Holtmann, G., Malagelada, J., GEBAUER, U., Doerfler, H., & DeVault, K. R. (2008) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2008.03683.x · Cited by 41 · see citing works
Nelson, W. W., Vermeulen, L. C., Geurkink, E. A., Ehlert, D. A., & Reichelderfer, M. (2000) · Archives of Internal Medicine · doi:10.1001/archinte.160.16.2491 · Cited by 41 · see citing works
Quality of Life and Severity of Symptoms in Gastro-Oesophageal Reflux Disease: a Clinical Review
Velanovich, V. (2000) · The European Journal of Surgery · doi:10.1080/110241500750008565 · Cited by 41 · see citing works
Questionnaire based gastroesophageal reflux disease (GERD) assessment scales
Mouli, V. P., & Ahuja, V. (2011) · Indian Journal of Gastroenterology · doi:10.1007/s12664-011-0105-9 · Cited by 40 · see citing works
Update on health-related quality of life in patients with gastroesophageal reflux disease
Wiklund, I. E., & Talley, N. J. (2003) · Expert Review of Pharmacoeconomics & Outcomes Research · doi:10.1586/14737167.3.3.341 · Cited by 37 · see citing works
Systematic Review: Do We Need a New Gastro-Oesophageal Reflux Disease Questionnaire?
Stanghellini, V., Armstrong, D., Mönnikes, H., & Bardhan, K. D. (2007) · Digestion · doi:10.1159/000101077 · Cited by 29 · see citing works
Pantoprazole Rapidly Improves Health-Related Quality of Life in Patients With Heartburn
Paré, P., Armstrong, D., Pericak, D., & Pyzyk, M. (2003) · Journal of Clinical Gastroenterology · doi:10.1097/00004836-200308000-00008 · Cited by 26 · see citing works
Joseph, B., Prasanth, C. S., Baiju, K. V., Presanthila, J., & Subhash, N. (2016) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2016.01.004 · Cited by 21 · see citing works
Johanson, J. F., Siddique, R. M., Damiano, A. M., Jokubaitis, L. A., Murthy, A. K., & Bhattacharjya, A. S. (2002) · Digestive Diseases and Sciences · doi:10.1023/a:1020532714664 · Cited by 20 · see citing works
Lansoprazole for Maintenance of Remission of Erosive Oesophagitis
Freston, J. W., Jackson, R. L., Huang, B., & Ballard, E. D. (2002) · Drugs · doi:10.2165/00003495-200262080-00004 · Cited by 18 · see citing works
Modlin, I. M., Malfertheiner, P., Hunt, R. H., Armstrong, D., Holtmann, G., Quigley, E. M., & Spechler, S. J. (2007) · Journal of Clinical Gastroenterology · doi:10.1097/01.mcg.0000225693.69745.49 · Cited by 11 · see citing works
Improving Health-Related Quality of Life in Gastro-Oesophageal Reflux Disease
Shaw, M. J., & Crawley, J. A. (2003) · Drugs · doi:10.2165/00003495-200363210-00003 · Cited by 10 · see citing works
Kovacs, T. O. G., Freston, J. W., Haber, M. M., Atkinson, S. N., Hunt, B., & Peura, D. A. (2009) · Digestive Diseases and Sciences · doi:10.1007/s10620-009-0871-8 · Cited by 9 · see citing works
Kamolz, T., & Velanovich, V. (2006) · Springer eBooks · doi:10.1007/3-211-32317-1_26 · Cited by 8 · see citing works
Long-Term Efficacy of Lansoprazole in Preventing Relapse of Erosive Reflux Esophagitis
Kovacs, T. O. G., Freston, J. W., Haber, M. M., Hunt, B., Atkinson, S. N., & Peura, D. A. (2009) · Digestive Diseases and Sciences · doi:10.1007/s10620-009-0769-5 · Cited by 8 · see citing works
Gastroesophageal Reflux Disease
Chiba, N. (2004) · doi:10.1002/9780470987025.ch2 · Cited by 6 · see citing works
Improving opportunities for effective management of gastro-oesophageal reflux disease
Vigneri, S. (2001) · Digestive and Liver Disease · doi:10.1016/s1590-8658(01)80051-7 · Cited by 5 · see citing works
A Practical Approach to Heartburn
Castell, D. O., & Greenberger, N. J. (1999) · Hospital Practice · doi:10.3810/hp.1999.11.172 · Cited by 5 · see citing works
Self-citationGERD: Management Algorithms for the Primary Care Physician and the Specialist A SPECIAL ARTICLE
Castell, D. O., Brunton, S., Earnest, D. L., Fogel, R., Hinder, R. A., Liss, D., Peters, J. H., & Siegel, M. M. (1999) · Cited by 5 · see citing works
Self-citationTypical and Atypical Manifestations of Gastroesophageal Reflux Disease
Castell, D. O. (1999) · Springer eBooks · doi:10.1007/978-1-4615-4803-4_12 · Cited by 3 · see citing works
Self-citationQuality of life and cost-effectiveness of combined therapy for reflux esophagitis
Si, J., Wang, L., Shu-jie, C., Zhao, L., & Dai, N. (2003) · Journal of Zhejiang University. Science A · doi:10.1631/jzus.2003.0602 · Cited by 2 · see citing works
Gastroesophageal Reflux Disease
Chiba, N., & Fennerty, M. B. (2010) · doi:10.1002/9781444314403.ch2 · Cited by 2 · see citing works
Therapeutic Approaches to Gastroesophageal Reflux Disease
Berard, R. R. (1998) · Journal of Pharmaceutical Care in Pain & Symptom Control · doi:10.1300/j088v06n01_04 · Cited by 1 · see citing works
QUALITY OF LIFE AFTER ANTIREFLUX SURGERY
Lundell, L. R. (2008) · Elsevier eBooks · doi:10.1016/b978-0-443-06861-4.50185-4 · Cited by 1 · see citing works
- Authors
- Mathias, S. D., Castell, D. O., Elkin, E. P., & Matosian, M. L.
- Affiliations
- Graduate Hospital (US)
- ORCID
- Mathias, Susan D.
- Venue
- Digestive Diseases and Sciences
- Published
- 1996-11
- Volume
- 41
- Issue
- 11
- Pages
- 2123-2129
- ISSN
- 0163-2116 (ISSN-L)
- 1573-2568
- OpenAlex
- W2027677946
- Cited by
- 39
- References
- 23
- Citations by year
- 2016: 1
- FWCI
- 2.84
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Digestive Diseases and Sciences (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Gastroenterology › Gastroesophageal reflux and treatments
- Health Sciences › Dentistry › Orthodontics › Dental Erosion and Treatment
- Health Sciences › Medicine › Surgery › Helicobacter pylori-related gastroenterology studies
- Keywords
- health-related quality of life, erosive reflux esophagitis, lansoprazole, omeprazole, proton pump inhibitors, acid suppression, gastroesophageal reflux disease, placebo comparison
- MeSH terms
- Acute Disease, Analysis of Variance, Double-Blind Method, Enzyme Inhibitors, Esophagitis, Peptic, Female, Humans, Male, Middle Aged, Omeprazole, Quality of Life, Surveys and Questionnaires, Reproducibility of Results, 2-Pyridinylmethylsulfinylbenzimidazoles, Proton Pump Inhibitors, Lansoprazole
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
