A health-related quality of life measure for multiple sclerosis

Vickrey, B. G., Hays, R. D., Harooni, R., Myers, L. W., Ellison, G. W.·1995·Quality of Life Research

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Items 101–200 of 1,001

  1. Clinical appropriateness: a key factor in outcome measure selection: the 36 item short form health survey in multiple sclerosis
    Jennifer A. Freeman · 2000 · Journal of Neurology Neurosurgery & Psychiatry
  2. Dimethyl fumarate for multiple sclerosis
    Xu Zhu, Feng Zhang, Fangli Sun, KeFeng Gu, Shuai Dong, Dian He · 2015 · Cochrane Database of Systematic Reviews
  3. Vitamin D for the management of multiple sclerosis
    Vanitha A Jagannath, Zbys Fedorowicz, Govindaraj Vaithinathan Asokan, Edward W Robak, Liz Whamond · 2010 · Cochrane Database of Systematic Reviews
  4. Spasticity in patients with multiple sclerosis - clinical characteristics, treatment and quality of life
    Peter Flachenecker, Thomas Henze, Uwe Klaus Zettl · 2013 · Acta Neurologica Scandinavica
  5. Lesion remyelinating activity of GSK239512 versus placebo in patients with relapsing-remitting multiple sclerosis: a randomised, single-blind, phase II study
    Caryl J. Schwartzbach, Richard A. Grove, Robert A. Brown, Debra J. Tompson, Florian Then Bergh, Douglas Lorne Arnold · 2016 · Journal of Neurology
  6. Achieving patient engagement in multiple sclerosis: A perspective from the multiple sclerosis in the 21st Century Steering Group
    Peter Rieckmann, Alexey Boyко, Diego Centonze, Irina Elovaara, Gavin Giovannoni, Eva Havrdová, Otto R. Hommes, Jürg Kesselring, Gisela Kobelt, Dawn Wendy Langdon et al. · 2015 · Multiple Sclerosis and Related Disorders
  7. Quality of life in patients with multiple sclerosis
    Altınay Göksel Karatepe, Taciser Kaya, Rezzan Günaydn, Aylin Demirhan, Plnar Çe, Muhteşem Gedizlioğlu · 2011 · International Journal of Rehabilitation Research
  8. Treatment of multiple sclerosis with interferon beta : an appraisal of cost-effectiveness and quality of life
    D. Parkin · 2000 · Journal of Neurology Neurosurgery & Psychiatry
  9. Deterioration in the health-related quality of life of persons with multiple sclerosis: the possible warning signs
    Karen V. L. Turpin, Linda Carroll, John David Cassidy, Walter J Hader · 2007 · Multiple Sclerosis Journal
  10. Quality of Life Assessment in Multiple Sclerosis: Different Perception between Patients and Neurologists
    María Célica Ysrraelit, Marcela Paula Fiol, María Inés Gaitán, Jorge Daniel Correale · 2018 · Frontiers in Neurology
  11. Major Depression and Quality of Life in Individuals with Multiple Sclerosis
    Jian-Li Wang, M. Reimer, L. Metz, S. Patten · 2000 · International Journal of Psychiatry in Medicine
  12. The relationship among depression, subjective cognitive impairment, and neuropsychological performance in multiple sclerosis
    Laura J. Julian, Natalia Merluzzi, David C. Mohr · 2007 · Multiple Sclerosis Journal
  13. Prevalence of tremor in multiple sclerosis and associated disability in the Olmsted County population
    Sean Joseph Pittock, Robyn L. McClelland, William T. Mayr, Moses Rodriguez, Joseph Y. Matsumoto · 2004 · Movement Disorders
  14. Pilot study exploring quality of life and barriers to leisure-time physical activity in persons with moderate to severe multiple sclerosis
    Elizabeth A. Vanner, Pamela Block, Christopher Christodoulou, Beverly P. Horowitz, Lauren Krupp · 2008 · Disability and health journal
  15. Measuring the Quality of Life in Patients with Multiple Sclerosis in Clinical Practice: A Necessary Challenge
    Karine Baumstarck, Laurent Boyer, Mohamed Boucékine, Pierre Michel, Jean Pelletier, Pascal Auquier · 2013 · Multiple Sclerosis International
  16. Randomized-controlled trial of a modified Mediterranean dietary program for multiple sclerosis: A pilot study
    Ilana Katz Sand, Emma K. T. Benn, Michelle T. Fabian, Kathryn C. Fitzgerald, Elise Digga, Richa Deshpande, Aaron Miller, Samantha Gallo, Lenore Arab · 2019 · Multiple Sclerosis and Related Disorders
  17. The chronic cerebrospinal venous insufficiency syndrome
    Paolo Zamboni, Roberto Galeotti · 2010 · Phlebology The Journal of Venous Disease
  18. Cross-cultural adaptation and validation of multiple sclerosis quality of life questionnaire (MSQOL-54) in a Turkish multiple sclerosis sample
    Egemen İdıman, Fatma Uzunel, Serkan Özakbaş, Nuray Yozbatıran, Meral Oguz, Belgin Callioglu, Nazan Gokce, Zühal Bahar · 2005 · Journal of the Neurological Sciences
  19. Understanding Changes in Health Status
    David W. Baker, Ron D. Hays, Robert Henry Brook · 1997 · Medical Care
  20. Tolerogenic dendritic cell-based treatment for multiple sclerosis (MS): a harmonised study protocol for two phase I clinical trials comparing intradermal and intranodal cell administration
    Barbara M. P. Willekens, Silvia Presas‐Rodríguez, María José Mansilla, Judith Derdelinckx, Wai-Ping Lee, Griet Nijs, Maxime De Laere, Inez Wens, Patrick P Cras, Paul Maria Parizel et al. · 2019 · BMJ Open
  21. MRI T2 hypointensity of the dentate nucleus is related to ambulatory impairment in multiple sclerosis
    Christopher W. Tjoa, Ralph H. B. Benedict, Bianca Weinstock‐Guttman, Andrew J. Fabiano, Rohit Bakshi · 2005 · Journal of the Neurological Sciences
  22. Pathophysiology and management of bowel dysfunction in multiple sclerosis
    Wiesel, Paul H., Norton, Christine, Glickman, Scott, Kamm, Michael A. · 2001 · European Journal of Gastroenterology & Hepatology
  23. Retinal and Optic Nerve Degeneration in Patients with Multiple Sclerosis Followed up for 5 Years
    Elena García‐Martín, J.R. Ara, Jesús Martín, Carmen Almárcegui, Isabel Dolz, Elisa Viladés, Laura Gil‐Arribas, Francisco Javier Fernández Fernández, Vicente Polo, José Manuel Larrosa et al. · 2017 · Ophthalmology
  24. Home-based physical telerehabilitation in patients with multiple sclerosis: a pilot study.
    Joseph Finkelstein, Oleg Lapshin, Heather K. Castro, Eunme Cha, Patricia Geise Provance · 2008 · The Journal of Rehabilitation Research and Development
  25. Correlations between multiple sclerosis functional composite, expanded disability status scale and health-related quality of life during and after treatment of relapses in patients with multiple sclerosis
    Serkan Özakbaş, I. Cagiran, Burcu Örmeci, Egemen İdıman · 2003 · Journal of the Neurological Sciences
  26. “Sticking Jewels in Your Life”: Exploring Women's Strategies for Negotiating an Acceptable Quality of Life with Multiple Sclerosis
    Frances Ann Reynolds, Sarah Jane Prior · 2003 · Qualitative Health Research
  27. Illness perception and health-related quality of life in multiple sclerosis.
    Spain, L. A., Tubridy, N., Kilpatrick, T. J., Adams, S. J., Holmes, A. C. N. · 2007 · Acta Neurologica Scandinavica
  28. Endocrine and immune substrates of depressive symptoms and fatigue in multiple sclerosis patients with comorbid major depression
    Stefan Michael Gold, S. Kruger, Kristin J. Ziegler, Thorsten Krieger, Karl‐Heinz Schulz, Christian Otte, Christoph Heesen · 2011 · Journal of Neurology Neurosurgery & Psychiatry
  29. Pragmatic intervention for increasing self-directed exercise behaviour and improving important health outcomes in people with multiple sclerosis: a randomised controlled trial
    Anouska Carter, Amanda Daley, Liam John Humphreys, Nicky Snowdon, M. Nicola Woodroofe, J Petty, Andrea K. Roalfe, Jonathan C. Tosh, Basil Sharrack, John Saxton · 2014 · Multiple Sclerosis Journal
  30. Health-Related Quality of Life in Multiple Sclerosis
    Richard A. Rudick, Deborah M. Miller · 2008 · CNS Drugs
  31. Quality of life measures for the palliative care of people severely affected by multiple sclerosis: a systematic review
    David A. Gruenewald, Irene J Higginson, Bella Vivat, P Edmonds, Rachel Burman · 2004 · Multiple Sclerosis Journal
  32. Sexual function in multiple sclerosis and associations with demographic, disease and lifestyle characteristics: an international cross-sectional study
    Claudia H. Marck, Pia L. Jelinek, Tracey Joy Weiland, Jane Simone Hocking, Alysha Madhu De Livera, Keryn Louise Taylor, Sandra Leanne Neate, Naresh G. Pereira, George Alexander Jelinek · 2016 · BMC Neurology
  33. Prospective phase II clinical trial of autologous haematopoietic stem cell transplant for treatment refractory multiple sclerosis
    John J. Moore, Jennifer C. Massey, Carole Ford, Melissa L. M. Khoo, John James Zaunders, Kevin Hendrawan, Yael Barnett, Michael Harry Barnett, Kain Kyle, Robert Zivadinov et al. · 2018 · Journal of Neurology Neurosurgery & Psychiatry
  34. Dietary interventions for multiple sclerosis-related outcomes
    Natalie E. Parks, Caitlin S. Jackson-Tarlton, Laura Vacchi, Roah A. Merdad, Bradley C. Johnston · 2020 · Cochrane Database of Systematic Reviews
  35. Rasch analysis of the Multiple Sclerosis Impact Scale (MSIS-29)
    Melina Ramp, Fary Khan, RoseAnne Misajon, Julie Pallant · 2009 · Health and Quality of Life Outcomes
  36. Associations Between Fatigue and Disability, Functional Mobility, Depression, and Quality of Life in People with Multiple Sclerosis
    Hina Garg, Steffani Bush, Eduard Gappmaier · 2015 · International Journal of MS Care
  37. Role of health-related quality of life measures in the routine care of people with multiple sclerosis
    Alessandra Solari · 2005 · Health and Quality of Life Outcomes
  38. Exploring differences between subgroups of multiple sclerosis patients in health-related quality of life
    Lilian E. M. A. Pfennings, Leo Cohen, Herman J. Adèr, Chris H. Polman, Gustaaf J. Lankhorst, Rob A.M.M. Smits, Henk M. van der Ploeg · 1999 · Journal of Neurology
  39. Physical activity and associated levels of disability and quality of life in people with multiple sclerosis: a large international survey
    Claudia H. Marck, Emily J. Hadgkiss, Tracey Joy Weiland, Dania M. van der Meer, Naresh G. Pereira, George Alexander Jelinek · 2014 · BMC Neurology
  40. Relationship between Sensory Processing and Quality of Life: A Systematic Review
    Borja Costa-López, Rosario Ferrer‐Cascales, Nicolás Ruiz‐Robledillo, Natalia Albaladejo-Blázquez, Monika Baryła‐Matejczuk · 2021 · Journal of Clinical Medicine
  41. Evidence-based measurement in multiple sclerosis: the psychometric properties of the physical and psychological dimensions of three quality of life rating scales
    Afsane Riazi, Jeremy Charles Hobart, Donna L. Lamping, Ray M. Fitzpatrick, Alan J. Thompson · 2003 · Multiple Sclerosis Journal
  42. Randomized control trial evaluation of a modified Paleolithic dietary intervention in the treatment of relapsing-remitting multiple sclerosis: a pilot study
    Amanda K. Irish, Constance Erickson, Terry L. Wahls, Linda G. Snetselaar, Warren G. Darling · 2017 · Degenerative Neurological and Neuromuscular Disease
  43. Methodology of an International Study of People with Multiple Sclerosis Recruited through Web 2.0 Platforms: Demographics, Lifestyle, and Disease Characteristics
    Emily J. Hadgkiss, George Alexander Jelinek, Tracey Joy Weiland, Naresh G. Pereira, Claudia H. Marck, Dania M. van der Meer · 2013 · Neurology Research International
  44. Effects of immunomodulatory treatment with subcutaneous interferon beta-1a oncognitive decline in mildly disabled patients with relapsing—remitting multiple sclerosis
    Francesco Patti, Maria Pia Amato, Stefano Bastianello, Luisa Maria Caniatti, Elisabetta Di Monte, Patrizia Ferrazza, Benedetta Goretti, Paolo Gallo, Vincenzo Brescia Morra, Salvatore Lo Fermo et al. · 2009 · Multiple Sclerosis Journal
  45. Gender differences in health-related quality of life in multiple sclerosis
    Ilaria Casetta, Trond Riise, Monica Wammen Nortvedt, Nicholas Tiberio Economou, Riccardo De Gennaro, Patrik Fazio, Edward Cesnik, Vittorio Govoni, Enrico Granieri · 2009 · Multiple Sclerosis Journal
  46. Home based management in multiple sclerosis: results of a randomised controlled trial
    Carlo Pozzilli · 2002 · Journal of Neurology Neurosurgery & Psychiatry
  47. The ALS Health Profile Study: quality of life of amyotrophic lateral sclerosis patients and carers in Europe
    Jenkinson, C., Fitzpatrick, R., Swash, M., Peto, V. · 2000 · Journal of Neurology
  48. Treatment for depression and its relationship to improvement in quality of life and psychological well-being in multiple sclerosis patients
    Hart, Stacey, Fonareva, Irina, Merluzzi, Natalia, Mohr, David C. · 2005 · Quality of Life Research
  49. Teriflunomide for multiple sclerosis
    Dian He, Chao Zhang, Xia Zhao, Yifan Zhang, Qingqing Dai, Yuan Li, Lan Chu · 2016 · Cochrane Database of Systematic Reviews
  50. Peer support groups in multiple sclerosis: current effectiveness and future directions
    Michele Messmer Uccelli, L Mancuso Mohr, Mario Alberto Battaglia, P. Zagami, David C. Mohr · 2004 · Multiple Sclerosis Journal
  51. General health status measures for people with cognitive impairment: learning disability and acquired brain injury
    R.P. Riemsma, C. A. Forbes, Julie Glanville, Alison J. Eastwood, Jos Kleijnen · 2001 · Health Technology Assessment
  52. Sensory integration balance training in patients with multiple sclerosis: A randomized, controlled trial
    Marialuisa Gandolfi, Daniele Munari, Christian Geroin, Alberto Gajofatto, Maria Donata Benedetti, Alessandro Midiri, Carla Fontana, Alessandro Picelli, Andreas Waldner, Nicola Smania · 2015 · Multiple Sclerosis Journal
  53. Population based cost utility study of interferon beta-1b in secondary progressive multiple sclerosis
    R. B Forbes, A. Lees, Norman R Waugh, Robert J Swingler · 1999 · BMJ
  54. Cognition, mood and fatigue in patients in the early stage of multiple sclerosis.
    S. Simioni, C. Ruffieux, L. Bruggimann, J. Annoni, M. Schluep · 2007 · Swiss medical weekly
  55. Health status of people with multiple sclerosis: a community mail survey
    Alessandra Solari, Davide Radice · 2001 · Neurological Sciences
  56. A Low-Cost Cognitive Rehabilitation With a Commercial Video Game Improves Sustained Attention and Executive Functions in Multiple Sclerosis
    Laura De Giglio, Francesca De Luca, Luca Prosperini, Giovanna Borriello, Valentina Bianchi, Patrizià Pantano, Carlo Pozzilli · 2014 · Neurorehabilitation and neural repair
  57. Cognitive function and quality of life in multiple sclerosis patients.
    R Cutajar, Elisa Ferriani, Cinzia Scandellari, Loredana Sabattini, Carmela Trocino, Lino P. Marchello, Sergio Stecchi · 2000 · PubMed
  58. Determinants of health-related quality of life in multiple sclerosis: the role of illness intrusiveness
    Marla A. Shawaryn, K. M. Schiaffino, Nicholas G. LaRocca, M V Johnston · 2002 · Multiple Sclerosis Journal
  59. Depression, fatigue and disability are independently associated with quality of life in patients with multiple Sclerosis: Results of a cross-sectional study.
    S. Schmidt, Petra Jöstingmeyer · 2019 · Multiple Sclerosis and Related Disorders
  60. The Hungarian validation of the Brief International Cognitive Assessment for Multiple Sclerosis (BICAMS) battery and the correlation of cognitive impairment with fatigue and quality of life
    Dániel Sandi, Tibor Rudisch, Judit Füvesi, Zsanett Fricska‐Nagy, Hajnalka Huszka, Tamás Biernacki, Dawn Wendy Langdon, Éva Langane, László Vécsei, Krisztina Bencsik · 2015 · Multiple Sclerosis and Related Disorders
  61. Health-Related Quality of Life in Patients with Multiple Sclerosis: Impact of Disease-Modifying Drugs
    Peter Joseph Jongen · 2017 · CNS Drugs
  62. Utilization of unconventional treatments by persons with MS: Is it alternative or complementary?
    Carolyn Emily Schwartz, Elissa Laitin, Sally Brotman, Nicholas G. LaRocca · 1999 · Neurology
  63. A longitudinal study of quality of life and side effects in patients with multiple sclerosis treated with interferon beta-1a
    Zivadinov, Robert, Zorzon, Marino, Tommasi, Maria Antonietta, Nasuelli, Davide, Bernardi, Monica, Monti-Bragadin, Luisa, Cazzato, Giuseppe · 2003 · Journal of the Neurological Sciences
  64. Interferons-beta versus glatiramer acetate for relapsing-remitting multiple sclerosis
    L. La Mantia, Carlo Di Pietrantonj, Marco Rovaris, Giulio Rigon, Serena Frau, Francesco Berardo, Anna Gandini, Anna Longobardi, Bianca Weinstock‐Guttman, Alberto Vaona · 2016 · Cochrane Database of Systematic Reviews
  65. Online meditation training for people with multiple sclerosis: a randomized controlled trial
    Cavalera, Cesare, Rovaris, Marco, Mendozzi, Laura, Pugnetti, Luigi, Garegnani, Massimo, Castelnuovo, Gianluca, Molinari, Enrico, Pagnini, Francesco · 2019 · Multiple Sclerosis Journal
  66. The impact of multiple sclerosis on sexuality and relationships
    Marita P. McCabe, Elizabeth A. McDonald, Amanda A. Deeks, Lindsay Vowels, Marilyn J. Cobain · 1996 · The Journal of Sex Research
  67. The effect of low-dose naltrexone on quality of life of patients with multiple sclerosis: a randomized placebo-controlled trial
    Naser Sharafaddinzadeh, Ali Moghtaderi, Davood Kashipazha, Nastaran Majdinasab, Bita Shalbafan · 2010 · Multiple Sclerosis Journal
  68. Factors influencing healthy aging with multiple sclerosis: a qualitative study
    Michelle Ploughman, Mark W. Austin, Michelle Murdoch, Anne Kearney, John D. Fisk, Marshall S Godwin, Mark Stefanelli · 2011 · Disability and Rehabilitation
  69. Quality of life in patients with multiple sclerosis and its association with depressive symptoms and physical disability
    Adriana Ochoa, Tania Gabriela Hernández Mojica, Francisco Paz-Rodríguez, Aurelio Jara‐Prado, Zoila Trujillo-de los Santos, María Alejandra Sánchez-Guzmán, Jorge Luis Guerrero‐Camacho, Teresa Corona, José Flores, Alejandra Camacho‐Molina et al. · 2019 · Multiple Sclerosis and Related Disorders
  70. Hippotherapy for patients with multiple sclerosis: A multicenter randomized controlled trial (MS-HIPPO)
    Vanessa Vermöhlen, Petra Schiller, Sabine Schickendańtz, Marion Drache, Sabine Hussack, Andreas Gerber‐Grote, Dieter Pöhlau · 2017 · Multiple Sclerosis Journal
  71. A cost-utility analysis of interferon beta for multiple sclerosis.
    Parkin, Paul McNamee, Jacoby, M. A. Miller, Thomas, Bates · 1998 · Health Technology Assessment
  72. Psychological status of patients with relapsing-remitting multiple sclerosis during coronavirus disease-2019 outbreak
    Aleksandar Stojanov, Marina Malobabić, Vuk Milošević, Jelena Stojanov, Slobodan Vojinović, Goran Stanojević, Miloš Stević · 2020 · Multiple Sclerosis and Related Disorders
  73. Sexual problems among women with multiple sclerosis
    Effat Merghati Khoei, Kowsar Qaderi, Leila Amini, Jeffrey E. Korte · 2013 · Journal of the Neurological Sciences
  74. Factors that impact health-related quality of life in neuromyelitis optica spectrum disorder: anxiety, disability, fatigue and depression
    Ziyan Shi, Hongxi Chen, Zhiyun Lian, Ju Liu, Huiru Feng, Hongyu Zhou · 2016 · Journal of Neuroimmunology
  75. Fatigue, Sleep Quality, and Disability in Relation to Quality of Life in Multiple Sclerosis
    Fatemeh Moghaddam Tabrizi, Moloud Radfar · 2015 · International Journal of MS Care
  76. Cannabis and cannabinoids for symptomatic treatment for people with multiple sclerosis
    Filippini, Graziella, Minozzi, Silvia, Borrelli, Francesca, Cinquini, Michela, Dwan, Kerry · 2022 · Cochrane Database Systematic Reviews
  77. Patient‐reported outcomes in multiple sclerosis: a systematic comparison of available measures
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  78. Effects of home-based virtual reality telerehabilitation system in people with multiple sclerosis: A randomized controlled trial
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  80. Depression and Immunity: Inflammation and Depressive Symptoms in Multiple Sclerosis
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  81. Treatment with Interferon Beta-1b Improves Quality of Life in Multiple Sclerosis
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  82. Outcome measures for multiple sclerosis clinical trials: relative measurement precision of the Expanded Disability Status Scale and Multiple Sclerosis Functional C omposite
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  83. Contributing factors to depressed mood in multiple sclerosis
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  85. Chronic Pain in Persons with Multiple Sclerosis
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  86. Measuring quality of life in multiple sclerosis patients with urinary disorders using the qualiveen questionnaire11No commercial party having a direct financial interest in the results of the research supporting this article has or will confer a benefit on the author(s) or on any organization with which the author(s) is/are associated.
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  87. Pilot evaluation of a resilience training program for people with multiple sclerosis
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  88. Evaluation of health-related quality of life, fatigue and depression in neuromyelitis optica
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  89. Interferon-β1b in the treatment of secondary progressive MS
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  90. Sexual disorders in women with MS: Assessment and management
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  91. Evaluating Sativex® in Neuropathic Pain Management: A Clinical and Neurophysiological Assessment in Multiple Sclerosis
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  92. Evolution of Patient-Reported Outcomes and Their Role in Multiple Sclerosis Clinical Trials
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  93. Pain and Quality of Life in the Early Stages After Multiple Sclerosis Diagnosis: A 2-year Longitudinal Study
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  94. Depressive symptoms in a treated multiple sclerosis cohort
    Scott Burton Patten, Shanika Fridhandler, Cynthia A Beck, Luanne M. Metz · 2003 · Multiple Sclerosis Journal
  95. A randomized, double-blind, placebo-controlled, two-period, crossover, pilot trial of lamotrigine in patients with central pain due to multiple sclerosis
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  96. Can Aerobic Exercise Training Affect Health-Related Quality of Life for People with Multiple Sclerosis?
    Georgina Ann Sutherland, Mark B. Andersen, Mark A Stoove · 2001 · Journal of Sport and Exercise Psychology
  97. Neuro-ophthalmologic evaluation, quality of life, and functional disability in patients with MS
    Elena García‐Martín, Diego Rodríguez Mena, Raquel Herrero, Carmen Almárcegui, Isabel Dolz, Jesús Martín, J.R. Ara, José Manuel Larrosa, Vicente Polo, Javier Fernández et al. · 2013 · Neurology
  98. Visuo-proprioceptive training reduces risk of falls in patients with multiple sclerosis
    Luca Prosperini, Laura Leonardi, Paolo De Carli, Maria Letizia Mannocchi, Carlo Pozzilli · 2010 · Multiple Sclerosis Journal
  99. Qualiveen: A Urinary Disorder−Specific Instrument for Use in Clinical Trials in Multiple Sclerosis
    V. Bonniaud, Dianne Bryant, B. Parratte, P. Gallien, Gordon Henry Guyatt · 2006 · Archives of Physical Medicine and Rehabilitation
  100. Does adding MS-specific items to a generic measure (the SF-36) improve measurement?
    Jennifer A. Freeman, Jeremy Charles Hobart, Alan J. Thompson · 2001 · Neurology