Seizures following the withdrawal of long-term treatment with mianserin
Abstract
Seizures were observed following the withdrawal of mianserin 60 mg/day for 2 years. To our knowledge, this is the first report of convulsions after suspension of an antidepressant. This phenomenon was observed in a young woman (with no history of epilepsy or other organic diseases that may induce seizures) 10 days after abrupt discontinuation of long-term treatment with mianserin.
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Discontinuation symptoms differ in prevalence according to the pharmacological profile of the antidepressant.
“and differ in prevalence according to the pharmacological profile of the antidepressant [89].”
From Acute and Persistent Withdrawal Syndromes Following Discontinuation of Psychotropic Medications (2020) · cites this paper as [89]
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Acute and Persistent Withdrawal Syndromes Following Discontinuation of Psychotropic Medications
Cosci, F., & Chouinard, G. (2020) · Psychotherapy and Psychosomatics · doi:10.1159/000506868 · Cited by 265 · see citing works
- Authors
- De Leo, D., Dalla Barba, G., & Zanchin, G.
- Affiliations
- University of Padua (IT)
- Venue
- The Italian Journal of Neurological Sciences
- Published
- 1988-04
- Volume
- 9
- Issue
- 2
- Pages
- 167-169
- ISSN
- 0392-0461 (ISSN-L)
- 1126-5442
- OpenAlex
- W1974086564
- Cited by
- 1
- References
- 18
- Citations by year
- 2020: 1
- FWCI
- 0.00
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- The Italian Journal of Neurological Sciences (publishedVersion)
- PubMed (publishedVersion)
- Padua Research Archive (University of Padova) (submittedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Epilepsy research and treatment
- Health Sciences › Medicine › Psychiatry and Mental health › Electroconvulsive Therapy Studies
- Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
- Keywords
- mianserin, seizures, drug withdrawal, antidepressant discontinuation, adverse drug reactions, serotonin reuptake inhibitors, convulsions
- MeSH terms
- Adult, Depressive Disorder, Female, Humans, Mianserin, Seizures, Substance Withdrawal Syndrome
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