Serum proinsulin levels at fasting and after oral glucose load in patients with Type 2 (non-insulin-dependent) diabetes mellitus

Yoshioka, N., Kuzuya, T., Matsuda, A., Taniguchi, M., Iwamoto, Y.·1988·Diabetologia

Cited by (175)

Items 101–175 of 175

  1. Improved Beta Cell Function, with Reduction in Secretion of Intact and 32/33 Split Proinsulin, after Dietary Intervention in Subjects with Type 2 Diabetes Mellitus
    Melanie Jane Davies, J. Metcalfe, J. L. Day, Ana Grenfell, C. Nicholas Hales, I. Peter Gray · 1994 · Diabetic Medicine
  2. Chronic Sulfonylurea Treatment and Hyperglycemia Aggravate Disproportionately Elevated Plasma Proinsulin Levels in Patients with Type 2 Diabetes.
    Toyoshi Inoguchi, Fumio Umeda, MAIKO KAKIMOTO, Yasuhiro Sako, Hidehiro Ishii, KATSUMI NODA, Makoto Kunisaki, Minako Imamura, HM-YAN YU, Takashi Etoh et al. · 2000 · Endocrine Journal
  3. The serum levels of proinsulin and their relationship with IGFBP‐1 in obese children
    Tomohiro Kamoda, H. Saitoh, Michiharu Inudoh, Kunihiko Miyazaki, Akira Matsui · 2005 · Diabetes Obesity and Metabolism
  4. Evidence for Impaired Pancreatic Beta Cell Function in South African Indians with Impaired Glucose Tolerance
    Ayesha Ahmed Motala, M. A. K. Omar · 1994 · Diabetic Medicine
  5. Are specific serum insulin levels low in impaired glucose tolerance and type II diabetes?: Measurement with a radioimmunoassay blind to proinsulin, in the population of Wadena, Minnesota
    F. C. Goetz, Lindsey French, William T. B. Thomas, Ronald L. Gingerich, J.P. Clements · 1995 · Metabolism
  6. Relationship between proinsulin-to-insulin ratio and advanced glycation endproducts in Japanese type 2 diabetic subjects
    Yoshifumi Saisho, Taro Maruyama, Hiroshi Hirose, Takao Saruta · 2007 · Diabetes Research and Clinical Practice
  7. Specific insulin and proinsulin concentrations in nondiabetic South Indians
    Chamukuttan Snehalatha, Ambady Ramachandran, K. Satyavani, Vijay Viswanathan, Steven M. Haffner · 1998 · Metabolism
  8. Subtotal pancreatectomy for hypoglycemia due to congenital hyperinsulinism: long-term follow-up of neurodevelopmental and pancreatic function
    Kristina I. Rother, Jane M. S. Matsumoto, Norman H. Rasmussen, W Frederick Schwenk · 2001 · Pediatric Diabetes
  9. Association of proinsulin and insulin resistance with coronary artery disease in non‐diabetic south Indian men
    Chamukuttan Snehalatha, Ambady Ramachandran, I. Saltyamurthy, K. Satyavani, Selvaraj Sivasankari, Jaya Misra, Vijay Viswanathan · 2001 · Diabetic Medicine
  10. PROINSULIN, PROAMYLIN AND THE BETA CELL ENDOPLASMIC RETICULUM: THE KEY FOR THE PATHOGENESIS OF DIFFERENT DIABETES PHENOTYPES
    Constantin Ionescu-Tirgoviste, Cristian Guja · 2007
  11. Hyperproinsulinemia is not a characteristic feature in the offspring of patients with different phenotypes of type II diabetes
    IK Vauhkonen, L Niskanen, Leena Moilanen Mykkänen, SM Haffner, MI Uusitupa, Markku Laakso · 2000 · European Journal of Endocrinology
  12. Proinsulin: Biosynthesis, conversion, assay methods and clinical studies
    Thomas R. Csorba · 1991 · Clinical Biochemistry
  13. A sensitive and reliable method for assaying true human insulin without interaction with human proinsulin-like molecules
    Lucilla Domenica Monti, Emilia P. Sandoli, V. C. Phan, PierMarco Piatti, Sabrina Costa, Antonio Secchi, Guido Pozza · 1995 · Acta Diabetologica
  14. Proinsulin immunoreactivity in identical twins discordant for noninsulin-dependent diabetes mellitus.
    Michael Einar Røder, Allan Arthur Vaag, SVEND G. HARTLING, Bo Dinesen, Susanne Lanng, Henning Beck‐Nielsen, Christian Binder · 1995 · The Journal of Clinical Endocrinology & Metabolism
  15. Immunoradiometric assay of human intact proinsulin applied to patients with type 2 diabetes, impaired glucose tolerance, and hyperandrogenism
    Didier Chevenne, J Ruiz, L Lohmann, Antoine Laudat, Hélène Leblanc, I. Peter Gray, Philippe Passa, Dominique Porquet · 1994 · Clinical Chemistry
  16. Proinsulin maturation disorder is a contributor to the defect of subsequent conversion to insulin in β-cells
    Jie Wang, Kwame Osei · 2011 · Biochemical and Biophysical Research Communications
  17. Non‐insulin dependent diabetes mellitus: defects in insulin secretion
    Bruce H. R. Wolffenbuttel, Timon W. van Haeften · 1993 · European Journal of Clinical Investigation
  18. Evaluation of two insulin assays in insulin resistance syndrome (syndrome X).
    Steven M. Haffner, Leena Mykkänen, Rodolfo A. Valdez, Michael P. Stern · 1994 · Arteriosclerosis and Thrombosis A Journal of Vascular Biology
  19. Cross-Sectional and Prospective Associations Between Proinsulin and Cardiovascular Disease Risk Factors in a Population Experiencing Rapid Cultural Transition
    Anthony J. Hanley, Gail McKeown‐Eyssen, Stewart B. Harris, Robert Alexander Hegele, Thomas M. S. Wolever, Jeremy Kwan, Philip W. Connelly, Bernard Zinman · 2001 · Diabetes Care
  20. Biophysical alteration of the secretory track in β-cells due to molecular overcrowding: the relevance for diabetes
    Constantin Ionescu-Tirgoviste, Florin Despa · 2010 · Integrative Biology
  21. Insulin resistance and impaired insulin secretion due to phosphofructo-1-kinase-deficiency in humans
    Michael Ristow, Matthias Vorgerd, Matthias Möhlig, Helmut Schatz, Andreas F. H. Pfeiffer · 1999 · Journal of Molecular Medicine
  22. Proinsulin: recent observations and controversies
    Robert Brian Mackin · 1998 · Cellular and Molecular Life Sciences
  23. Processing and release of human proinsulin-cleavage products into culture media by different engineered non-endocrine cells: a specific assessment by capillary electrophoresis
    Cinzia Arcelloni, Luca Falqui, Sabina Martinenghi, Angela Stabilini, A. E. Pontiroli, Rita Clara Paroni · 2000 · Journal of Endocrinology
  24. Estimated proinsulin processing activity of prohormone convertase (PC) 1/3 rather than PC2 is decreased in pancreatic β-cells of type 2 diabetic patients
    Sachihiko Ozawa, Hidenori Katsuta, Kiyoshi Suzuki, Kazuto Takahashi, Toshiaki Tanaka, Yoshikazu Sumitani, Susumu Nishida, Katsuhiko Yoshimoto, Hitoshi Ishida · 2014 · Endocrine Journal
  25. Effect of acarbose on glycemic control and lipid metabolism in patients with non—insulin-dependent diabetes mellitus
    Tomokazu Kawamura, Genshi Egusa, Rumi Fujikawa, Takehiko Watanabe, Kiyoshi Oda, Shinkuro Kataoka, Sadamatsu Takayama, Keiji Kubo, Shinichi Yamamoto, Koji Noma et al. · 1998 · Current Therapeutic Research
  26. Proinsulin is sensitive to reflect glucose intolerance
    Akinobu Nakamura, Hideaki Miyoshi, Shigekazu Ukawa, Koshi Nakamura, Takafumi Nakagawa, Yasuo Terauchi, Akiko Tamakoshi, Tatsuya Atsumi · 2019 · Journal of Diabetes Investigation
  27. Association of Serum Proinsulin With Hormone Replacement Therapy in Nondiabetic Older Women
    Dong‐Jun Kim, Elizabeth L. Barrett-Connor · 2006 · Diabetes Care
  28. Insulin and Proinsulin Dynamics Progressively Deteriorate From Within the Normal Range Toward Impaired Glucose Tolerance
    Norimitsu Murai, Naoko Saito, Eriko Kodama, Tatsuya Iida, Kentaro Mikura, Hideyuki Imai, Mariko Kaji, Mai Hashizume, Yasuyoshi Kigawa, Go Koizumi et al. · 2020 · Journal of the Endocrine Society
  29. Parallel changes of proinsulin and islet amyloid polypeptide in glucose intolerance
    C.M MacNamara, Beryl A. Barrow, Susan E. Manley, J Lévy, Anne Clark, R. C. Turner · 2000 · Diabetes Research and Clinical Practice
  30. Normal proinsulin processing despite beta-cell dysfunction in persistent hyperinsulinaemic hypoglycaemia of infancy (nesidioblastosis)
    Gil Leibowitz, N. Weintrob, Alon J. Pikarsky, ZEEV JOSEFSBERG, Heddy Landau, Benjamin Gläser, Charles Nicholas Hales, Erol Cerasi · 1996 · Diabetologia
  31. Effects of genetic predisposition on proinsulin responses in Asian Indians
    Ambady Ramachandran, Chamukuttan Snehalatha, K. Satyavani, Vijay Viswanathan · 1998 · Diabetes Research and Clinical Practice
  32. Effects of Glimepiride vs Glibenclamide on Ischaemic Heart Disease Risk Factors and Glycaemic Control in Patients with Type 2 Diabetes Mellitus
    Mary E Britton, A. E. Denver, Vidya Mohamed‐Ali, John S Yudkin · 1998 · Clinical Drug Investigation
  33. Abnormalities of Insulin Secretion and β‐Cell Defects in Type 2 Diabetes
    Mazen Alsahli, John E. Gerich · 2010 · Wiley eBooks
  34. Hyperproinsulinemia in obesity and in type 2 diabetes and its relation to cardiovascular disease
    Michael Einar Røder · 2017 · Expert Review of Endocrinology & Metabolism
  35. Comparisons between dipeptidyl peptidase-4 inhibitors and other classes of hypoglycemic drugs using two distinct biomarkers of pancreatic beta-cell function: A meta-analysis
    Masahiro Takahashi, 柴崎美紗, Hirotoshi Echizen, Akifumi Kushiyama · 2020 · PLoS ONE
  36. Insulin secretion and insulin sensitivity are normal in non‐diabetic subjects from maternal inheritance diabetes and deafness families
    Dianne Jane Holmes‐Walker, Glenn M. Ward, STEVEN C. BOYAGES · 2001 · Diabetic Medicine
  37. Proportional proinsulin responses in first-degree relatives of patients with type 2 diabetes mellitus
    M. E. R�der, Johan Gunnar Eriksson, SVEND G. HARTLING, Per‐Henrik Groop, Christian Binder · 1993 · Acta Diabetologica
  38. β‐Cell Dysfunction in Type 2 Diabetes
    Kristina M. Utzschneider, Steven E. Kahn · 2003 · Wiley eBooks
  39. Insulin, proinsulin and insulin resistance status in relation to lipid profiles among school children in Taiwan—The Taipei Children Heart Study
    An‐Tsz Hsieh, Nain‐Feng Chu, Muh‐Han Shen, Der‐Min Wu, Dan-Jiang Wang, Shih-Ming Hsieh · 2003 · Clinical Biochemistry
  40. The association between impaired proinsulin processing and type 2 diabetes mellitus in non-obese Japanese individuals
    Hidenori Katsuta, Sachihiko Ozawa, Kiyoshi Suzuki, Kazuto Takahashi, Toshiaki Tanaka, Yoshikazu Sumitani, Susumu Nishida, Takuma Kondo, Toshio Hosaka, Kouichi Inukai et al. · 2015 · Endocrine Journal
  41. Desenvolvimento de um radioimunoensaio de dexametasona no soro como subsídio para o diagnóstico da síndrome de Cushing
    Lilian Fukusima Hayashi, Keiko O Noguti, Odete Hirata Nakamura, Claudio Elias Kater, José Gilberto Henrique Vieira · 2011 · Jornal Brasileiro de Patologia e Medicina Laboratorial
  42. Plasma proinsulin in recently diagnosed type 2 diabetes mellitus
    Robert S. Schmidli, Cassandra Hagan, Russell S. Scott, James Livesey, Louisa V. Forbes · 1993 · Diabetes Research and Clinical Practice
  43. Subgroup analysis of proinsulin and insulin levels reveals novel correlations to metabolic indicators of type 2 diabetes
    Tangying Li, Huibiao Quan, Huachuan Zhang, Leweihua Lin, Lin Lü, Qianying Ou, Kaining Chen · 2020 · Aging
  44. Diabetes mellitus tipo 2: fatores preditivos na população nipo-brasileira
    Rogéria do Nascimento, Laércio Joel Franco, Suely Godoy Agostinho Gimeno, Amélia T Hirai, Sandra Roberta G. Ferreira · 2003 · Arquivos Brasileiros de Endocrinologia & Metabologia
  45. Proinsulin conversion intermediates: a possible source of confusion
    P. A. Halban · 1991 · Diabetologia
  46. Tumor and Serum Levels of Proinsulin and Insulin in Insulinoma Patients.
    YOSHIMASA TASAKA, Fumio Nakaya, Hiroshi Matsumoto, REIKO ODAGIRI, Hisako Ohgawara, Yasue Omori · 1993 · Endocrine Journal
  47. Pathogenesis of Type 2 Diabetes
    Kenneth J. Cusi, Ralph A. DeFronzo · 2001 · Comprehensive physiology
  48. β-Cell Dysfunction under Hyperglycemic Stress: A Molecular Model
    Florin Despa, R. Stephen Berry · 2010 · Journal of Diabetes Science and Technology
  49. Congenital factor VII deficiency: a case report.
    Latiff A. Zarina, A Hamidah, J Rohana, A.K. Faraizah, A A Noryati, R Jamal, NY Boo · 2004 · PubMed
  50. Elevated ratio of summed serum proinsulin to insulin response after oral glucose load in Type 2 diabetes decreases following sulfonylurea treatment
    Shinobu Kumakura, Yasuhiko Iwamoto, Takeshi Kuzuya, Ikuo Shiraishi, Ayako Matsuda, Toshikazu Saito · 1995 · Diabetes Research and Clinical Practice
  51. Physiological Increase in Plasma Insulin Concentration Suppresses Proinsulin Secretion in Normal Controls but not in Subjects with Glucose Intolerance.
    Taro Wasada, Hiroyuki Kuroki, HIROKO ARII, Akiko Maruyama, S Saito, Yasuko Watanabe, Yasue Omori · 1994 · Endocrine Journal
  52. Hyperproinsulinaemia in Acromegaly: Evidence for Abnormal Pancreatic β-Cell Function?
    Rousseau Mariano Gama, J. Derrick Teale, J Wright, Gordon A. Ferns, Vincent Marks · 1997 · Annals of Clinical Biochemistry International Journal of Laboratory Medicine
  53. Application of size-exclusion chromatography in the investigation of the in vitro stability of proinsulin and its cleaved metabolites in human serum and plasma
    Ronald R. Bowsher, Paula F. Santa · 2009 · Journal of Chromatography B
  54. The effects of subcutaneous human proinsulin on the production of split proinsulin, glucose turnover and intermediary metabolism in non-insulin-dependent diabetic man
    Stephen N. Davis, PierMarco Piatti, L. Monti, M. Brown, C. Hetherington, M. Antsiferov, W. Sobey, C. N. Hales, Hans Ørskov, K. G. M. M. Alberti · 1993 · Diabetes Research and Clinical Practice
  55. Inhibitory Action of Oral Thyrotropin-Releasing Hormone on the Glucoregulatory Response of the Oral Glucose Tolerance Test
    Leonidas H. Duntas, Lina Papanastasiou, Aimilia Mantzou, Peter Michael Jehle, IOANNIS MANTZOS, Demetrios A. Koutras · 1998 · Thyroid
  56. Chemical characterization of diabetic herbal tea and in vitro evaluation of glucose transport and metabolism gene expression profile
    Etetor Roland Eshiet · 2010 · ThinkTech (Texas Tech University)
  57. Proinsulin and insulin levels according to glucose tolerance among Japanese-Brazilians, aged 40?79 years
    Lúcia Christina Iochida, Luiz Francisco Marcopito, L J Franco, Sandra Roberta G. Ferreira, Magid Iunes, Ivaldir S Dalbosco, Ewaldo Mario Russo · 1996 · Diabetes Research and Clinical Practice
  58. Specific insulin and proinsulin secretion in glucokinase-deficient individuals
    Victor Cavalcanti Pardini, Gilberto Velho, R. Reis, Saulo Purisch, Hélène Blanché, José Gilberto H. Vieira, Regina S. Moisés · 1999 · Brazilian Journal of Medical and Biological Research
  59. A New Case of Familial Hyperproinsulinemia.
    Toshihiko Hashimoto, Nobunori Aso, Fumio Umeda, TSUKASA YAMASHITA, Hidehiro Ishii, KATSUMI NODA, Toshiharu MOTOMATSU, Hajime Nawata · 1989 · Endocrinologia Japonica
  60. Exenatide substantially improves proinsulin conversion and cell survival that augment Ins2 +/Akita beta cell function
    Wei Tang, Qingxin Yuan, Bo Xu, Kwame Osei, Jie Wang · 2016 · Molecular and Cellular Endocrinology
  61. Pathophysiologie des Diabetes mellitus Typ2
    Klaus Dieter Palitzsch, Cornelius Bollheimer · 2001 · Springer eBooks
  62. Dissimilar association of conventional immuno-reactive versus specific insulin with cardiovascular risk factors: a consequence of proinsulinaemia?
    P.A. Grootenhuis, J.M. Mooy, P.J. Kostense, C. Popp‐Snijders, L.M. Bouter, Robert J. Heine · 1998 · Diabetes Research and Clinical Practice
  63. Evaluation of specific genotypes in the context of the type 2 diabetes risk phenotype in the black South African population
    Hester Johanna Kotzé · 2010 · Boloka Institutional Repository (North-west University)
  64. Alterações lipídicas na população nipo-brasileira de Mombuca - Guatapará-SP
    Roberta Carvalho de Figueiredo · 2007
  65. Proinsulin level as a predictor of metabolic syndrome in the romanian population
    Simona Ateia, Emilia Rusu, S. Ateia, Cristescu Vasilica, Georgiana Enache, Adrian Costache, Gabriela Radulian, D Cheţa · 2013 · Romanian Journal of Diabetes Nutrition and Metabolic Diseases
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  67. Hyperproinsulinaemia and Islet Dysfuction in the NIDDM-Like Syndrome of Psammomys obesus
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  68. Assessment and Treatment of Impaired Insulin- Secretion and Action in Type 2 Diabetes
    Mozhgan Dorkhan · 2008 · Lund University Publications (Lund University)
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  74. Pathogenesis of Type 2 Diabetes
    Kenneth J. Cusi, Ralph Anthony DeFronzo · 2001 · Comprehensive physiology
  75. In Silico Hypothesis Testing in Drug Discovery: Using Quantitative Systems Pharmacology Modeling to Evaluate the Therapeutic Value of Proinsulin Conversion to Insulin Therapy for Type 2 Diabetes Mellitus
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