Mathematical model of the human renal system.
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The rate of fluid reabsorption from the distal tubules and collecting ducts depends on the influence of plasma vasopressin concentration.
“The rate of fluid reabsorption from the distal tubules and collecting ducts depends on the influence of plasma vasopressin concentration, which was determined in the Uttamsingh model (Uttamsingh et al., 1985) on the basis of experimental measurements (Dehaven and Shapiro, 1970).”
From Thoroughly Calibrated Modular Agent-Based Model of the Human Cardiovascular and Renal Systems for Blood Pressure Regulation in Health and Disease (2021) · cites this paper as Uttamsingh et al., 1985
In the absence of significant amounts of poorly reabsorbable solutes, the fraction of the water load passively reabsorbed in the proximal tubule is equal to the fraction of the sodium load reabsorbed.
“In the absence of significant amounts of poorly reabsorbable solutes, the fraction of the water load passively reabsorbed in the proximal tubule is equal to the fraction of the sodium load reabsorbed (Uttamsingh et al., 1985).”
From Thoroughly Calibrated Modular Agent-Based Model of the Human Cardiovascular and Renal Systems for Blood Pressure Regulation in Health and Disease (2021) · cites this paper as Uttamsingh et al., 1985
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“A number of such models have already been used to investigate different aspects of individual systems and processes of the human body (Guyton et al., 1972; Ikeda et al., 1979; Uttamsingh et al., 1985; Ottesen et al., 2004; Karaaslan et al., 2005, 2014; Proshin and Solodyannikov, 2006; Abram et al., 2007; Thomas et al.…”
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- Authors
- Uttamsingh, R. J., Leaning, M. S., Bushman, J. A., Carson, E. R., & Finkelstein, L.
- Affiliations
- City, University of London (GB)
- Royal College of Surgeons of England (GB)
- Venue
- Medical & Biological Engineering & Computing
- Published
- 1985-11
- Volume
- 23
- Issue
- 6
- Pages
- 525-535
- ISSN
- 0140-0118 (ISSN-L)
- 1741-0444
- OpenAlex
- W1979341804
- Cited by
- 59
- References
- 45
- Citations by year
- 2026: 1 · 2024: 3 · 2023: 2 · 2022: 2 · 2021: 2 · 2020: 3 · 2019: 2 · 2017: 1 · 2016: 2 · 2015: 4 · 2014: 2 · 2013: 3 · 2012: 3
- FWCI
- 1.78
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Medical & Biological Engineering & Computing (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Electrolyte and hormonal disorders
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Ion Transport and Channel Regulation
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
- Keywords
- renal system, mathematical model, fluid balance, vasopressin, renal physiology
- MeSH terms
- Homeostasis, Humans, Kidney, Mathematics, Models, Biological, Water-Electrolyte Balance
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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