Tyrosine Hydroxylase and Parkinson’s Disease

Haavik, Jan, Toska, Karen·1998·Molecular Neurobiology

Cited by (264)

Items 101–200 of 264

  1. Investigations into Potential Extrasynaptic Communication between the Dopaminergic and Nitrergic Systems
    Mišo Mitkovski, Fernando E. Padovan‐Neto, Rita Raisman‐Vozari, Laure Ginestet, Célia Aparecida da-Silva, E. A. Del-Bel · 2012 · Frontiers in Physiology
  2. Melatonin-Loaded Nanoparticles Augment Mitophagy to Retard Parkinson’s Disease
    Liku Biswal, Mohammed Nadim Sardoiwala, Avinash Chandra Kushwaha, Syamantak Mukherjee, Surajit Karmakar · 2024 · ACS Applied Materials & Interfaces
  3. In silicothermodynamics stability change analysis involved in BH4responsive mutations in phenylalanine hydroxylase: QM/MM and MD simulations analysis
    Nidhi Chadha, Anjani K. Tiwari, Vikas Kumar, Marilyn Daisy Milton, Anil Kumar Mishra · 2014 · Journal of Biomolecular Structure and Dynamics
  4. Neurorestorative effects of sub-chronic administration of ambroxol in rodent model of Parkinson’s disease
    Akanksha Mishra, Sairam Krishnamurthy · 2019 · Naunyn-Schmiedeberg s Archives of Pharmacology
  5. A Knockin Reporter Allows Purification and Characterization of mDA Neurons from Heterogeneous Populations
    Ninuo Xia, Fang Fang, Pengbo Zhang, Jun Cui, Chhavy Tep-Cullison, Tim Hamerley, Hyun Joo Lee, Theo D. Palmer, Brian B. Bothner, Jin Hyung Lee et al. · 2017 · Cell Reports
  6. Dexmedetomidine Ameliorates Sleep Deprivation-Induced Depressive Behaviors in Mice
    Eun-Jin Moon, Il‐Gyu Ko, Sung‐Eun Kim, Jun‐Jang Jin, Lakkyong Hwang, Chang‐Ju Kim, Hyeonjun An, Bong-Jae Lee, Jae-Woo Yi · 2018 · International Neurourology Journal
  7. Effect of treadmill exercise on social interaction and tyrosine hydroxylase expression in the attention-deficit/ hyperactivity disorder rats
    Dae-Jung Baek, Chae-Bin Lee, Seung‐Soo Baek · 2014 · Journal of Exercise Rehabilitation
  8. Personalized Medicine to Improve Treatment of Dopa-Responsive Dystonia—A Focus on Tyrosine Hydroxylase Deficiency
    Gyrid Nygaard, Peter D. Szigetvari, Ann Kari Grindheim, Peter Ruoff, Aurora Martı́nez, Jan Haavik, Rune Kleppe, Marte I. Flydal · 2021 · Journal of Personalized Medicine
  9. Hordenine inhibits neuroinflammation and exerts neuroprotective effects via inhibiting NF-κB and MAPK signaling pathways in vivo and in vitro
    Su, Yingchun, Liu, Yanting, He, Dewei, Hu, Guiqiu, Wang, Hefei, Ye, Bojian, He, Yuan, Gao, Xiyu, Liu, Dianfeng · 2022 · International Immunopharmacology
  10. Agathobaculum butyriciproducens Shows Neuroprotective Effects in a 6-OHDA-Induced Mouse Model of Parkinson’s Disease
    Da Woon Lee, Young‐Kyoung Ryu, Dong‐Ho Chang, Hye‐Yeon Park, Jun Go, So-Young Maeng, Dae Youn Hwang, Byoung‐Chan Kim, Chul‐Ho Lee, Kyoung‐Shim Kim · 2022 · Journal of Microbiology and Biotechnology
  11. Effects of Treadmill Exercise on the Recovery of Dopaminergic Neuron Loss and Muscle Atrophy in the 6-OHDA Lesioned Parkinson's Disease Rat Model
    Myoung‐Ae Choe, Byung‐Soo Koo, Gyeong Ju An, Songhee Jeon · 2012 · Korean Journal of Physiology and Pharmacology
  12. The quaternary structure of human tyrosine hydroxylase: effects of dystonia‐associated missense variants on oligomeric state and enzyme activity
    Peter D. Szigetvari, Gopinath Muruganandam, Juha Pekka Kallio, Erik Ingmar Hallin, Agnete Fossbakk, Remy Loris, Inari Kursula, Lisbeth Birk Møller, Per Morten Knappskog, Petri Kursula et al. · 2018 · Journal of Neurochemistry
  13. Pharmacological Chaperone Design for Reducing Risk Factor of Parkinson’s Disease from Traditional Chinese Medicine
    Hung-Jin Huang, Cheng-Chun Lee, Calvin Yu‐Chian Chen · 2014 · Evidence-based Complementary and Alternative Medicine
  14. Discovery of compounds that protect tyrosine hydroxylase activity through different mechanisms
    Magnus Hole, Jarl Underhaug, Héctor Díez, Ming Ying, Åsmund K. Røhr, Ana Jorge‐Finnigan, Noèlia Fernàndez-castillo A, Àngels García‐Cazorla, K. Kristoffer Andersson, Knut Teigen et al. · 2015 · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
  15. Decreased dopamine in striatum and difficult locomotor recovery from MPTP insult after exposure to radiofrequency electromagnetic fields
    Ju Hwan Kim, Choong Hyun Lee, Hyunggun Kim, Hak Rim Kim · 2019 · Scientific Reports
  16. Modulation of dopamine metabolizing enzymes and antioxidant status by Capsicum annuum Lin in rotenone-intoxicated rat brain
    Omodesola Oluwafisayo Ogunruku, Bolanle Olanrewaju Ogunyemi, Ganiyu Oboh, Oluwaseun Oyeniyi Babatunde, Aline Augusti Boligon · 2019 · Toxicology Reports
  17. Differential expression of synaptic proteins in unilateral 6‐OHDA lesioned rat model—A comparative proteomics approach
    Yan Xiong, Yongqian Zhang, Javed Iqbal, Ke Ming, Yun Wang, Yujuan Li, Hong Qing, Yulin Deng · 2014 · PROTEOMICS
  18. Noggin Along with a Self-Assembling Peptide Nanofiber Containing Long Motif of Laminin Induces Tyrosine Hydroxylase Gene Expression
    Shima Tavakol, Sayed Mostafa Modaress Musavi, Behnaz Tavakol, Elham Hoveizi, Jafar Ai, Seyed Mahdi Rezayat · 2016 · Molecular Neurobiology
  19. Testosterone enhances mitochondrial complex V function in the substantia nigra of aged male rats
    Tianyun Zhang, Yu Wang, Yunxiao Kang, Li Wang, Hui Zhao, Xiaoming Ji, Yuanxiang Huang, Wensheng Yan, Rui Cui, Guoliang Zhang et al. · 2020 · Aging
  20. Toxic Metabolites and Inborn Errors of Amino Acid Metabolism: What One Informs about the Other
    Namgyu Lee, Dohoon Kim · 2022 · Metabolites
  21. Neurotensin Induces Tyrosine Hydroxylase Gene Activation through Nitric Oxide and Protein Kinase C Signaling Pathways
    Mustapha Najimi, Jean-Jacques Robert, Jacques J. Mallet, William H. Rostène, Patricia Forgez · 2002 · Molecular Pharmacology
  22. Methyl jasmonate ameliorates rotenone-induced motor deficits in rats through its neuroprotective activity and increased expression of tyrosine hydroxylase immunopositive cells
    Akinyinka Alabi, Abayomi Mayowa Ajayi, Benneth Ben‐Azu, Osarume Omorobge, Solomon Umukoro · 2019 · Metabolic Brain Disease
  23. Rapidly and simultaneously quantifying multiple biomarkers of L-tyrosine hydroxylase deficiency by using paper microfluidic devices and smartphone-based analysis system
    Pin-Chuan Chen, Kuan-Han Chen, Chun‐Yi Lin, Yi-Chun Yeh · 2021 · Sensors and Actuators B Chemical
  24. Vitamin D (VD3) Intensifies the Effects of Exercise and Prevents Alterations of Behavior, Brain Oxidative Stress, and Neuroinflammation, in Hemiparkinsonian Rats
    Roberta Oliveira da Costa, Carlos Vinicius Jataí Gadelha-Filho, Pedro Éverson Alexandre de Aquino, Ludmila Araújo Rodrigues Lima, Jalles Dantas de Lucena, Wesley Lyeverton Correia Ribeiro, Francisco Arnaldo Viana Lima, Kelly Rose Tavares Neves, Glauce Socorro de Barros Viana · 2022 · Neurochemical Research
  25. Acylated Ghrelin is Protective Against 6-OHDA-induced Neurotoxicity by Regulating Autophagic Flux
    He, Xin, Yuan, Wei, Liu, Fei, Feng, Juan, Guo, Yanxia · 2021 · Frontiers in Pharmacology
  26. A Comparative Analysis of the Anatomy, Phenolic Profile, and Antioxidant Capacity of Tussilago farfara L. Vegetative Organs
    Viviane Beatrice Bota, Andreea-Adriana Neamțu, Neli-Kinga Oláh, Elisabeta Chișe, Ramona Flavia BURTESCU, Flavia Roxana Pripon Furtuna, Alexandru‐Sabin Nicula, Carmen Neamţu, Adrian Marius Maghiar, Lăcrămioara-Carmen Ivănescu et al. · 2022 · Plants
  27. Neuronal-type-specific epigenome editing to decrease SNCA expression: Implications for precision medicine in synucleinopathies
    Zhiguo Sun, Boris Kantor, Ornit Chiba‐Falek · 2023 · Molecular Therapy — Nucleic Acids
  28. Trabecular meshwork mesenchymal stem cell transplantation improve motor symptoms of parkinsonian rat model
    Hossein Mostafavi, Leila Ghassemifard, Ali Rostami, Mohsen Alipour, Samad Nadri · 2019 · Biologicals
  29. Copper sulfate prevents tyrosine hydroxylase reduced activity and motor deficits in a Parkinson's disease model in mice.
    Mireya Alcaraz-Zubeldia, Marie‐Catherine Boll, Sergio Montes-López, Francisca Pérez‐Severiano, Juan Carlos Martínez‐Lazcano, Araceli Dı́az-Ruiz, Camilo Rı́os · 2009 · PubMed
  30. Identification of molecular network of gut‐brain axis associated with neuroprotective effects of PPARδ‐ligand erucic acid in rotenone‐induced Parkinson's disease model in zebrafish
    İsmail Ünal, Derya Cansız, Mustafa Gani Sürmen, Saime Sürmen, Zehra Sezer, Merih Beler, Ünsal Veli Üstündağ, Elif Güzel, A. Ata Alturfan, Ebru Emekli‐Alturfan · 2022 · European Journal of Neuroscience
  31. Co-Expression Network Analysis Identifies Molecular Determinants of Loneliness Associated with Neuropsychiatric and Neurodegenerative Diseases
    Judith Potashkin, Jose Santiago, James P. Quinn · 2023 · International Journal of Molecular Sciences
  32. Neuroprotection of MAO-B inhibitor and dopamine agonist in Parkinson disease.
    Ping Kong, Benshu Zhang, Ping Lei, Xiaodong Kong, Shishuang Zhang, Dai Li, Yun Zhang · 2015 · Europe PMC (PubMed Central)
  33. Hydroxysafflor yellow A promotes α-synuclein clearance via regulating autophagy in rotenone-induced Parkinson’s disease mice
    Bing Han, Lijie Wang, Fenghua Fu, Zhenhua Wang, Leiming Zhang, Grace Jia Qi, Tian Wang · 2018 · Folia Neuropathologica
  34. Biomimetic Nanoparticles Enhance Recovery of Movement Disorders in Parkinson’s Disease by Improving Microglial Mitochondrial Homeostasis and Suppressing Neuroinflammation
    Liang Li, Chunbin Sun, Shanglin Cai, Zhongci Hang, Xiaoyu Gao, Liangxuan Hou, Luping Li, Yawen Wu, Cencan Xing, Hongwu Du · 2025 · ACS Applied Materials & Interfaces
  35. Treadmill exercise ameliorates impairment of spatial learning ability through enhancing dopamine expression in hypoxic ischemia brain injury in neonatal rats
    Chang-Youl Park, Shin‐Ho Lee, Bo-Kyun Kim, Mal‐Soon Shin, Chang‐Ju Kim, Hong K. Kim · 2013 · Journal of Exercise Rehabilitation
  36. Biologically active compounds from Lamiaceae family: Central nervous system effects
    Abeer Abdelhalim, Jane R. Hanrahan · 2021 · Studies in natural products chemistry
  37. Synthesis and biological evaluation of clovamide analogues with catechol functionality as potent Parkinson’s disease agents in vitro and in vivo
    Jiahao Feng, Xiaolong Hu, Xian-Yu Lv, Bao-Lin Wang, Jun Lin, Xiao‐Qi Zhang, Wen‐Cai Ye, Fei Xiong, Hao Wang · 2018 · Bioorganic & Medicinal Chemistry Letters
  38. Tetrahydrobiopterin Binding to Aromatic Amino Acid Hydroxylases. Ligand Recognition and Specificity
    Knut Teigen, Khanh Kim Dao, Jeffrey A. McKinney, Antonius C.F. Gorren, Bernd Mayer, Nils Åge Frøystein, Jan Haavik, Aurora Martı́nez · 2004 · Journal of Medicinal Chemistry
  39. Targeted reversal of iron deposition by highly active manganese-doped carbon dots in MRI-guided treatment of Parkinson's disease
    Huihui Wang, Maolin Zhang, Dongchuan Chu, Xueping Huang, Yu Shi, Yi Yang Zhao, Hang Qu, Dandan Li, Zhuobin Xu, Xiaohong Wang et al. · 2025 · Carbon
  40. Duration-dependence of the effect of treadmill exercise on hyperactivity in attention deficit hyperactivity disorder rats
    Eun‐Sang Ji, Chang‐Ju Kim, Jun Heon Park, Geon Ho Bahn · 2014 · Journal of Exercise Rehabilitation
  41. A Study on the Mechanism by Which MDMA Protects Against Dopaminergic Dysfunction After Minimal Traumatic Brain Injury (mTBI) in Mice
    Shahaf Edut, Vardit Rubovitch, Moshe Rehavi, Shaul Schreiber, Chaim G. Pick · 2014 · Journal of Molecular Neuroscience
  42. Genetics of Cerebellar and Neocortical Expansion in Anthropoid Primates: A Comparative Approach
    Peter W. Harrison, Stephen H. Montgomery · 2017 · Brain Behavior and Evolution
  43. Sodium-dependent glucose co-transporter-2 inhibitor empagliflozin exerts neuroprotective effects in rotenone-induced Parkinson’s disease model in zebrafish; mechanism involving ketogenesis and autophagy
    İsmail Ünal, Derya Cansız, Merih Beler, Zehra Sezer, Elif Güzel, Ebru Emekli‐Alturfan · 2023 · Brain Research
  44. Cytarabine prevents neuronal damage by enhancing AMPK to stimulate PINK1 / Parkin-involved mitophagy in Parkinson's disease model
    Lanxin Li, Yang Zhang, Zhengqian Chen, Can Xu, Zhongqiu Xu, Haitao Pei, Wei Wang, Ruyong Yao, Cui Hao · 2024 · European Journal of Pharmacology
  45. A Brief Overview of Tyrosine Hydroxylase and α-Synuclein in the Parkinsonian Brain
    Wajihullah Khan, Medha Priyadarshini, Haytham Ahmed Zakai, Mohammad Amjad Kamal, Qamre Alam · 2012 · CNS & Neurological Disorders - Drug Targets
  46. Iron modulates the activity of monoamine oxidase B in SH-SY5Y cells
    Huiru Lu, Jun Chen, Hui Huang, Mengxue Zhou, Qing xia Zhu, Shao Qin Yao, Zhifang Chai, Yi Hu · 2017 · BioMetals
  47. 7-Fluoro-1,3-diphenylisoquinoline reverses motor and non-motor symptoms induced by MPTP in mice: Role of striatal neuroinflammation
    Tuane Bazanella Sampaio, Marcel Henrique Marcondes Sari, Ana Paula Pesarico, Anderson C. Mantovani, Gilson Rogério Zeni, Cristina Wayne Nogueira · 2017 · European Journal of Pharmacology
  48. Long-Term Effects of Perinatal Exposure to a Glyphosate-Based Herbicide on Melatonin Levels and Oxidative Brain Damage in Adult Male Rats
    Daiane Cattani, Paula Pierozan, Ariane Zamoner, Eva B. Brittebo, Oskar Karlsson · 2023 · Antioxidants
  49. Supplementation with Bifidobacterium animalis subsp. lactis MH-022 for remission of motor impairments in a 6-OHDA-induced Parkinson's disease rat model by reducing inflammation, reshaping the gut microbiome, and fostering specific microbial taxa
    Shu‐Ping Tsao, Tu‐Hsueh Yeh, Ya‐Tin Lin, Chun Pan, Yuan Kun Lee, Chieh‐Hsi Wu, Hui-Yu Huang · 2024 · Food & Function
  50. Comparing the dopaminergic neurotoxic effects of benzylpiperazine and benzoylpiperazine
    Daniel P. Katz, Mohammed Majrashi, Sindhu Ramesh, Manoj Govindarajulu, Dwipayan Bhattacharya, Subhrajit Bhattacharya, Aimen Shlghom, Chastity Bradford, Vishnu D. Suppiramaniam, Jack DeRuiter et al. · 2017 · Toxicology Mechanisms and Methods
  51. A novel idea for establishing Parkinson’s disease mouse model by intranasal administration of paraquat
    Yibing Chen, Yanqiu Wang, Jia-Rong Wu, Yuan‐Lu Cui · 2020 · Neurological Research
  52. The 1-Tosylpentan-3-one Protects against 6-Hydroxydopamine-Induced Neurotoxicity
    Chien-Jen Kao, Wu-Fu Chen, Bo-Lin Guo, Chien‐Wei Feng, Han-Chun Hung, Wen-Ya Yang, Chun‐Sung Sung, Kuan‐Hao Tsui, Hsin Chu, Nan‐Fu Chen et al. · 2017 · International Journal of Molecular Sciences
  53. Inhibition of protein kinase ( PK ) C δ attenuates methamphetamine‐induced dopaminergic toxicity via upregulation of phosphorylation of tyrosine hydroxylase at S er40 by modulation of protein phosphatase 2 A and PKA
    Duy‐Khanh Dang, Chu Xuan Duong, Yunsung Nam, Eun‐Joo Shin, Yong Kwang Lim, Ji Hoon Jeong, Choon‐Gon Jang, Seung-Yeol Nah, Toshitaka Nabeshima, Hyoung‐Chun Kim · 2014 · Clinical and Experimental Pharmacology and Physiology
  54. Neurotoxicological Profiling of Paraquat in Zebrafish Model
    Seong Soon Kim, Kyu-Seok Hwang, Hyemin Kan, Jung Yoon Yang, Yuji Son, Dae‐Seop Shin, Byung Hoi Lee, Chong Hak Chae, Myung Ae Bae · 2022 · Neurochemical Research
  55. Intermittent Hypoxia and Experimental Parkinson’s Disease
    Maria V. Belikova, Evgenia E. Kolesnikova, Tatiana V. Serebrovskaya · 2012 · Springer eBooks
  56. Nitric oxide production and regulation of neuronal NOS in tyrosine hydroxylase containing neurons
    Qing Xu, David A. Wink, Carol A. Colton · 2004 · Experimental Neurology
  57. An Exploratory Evaluation of Tyrosine Hydroxylase Inhibition in Planaria as a Model for Parkinsonism
    David Prokai, Thinh Nguyen, Kurt Kamrowski, Ashwin Chandra, Tatjana Talamantes, Lewis Baxter, László Prókai · 2013 · International Journal of Molecular Sciences
  58. The role of iron in Parkinson's disease monkeys assessed by susceptibility weighted imaging and inductively coupled plasma mass spectrometry
    Shaojun Li, Yande Ren, Jin Li, Bin Cao, Chi Ma, Shanshan Qin, Xiangrong Li · 2019 · Life Sciences
  59. Identification of potential drugs for Parkinson's disease based on a sub-pathway method
    Ai-Guo Sun, Ai-Qi Lin, Shaoyue Huang, Di Huo, Chaohua Cong · 2014 · International Journal of Neuroscience
  60. Bifenthrin Caused Parkinson’s-Like Symptoms Via Mitochondrial Autophagy and Ferroptosis Pathway Stereoselectively in Parkin−/− Mice and C57BL/6 Mice
    Ying Zhang, Baorong Zhang · 2024 · Molecular Neurobiology
  61. Effects of Nogo-A Silencing on TNF-αand IL-6 Secretion and TH Downregulation in Lipopolysaccharide-Stimulated PC12 Cells
    Jianbin Zhong, Shengnuo Fan, Zhenwen Yan, Songhua Xiao, Limei Wan, Chibang Chen, Simin Zhong, Lu Liu, Jun Liu · 2015 · BioMed Research International
  62. Endogenous tetrahydroisoquinolines associated with Parkinson’s disease mimic the feedback inhibition of tyrosine hydroxylase by catecholamines
    Joachim Scholz, Karen Toska, Alexander Luborzewski, Astrid Maaß, Volker Schünemann, Jan Haavik, Andréas Moser · 2008 · FEBS Journal
  63. Squamosamide derivative FLZ protected tyrosine hydroxylase function in a chronic MPTP/probenecid mouse model of Parkinson’s disease
    Xiu-Qi Bao, Liang-Yu Wu, Xiaoliang Wang, Hua Sun, Dan Zhang · 2015 · Naunyn-Schmiedeberg s Archives of Pharmacology
  64. Neuroprotective effect of thiamine-producing lactic acid bacteria in a murine Parkinsonian model
    María del Milagro Terán, Daiana Pérez Visñuk, Graciela Savoy de Giori, Alejandra de Moreno de LeBlanc, Jean Guy LeBlanc · 2022 · Food & Function
  65. Quinpirole ameliorates nigral dopaminergic neuron damage in Parkinson’s disease mouse model through activating GHS-R1a/D2R heterodimers
    Tingting Tang, Mingxia Bi, Mei-ning Diao, Xiaoyi Zhang, Ling Chen, Xue Xiao, Qian Jiao, Xi Chen, Chunling Yan, Xixun Du et al. · 2023 · Acta Pharmacologica Sinica
  66. Subthalamic nucleus deep brain stimulation induces nigrostriatal dopaminergic plasticity in a stable rat model of Parkinson’s disease
    Charlotte Helf, Maria Kober, Franz Markert, Jennifer Lanto, Leonie Overhoff, Kathrin Badstübner-Meeske, Alexander Storch, Mareike Fauser · 2023 · Neuroreport
  67. N‐Propanoylmannosamine interferes with O‐GlcNAc modification of the tyrosine 3‐monooxygenase and stimulates dopamine secretion
    Kaya Bork, Christoph Kannicht, Sabine Nöhring, Werner G. Reutter, Wenke Weidemann, Gerald Warren Hart, Rüdiger Horstkorte · 2007 · Journal of Neuroscience Research
  68. Possible Roles of Epigenetics in Stem Cell Therapy for Parkinson’s Disease
    Cassandra Thompson, Paulina Otero, Bhairavi Srinageshwar, Robert B. Petersen, Gary Leo Dunbar, Julien Rossignol · 2020 · Epigenomics
  69. Chronic neuroprotective effects of low concentration lithium on SH-SY5Y cells: possible involvement of stress proteins and gene expression
    Riadh Nciri, Ezzeddine Bourogâa, Samira Jbahi, Mohamed Salah Allagui, Abdelfattah Elfeki, Christian Vincent, F. Croute · 2014 · Neural Regeneration Research
  70. Homologous Recombination in Human Embryonic Stem Cells
    Thomas P. Zwaka, James Alexander Thomson · 2004 · Elsevier eBooks
  71. Low-Level Tyrosine Hydroxylase (TH) Expression Allows for the Generation of Stable TH + Cell Lines of Human Neural Stem Cells
    Isabel Liste, Beatriz Navarro, Jens Leander Johansen, Carlos Bueno, Ana Villa, Teit Eliot Johansen, Alberto Martı́nez-Serrano · 2004 · Human Gene Therapy
  72. Elucidating the Neuroprotective Role of Formulated Camel α-Lactalbumin–Oleic Acid Complex by Curating the SIRT1 Pathway in Parkinson’s Disease Model
    Saba Ubaid, Mohammad Rumman, Babita Singh, Mohd. Sohail Akhtar, Abbas Ali Mahdi, Shivani Pandey · 2020 · ACS Chemical Neuroscience
  73. TIR-Domain-Containing Adapter-Inducing Interferon-β (TRIF) Is Essential for MPTP-Induced Dopaminergic Neuroprotection via Microglial Cell M1/M2 Modulation
    Minghui Shan, Sen Lin, Shurong Li, Yuchen Du, Haixia Zhao, Huarong Hong, Ming Yang, Xi Yang, Yongmei Wu, Liyi Ren et al. · 2017 · Frontiers in Cellular Neuroscience
  74. Neuroprotective effects of tadalafil on gerbil dopaminergic neurons following cerebral ischemia.
    Kwang Taek Kim, Kyung Jin Chung, Han Sae Lee, Il Gyu Ko, Chang‐Ju Kim, Yong Gil Na, Khae Hawn Kim · 2013 · PubMed Central
  75. Mouse Models of α-Synucleinopathy and Lewy Pathology
    Samuel Barbieri, Katja Hofele, Karl‐Heinz Wiederhold, A. Probst, Claudia Mistl, Simone Danner, Sabine Kauffmann, Bernd Sommer, Willibrordus Spooren, Markus Tolnay et al. · 2001 · Advances in experimental medicine and biology
  76. Beneficial effects of cysteamine in Thy1-α-Syn mice and induced pluripotent stem cells with a SNCA gene triplication
    Alberto Siddu, Linda Suzanne David, Nadine D Lauinger, Xiuqing Chen, Martine Saint‐Pierre, Melanie Alpaugh, Thomas M. Durcan, Francesca Cicchetti · 2020 · Neurobiology of Disease
  77. Lead specifically declines tyrosine hydroxylase activity to induce the onset of Parkinson's disease through disrupting dopamine biosynthesis in fly models
    Yue Niu, Yifan Pan, Yaqi Wang, Yongqi Fu, Zhangwu Zhao, Le Kang · 2024 · Environmental Pollution
  78. δ-Aminolevulinate Dehydratase Activity is Stimulated in a MPTP Mouse Model of Parkinson’s Disease: Correlation with Myeloperoxidase Activity
    Tuane Bazanella Sampaio, Marcel Henrique Marcondes Sari, Ana Paula Pesarico, Cristina Wayne Nogueira · 2016 · Cellular and Molecular Neurobiology
  79. Long-term therapeutic effects on parkinsonian rats of intrastriatal co-grafts with genetically engineered fibroblasts expressing tyrosine hydroxylase and glial cell line-derived neurotrophic factor
    Jingzhong Zhang, Yang Hui, Duan Deyi, Duan Chunli, Zhao Chunli, Xiaohong Sun, Jinlu Zhang, Qunyuan Xu · 2005 · International Journal of Neuroscience
  80. Current advances in combining stem cell and gene therapy for neurodegenerative diseases
    Ji-Yoon Hwang, Jeong-Seob Won, Hyun Nam, Hye Won Lee, Kyeung Min Joo · 2018 · Precision and Future Medicine
  81. Anthocyanin-Rich Blueberry Extract Ameliorates the Behavioral Deficits of MPTP-Induced Mouse Model of Parkinson’s Disease via Anti-Oxidative Mechanisms
    Feng Qian, Mengmeng Wang, Jianggang Wang, Chengbiao Lu · 2019 · Yangtze Medicine
  82. Inhibition of histone deacetylase promotes a neuroprotective mechanism in an experimental model of Parkinson’s disease
    Hang Li, Guolin Shi, Hao Zha, Liqing Zheng, Zhan Luo, Ying Wang · 2021 · Archives of Medical Science
  83. Transcriptional Regulation of the Tyrosine Hydroxylase Gene by Neurotensin in Human Neuroblastoma CHP212 Cells
    Mustapha Najimi, Emmanuel Hermans, William H. Rostène, Patricia Forgez · 2001 · Metabolic Brain Disease
  84. A Digital Atlas to Characterize the Mouse Brain Transcriptome
    James A. Carson, Tao Ju, Hui‐Chen Lu, Christina Thaller B, Mei Xu, Sarah L. Pallas, Michael C. Crair, Joe D. Warren, Wah Chiu, Gregor Eichele C · 2005 · PLoS Computational Biology
  85. Persistent Neurological Deficits in Mouse PASC Reveal Antiviral Drug Limitations
    Abhishek Kumar Verma, Shea A. Lowery, Li-Chin Lin, Eazhisaivallabi Duraisami, Juan E. Abrahante, Qiang Qiu, Marco M. Hefti, C. Ron Yu, Mark W. Albers, Stanley M. Perlman · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  86. Association of decreased triadin expression level with apoptosis of dopaminergic cells in Parkinson’s disease mouse model
    Min Hyung Seo, Sabina Lim, Sujung Yeo · 2021 · BMC Neuroscience
  87. Bacopaside-I ameliorates motor dysfunction and neurodegeneration in rat model of Parkinson’s disease
    Babita Singh, Shivani Pandey, Mohammad Rumman, Mrinal Gupta, Abbas Ali Mahdi · 2024 · Naunyn-Schmiedeberg s Archives of Pharmacology
  88. Zhichan powder regulates nigrostriatal dopamine synthesis and metabolism in Parkinson's disease rats.
    Qingwei Zhou, Jiajun Chen, Shihong Yi, Yongwei Lou, Weimin Tang, Yongmao Liu, Pengguo Zhang · 2012 · PubMed Central
  89. Is X-linked methyl-CpG binding protein 2 a new target for the treatment of Parkinson's disease.
    Teng Xie, Jie Zhang, Xian-hou Yuan, Jing Yang, Wei Jun Ding, Xin Huang, Yong Wu · 2013 · PubMed Central
  90. Evaluation of hybrid and pure DFT methods for the binding of novel ligands in the tyrosine hydroxylase enzyme
    Rebecca Evans, Larryn W. Peterson, Mauricio Cafiero · 2018 · Computational and Theoretical Chemistry
  91. Multiple Hits on Cerebral Folate, Tetrahydrobiopterin and Dopamine Metabolism in the Pathophysiology of Parkinson’s Disorder: A Limited Study of Post-Mortem Human Brain Tissues
    Dhruti Balakrishna Doddaballapur, Derren J. Heyes, Jaleel A. Miyan · 2025 · Metabolites
  92. Liposomal Form of L-Dopa and SH-Sy5y Cell-Derived Exosomes Modulate the Tyrosine Hydroxylase/Dopamine Receptor D2 Signaling Pathway in Parkinson's Rat Models
    Parastoo Zarrin, Mahmood Dehghani Ashkezari, Seyed Morteza Seifati · 2021 · Journal of Molecular Neuroscience
  93. The Role of Caffeine in Neurodegenerative Diseases
    Khanh vinh quốc Lương, Lan Nguyễn · 2014 · Elsevier eBooks
  94. In vitro and in vivo neuroprotective effect of novel mPGES-1 inhibitor in animal model of Parkinson’s disease
    Seyoung Yang, Eugene Huh, Gwang Hyun Moon, Junseong Ahn, Jiwon Woo, Hee-Soo Han, Hwi‐Ho Lee, Kyung‐Sook Chung, Kyung‐Tae Lee, Myung Sook Oh et al. · 2022 · Bioorganic & Medicinal Chemistry Letters
  95. ApoE isoform-specific differences in behavior and cognition associated with subchronic MPTP exposure
    Eileen Ruth S. Torres, Sydney Weber Boutros, Charles K. Meshul, Jacob Raber · 2020 · Learning & Memory
  96. Social defeat stress impairs systemic iron metabolism by activating the hepcidin–ferroportin axis
    Emiko Kasahara, Ayumi Nakamura, Kenki Morimoto, Shiho Ito, Mika Hori, Atsuo Sekiyama · 2024 · FASEB BioAdvances
  97. Vitamin D Associated with Exercise Can Be Used as a Promising Tool in Neurodegenerative Disease Protection
    Gabriele Farina, Clara Crescioli · 2025 · Molecules
  98. Combination antiviral and anti-inflammatory therapy mitigates persistent neurological deficits in mice post SARS-CoV-2 infection
    Abhishek Kumar Verma, Lu Tan, Noah Schuster, Skyler L. Moye, Li-Chun Lin, Shea A. Lowery, Eazhisaivallabi Duraisami, Juan E. Abrahante, Qiang Qiu, Marco H. Hefti et al. · 2026 · Proceedings of the National Academy of Sciences
  99. Tyrosine Metabolism Pathway Is Downregulated in Dopaminergic Neurons with LRRK2 Overexpression in Drosophila
    Jack Cheng, Bor‐Tsang Wu, Hsin‐Ping Liu, Wei‐Yong Lin · 2023 · International Journal of Molecular Sciences
  100. Tyrosine hydroxylase assay: a bioassay for aryl hydrocarbon receptor-active compounds based on tyrosine hydroxylase promoter activation
    Eiichi Akahoshi, Seiko Yoshimura, Saeko Uruno, Satoshi Itoh, Mitsuko Ishihara‐Sugano · 2012 · Toxicology Mechanisms and Methods