The DOI matches its Crossref record; 157 of the 157 references it cites were found in a registry or an index.
Glioblastoma, a Brief Review of History, Molecular Genetics, Animal Models and Novel Therapeutic Strategies
Abstract
Glioblastoma (GBM) is the most common and lethal primary brain tumor. Over the past few years tremendous genomic and proteomic characterization along with robust animal models of GBM have provided invaluable data that show that "GBM", although histologically indistinguishable from one another, are comprised of molecularly heterogenous diseases. In addition, robust pre-clinical models and a better understanding of the core pathways disrupted in GBM are providing a renewed optimism for novel strategies targeting these devastating tumors. Here, we summarize a brief history of the disease, our current molecular knowledge, lessons from animal models and emerging concepts of angiogenesis, invasion, and metabolism in GBM that may lend themselves to therapeutic targeting.
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1 retracted
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RetractedRadiotherapy Plus Concomitant and Adjuvant Temozolomide for Glioblastoma
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Comprehensive genomic characterization defines human glioblastoma genes and core pathways
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Self-citationMGMT Gene Silencing and Benefit from Temozolomide in Glioblastoma
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An Integrated Genomic Analysis of Human Glioblastoma Multiforme
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Cited by
Chen, X., Wanggou, S., Bodalia, A., Zhu, M., Dong, W., Fan, J. J., Yin, W. C., Min, H.-K., Hu, M., Draghici, D., et al. (2018) · Neuron · doi:10.1016/j.neuron.2018.09.046 · Cited by 401
Brandes, A. A., Carpentier, A. F., Kesari, S., Sepulveda-Sanchez, J. M., Wheeler, H. R., Chinot, O., Cher, L., Steinbach, J. P., Capper, D., Specenier, P., et al. (2016) · Neuro-Oncology · doi:10.1093/neuonc/now009 · Cited by 273
Ionizing Radiation and Glioblastoma Exosomes: Implications in Tumor Biology and Cell Migration
Arscott, W. T., Tandle, A. T., Zhao, S., Shabason, J. E., Gordon, I. K., Schlaff, C. D., Zhang, G., Tofilon, P. J., & Camphausen, K. A. (2013) · Translational Oncology · doi:10.1593/tlo.13640 · Cited by 229
mTOR-Dependent Cell Proliferation in the Brain
Ryskalin, L., Lazzeri, G., Flaibani, M., Biagioni, F., Gambardella, S., Frati, A., & Fornai, F. (2017) · BioMed Research International · doi:10.1155/2017/7082696 · Cited by 86
Metadata
- Authors
- Agnihotri, S., Burrell, K. E., Wolf, A., Jalali, S., Hawkins, C., Rutka, J. T., & Zadeh, G.
- Venue
- Archivum Immunologiae et Therapiae Experimentalis
- Publisher
- Walter de Gruyter GmbH
- Published
- 2012-12-07
- Volume
- 61
- Issue
- 1
- Pages
- 25-41
- ISSN
- 0004-069X (ISSN-L)
- 1661-4917
- OpenAlex
- W1972840121
- Cited by
- 272
- References
- 157
- FWCI
- 4.86
- Type
- journal article
- Language
- en
- Open access
- closed
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- Agnihotri, S., Burrell, K. E., Wolf, A., Jalali, S., Hawkins, C., Rutka, J. T., & Zadeh, G. (2013). Glioblastoma, a Brief Review of History, Molecular Genetics, Animal Models and Novel Therapeutic Strategies. Archivum Immunologiae et Therapiae Experimentalis. https://doi.org/10.1007/s00005-012-0203-0
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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