Cilioplasm is a cellular compartment for calcium signaling in response to mechanical and chemical stimuli

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Imaging neural activity in worms, flies and mice with improved GCaMP calcium indicators

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Bending the MDCK Cell Primary Cilium Increases Intracellular Calcium

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Endothelial Cilia Are Fluid Shear Sensors That Regulate Calcium Signaling and Nitric Oxide Production Through Polycystin-1

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Identification of Ciliary Localization Sequences within the Third Intracellular Loop of G Protein-coupled Receptors

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Removal of the MDCK Cell Primary Cilium Abolishes Flow Sensing

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Ciliary Polycystin-2 Is a Mechanosensitive Calcium Channel Involved in Nitric Oxide Signaling Cascades

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A size-exclusion permeability barrier and nucleoporins characterize a ciliary pore complex that regulates transport into cilia

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Cholangiocyte Cilia Detect Changes in Luminal Fluid Flow and Transmit Them Into Intracellular Ca2+ and cAMP Signaling

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Odorant Receptor Localization to Olfactory Cilia Is Mediated by ODR-4, a Novel Membrane-Associated Protein

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Chapter 13 Ciliary Dysfunction in Developmental Abnormalities and Diseases

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Analysis and modeling of the primary cilium bending response to fluid shear

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FAPP2, cilium formation, and compartmentalization of the apical membrane in polarized Madin–Darby canine kidney (MDCK) cells

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Loss of Polycystin-1 in Human Cyst-Lining Epithelia Leads to Ciliary Dysfunction

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PKHD1 protein encoded by the gene for autosomal recessive polycystic kidney disease associates with basal bodies and primary cilia in renal epithelial cells

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The cytoplasmic tail of fibrocystin contains a ciliary targeting sequence

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Mechanoregulation of intracellular Ca2+concentration is attenuated in collecting duct of monocilium-impairedorpkmice

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DISC1 Regulates Primary Cilia That Display Specific Dopamine Receptors

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Dopamine Receptor Type 5 in the Primary Cilia Has Dual Chemo- and Mechano-Sensory Roles

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Loss of primary cilia results in deregulated and unabated apical calcium entry in ARPKD collecting duct cells

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β1-Integrins in the primary cilium of MDCK cells potentiate fibronectin-induced Ca2+signaling

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Mechanisms regulating cilia growth and cilia function in endothelial cells

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Attenuated, flow-induced ATP release contributes to absence of flow-sensitive, purinergic Cai2+signaling in human ADPKD cyst epithelial cells

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Non-Motile Primary Cilia as Fluid Shear Stress Mechanosensors

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A Comparative Study of Embedded and Anesthetized Zebrafish in vivo on Myocardiac Calcium Oscillation and Heart Muscle Contraction

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Galectin-7 modulates the length of the primary cilia and wound repair in polarized kidney epithelial cells

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Tubular and cellular localization of the cardiac L-type calcium channel in rat kidney

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Overexpression of regucalcin enhances its nuclear localization and suppressesL-type Ca2+ channel and calcium-sensing receptor mRNA expressions in cloned normal rat kidney proximal tubular epithelial NRK52E cells

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Cellular signalling by primary cilia in development, organ function and disease

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Primary cilia are not calcium-responsive mechanosensors

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Primary cilium-dependent signaling mechanisms

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Intraciliary Calcium Oscillations Initiate Vertebrate Left-Right Asymmetry

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Genetically Encoded Fluorescent Indicators for Organellar Calcium Imaging

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The primary cilium functions as a mechanical and calcium signaling nexus

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Primary-cilium-dependent autophagy controls epithelial cell volume in response to fluid flow

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Vasopressin and disruption of calcium signalling in polycystic kidney disease

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Ciliary Mechanisms of Cyst Formation in Polycystic Kidney Disease

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G-Protein-Coupled Receptor Signaling in CiliaPreprint

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Primary cilia: Cell and molecular mechanosensors directing whole tissue function

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Function and regulation of primary cilia and intraflagellar transport proteins in the skeleton

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Lengthening primary cilia enhances cellular mechanosensitivity

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The native TRPP2-dependent channel of murine renal primary cilia

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The primary cilium as sensor of fluid flow: new building blocks to the model. A Review in the Theme: Cell Signaling: Proteins, Pathways and Mechanisms

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Signaling in the primary cilium through the lens of the Hedgehog pathway

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Signal transduction in primary cilia – analyzing and manipulating GPCR and second messenger signaling

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Fixation methods can differentially affect ciliary protein immunolabeling

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Pulsed electromagnetic fields stimulate osteogenic differentiation and maturation of osteoblasts by upregulating the expression of BMPRII localized at the base of primary cilium

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Structure and function of polycystins: insights into polycystic kidney disease

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Ciliary exclusion of Polycystin-2 promotes kidney cystogenesis in an autosomal dominant polycystic kidney disease model

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Polycystins and partners: proposed role in mechanosensitivity

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Polycystin and calcium signaling in cell death and survival

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The Roles of Primary Cilia in Cardiovascular Diseases

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The Roles of Primary cilia in Polycystic Kidney Disease

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Roles of dopamine receptor on chemosensory and mechanosensory primary cilia in renal epithelial cells

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Role of calcium in polycystic kidney disease: From signaling to pathology

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High shear stress amplitude in combination with prolonged stimulus duration determine induction of osteoclast formation by hematopoietic progenitor cells

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The Future of Polycystic Kidney Disease Research—As Seen By the 12 Kaplan Awardees

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Biomechanical cues as master regulators of hematopoietic stem cell fate

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Calcium channels in primary cilia

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A mutation affecting polycystin-1 mediated heterotrimeric G-protein signaling causes PKD

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Convergence of Calcium Channel Regulation and Mechanotransduction in Skeletal Regenerative Biomaterial Design

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Sensory primary cilium is a responsive cAMP microdomain in renal epithelia

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The β-cell primary cilium is an autonomous Ca2+ compartment for paracrine GABA signaling

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Adenylyl cyclase 6 mediates loading‐induced bone adaptation in vivo

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Ciliotherapy: Remote Control of Primary Cilia Movement and Function by Magnetic Nanoparticles

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The nphp-2 and arl-13 Genetic Modules Interact to Regulate Ciliogenesis and Ciliary Microtubule Patterning in C. elegans

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L-type calcium channel modulates cystic kidney phenotype

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Electrical Signaling in Motile and Primary Cilia

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Mesenchymal stem cell mechanotransduction is cAMP dependent and regulated by adenylyl cyclase 6 and the primary cilium

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An intelligent nano-antenna: Primary cilium harnesses TRP channels to decode polymodal stimuli

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Role of the polycystins as mechanosensors of extracellular stiffness

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The role of cilia in the pathogenesis of cystic kidney disease

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Intracellular Calcium Mobilization Is Required for Sonic Hedgehog Signaling

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Functions of Endothelial Cilia in the Regulation of Vascular Barriers

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Protein composition and movements of membrane swellings associated with primary cilia

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Nephronophthisis-Pathobiology and Molecular Pathogenesis of a Rare Kidney Genetic Disease

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Calcium dynamics at the neural cell primary cilium regulate Hedgehog signaling–dependent neurogenesis in the embryonic neural tube

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Sensing a Sensor: Identifying the Mechanosensory Function of Primary Cilia

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Primary Cilia in Cystic Kidney Disease

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Genes and mechanisms of heterotaxy: patients drive the search

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Primary cilium–mediated mechanotransduction in cartilage chondrocytes

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Using Zebrafish to Study Kidney Development and Disease

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Biophysics and biofluid dynamics of primary cilia: evidence for and against the flow-sensing function

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The TRPP2-dependent channel of renal primary cilia also requires TRPM3

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Flow stimulated endocytosis in the proximal tubule

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Fluid shear stress generates a unique signaling response by activating multiple TGFβ family type I receptors in osteocytes

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The mechanosensitive BKα/β1 channel localizes to cilia of principal cells in rabbit cortical collecting duct (CCD)

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RAPAMYCIN INCREASES LENGTH AND MECHANOSENSORY FUNCTION OF PRIMARY CILIA IN RENAL EPITHELIAL AND VASCULAR ENDOTHELIAL CELLS.

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The zebrafish Kupffer's vesicle as a model system for the molecular mechanisms by which the lack of Polycystin-2 leads to stimulation of CFTR

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High-specificity protection against radiation-induced bone loss by a pulsed electromagnetic field

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Developmental signaling: Does it bridge the gap between cilia dysfunction and renal cystogenesis?

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Primary Cilia and Atherosclerosis

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Primary Cilium Regulates CaV1.2 Expression Through Wnt Signaling

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Primary cilia are sensors of electrical field stimulation to induce osteogenesis of human adipose‐derived stem cells

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The electric fence to cell‐cycle progression: Do local changes in membrane potential facilitate disassembly of the primary cilium?

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The Role of the Primary Cilium in Sensing Extracellular pH

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Three types of ependymal cells with intracellular calcium oscillation are characterized by distinct cilia beating properties

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Loss of primary cilia increases polycystin-2 and TRPV4 and the appearance of a nonselective cation channel in the mouse cortical collecting duct

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Primary cilia in hard tissue development and diseases

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HIF Stabilization Weakens Primary Cilia

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Ciliary mechanosensation – roles of polycystins and mastigonemes

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Intermittent Exposure to a 16 Hz Extremely Low Frequency Pulsed Electromagnetic Field Promotes Osteogenesis In Vitro through Activating Piezo 1-Induced Ca2+ Influx in Osteoprogenitor Cells

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Parkinsonism Sac domain mutation in Synaptojanin-1 affects ciliary properties in iPSC-derived dopaminergic neurons

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Novel Insights into the Development and Function of Cilia Using the Advantages of the Paramecium Cell and Its Many Cilia

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The spatiotemporal heterogeneity of the biophysical microenvironment during hematopoietic stem cell development: from embryo to adult

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Chronic Hypobaric Hypoxia Modulates Primary Cilia Differently in Adult and Fetal Ovine Kidneys

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Biomechanical regulation of endothelial function in atherosclerosis

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Regenerative Calcium Currents in Renal Primary Cilia

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Calcium–axonemal microtubuli interactions underlie mechanism(s) of primary cilia morphological changes

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Primary cilia have a length-dependent persistence length

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Chemical-Free Technique to Study the Ultrastructure of Primary Cilium

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Aldosterone controls primary cilium length and cell size in renal collecting duct principal cells

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New Insights into the Molecular Mechanisms Targeting Tubular Channels/Transporters in PKD Development

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Live Imaging of the Ependymal Cilia in the Lateral Ventricles of the Mouse Brain

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Primary cilium: a paradigm for integrating mathematical modeling with experiments and numerical simulations in mechanobiology

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New insights in the pathophysiology and treatment of hypertension in autosomal dominant polycystic kidney disease

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Mechano-Sensing and shear stress-shielding by endothelial primary cilia: structure, composition, and function

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The Role of Integrin β1D Mislocalization in the Pathophysiology of Calpain 3-Related Limb–Girdle Muscular Dystrophy

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5.6 Effects of Mechanical Stress on Cells ☆

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Functional Study of the Primary Cilia in ADPKD

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Neuronal guidance behaviours: the primary cilium perspective

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Regulation of Calcium Signaling by Primary Cilia and Its Role in Polycystic Kidney Disease Pathogenesis

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Calcium Signaling Inside Cilia Upon Mechanical Bending

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Mechanosensory function of Cav1.2 calcium channel in renal primary cilia

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Calcium signaling in cilia and ciliary-mediated intracellular calcium signaling: Are they independent or coordinated molecular events?

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Primary cilia are not calcium-responsive mechanosensors

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